دورية أكاديمية
Evidence synthesis and guideline development in genomic medicine: current status and future prospects
| العنوان: | Evidence synthesis and guideline development in genomic medicine: current status and future prospects |
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| المؤلفون: | Boccia, Stefania |
| المساهمون: | Schully, Sd, Lam, Tk, Dotson, Wd, Chang, Cq, Aronson, N, Birkeland, Ml, Brewster, Sj, Boccia, Stefania, Buchanan, Ah, Calonge, N, Calzone, K, Djulbegovic, B, Goddard, Ka, Klein, Rd, Klein, Te, Lau, J, Long, R, Lyman, Gh, Morgan, Rl, Palmer, Cg, Relling, Mv, Rubinstein, W, Swen, Jj, Terry, Sf, Williams, M, Khoury, Mj |
| سنة النشر: | 2015 |
| المجموعة: | Università Cattolica del Sacro Cuore: PubliCatt |
| مصطلحات موضوعية: | evidence synthesis, genomic medicine, guideline, development, Settore MED/42 - IGIENE GENERALE E APPLICATA |
| الوصف: | Purpose:With the accelerated implementation of genomic medicine, health-care providers will depend heavily on professional guidelines and recommendations. Because genomics affects many diseases across the life span, no single professional group covers the entirety of this rapidly developing field.Methods:To pursue a discussion of the minimal elements needed to develop evidence-based guidelines in genomics, the Centers for Disease Control and Prevention and the National Cancer Institute jointly held a workshop to engage representatives from 35 organizations with interest in genomics (13 of which make recommendations). The workshop explored methods used in evidence synthesis and guideline development and initiated a dialogue to compare these methods and to assess whether they are consistent with the Institute of Medicine report "Clinical Practice Guidelines We Can Trust." Results:The participating organizations that develop guidelines or recommendations all had policies to manage guideline development and group membership, and processes to address conflicts of interests. However, there was wide variation in the reliance on external reviews, regular updating of recommendations, and use of systematic reviews to assess the strength of scientific evidence. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/24946156; info:eu-repo/semantics/altIdentifier/wos/WOS:000347744900010; volume:17; issue:1; firstpage:63; lastpage:67; issueyear:2014; journal:GENETICS IN MEDICINE; http://hdl.handle.net/10807/61230Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84920546044 |
| DOI: | 10.1038/gim.2014.69 |
| الإتاحة: | https://doi.org/10.1038/gim.2014.69Test http://hdl.handle.net/10807/61230Test |
| رقم الانضمام: | edsbas.9EB4943E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/gim.2014.69 |
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