المؤلفون: Rutherford, Nicola J, Zhang, Yong-Jie, Baker, Matt, Gass, Jennifer M, Finch, NiCole A, Xu, Ya-Fei, Stewart, Heather, Kelley, Brendan J, Kuntz, Karen, Crook, Richard JP, Sreedharan, Jemeen, Vance, Caroline, Sorenson, Eric, Lippa, Carol, Bigio, Eileen H, Geschwind, Daniel H, Knopman, David S, Mitsumoto, Hiroshi, Petersen, Ronald C, Cashman, Neil R, Hutton, Mike, Shaw, Christopher E, Boylan, Kevin B, Boeve, Bradley, Graff-Radford, Neill R, Wszolek, Zbigniew K, Caselli, Richard J, Dickson, Dennis W, Mackenzie, Ian R, Petrucelli, Leonard, Rademakers, Rosa

المصدر: PLOS Genetics. 4(9)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Rare Diseases, Neurodegenerative, Acquired Cognitive Impairment, Genetics, ALS, Brain Disorders, Neurosciences, Dementia, 2.1 Biological and endogenous factors, Aetiology, Neurological, Adult, Aged, Aged, 80 and over, Alleles, Amyotrophic Lateral Sclerosis, Cell Line, Tumor, Cohort Studies, DNA Mutational Analysis, DNA-Binding Proteins, Female, Humans, Male, Middle Aged, Mutation, Missense, Neurodegenerative Diseases, Pedigree, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/31n233jnTest

المؤلفون: Mehta, Sarju G, Watts, Giles Dj, Adamson, Jennifer L, Hutton, Mike, Umberger, Geanie, Xiong, Shuling, Ramdeen, Sheena, Lovell, Mark A, Kimonis, Virginia E, Smith, Charles D

المصدر: Genetics in Medicine. 9(1)

مصطلحات موضوعية: Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Aging, Neurosciences, Frontotemporal Dementia (FTD), Rare Diseases, Neurodegenerative, Alzheimer's Disease, Brain Disorders, Dementia, Genetics, Acquired Cognitive Impairment, 2.1 Biological and endogenous factors, Aetiology, Neurological, Adult, Apolipoproteins E, Female, Genes, Dominant, Genetic Predisposition to Disease, Genotype, Haplotypes, Humans, Male, Middle Aged, Muscular Diseases, tau Proteins, frontotemporal dementia, Paget's disease of bone, inclusion body myopathy, muscular dystrophy, apolipoprotein-E, valosin-containing protein, Clinical Sciences, Genetics & Heredity

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1bs8x8h0Test

المؤلفون: Mauricio, Rui, Benn, Caroline, Davis, John, Dawson, Gerry, Dawson, Lee A, Evans, Alison, Fox, Nick, Gallacher, John, Hutton, Mike, Isaac, John, Jones, Declan NC, Jones, Lesley, Lalli, Giovanna, Libri, Vincenzo, Lovestone, Simon, Moody, Catherine, Noble, Wendy, Perry, Hugh, Pickett, James, Reynolds, David, Ritchie, Craig, Rohrer, Jonathan D, Routledge, Carol, Rowe, James, Snyder, Heather, Spires-Jones, Tara, Swartz, Jina, Truyen, Luc, Whiting, Paul, Therapeutics for Dementia Consortium

مصطلحات موضوعية: Alzheimer's disease, Clinical trials, Dementia, Diagnosis, Disease-modifying treatment, Earlier detection, Genetic risk factors, Neurodegeneration, Target validation

وصف الملف: Electronic-eCollection; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/294583Test

الإتاحة: https://doi.org/10.17863/CAM.41691Test
https://www.repository.cam.ac.uk/handle/1810/294583Test

المؤلفون: Gass, Jennifer, Cannon, Ashley, Mackenzie, Ian R, Boeve, Bradley, Baker, Matt, Adamson, Jennifer, Crook, Richard, Melquist, Stacey, Kuntz, Karen, Petersen, Ron, Josephs, Keith, Pickering-Brown, Stuart M, Graff-Radford, Neill, Uitti, Ryan, Dickson, Dennis, Wszolek, Zbigniew, Gonzalez, John, Beach, Thomas G, Bigio, Eileen, Johnson, Nancy, Weintraub, Sandra, Mesulam, Marsel, White, Charles L, Woodruff, Bryan, Caselli, Richard, Hsiung, Ging-Yuek, Feldman, Howard, Knopman, Dave, Hutton, Mike, Rademakers, Rosa

المصدر: Gass , J , Cannon , A , Mackenzie , I R , Boeve , B , Baker , M , Adamson , J , Crook , R , Melquist , S , Kuntz , K , Petersen , R , Josephs , K , Pickering-Brown , S M , Graff-Radford , N , Uitti , R , Dickson , D , Wszolek , Z , Gonzalez , J , Beach , T G , Bigio , E , Johnson , N , Weintraub , S , Mesulam , M , White , C L , Woodruff , B ....

مصطلحات موضوعية: Adult, Aged, 80 and over, Amyotrophic Lateral Sclerosis, Brain Chemistry, Dementia, Founder Effect, Gene Dosage, Genotype, Humans, Intercellular Signaling Peptides and Proteins, Middle Aged, Mutation, Ubiquitin, Journal Article, Research Support, N.I.H., Extramural, Non-U.S. Gov't, ResearchInstitutes_Networks_Beacons/02/05, Dementia@Manchester

الإتاحة: https://doi.org/10.1093/hmg/ddl241Test
https://research.manchester.ac.uk/en/publications/1dd1ec10-5581-4b87-99e6-bcee845f2deeTest

المؤلفون: Mackenzie, Ian R A, Baker, Matt, Pickering-Brown, Stuart, Hsiung, Ging-Yuek R, Lindholm, Caroline, Dwosh, Emily, Gass, Jennifer, Cannon, Ashley, Rademakers, Rosa, Hutton, Mike, Feldman, Howard H

المصدر: Mackenzie , I R A , Baker , M , Pickering-Brown , S , Hsiung , G-Y R , Lindholm , C , Dwosh , E , Gass , J , Cannon , A , Rademakers , R , Hutton , M & Feldman , H H 2006 , ' The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene ' , Brain : a journal of neurology , vol. 129 , no. Pt 11 , pp. 3081-90 . https://doi.org/10.1093/brain/awl271Test

مصطلحات موضوعية: Aged, Corpus Striatum, Dementia, Female, Hippocampus, Humans, Immunoenzyme Techniques, Inclusion Bodies, Intercellular Signaling Peptides and Proteins, Intranuclear Inclusion Bodies, Male, Middle Aged, Mutation, Neocortex, Retrospective Studies, Ubiquitin, Journal Article, Research Support, N.I.H., Extramural, Non-U.S. Gov't, ResearchInstitutes_Networks_Beacons/02/05, Dementia@Manchester

الإتاحة: https://doi.org/10.1093/brain/awl271Test
https://research.manchester.ac.uk/en/publications/d7a87336-7696-4ef5-a229-2ac78dc8856bTest

المؤلفون: Pickering-Brown, Stuart, Momeni, Parastoo, Bell, Jason, Duckworth, Jaime, Hutton, Mike, Mann, David, Brown, Stuart Pickering, Hardy, John

المصدر: Pickering-Brown , S , Momeni , P , Bell , J , Duckworth , J , Hutton , M , Mann , D , Brown , S P & Hardy , J 2006 , ' Sequence analysis of all identified open reading frames on the frontal temporal dementia haplotype on chromosome 3 fails to identify unique coding variants except in CHMP2B ' , Neuroscience letters , vol. 410 , no. 2 , pp. 77-79 . https://doi.org/10.1016/j.neulet.2006.06.065Test

مصطلحات موضوعية: CHMP2B, Dementia, Genetics, ResearchInstitutes_Networks_Beacons/02/05, Dementia@Manchester

الإتاحة: https://doi.org/10.1016/j.neulet.2006.06.065Test
https://research.manchester.ac.uk/en/publications/8d1b59da-af1b-4838-8784-72acc8b7894eTest