التفاصيل البيبلوغرافية
| العنوان: |
Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial. |
| المؤلفون: |
Mair, Grant, Kummer, Rüdiger, Adami, Alessandro, White, Philip, Adams, Matthew, Yan, Bernard, Demchuk, Andrew, Farrall, Andrew, Sellar, Robin, Ramaswamy, Rajesh, Mollison, Daisy, Boyd, Elena, Rodrigues, Mark, Samji, Karim, Baird, Andrew, Cohen, Geoff, Sakka, Eleni, Palmer, Jeb, Perry, David, Lindley, Richard |
| المصدر: |
Neuroradiology; Jan2015, Vol. 57 Issue 1, p1-9, 9p, 1 Diagram, 4 Charts, 1 Graph |
| مصطلحات موضوعية: |
CEREBRAL angiography, COMPUTED tomography, CONFIDENCE intervals, RESEARCH evaluation, STATISTICS, STROKE, DATA analysis, INTER-observer reliability, DATA analysis software, DESCRIPTIVE statistics |
| مستخلص: |
Introduction: CT angiography (CTA) is often used for assessing patients with acute ischaemic stroke. Only limited observer reliability data exist. We tested inter- and intra-observer reliability for the assessment of CTA in acute ischaemic stroke. Methods: We selected 15 cases from the Third International Stroke Trial (IST-3, ISRCTN25765518) with various degrees of arterial obstruction in different intracranial locations on CTA. To assess inter-observer reliability, seven members of the IST-3 expert image reading panel (>5 years experience reading CTA) and seven radiology trainees (<2 years experience) rated all 15 scans independently and blind to clinical data for: presence (versus absence) of any intracranial arterial abnormality (stenosis or occlusion), severity of arterial abnormality using relevant scales (IST-3 angiography score, Thrombolysis in Cerebral Infarction (TICI) score, Clot Burden Score), collateral supply and visibility of a perfusion defect on CTA source images (CTA-SI). Intra-observer reliability was assessed using independently repeated expert panel scan ratings. We assessed observer agreement with Krippendorff's-alpha (K-alpha). Results: Among experienced observers, inter-observer agreement was substantial for the identification of any angiographic abnormality (K-alpha = 0.70) and with an angiography assessment scale (K-alpha = 0.60-0.66). There was less agreement for grades of collateral supply (K-alpha = 0.56) or for identification of a perfusion defect on CTA-SI (K-alpha = 0.32). Radiology trainees performed as well as expert readers when additional training was undertaken (neuroradiology specialist trainees). Intra-observer agreement among experts provided similar results (K-alpha = 0.33-0.72). Conclusion: For most imaging characteristics assessed, CTA has moderate to substantial observer agreement in acute ischaemic stroke. Experienced readers and those with specialist training perform best. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
