دورية أكاديمية
Transcranial magnetic stimulation in autism spectrum disorder: Challenges, promise, and roadmap for future research
| العنوان: | Transcranial magnetic stimulation in autism spectrum disorder: Challenges, promise, and roadmap for future research |
|---|---|
| المؤلفون: | LM Oberman, Peter Enticott, MF Casanova, A Rotenberg, A Pascual-Leone, JT Mccracken, S Ameis, D Brock, M Demitrack, P Croarkin, G Dawson, W Wu, D Gilbert, E Hollander, M Iacoboni, K Lim, S Mostofsky, E Pedapati, S Swedo, KH Taylor, P Wang, C Wall |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Clinical sciences not elsewhere classified, Neurosciences not elsewhere classified, Other psychology not elsewhere classified, Science & Technology, Social Sciences, Life Sciences & Biomedicine, Behavioral Sciences, Psychology, Developmental, autism spectrum disorder, transcranial magnetic stimulation, consensus, review, treatment, HUMAN MOTOR CORTEX, NONINVASIVE BRAIN-STIMULATION, NOREPINEPHRINE-REUPTAKE INHIBITOR, THETA-BURST STIMULATION, HIGH-FUNCTIONING AUTISM, LONG-TERM POTENTIATION, CORTICAL INHIBITION, INTRACORTICAL INHIBITION, SYNAPTIC PLASTICITY, ALZHEIMERS-DISEASE, 170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology), 110903 Central Nervous System, 110319 Psychiatry (incl Psychotherapy), 920410 Mental Health |
| الوصف: | Autism Spectrum Disorder (ASD) is a behaviorally defined complex neurodevelopmental syndrome characterized by impairments in social communication, by the presence of restricted and repetitive behaviors, interests and activities, and by abnormalities in sensory reactivity. Transcranial magnetic stimulation (TMS) is a promising, emerging tool for the study and potential treatment of ASD. Recent studies suggest that TMS measures provide rapid and noninvasive pathophysiological ASD biomarkers. Furthermore, repetitive TMS (rTMS) may represent a novel treatment strategy for reducing some of the core and associated ASD symptoms. However, the available literature on the TMS use in ASD is preliminary, composed of studies with methodological limitations. Thus, off-label clinical rTMS use for therapeutic interventions in ASD without an investigational device exemption and outside of an IRB approved research trial is premature pending further, adequately powered and controlled trials. Leaders in this field have gathered annually for a two-day conference (prior to the 2014 and 2015 International Meeting for Autism Research, IMFAR) to share recent progress, promote collaboration across laboratories, and establish consensus on protocols. Here we review the literature in the use of TMS in ASD in the context of the unique challenges required for the study and exploration of treatment strategies in this population. We also suggest future directions for this field of investigations. While its true potential in ASD has yet to be delineated, TMS represents an innovative research tool and a novel, possibly transformative approach to the treatment of neurodevelopmental disorders. Autism Res 2015. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | http://hdl.handle.net/10536/DRO/DU:30079689Test; https://figshare.com/articles/journal_contribution/Transcranial_magnetic_stimulation_in_autism_spectrum_disorder_Challenges_promise_and_roadmap_for_future_research/20895844Test |
| الإتاحة: | http://hdl.handle.net/10536/DRO/DU:30079689Test https://figshare.com/articles/journal_contribution/Transcranial_magnetic_stimulation_in_autism_spectrum_disorder_Challenges_promise_and_roadmap_for_future_research/20895844Test |
| حقوق: | All Rights Reserved |
| رقم الانضمام: | edsbas.347D74FA |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |