Bacillus cereus, a serious cause of nosocomial infections: Epidemiologic and genetic survey
| العنوان: | Bacillus cereus, a serious cause of nosocomial infections: Epidemiologic and genetic survey |
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| المؤلفون: | Glasset, Benjamin, Herbin, Sabine, Granier, Sophie A., Cavalié, Laurent, Lafeuille, Emilie, Guérin, Cyprien, Ruimy, Raymond, Casagrande-Magne, Florence, Levast, Marion, Chautemps, Nathalie, Decousser, Jean-Winoc, Belotti, Laure, Pelloux, Isabelle, Robert, Jerôme, Brisabois, Anne, Ramarao, Nalini |
| المساهمون: | MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Laboratory for Food Safety, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Service Bactériologie-Hygiène, Centre Hospitalier Universitaire de Toulouse, Institut de Recherche en Santé Digestive (IRSD ), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Pierre et Marie Curie - Paris 6 (UPMC), Laboratoire de bactériologie-hygiène, Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Mathématiques et Informatique Appliquées du Génome à l'Environnement [Jouy-En-Josas] (MaIAGE), Institut National de la Recherche Agronomique (INRA), Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice (CHU Nice), Centre Hospitalier de Chambéry (C.H.de Chambéry), Laboratoire d'hygiene, Mairie de Paris, Laboratoire d'Hygiène Hospitalière, Université d'Auvergne - Clermont-Ferrand I (UdA), CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF), Laboratoire de sécurité des aliments de Maisons-Alfort (LSAl), Service Bactériologie et hygiène [CHU Toulouse], Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), ProdInra, Migration, Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| المصدر: | Plos One 5 (13), . (2018) PLoS ONE, Vol 13, Iss 5, p e0194346 (2018) PLoS ONE PLoS ONE, Public Library of Science, 2018, 13 (5), ⟨10.1371/journal.pone.0194346⟩ PLoS ONE, 2018, 13 (5), ⟨10.1371/journal.pone.0194346⟩ |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Physiology, Nosocomial Infections, lcsh:Medicine, Bacillus, Pathology and Laboratory Medicine, Pediatrics, Neonatal Care, caractérisation moléculaire, Antibiotics, Surveys and Questionnaires, Medicine and Health Sciences, caractérisation souche bactérienne, Child, lcsh:Science, Aged, 80 and over, Cross Infection, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Antimicrobials, Drugs, Genomics, Middle Aged, Bacterial Pathogens, Body Fluids, Anti-Bacterial Agents, Blood, Infectious Diseases, Phenotype, Medical Microbiology, Child, Preschool, maladie nosocomiale, donnée clinique, Female, Pathogens, Anatomy, Neonatal Sepsis, Research Article, Adult, Adolescent, Médecine humaine et pathologie, Microbiology, Young Adult, Signs and Symptoms, donnée épidémiologique, Diagnostic Medicine, Microbial Control, Sepsis, Humans, Microbial Pathogens, Aged, Pharmacology, Bacteria, lcsh:R, fungi, bacillus cereus, Organisms, Infant, Newborn, Biology and Life Sciences, Neonates, Genetic Variation, Infant, Health Care, traitement antibiotique, bacteria, lcsh:Q, Human health and pathology, Neonatology, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Developmental Biology |
| الوصف: | communiqué de presse : https://presse.inserm.fr/infections-nosocomiales-la-bacterie-bacillus-cereus-peut-aussi-en-etre-la-cause/31499Test/; International audience; Bacillus cereus is the 2nd most frequent bacterial agent responsible for food-borne outbreaks in France and the 3rd in Europe. In addition, local and systemic infections have been reported, mainly describing individual cases or single hospital setting. The real incidence of such infection is unknown and information on genetic and phenotypic characteristics of the incriminated strains is generally scarce. We performed an extensive study of B. cereus strains isolated from patients and hospital environments from nine hospitals during a 5-year study, giving an overview of the consequences, sources and pathogenic patterns of B. cereus clinical infections. We demonstrated the occurrence of several hospital-cross-contaminations. Identical B. cereus strains were recovered from different patients and hospital environments for up to 2 years. We also clearly revealed the occurrence of inter hospital contaminations by the same strain. These cases represent the first documented events of nosocomial epidemy by B. cereus responsible for intra and inter hospitals contaminations. Indeed, contamination of different patients with the same strain of B. cereus was so far never shown. In addition, we propose a scheme for the characterization of B. cereus based on biochemical properties and genetic identification and highlight that main genetic signatures may carry a high pathogenic potential. Moreover, the characterization of antibiotic resistance shows an acquired resistance phenotype for rifampicin. This may provide indication to adjust the antibiotic treatment and care of patients |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::06c41360b50d11258523179accf94332Test http://prodinra.inra.fr/record/437948Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid.dedup....06c41360b50d11258523179accf94332 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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