المؤلفون: Heisey, Henry D., Qualls, Clifford, Villareal, Dennis T., Segoviano-Escobar, Martha Belen, Nava, Maria Liza Duremdes, Gatchel, Jennifer R., Kunik, Mark E.

المصدر: Journal of Geriatric Psychiatry & Neurology; Jul2024, Vol. 37 Issue 4, p332-338, 7p

مصطلحات موضوعية: OLDER people, MENTAL depression, C-reactive protein, DEPRESSION in men, ANTIDEPRESSANTS, COMPULSIVE eating

مستخلص: Objectives: To test the hypothesis that depressive symptoms vary with high-sensitivity C-reactive protein (hs-CRP), among older adults with obesity. Methods: This was a cross-sectional, secondary analysis of baseline data from two related lifestyle intervention trials. The study sample comprises 148 consecutively recruited, community-dwelling older adults (age >=65 years) without severe psychiatric illness and with body mass index >=30 kg/m². Logarithmically transformed GDS was analyzed as the dependent variable. Independent variables included log-transformed hs-CRP and covariates: sex, age, and concurrent use of antidepressant medication at baseline. An additional analysis was performed using binary conversion of the GDS scores, wherein a cutoff score of 5 was considered positive for depressive symptoms. Results: Sample mean GDS score was 2.7 (SD 3.0, range 0 – 14). A significant multivariate model of GDS scores (R² =.089, F = 3.5, P =.010) revealed log-transformed hs-CRP (P =.017) and male sex (P =.012) as associated with depressive symptoms. Supplemental analysis demonstrated associations between depressive symptoms and log-transformed hs-CRP (OR 2.17, P =.001) and between depressive symptoms and male sex (OR 3.78, P =.013). Univariate logistic regression found hs-CRP to be associated with depressive symptoms. Conclusions: In older adults with obese BMI, male sex and higher hs-CRP are associated with depression, even in a group with relatively minimal depressive symptoms. Hs-CRP may offer clinical utility as a biomarker for depression among older adults with obese BMI, even among those with non-severe psychiatric symptomatology. [ABSTRACT FROM AUTHOR]

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المؤلفون: Griffiths, Kristi R., Boulet, Stephanie, Barakat, Sarah, Touyz, Stephen, Hay, Phillipa, Maguire, Sarah, Kohn, Michael R.

المصدر: Journal of Eating Disorders; 6/13/2024, Vol. 12 Issue 1, p1-12, 12p

مصطلحات موضوعية: BINGE-eating disorder, QUALITY of life, BULIMIA, EATING disorders, MENTAL illness, COMPULSIVE eating

مصطلحات جغرافية: NEW Zealand

مستخلص: Background: Lisdexamfetamine dimesylate (LDX) has demonstrated safety and efficacy for treatment of Binge Eating Disorder (BED). However, to date, trials have not included participants with co-occurring psychiatric disorders. This study explores how LDX affects eating disorder psychopathology, symptoms of common psychiatric comorbidities of BED (ADHD, depression, anxiety), and psychological quality of life, in people with moderate to severe BED. Methods: These are secondary analyses of an open-label LDX trial conducted in 41 adults (18–40 years) over eight-weeks. Participants received LDX titrated to 50 or 70 mg. Clinical assessments and self-report questionnaires were conducted at baseline and 8-week follow-up. Results: Eating disorder psychopathology and psychological quality of life improved after 8-weeks of LDX. No significant group-level changes in depression, anxiety or ADHD severity scores were observed. However, the majority within the small subsets with elevated depression and ADHD symptoms experienced reduced depressive and inattentive symptom severity, respectively. Conclusions: We provide proof-of-concept evidence that LDX may provide broader psychological benefits to individuals with BED, beyond reducing their BE frequency. Effects of LDX on anxiety should be monitored closely by clinicians. Early indications suggest that LDX may be effectively used in people with BED, with and without co-occurring psychiatric conditions, however tolerability may be lower in highly complex cases. Trial registration: Australian and New Zealand Clinical Trials Registry (anzctr.org.au) #ACTRN12618000623291. Plain English summary: Lisdexamfetamine dimesylate (LDX) has been shown to reduce binge eating frequency among those with Binge Eating Disorder (BED). However, little is known about how LDX affects symptoms of common co-occurring conditions (ADHD, depression, anxiety) and mental health more broadly. In this study, 41 people with BED received an 8-week course of LDX and their symptoms were monitored before and after treatment. Overall, people experienced a robust improvement in eating disorder psychopathology and psychological quality of life. For those with higher levels of depression and ADHD, LDX had the additional benefit of improving depressive symptoms and inattentive symptom severity, respectively. The effect of LDX on anxiety symptoms appears to be more complex, with an equal proportion of people experiencing a decrease or an increase in anxiety over the course of treatment. Those who experienced reductions in anxiety during treatment tended to have greater concurrent reductions in binge eating frequency. This study provides preliminary evidence that for people with BED, LDX may be effective at improving co-occurring symptoms of eating disorder psychopathology and psychological well-being, and potentially ADHD and depression symptoms when present at an elevated level. More research is needed among a larger sample to verify these findings. [ABSTRACT FROM AUTHOR]

