Pimavanserin use in a movement disorders clinic: a single-center experience
| العنوان: | Pimavanserin use in a movement disorders clinic: a single-center experience |
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| المؤلفون: | Patricia Kaminski, Danette Taylor, Bisena Bulica, Abhimanyu Mahajan, Shana Krstevska, Neepa Patel, Ayesha Ahmad, Peter A LeWitt |
| المصدر: | Neurological Sciences. 39:1767-1771 |
| بيانات النشر: | Springer Science and Business Media LLC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Psychosis, medicine.medical_specialty, Parkinson's disease, Movement disorders, Pimavanserin, Dermatology, Severity of Illness Index, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Surveys and Questionnaires, Internal medicine, Severity of illness, medicine, Humans, Urea, Dementia, 030212 general & internal medicine, Adverse effect, Aged, Retrospective Studies, Aged, 80 and over, Movement Disorders, business.industry, Parkinsonism, General Medicine, Middle Aged, medicine.disease, Psychiatry and Mental health, Treatment Outcome, chemistry, Female, Neurology (clinical), medicine.symptom, business, Serotonin 5-HT2 Receptor Agonists, 030217 neurology & neurosurgery, Follow-Up Studies |
| الوصف: | Parkinson’s disease psychosis (PDP) is a disabling non-motor symptom of Parkinson’s disease (PD) that is challenging to treat. Dopamine receptor blockers (DRB) are used to treat PDP, though these may be associated with adverse effects, including worsening of Parkinsonism. Pimavanserin, a selective 5-HT2A receptor inverse agonist, was recently FDA-approved for treatment of PDP; however, there is limited information on its long-term use in PDP patients. A retrospective chart review of patients prescribed pimavanserin was performed in August, 2017. Data on demographics, psychotic features, sleep, and adverse effects was collected using a semi-structured telephone interview with patients or caregivers. Hallucination severity (HS) was quantified as mild ( |
| تدمد: | 1590-3478 1590-1874 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79287c5ef5b2adf897dac666b7e256a6Test https://doi.org/10.1007/s10072-018-3500-5Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....79287c5ef5b2adf897dac666b7e256a6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15903478 15901874 |
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