دورية أكاديمية

The cost of hospitalizations for treatment of hemodialysis catheter-associated blood stream infections in children: a retrospective cohort study.

التفاصيل البيبلوغرافية
العنوان: The cost of hospitalizations for treatment of hemodialysis catheter-associated blood stream infections in children: a retrospective cohort study.
المؤلفون: Wasik, Heather L., Neu, Alicia, Warady, Bradley, Crawford, Brendan, Richardson, Troy, De Souza, Heidi G., Cardwell, Diana, Ruebner, Rebecca
المصدر: Pediatric Nephrology; Jun2023, Vol. 38 Issue 6, p1915-1923, 9p, 1 Diagram, 4 Charts, 1 Graph
مصطلحات موضوعية: LENGTH of stay in hospitals, INTENSIVE care units, CATHETER-related infections, CONFIDENCE intervals, MEDICAL care costs, RETROSPECTIVE studies, ACQUISITION of data, REGRESSION analysis, HOSPITAL care, MEDICAL records, DESCRIPTIVE statistics, HEMODIALYSIS, CENTRAL venous catheters, BLOODBORNE infections, LONGITUDINAL method, CHILDREN, ADOLESCENCE
مستخلص: Background: Hospitalization costs for treatment of hemodialysis (HD) catheter-associated blood stream infections (CA-BSI) in adults are high. No studies have evaluated hospitalization costs for HD CA-BSI in children or identified factors associated with high-cost hospitalizations. Methods: We analyzed 160 HD CA-BSIs from the Standardizing Care to Improve Outcomes in Pediatric End-stage Kidney Disease (SCOPE) collaborative database linked to hospitalization encounters in the Pediatric Health Information System (PHIS) database. Charge-to-cost ratios were used to convert hospitalization charges reported in PHIS database to estimated hospital costs. Generalized linear mixed modeling was used to assess the relationship between higher-cost hospitalization (cost above 50th percentile) and patient and clinical characteristics. Generalized linear regression models were used to assess differences in mean service line costs between higher- and lower-cost hospitalizations. Results: The median (IQR) length of stay for HD CA-BSI hospitalization was 5 (3–10) days. The median (IQR) cost for HD CA-BSI hospitalization was $18,375 ($11,584–$36,266). ICU stay (aOR 5.44, 95% CI 1.62–18.26, p = 0.01) and need for a catheter procedure (aOR = 6.08, 95% CI 2.45–15.07, p < 0.001) were associated with higher-cost hospitalization. Conclusions: Hospitalizations for HD CA-BSIs in children are often multiple days and are associated with substantial costs. Interventions to reduce CA-BSI may reduce hospitalization costs for children who receive chronic HD. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:0931041X
DOI:10.1007/s00467-022-05764-2