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المؤلفون: Kocol, Dilara, Bäuerle, Alexander, Schadendorf, Theresa, Geiger, Sheila, Krakowczyk, Julia Barbara, Skoda, Eva-Maria, Teufel, Martin

المصدر: Frontiers in Psychiatry; 2024, p1-12, 12p

مصطلحات موضوعية: BULIMIA, MENTAL depression, COMPULSIVE eating, RANDOMIZED controlled trials, PHYSICIANS, BINGE-eating disorder, EATING disorders

مستخلص: Introduction: Obesity and depression are inter-related health concerns, demanding a high level of treatment and costs in the health care system. The development of eHealth interventions that simultaneously address obesity and mental health can be supportive in this regard. However, evidence of the efficacy of eHealth interventions in the treatment of depression symptoms in individuals with obesity is lacking. The aim of this systematic literature review is to evaluate the efficacy of existing eHealth interventions for individuals with obesity that target depression symptoms. Methods: We systematically searched electronic databases (Cochrane Library, PubMed, Scopus) to identify studies published in English between January 2016 and January 2023, that focused on eHealth interventions, targeting depression symptoms in individuals with obesity people. Exclusion criteria were study objectives that (1) focused specifically on one or more metabolic comorbidities of individuals with obesity, e.g., hypertension, hyperlipidemia, diabetes; (2) focused specifically on eating disorders comorbidities e.g., binge eating disorder, and (3) focused specifically on patients before or after bariatric surgery. Results: The database search identified 214 records. Six articles were included i this review. Sample sizes ranged from 70 to 1267 participants of ages 18-60 years. All included studies were randomized controlled trials. Two of the six included studies were web-based interventions guided either by medical doctors or psychologists. All interventions included video, printed materials, and interactive parts of which two studies integrated elements of Cognitive Behavioural Therapy and Social Cognitive Therapy. The findings showed that eHealth treatment services, supported and guided throughout the intervention had high acceptance and efficacy in the reduction of depression symptoms among individuals with obesity. Conclusion: EHealth interventions that address and target both mental and physical health with interactive strategies calls for better efficacy in the reduction of depression symptoms. Future eHealth interventions that target depression symptoms in individuals with obesity should integrate digital strategies that address both mental and physical health through interactive modules. [ABSTRACT FROM AUTHOR]

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المؤلفون: Yunyi Zhu, Yuan Yin, Fei Huang, Yuanjun Liu, Yuge Xia, Mingying Zhang, Yunhe Wang, Lijuan Jin

المصدر: European Psychiatry; 2024, Vol. 67 Issue 1, p1-7, 7p

مصطلحات موضوعية: BODY mass index, MENTAL depression, OBESITY, MENTAL health, BODY weight, UNHEALTHY lifestyles, COMPULSIVE eating

