التفاصيل البيبلوغرافية
| العنوان: |
The applicability of the digit wrinkle scan to quantify sympathetic nerve function |
| المؤلفون: |
Maurice Sopacua, Carla M.L. Gorissen-Brouwers, Bianca T.A. de Greef, Isis B.T. Joosten, Catharina G. Faber, Ingemar S.J. Merkies, Janneke G.J. Hoeijmakers |
| المساهمون: |
Klinische Neurowetenschappen, RS: MHeNs - R3 - Neuroscience, MUMC+: MA Niet Med Staf Neurologie (9), RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: MA Med Staf Spec Neurologie (9) |
| المصدر: |
Clinical Neurophysiology Practice, 7, 115-119. Elsevier BV |
| سنة النشر: |
2022 |
| مصطلحات موضوعية: |
Inter-observer reliability, Neurology, Physiology (medical), DIAGNOSTIC-CRITERIA, DENSITY, Neurology (clinical), 5-point scale, SMALL FIBER NEUROPATHY, Digit wrinkle scan, Digit vasoconstriction, INDICATOR, Autonomic function, WATER IMMERSION |
| الوصف: |
Objective: Stimulated skin wrinkling test (SSW) has been launched as a non-invasive diagnostic procedure. However, no normative age dependent values have been reported that can be applied in clinical practice. The objectives of the study were to (1) collect age-dependent normative values according to the 5-point scale assessment for the SSW, to (2) determine reliability scores for the obtained norm values, and to (3) introduce a new digital method for SSW assessment, the Digit Wrinkle Scan© (DWS©) for detection of wrinkles in a more quantitative manner.Methods: Firstly, 82 healthy participants were included, divided in 5 age groups. The participants underwent SSW using lidocaine and prilocaine topical cream. Secondly, 35 healthy participants were included to test whether the DWS© could be a novel manner to assess the grade of wrinkling quantitatively. We determined the inter-observer reliability of both methods. Also, the intra-observer reliability was calculated for the DWS©.Results: We found a decrease in normative values over age. The inter-observer reliability of assessment by the 5-point scale method was moderate after SSW (Cohen's k: 0.53). Results of the DWS© indicate that total wrinkle length per mm2 showed moderate to good agreement for the 4th and 5th digits after SSW, and a low agreement for the other digits.Conclusions: Age-dependent normative values were obtained according to the 5-point scale, but its clinical application is doubtful since we found a moderate inter-observer reliability. We introduced the DWS© as a possible new method in order to quantify the grade of wrinkling.Significance: We found unsatisfactory reliability scores, which hampers its usefulness for clinical practice. |
| تدمد: |
2467-981X |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99da569cfb344b85a3cea8fa6a5059bTest
https://pubmed.ncbi.nlm.nih.gov/35434427Test |
| حقوق: |
OPEN |
| رقم الانضمام: |
edsair.doi.dedup.....e99da569cfb344b85a3cea8fa6a5059b |
| قاعدة البيانات: |
OpenAIRE |
