التفاصيل البيبلوغرافية
| العنوان: |
A cross sectional study of asymptomatic cardiac findings in non insulin dependent diabetes mellitus. |
| المؤلفون: |
Shrivastava, Kislay, Saxena, Harshita |
| المصدر: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 5, p1232-1236, 5p |
| مصطلحات موضوعية: |
TYPE 2 diabetes, DIABETIC angiopathies, TREADMILL exercise tests, DIABETES, MYOCARDIAL infarction, CORONARY artery disease, DIASTOLE (Cardiac cycle) |
| مصطلحات جغرافية: |
INDIA |
| مستخلص: |
Introduction: Diabetes mellitus, is an ever progressive, disease. It is also considered as coronary artery disease equivalent. People with type 2 diabetes mellitus (T2DM) have a higher cardiovascular morbidity and mortality, and are disproportionately affected by CVD compared with non-diabetic subjects1,8. Diabetic vascular disease is responsible for two to four-fold rise in the occurrence of coronary artery disease (CAD) and stroke, and two-eightfold improve in the risk of heart failure2. It affects roughly one-third of all acute myocardial infarction patients. According to the global burden of disease assessment, India is expected to have significant increase in diabetes prevalence and subsequently coronary artery disease. Materials and Methods: This cross-sectional study was done at Venkateshwara institute of medical sciences, Gajraula among 50 patients who attended the institute (both in and out patient between January 2022 and august 2022. Initial step consisted of consent for study followed by medical history, physical and systemic examinations. After the preliminaries, routine and detailed investigations were done. All those who were asymptomatic with regard to cardiac symptoms such as dyspnea, chest pain etc and were having non-insulin dependent diabetes mellitus for one year or more duration were included. Investigations done included CBC, Renal function test, lipid profile, fasting and post prandial blood sugar, fundus examination to assess end organ damage, ECG, echocardiography and treadmill stress test or dobutamine stress test. Results: This study included 50 NIDDM patients. There was a little difference among males (n=28) and females (n=22) in the study which correlates with other studies that there is no sex difference in the incidence of Diabetes. With regard to age group 30 patients (60%) belong to 5th decade. 40 % patients In this study (20 out of 50) had diabetes less than 5 years, 20 patients (40 %) had diabetes of 5-10-year duration and 10 patients (20%) had diabetes more than 10 years. 14 (28%) patients showed silent myocardial ischemia on TMT or Stress echo. 2 patients (4%) developed minor angina on stress test but were able to complete the test. 3 (6%) patient showed baseline regional wall motion abnormality with/or LV systolic dysfunction. Conclusion: There was only minor difference in gender distribution in favor of males. As per age distribution the majority of the patients were in 5th decade. Our study showed lipid abnormalities included Hypertriglyceridemia as most prevalent 25 (50%), however LDL level was more than 130mg/dl in 20 (40%) of patients as well. With stress tests, 28% (14 out of 50) of patients had asymptomatic inducible ischemia and 2 patients (4%) developed minor angina on stress test but were able to complete the test. 3 (6%) patient showed baseline regional wall motion abnormality with/or LV systolic dysfunction. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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