مستخلص: Background. The association between obesity and depression may partly depend on the contextual metabolic health. The effect of change in metabolic health status over time on subsequent depression risk remains unclear. We aimed to assess the prospective association between metabolic health and its change over time and the risk of depression across body mass index (BMI) categories. Methods. Based on a nationally representative cohort, we included participants enrolled at the wave 2 (2004-2005) of the English Longitudinal Study of Ageing andwith follow-up for depression at wave 8 (2016-2017). Participants were cross-classified by BMI categories and metabolic health (defined by the absence of hypertension, diabetes, and hypercholesterolemia) at baseline or its change over time (during waves 3-6). Logistic regression model was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for the risk of depression at follow-up stratified by BMI category and metabolic health status with adjustment for potential confounders. Results. The risk of depression was increased for participants with metabolically healthy obesity compared with healthy nonobese participants, and the risk was highest for those with metabolically unhealthy obesity (OR 1.62, 95% CI 1.18-2.20). Particularly hypertension and diabetes contribute most to the increased risk. The majority of metabolically healthy participants converted to unhealthy metabolic phenotype (50.1% of those with obesity over 8 years), which was associated with an increased risk of depression. Participants who maintained metabolically healthy obesity were still at higher risk (1.99, 1.33-2.72), with the highest risk observed for those with stable unhealthy metabolic phenotypes. Conclusions. Obesity remains a risk factor for depression, independent of whether other metabolic risk factors are present or whether participants convert to unhealthy metabolic phenotypes over time. Long-term maintenance of metabolic health and healthy body weight may be beneficial for the population mental well-being. [ABSTRACT FROM AUTHOR]

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المؤلفون: Skinner, Janelle A.^1,2 (AUTHOR), Leary, Mark^1,2 (AUTHOR), Whatnall, Megan^1,2 (AUTHOR), Collins, Rebecca A.^1,2 (AUTHOR), Pursey, Kirrilly M.^1,2 (AUTHOR), Verdejo-Garcia, Antonio³ (AUTHOR), Hay, Phillipa J.^4,5 (AUTHOR), Baker, Amanda L.^2,6 (AUTHOR), Hides, Leanne⁷ (AUTHOR), Paxton, Susan J.⁸ (AUTHOR), Wood, Lisa G.^2,9 (AUTHOR), Colyvas, Kim¹ (AUTHOR), Collins, Clare E.^1,2 (AUTHOR), Burrows, Tracy L.^1,2 (AUTHOR) tracy.burrows@newcastle.edu.au

المصدر: Appetite. Apr2024, Vol. 195, pN.PAG-N.PAG. 1p.

مصطلحات موضوعية: *COMPULSIVE eating, *RANDOMIZED controlled trials, *AUSTRALIANS, *MENTAL illness, *INGESTION, *TELEMEDICINE

مستخلص: There is a substantial research base for addictive eating with development of interventions. The current 3-arm RCT aimed to investigate the efficacy of the TRACE (Targeted Research for Addictive and Compulsive Eating) program to decrease addictive eating symptoms and improve mental health. Participants (18-85 yrs) endorsing ≥3 addictive eating symptoms were randomly allocated to 1) active intervention, 2) passive intervention, or 3) control group. Primary outcome was change in addictive eating symptoms 3-months post-baseline measured by the Yale Food Addiction Scale. Depression, anxiety and stress were also assessed. A total of 175 individuals were randomised. Using Linear Mixed Models, from baseline to 3-months, there was significant improvement in symptom scores in all groups with mean decrease of 4.7 (95% CI: −5.8, −3.6; p < 0.001), 3.8 (95% CI: −5.2, −2.4; p < 0.001) and 1.5 (95% CI: −2.6, −0.4; p = 0.01) respectively. Compared with the control group, participants in the active intervention were five times more likely to achieve a clinically significant change in symptom scores. There was a significant reduction in depression scores in the active and passive intervention groups, but not control group [-2.9 (95% CI: −4.5, −1.3); −2.3 (95% CI: −4.3, −0.3); 0.5 (95% CI: −1.1, 2.1), respectively]; a significant reduction in stress scores within the active group, but not passive intervention or control groups [-1.3 (95% CI: −2.2, −0.5); −1.0 (95% CI: −2.1, 0.1); 0.4 (95% CI: −0.5, 1.2), respectively]; and the reduction in anxiety scores over time was similar for all groups. A dietitian-led telehealth intervention for addictive eating in adults was more effective than a passive or control condition in reducing addictive eating scores from baseline to 6 months. Trial registration: Australia New Zealand Clinical Trial Registry ACTRN12621001079831. [ABSTRACT FROM AUTHOR]

