المؤلفون: Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJB, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO, Van Den Weyngaert D, Kaendler S, Krauseneck P, Vinolas N, Villa S, Wurm RE, Maillot MHB, Spagnolli F, Kantor G, Malhaire JP, Renard L, De Witte O, Scandolaro L, Vecht CJ, Maingon P, Lutterbach J, Kobierska A, Bolla M, Souchon R, Mitine C, Tzuk-Shina T, Kuten A, Haferkamp G, de Greve J, Priou F, Menten J, Rutten I, Clavere P, Malmstrom A, Jancar B, Newlands E, Pigott K, Twijnstra A, Chinot O, Reni M, Boiardi A, Fabbro M, Campone M, Bozzino J, Frenay M, Gijtenbeek J, Delattre JY, De Paula U, Hanzen C, Pavanato G, Schraub S, Pfeffer R, Soffietti R, Kortmann RD, Taphoorn M, Torrecilla JL, Grisold W, Huget P, Forsyth P, Fulton D, Kirby S, Wong R, Fenton D, Cairncross G, Whitlock P, Burdette-Radoux S, Gertler S, Saunders S, Laing K, Siddiqui J, Martin LA, Gulavita S, Perry J, Mason W, Thiessen B, Pai H, Alam ZY, Eisenstat D, Mingrone W, Hofer S, Pesce G, Dietrich PY, Thum P, Baumert B, Ryan G

المساهمون: Stupp, R, Mason, Wp, van den Bent, Mj, Weller, M, Fisher, B, Taphoorn, Mjb, Belanger, K, Brandes, Aa, Marosi, C, Bogdahn, U, Curschmann, J, Janzer, Rc, Ludwin, Sk, Gorlia, T, Allgeier, A, Lacombe, D, Cairncross, Jg, Eisenhauer, E, Mirimanoff, Ro, Van Den Weyngaert, D, Kaendler, S, Krauseneck, P, Vinolas, N, Villa, S, Wurm, Re, Maillot, Mhb, Spagnolli, F, Kantor, G, Malhaire, Jp, Renard, L, De Witte, O, Scandolaro, L, Vecht, Cj, Maingon, P, Lutterbach, J, Kobierska, A, Bolla, M, Souchon, R, Mitine, C, Tzuk-Shina, T, Kuten, A, Haferkamp, G, de Greve, J, Priou, F, Menten, J, Rutten, I, Clavere, P, