المؤلفون: Tobias, Deirdre K, Merino, Jordi, Ahmad, Abrar, Aiken, Catherine, Benham, Jamie L, Bodhini, Dhanasekaran, Clark, Amy L, Colclough, Kevin, Corcoy, Rosa, Cromer, Sara J, Duan, Daisy, Felton, Jamie L, Francis, Ellen C, Gillard, Pieter, Gingras, Véronique, Gaillard, Romy, Haider, Eram, Hughes, Alice, Ikle, Jennifer M, Jacobsen, Laura M, Kahkoska, Anna R, Kettunen, Jarno LT, Kreienkamp, Raymond J, Lim, Lee-Ling, Männistö, Jonna ME, Massey, Robert, Mclennan, Niamh-Maire, Miller, Rachel G, Morieri, Mario Luca, Most, Jasper, Naylor, Rochelle N, Ozkan, Bige, Patel, Kashyap Amratlal, Pilla, Scott J, Prystupa, Katsiaryna, Raghavan, Sridharan, Rooney, Mary R, Schön, Martin, Semnani-Azad, Zhila, Sevilla-Gonzalez, Magdalena, Svalastoga, Pernille, Takele, Wubet Worku, Tam, Claudia Ha-ting, Thuesen, Anne Cathrine B, Tosur, Mustafa, Wallace, Amelia S, Wang, Caroline C, Wong, Jessie J, Yamamoto, Jennifer M, Young, Katherine, Amouyal, Chloé, Andersen, Mette K, Bonham, Maxine P, Chen, Mingling, Cheng, Feifei, Chikowore, Tinashe, Chivers, Sian C, Clemmensen, Christoffer, Dabelea, Dana, Dawed, Adem Y, Deutsch, Aaron J, Dickens, Laura T, DiMeglio, Linda A, Dudenhöffer-Pfeifer, Monika, Evans-Molina, Carmella, Fernández-Balsells, María Mercè, Fitipaldi, Hugo, Fitzpatrick, Stephanie L, Gitelman, Stephen E, Goodarzi, Mark O, Grieger, Jessica A, Guasch-Ferré, Marta, Habibi, Nahal, Hansen, Torben, Huang, Chuiguo, Harris-Kawano, Arianna, Ismail, Heba M, Hoag, Benjamin, Johnson, Randi K, Jones, Angus G, Koivula, Robert W, Leong, Aaron, Leung, Gloria KW, Libman, Ingrid M, Liu, Kai, Long, S Alice, Lowe, William L, Morton, Robert W, Motala, Ayesha A, Onengut-Gumuscu, Suna, Pankow, James S, Pathirana, Maleesa, Pazmino, Sofia, Perez, Dianna, Petrie, John R, Powe, Camille E, Quinteros, Alejandra, Jain, Rashmi, Ray, Debashree, Ried-Larsen, Mathias

المصدر: Nature Medicine. 29(10)

مصطلحات موضوعية: Health Services and Systems, Biomedical and Clinical Sciences, Health Sciences, Health Services, Diabetes, Clinical Research, Pediatric, Metabolic and endocrine, Good Health and Well Being, Humans, Precision Medicine, Consensus, Diabetes Mellitus, Evidence-Based Medicine, Medical and Health Sciences, Immunology, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/43n7x223Test

المؤلفون: Srinivasan, Shylaja, Chen, Ling, Udler, Miriam, Todd, Jennifer, Kelsey, Megan M, Haymond, Morey W, Arslanian, Silva, Zeitler, Philip, Gubitosi-Klug, Rose, Nadeau, Kristen J, Kutney, Katherine, White, Neil H, Li, Josephine H, Perry, James A, Kaur, Varinderpal, Brenner, Laura, Mercader, Josep M, Dawed, Adem, Pearson, Ewan R, Yee, Sook-Wah, Giacomini, Kathleen M, Pollin, Toni, Florez, Jose C

مصطلحات موضوعية: Paediatrics, Biomedical and Clinical Sciences, Clinical Sciences, Prevention, Diabetes, Human Genome, Genetics, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Adult, Humans, Adolescent, Metformin, Diabetes Mellitus, Type 2, C-Peptide, Treatment Failure, Genetic Variation, Blood Glucose, Hypoglycemic Agents, Paediatrics and Reproductive Medicine, Endocrinology & Metabolism, Clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4sk0628gTest

