المؤلفون: Fiston Mbutiwi Ikwa, Ndol, François Lepira, Bompeka, Michèle, Dramaix-Wilmet, Philippe, Meert, Myriam, Malengreau, Nazaire Nseka, Mangani, Flory Muanda, Tsobo, Dramane, Koné

المصدر: Sante publique (Vandoeuvre-les-Nancy, France). 25(2)

مصطلحات موضوعية: Adult, Aged, 80 and over, Male, Adolescent, Self Medication, Middle Aged, Young Adult, Cross-Sectional Studies, Patient Admission, Democratic Republic of the Congo, Prevalence, Humans, Female, Emergency Service, Hospital, Aged

الوصف: A cross-sectional descriptive study was conducted at Kinshasa University Hospital (KUH) to determine the prevalence of self-medication among patients admitted to KUH and to identify commonly used drugs. 391 patients aged 14 to 92 years admitted to the KUH emergency department between 15 January and 15 February 2011 were included in the study. 233 patients out of a total of 391 (59.6%) used self-medication between the onset of symptoms and the visit to KUH. The number of drugs used ranged from 1 to 7. Of the 233 patients who practiced self-medication, 224 (96.1%) used pharmaceutical drugs alone, 4 (1.7%) used traditional African remedies alone, 1 (0.4%) used Chinese medicine alone, and 4 (1.7%) combined pharmaceutical drugs with traditional African remedies. Analgesics and antipyretics (44.3%), non-steroidal anti-inflammatory drugs (NSAIDs) (26.3%), antimalarials (20.6%) and antibacterials (12.3%) were the most commonly used pharmaceutical drugs. Paracetamol was the most commonly used analgesic and antipyretic (89.1%). Among NSAIDs, diclofenac (65%) was the most widely used. Artemisinin-based combination drugs (40.4%) were the most commonly used antimalarials, with lumefantrine being the most common. The most widely reported antibacterials were betalactam antibiotics (ampicillin and amoxicillin) (42.9%). The results show that self-medication, based mainly on commonly prescribed pharmaceutical drugs, appears to be a common therapeutic option before seeking hospital care and may be a major threat to individual and community health.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::642143929f7471b28c1eb7118c138286Test
https://pubmed.ncbi.nlm.nih.gov/23964549Test

المؤلفون: Rissassi, Makulo, Mangani Nazaire, Nseka, Michel, Jadoul, Moise, Mvitu, Muel Telo, Muyer, Wivine, Kimenyembo, Makasa, Mandja, Ebanz'Osongo, Bieleli, Mala Ali, Mapatano, François Bompeka, Epira, Ernest Kiswaya, Sumaili, W K, Kaimbo, Okwe, Nge, Frank, Buntinx, Erik, Muls

المصدر: Nephrologietherapeutique. 6(6)

مصطلحات موضوعية: Male, Rural Population, Logistic Models, Democratic Republic of the Congo, Diabetes Mellitus, Prevalence, Albuminuria, Humans, Mass Screening, Female, Middle Aged

الوصف: To determine the prevalence of microalbuminuria, macroalbuminuria and renal insufficiency at the time of screening for diabetes and impaired fasting glucose in the semi-rural area of Kisantu/DR Congo, and to identify determinants of pathological urinary albumin excretion (UAE).Step 1: diabetes (81 cases) and impaired fasting glucose (148 cases) tracking in the population (1898 subjects selected by a systematic survey). Step 2: urinary albumin and serum creatinine were measured and glomerular filtration rate was estimated (modification of the diet in renal disease [MDRD] equation). The determinants of pathological UAE were assessed by logistic regression.The prevalence of macroalbuminuria and microalbuminuria in diabetes was 12.0 and 45.2% respectively versus 0 and 13.7% in impaired fasting glucose. Determinants of pathological UAE were: diabetes (adjusted OR [aOR]: 7.01; 95% CI: 3.48-14.11), central obesity (aOR: 2.36 [1.16-4.80]), age less that 60 years (aOR: 2.12 [1.05-4.40]), hypertension [aOR: 3.30 (1.39-7.82)] and diabetic retinopathy (aOR: 3.12 [1.54-6.26]). Renal insufficiency (MDRD60ml/min/1.73m(2)) prevalence was 21.4% in diabetes and 3.8% in impaired fasting glucose.Microalbuminuria and macroalbuminuria are frequently detected during screening for diabetes and impaired fasting glucose in a semi-rural area in DR Congo. They are especially associated with age above 60 years, central obesity and hypertension. Early and integrated management of diabetes is essential to prevent renal failure in the population.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::941c37b1dc875e0e2d8d74357adcb204Test
https://pubmed.ncbi.nlm.nih.gov/20627763Test

المؤلفون: Makasa Mandja, Wemakoy Okitolonda, Nazaire Nseka, Risasi Makulo, Wivine Kimenyembo, Pierre Kimbondo, Carla Truyers, Dieudonné Kaimbo wa Kaimbo, Muel Telo Muyer, Ebanz'osongo Bieleli, Mala Ali Mapatano, Frank Buntinx, Erik Muls, Moise Mvitu

المساهمون: Family Medicine, RS: CAPHRI School for Public Health and Primary Care

المصدر: Journal of Clinical Epidemiology, 64(2), 172-181. Elsevier Science

مصطلحات موضوعية: Adult, Male, Pediatrics, medicine.medical_specialty, Cross-sectional study, Epidemiology, Population, Impaired glucose tolerance, Diabetes mellitus, Risk Factors, medicine, Prevalence, Humans, Obesity, education, education.field_of_study, Anthropometry, business.industry, Population-based survey, medicine.disease, Impaired fasting glucose, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Congo, Hyperglycemia, Africa, Albuminuria, Democratic Republic of the Congo, Feasibility Studies, Female, medicine.symptom, business, Sentinel Surveillance, Demography

الوصف: Objectives To study prevalence, determinants, and complications at diagnosis of diabetes and intermediate hyperglycemia (IH) in Kisantu, a semirural town in Bas-Congo province, Democratic Republic of Congo. Study Design and Setting A large-scale analytical cross-sectional population-based survey was performed in 2007 in Kisantu. After extensive sensitization, the study sample was collected using a modified World Health Organization (WHO) STEPwise strategy, taking subsequently a random sample of streets, households within streets, and inhabitants aged 20 years and older within households. After informed consent, subjects were invited to fixed sites for interview, anthropometry, clinical examination (blood pressure, monofilament, and ophthalmology), and biochemical tests (fasting capillary glucose, serum creatinine, and albuminuria). Fasting glycemia was repeated or 2-hour postload glycemia was measured the next day in subjects with an initial glycemia of 126–199 mg/dL (7.0–11.1 mmol/L) or 100–125 mg/dL (5.6–6.9 mmol/L), respectively. Hence, prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance according to both 2006 WHO/International Diabetes Federation and 2003 American Diabetes Association criteria could be evaluated. Bivariate and multivariate analyses were used for statistical analyses. Results Response rate was 93.7% (1,898 of 2,025). Complete data were available in 1,866 (92.1%) subjects. Conclusion Estimating the prevalence of diabetes and IH in a small Congolese town was proven to be feasible.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3254adbb5b8e67ea37df308b6f849861Test
https://pubmed.ncbi.nlm.nih.gov/20705425Test