المؤلفون: Dashputre, Anushka, Agho, Kingsley E., Piya, Milan K., Glenister, Kristen, Bourke, Lisa, Hannah, Stephanie, Bhat, Ravi, Osuagwu, Uchechukwu L., Simmons, David

المصدر: BMC Psychiatry; 6/20/2023, Vol. 23 Issue 1, p1-14, 14p, 3 Charts

مصطلحات موضوعية: MENTAL illness, PSYCHOLOGICAL distress, MENTAL depression, CROSS-sectional method, MENTAL health, COMPULSIVE eating

مصطلحات جغرافية: VICTORIA, AUSTRALIA

مستخلص: Background: Research suggests that rates of mental illness are similar in rural and urban Australia, although there are significant workforce shortages in rural regions along with higher rates of chronic disease and obesity and lower levels of socioeconomic status. However, there are variations across rural Australia and limited local data on mental health prevalence, risk, service use and protective factors. This study describes the prevalence of self-reported mental health problems of psychological distress and depression, in a rural region in Australia and aims to identify the factors associated with these problems. Methods: The Crossroads II study was a large-scale cross-sectional study undertaken in the Goulburn Valley region of Victoria, Australia in 2016–18. Data were collected from randomly selected households across four rural and regional towns and then screening clinics from individuals from these households. The main outcome measures were self-reported mental health problems of psychological distress assessed by the Kessler 10 and depression assessed by Patient Health Questionnaire-9. Unadjusted odd ratios and 95% confidence intervals of factors associated with the two mental health problems were calculated using simple logistic regression with multiple logistic regression using hierarchical modelling to adjust for the potential confounders. Results: Of the 741 adult participants (55.6% females), 67.4% were aged ≥ 55 years. Based on the questionnaires, 16.2% and 13.6% had threshold-level psychological distress and depression, respectively. Of those with threshold-level K-10 scores, 19.0% and 10.5% had seen a psychologist or a psychiatrist respectively while 24.2% and 9.5% of those experiencing depression had seen a psychologist or a psychiatrist, respectively in the past year. Factors such as being unmarried, current smoker, obesity, were significantly associated with a higher prevalence of mental health problems whereas physical activity, and community participation reduced the risk of mental health problems. Compared to rural towns, the regional town had higher risk of depression which was non-significant after adjusting for community participation and health conditions. Conclusions: The high prevalence of psychological distress and depression in this rural population was consistent with other rural studies. Personal and lifestyle factors were more relevant to mental health problems than degree of rurality in Victoria. Targeted lifestyle interventions could assist in reducing mental illness risk and preventing further distress. [ABSTRACT FROM AUTHOR]

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المؤلفون: Sackett, Marilyn, Clark, Kevin R., Webster, Tammy L.

المصدر: Radiologic Technology; Jan/Feb2023, Vol. 94 Issue 3, p168-179, 12p, 11 Charts

مصطلحات موضوعية: COMPETENCY assessment (Law), SHIFT systems, PRAYER, STATISTICS, KRUSKAL-Wallis Test, RESPIRATORY muscles, MEDITATION, SOCIAL support, SPIRITUALITY, CONFIDENCE intervals, MASSAGE therapy, COMPULSIVE eating, CROSS-sectional method, RADIOLOGIC technologists, SOCIAL stigma, SURVEYS, EMPLOYEE assistance programs, CRONBACH'S alpha, PSYCHOSOCIAL factors, MENTAL depression, QUESTIONNAIRES, SCALE analysis (Psychology), DESCRIPTIVE statistics, CHI-squared test, ALCOHOL drinking, PSYCHOLOGICAL adaptation, ANXIETY, JOB performance, STATISTICAL sampling, RESPIRATION, SMOKING

مصطلحات جغرافية: TEXAS

مستخلص: Purpose To determine the relationships between mental health (depression and anxiety) and engaging in shift work, working weekend shifts, and taking call for radiologic technologists, and to identify coping strategies used to manage depression and anxiety. Methods Validated instruments were used to measure depression and anxiety levels among a sample of radiologic technologists who were members of Advanced Health Education Center. The participants also identified their primary work shift and their frequency of working weekends and taking call. Results There were 173 completed survey responses for this study. Most radiologic technologists in this study experienced mild symptoms of depression (62, 35.8%) and anxiety (57, 32.9%). Nearly half of the participants indicated that their depression and anxiety made it difficult for them to perform their jobs effectively, and about one-third of the participants believed those symptoms were intensified by shift work. A strong, positive relationship was identified between participants' total depression and anxiety scores (P < .001). There were no significant differences between shift work and total depression score (P = .06) or total anxiety score (P = .28). A significant association was found between the frequency of working weekend shifts and depression levels (P < .001) with a moderate effect size. Most of the participants identified support from family or friends, prayer and spiritual activities, and prescribed medication as common coping strategies. Discussion Findings revealed that the radiologic technologists in this study did not rely heavily on employer-based resources, such as employee assistance programs, to cope with their depression and anxiety symptoms. One speculation for underuse of these employer-based resources might be fear of being stigmatized by management or personal perceived stigma against asking for help. There is an opportunity for increased awareness of available mental health resources and acceptance of mental health management to erase the common, negative stigma associated with seeking out professional resources. Conclusion Radiologic technologists in this study experienced depression and anxiety symptoms that affected their work performance and correlated with working weekend shifts; however, there was no significant relationship between shift work and depression or anxiety in this sample of radiologic technologists. [ABSTRACT FROM AUTHOR]

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المؤلفون: Berkowitz, Seth A., Palakshappa, Deepak, Seligman, Hilary K., Hanmer, Janel

المصدر: JGIM: Journal of General Internal Medicine; Nov2022, Vol. 37 Issue 14, p3638-3644, 7p, 2 Charts, 1 Graph

مصطلحات موضوعية: FOOD security, QUALITY of life, COHORT analysis, PSYCHOLOGICAL distress, RACE, COMPULSIVE eating

مستخلص: Background: Cross-sectional studies have found that health-related quality of life and mental health are worse among food-insecure compared with food-secure individuals. However, how these outcomes change as food insecurity changes is unclear. Objective: To evaluate how common patient-reported health-related quality of life and mental health scales change in response to changes in food security. Design: Retrospective cohort study using data representative of the civilian, adult, non-institutionalized population of the USA. Participants: Food insecure adults who completed the 2016–2017 Medical Expenditure Panel Survey. Main Measures: Mental health, as measured by the mental component score of the Veterans Rand 12-Item Health Survey (VR-12) (primary outcome), along physical health (physical component score of the VR-12), self-rated health status, psychological distress (Kessler 6), depressive symptoms (PHQ2), and the SF-6D measure of health utility. We fit linear regression models adjusted for baseline outcome level, age, gender, race/ethnicity, education, health insurance, and family size followed by predictive margins to estimate the change in outcome associated with a 1-point improvement in food security. Key Results: A total of 1,390 food-insecure adults were included. A 1-point improvement in food security was associated with a 0.38 (95%CI 0.62 to 0.14)-point improvement in mental health, a 0.15 (95%CI 0.02 to 0.27)-point improvement in psychological distress, a 0.05 (95%CI 0.01 to 0.09)-point improvement in depressive symptoms, and a 0.003 (95%CI 0.000 to 0.007)-point improvement in health utility. Point estimates for physical health and self-rated health were in the direction of improvement, but were not statistically significant. Conclusions: Improvement in food insecurity was associated with improvement in several patient-reported outcomes. Further work should investigate whether similar changes are seen in food insecurity interventions, and the most useful scales for assessing changes in health-related quality of life and mental health in food insecurity interventions. [ABSTRACT FROM AUTHOR]

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المؤلفون: Tabone, Jiyoung K., Cox, Stephanie, Aylward, Laura, Abunnaja, Salim, Szoka, Nova, Tabone, Lawrence E.

المصدر: Obesity Surgery; Sep2022, Vol. 32 Issue 9, p3034-3040, 7p

مصطلحات موضوعية: ADVERSE childhood experiences, BINGE-eating disorder, COMPULSIVE eating, BULIMIA, OBESITY, MENTAL health, PREOPERATIVE period

مستخلص: Objective: Research has demonstrated that adverse childhood experiences (ACEs) were related to elevated lifetime risk of developing obesity, but the underlying mechanisms between ACEs and development of obesity are yet to be fully elucidated. The current study aims to extend exiting evidence on underlying mechanisms between ACEs and development of obesity by examining whether depressive symptom and binge eating symptom have independently significant mediating effects on the association. Methods: The study used data from a total of 473 patients seeking bariatric surgery who completed psychological evaluation including ACEs, depressive symptom, and binge eating scale as a part of presurgical multidisciplinary weight management consultations. Mediation analyses were conducted using the PROCESS macro for SPSS to examine the research objective. Results: The study found that depressive symptom uniquely mediated the relationship between ACEs and obesity, but binge eating symptom did not significantly mediate the relationship independently of depression. Conclusions: The unique role of depression in relation to childhood trauma in this study argues for more focus on a mental health intervention with bariatric patients during the preoperative period. Addressing ACEs for bariatric patients who present psychiatric symptoms during preoperative process could have potential benefits to patient care. [ABSTRACT FROM AUTHOR]

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المؤلفون: Rasaei, Niloufar, Ghaffarian-Ensaf, Rasool, Shiraseb, Farideh, Abaj, Faezeh, Gholami, Fatemeh, Clark, Cain C. T., Mirzaei, Khadijeh

المصدر: BMC Women's Health; 7/15/2022, Vol. 22 Issue 1, p1-11, 11p

مصطلحات موضوعية: OVERWEIGHT women, BEVERAGE consumption, CROSS-sectional method, COMPULSIVE eating, ESTIMATION theory, MENTAL health, OBESITY, BEVERAGES, DIET, HEALTH status indicators, MENTAL depression, QUESTIONNAIRES

مصطلحات جغرافية: TEHRAN (Iran), IRAN

مستخلص: Background and Aims: The Healthy Beverage Index (HBI) is a valuable technique to estimate the synergistic effects of overall beverage consumption. Several studies have evaluated the associations between HBI and beneficial changes in the health status. however, there is no study on the association between patterns of beverage consumption and mental health status. Therefore, this study sought to examine the association between HBI and psychological disorders among overweight and obese women.Methods: 199 overweight and obese women, between the ages of 18 and 55 y, were enrolled in this cross-sectional study in Tehran, Iran. To collect beverage dietary data, a validated semi-quantitative food-frequency questionnaire (FFQ) was used. Furthermore, the DASS-21 questionnaire was used to assess psychological profile states.Results: The association of total depression anxiety stress (DASS) score with healthy beverage index (HBI) tertiles in models was marginally significant (OR =: 0.78; 95% CI 0.30-2.02; P-value = 0.074; (OR = 0.77; 95% CI 0.28-2.16; P-value = 0.062), respectively. In terms of stress, anxiety, and depression, after adjusting for confounders, participants with higher HBI in the third tertile had lower odds of depression vs. the first tertile (OR = 0.99; 95% CI 0.35-2.81; P-trend = 0.040).Conclusion: We demonstrate that the total DASS score was associated with HBI tertiles. We also found that participants with higher HBI had lower odds of depression. However, additional well-designed studies are needed to confirm the veracity of these findings. [ABSTRACT FROM AUTHOR]

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