المؤلفون: Dawed, Adem Y, Yee, Sook Wah, Zhou, Kaixin, van Leeuwen, Nienke, Zhang, Yanfei, Siddiqui, Moneeza K, Etheridge, Amy, Innocenti, Federico, Xu, Fei, Li, Josephine H, Beulens, Joline W, van der Heijden, Amber A, Slieker, Roderick C, Chang, Yu-Chuan, Mercader, Josep M, Kaur, Varinderpal, Witte, John S, Lee, Ming Ta Michael, Kamatani, Yoichiro, Momozawa, Yukihide, Kubo, Michiaki, Palmer, Colin NA, Florez, Jose C, Hedderson, Monique M, Hart, Leen MT, Giacomini, Kathleen M, Pearson, Ewan R, investigators:, MetGen Plus, Pearson, Ewan, Dawed, Adem, Holman, Rury, Coleman, Ruth, Hart, Leen T, Slieker, Roderick, Beulens, Joline, van der Heijden, Amber, Nijpels, Giel, Elders, Petra, Rutters, Femke, Stricker, Bruno, Ahmadizar, Fariba, de Keyser, Catherine, Koov, Adriaan, Out, Mattijs, Kloviņš, Jānis, Zaharenko, Linda, Javorsky, Martin, Tkac, Ivan, Florez, Jose, Giacomini, Kathy, Hedderson, Monique, Motsinger-Reif, Alison, Wagner, Michael, Semiz, Sabina, Dujic, Tanja, Christensen, Mette, Brøsen, Kim, Waterworth, Dawn, Ehm, Meg, Ma, Ronald, Psaty, Bruce, Floyd, James

المصدر: Diabetes Care. 44(12)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Prevention, Diabetes, Human Genome, Genetics, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Metabolic and endocrine, Blood Glucose, Diabetes Mellitus, Type 2, Genome-Wide Association Study, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Likelihood Functions, Liver-Specific Organic Anion Transporter 1, Metformin, Sulfonylurea Compounds, for MetGen Plus, for the DIRECT Consortium, MetGen Plus investigators:

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1pj67106Test

المؤلفون: Li, Josephine H, Perry, James A, Jablonski, Kathleen A, Srinivasan, Shylaja, Chen, Ling, Todd, Jennifer N, Harden, Maegan, Mercader, Josep M, Pan, Qing, Dawed, Adem Y, Yee, Sook Wah, Pearson, Ewan R, Giacomini, Kathleen M, Giri, Ayush, Hung, Adriana M, Xiao, Shujie, Williams, Keoki L, Franks, Paul W, Hanson, Robert L, Kahn, Steven E, Knowler, William C, Pollin, Toni I, Florez, Jose C

المصدر: Center for Individualized and Genomic Medicine Research Articles

مصطلحات موضوعية: Humans, Metformin, Diabetes Mellitus, Type 2, Genome-Wide Association Study, Prediabetic State, Genetic Variation, Polymorphism, Single Nucleotide

العلاقة: https://scholarlycommons.henryford.com/cigmr_articles/16Test; http://sfxhosted.exlibrisgroup.com/hfhs?sid=Entrez:PubMed&id=pmid:36525397Test

الإتاحة: https://scholarlycommons.henryford.com/cigmr_articles/16Test
http://sfxhosted.exlibrisgroup.com/hfhs?sid=Entrez:PubMed&id=pmid:36525397Test

المؤلفون: Koivula, Robert W, Forgie, Ian M, Kurbasic, Azra, Viñuela, Ana, Heggie, Alison, Giordano, Giuseppe N, Hansen, Tue H, Hudson, Michelle, Koopman, Anitra DM, Rutters, Femke, Siloaho, Maritta, Allin, Kristine H, Brage, Søren, Brorsson, Caroline A, Dawed, Adem Y, De Masi, Federico, Groves, Christopher J, Kokkola, Tarja, Mahajan, Anubha, Perry, Mandy H, Rauh, Simone P, Ridderstråle, Martin, Teare, Harriet JA, Thomas, E Louise, Tura, Andrea, Vestergaard, Henrik, White, Tom, Adamski, Jerzy, Bell, Jimmy D, Beulens, Joline W, Brunak, Søren, Dermitzakis, Emmanouil T, Froguel, Philippe, Frost, Gary, Gupta, Ramneek, Hansen, Torben, Hattersley, Andrew, Jablonka, Bernd, Kaye, Jane, Laakso, Markku, McDonald, Timothy J, Pedersen, Oluf, Schwenk, Jochen M, Pavo, Imre, Mari, Andrea, McCarthy, Mark I, Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Franks, Paul W, IMI DIRECT Consortium

مصطلحات موضوعية: Diet, Ectopic fat, Genome, Glycaemic control, Insulin secretion, Insulin sensitivity, Personalised medicine, Physical activity, Prediabetes, Type 2 diabetes, Aged, Biomarkers, Blood Glucose, Cohort Studies, Diabetes Mellitus, Type 2, Female, Glucose, Glucose Tolerance Test, Humans, Male, Metformin, Middle Aged, Prediabetic State, Prospective Studies

وصف الملف: Print-Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/292050Test

الإتاحة: https://doi.org/10.17863/CAM.39203Test
https://www.repository.cam.ac.uk/handle/1810/292050Test

المؤلفون: Dawed, Adem Y, Zhou, Kaixin, van Leeuwen, Nienke, Mahajan, Anubha, Robertson, Neil, Koivula, Robert, Elders, Petra J M, Rauh, Simone P, Jones, Angus G, Holl, Reinhard W, Stingl, Julia C, Franks, Paul W, McCarthy, Mark I, 't Hart, Leen M, Pearson, Ewan R

المصدر: Dawed , A Y , Zhou , K , van Leeuwen , N , Mahajan , A , Robertson , N , Koivula , R , Elders , P J M , Rauh , S P , Jones , A G , Holl , R W , Stingl , J C , Franks , P W , McCarthy , M I , 't Hart , L M , Pearson , E R & IMI-DIRECT consortium 2019 , ' Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and ....

مصطلحات موضوعية: Aged, Alleles, Diabetes Mellitus, Type 2/drug therapy, Drug Hypersensitivity/genetics, Equilibrative Nucleoside Transport Proteins/genetics, Female, Gastrointestinal Diseases/chemically induced, Genetic Association Studies, Humans, Hypoglycemic Agents/adverse effects, Male, Metformin/adverse effects, Middle Aged, Organic Cation Transporter 1/genetics, Polymorphism, Single Nucleotide, Risk Factors

الإتاحة: https://doi.org/10.2337/dc18-2182Test
https://curis.ku.dk/portal/da/publications/variation-in-the-plasma-membrane-monoamine-transporter-pmat-encoded-by-slc29a4-and-organic-cation-transporter-1-oct1-encoded-by-slc22a1-and-gastrointestinal-intolerance-to-metformin-in-type-2-diabetesTest(ba6e9b33-1dc1-4af3-b1cf-575f27ae0199).html
https://www.biorxiv.org/content/biorxiv/early/2018/10/06/436980.full.pdfTest

المؤلفون: Atabaki-Pasdar, N, Ohlsson, M, Vinuela, A, Frau, F, Pomares-Millan, H, Haid, M, Jones, AG, Thomas, EL, Koivula, RW, Kurbasic, A, Mutie, PM, Fitipaldi, H, Fernandez, J, Dawed, AY, Giordano, GN, Forgie, IM, McDonald, TJ, Rutters, F, Cederberg, H, Chabanova, E, Dale, M, Masi, FD, Thomas, CE, Allin, KH, Hansen, TH, Heggie, A, Hong, M-G, Elders, PJM, Kennedy, G, Kokkola, T, Pedersen, HK, Mahajan, A, McEvoy, D, Pattou, F, Raverdy, V, Haussler, RS, Sharma, S, Thomsen, HS, Vangipurapu, J, Vestergaard, H, 't Hart, LM, Adamski, J, Musholt, PB, Brage, S, Brunak, S, Dermitzakis, E, Frost, G, Hansen, T, Laakso, M, Pedersen, O, Ridderstrale, M, Ruetten, H, Hattersley, AT, Walker, M, Beulens, JWJ, Mari, A, Schwenk, JM, Gupta, R, McCarthy, MI, Pearson, ER, Bell, JD, Pavo, I, Franks, PW

المساهمون: Epidemiology and Data Science, General practice, APH - Health Behaviors & Chronic Diseases, Amsterdam Reproduction & Development (AR&D), ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, APH - Aging & Later Life, Atabaki-Pasdar, Naeimeh [0000-0001-7229-1888], Ohlsson, Mattias [0000-0003-1145-4297], Viñuela, Ana [0000-0003-3771-8537], Pomares-Millan, Hugo [0000-0001-9245-4576], Haid, Mark [0000-0001-6118-1333], Jones, Angus G. [0000-0002-0883-7599], Thomas, E. Louise [0000-0003-4235-4694], Koivula, Robert W. [0000-0002-1646-4163], Kurbasic, Azra [0000-0002-1910-2619], Fitipaldi, Hugo [0000-0001-5352-2134], Dawed, Adem Y. [0000-0003-0224-2428], Forgie, Ian M. [0000-0002-8800-6145], Cederberg, Henna [0000-0003-2901-9373], Dale, Matilda [0000-0002-5788-7744], Masi, Federico De [0000-0003-4859-4170], Thomas, Cecilia Engel [0000-0001-6201-6380], Allin, Kristine H. [0000-0002-6880-5759], Hansen, Tue H. [0000-0001-5948-8993], Elders, Petra J. M. [0000-0002-5907-7219], Kennedy, Gwen [0000-0002-9856-3236], Kokkola, Tarja [0000-0002-3303-3912], Pedersen, Helle Krogh [0000-0001-9609-7377], Mahajan, Anubha [0000-0001-5585-3420], McEvoy, Donna [0000-0003-1546-5567], Häussler, Ragna S. [0000-0003-1664-8875], Vangipurapu, Jagadish [0000-0001-6657-2659], Vestergaard, Henrik [0000-0003-3090-269X], ‘t Hart, Leen M. [0000-0003-4401-2938], Brage, Soren [0000-0002-1265-7355], Frost, Gary [0000-0003-0529-6325], Hansen, Torben [0000-0001-8748-3831], Hattersley, Andrew T. [0000-0001-5620-473X], Mari, Andrea [0000-0002-1436-5591], Schwenk, Jochen M. [0000-0001-8141-8449], Gupta, Ramneek [0000-0001-6841-6676], McCarthy, Mark I. [0000-0002-4393-0510], Pearson, Ewan R. [0000-0001-9237-8585], Bell, Jimmy D. [0000-0003-3804-1281], Franks, Paul W. [0000-0002-0520-7604], Apollo - University of Cambridge Repository, HUS Abdominal Center, Clinicum, Department of Medicine, Endokrinologian yksikkö, Jones, Angus G [0000-0002-0883-7599], Thomas, E Louise [0000-0003-4235-4694], Koivula, Robert W [0000-0002-1646-4163], Dawed, Adem Y [0000-0003-0224-2428], Forgie, Ian M [0000-0002-8800-6145], Allin, Kristine H [0000-0002-6880-5759], Hansen, Tue H [0000-0001-5948-8993], Elders, Petra JM [0000-0002-5907-7219], Häussler, Ragna S [0000-0003-1664-8875], 't Hart, Leen M [0000-0003-4401-2938], Hattersley, Andrew T [0000-0001-5620-473X], Schwenk, Jochen M [0000-0001-8141-8449], McCarthy, Mark I [0000-0002-4393-0510], Pearson, Ewan R [0000-0001-9237-8585], Bell, Jimmy D [0000-0003-3804-1281], Franks, Paul W [0000-0002-0520-7604], IMI

المصدر: PLoS Medicine, 17(6):e1003149. Public Library of Science
PLoS Medicine
Atabaki-Pasdar, N, Ohlsson, M, Viñuela, A, Frau, F, Pomares-Millan, H, Haid, M, Jones, A G, Louise Thomas, E, Koivula, R W, Kurbasic, A, Mutie, P M, Fitipaldi, H, Fernandez, J, Dawed, A Y, Giordano, G N, Forgie, I M, McDonald, T J, Rutters, F, Cederberg, H, Chabanova, E, Dale, M, de Masi, F, Thomas, C E, Allin, K H, Hansen, T H, Heggie, A, Hong, M G, Elders, P J M, Kennedy, G, Kokkola, T, Pedersen, H K, Mahajan, A, McEvoy, D, Pattou, F, Raverdy, V, Häussler, R S, Sharma, S, Thomsen, H S, Vangipurapu, J, Vestergaard, H, T Hart, L M, Adamski, J, Musholt, P B, Brage, S, Brunak, S, Dermitzakis, E, Frost, G, Hansen, T, Laakso, M, Pedersen, O, Ridderstråle, M, Ruetten, H, Hattersley, A T, Walker, M, Beulens, J W J, Mari, A, Schwenk, J M, Gupta, R, McCarthy, M I, Pearson, E R, Bell, J D, Pavo, I & Franks, P W 2020, ' Predicting and elucidating the etiology of fatty liver disease : A machine learning modeling and validation study in the IMI DIRECT cohorts ', PLoS Medicine, vol. 17, no. 6, e1003149 . https://doi.org/10.1371/journal.pmed.1003149Test
Atabaki-Pasdar, N, Ohlsson, M, Viñuela, A, Frau, F, Pomares-Millan, H, Haid, M, Jones, A G, Thomas, E L, Koivula, R W, Kurbasic, A, Mutie, P M, Fitipaldi, H, Fernandez, J, Dawed, A Y, Giordano, G N, Forgie, I M, McDonald, T J, Rutters, F, Cederberg, H, Chabanova, E, Dale, M, Masi, F D, Thomas, C E, Allin, K H, Hansen, T H, Heggie, A, Hong, M G, Elders, P J M, Kennedy, G, Kokkola, T, Pedersen, H K, Mahajan, A, McEvoy, D, Pattou, F, Raverdy, V, Häussler, R S, Sharma, S, Thomsen, H S, Vangipurapu, J, Vestergaard, H, 't Hart, L M, Adamski, J, Musholt, P B, Brage, S, Brunak, S, Dermitzakis, E, Frost, G, Hansen, T, Laakso, M, Pedersen, O, Ridderstråle, M, Ruetten, H, Hattersley, A T, Walker, M, Beulens, J W J, Mari, A, Schwenk, J M, Gupta, R, McCarthy, M I, Pearson, E R, Bell, J D, Pavo, I & Franks, P W 2020, ' Predicting and elucidating the etiology of fatty liver disease : A machine learning modeling and validation study in the IMI DIRECT cohorts ', PLoS Medicine, vol. 17, no. 6, pp. e1003149 . https://doi.org/10.1371/journal.pmed.1003149Test
PLoS Medicine, Vol 17, Iss 6, p e1003149 (2020)
PLoS Medicine, 17(6). PUBLIC LIBRARY SCIENCE

مصطلحات موضوعية: Male, Proteomics, Oral Glucose Suppression Test, Biochemistry, Machine Learning, Fats, Database and Informatics Methods, Endocrinology, Medicine and Health Sciences, Insulin, Prospective Studies, 11 Medical and Health Sciences, GLOBAL EPIDEMIOLOGY, INSULIN SENSITIVITY, Proteomic Databases, Liver Diseases, Middle Aged, Lipids, Medicine, Female, Life Sciences & Biomedicine, Research Article, Computer and Information Sciences, Endocrine Disorders, BIOMARKERS, Gastroenterology and Hepatology, Research and Analysis Methods, Risk Assessment, Diabetes Complications, Medicine, General & Internal, SDG 3 - Good Health and Well-being, Artificial Intelligence, General & Internal Medicine, NAFLD, Diabetes Mellitus, Humans, Metabolomics, Diabetic Endocrinology, Pharmacology, Science & Technology, Models, Statistical, Reproducibility of Results, Biology and Life Sciences, ALCOHOLIC STEATOHEPATITIS, Hormones, Pharmacologic-Based Diagnostics, Fatty Liver, Metabolism, Biological Databases, 3121 General medicine, internal medicine and other clinical medicine, Metabolic Disorders

وصف الملف: application/pdf; text/xml; application/zip

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1bc926a99b5302cc30d7245d0440117Test
https://research.vumc.nl/en/publications/f7988584-4096-47b4-b939-809f82641881Test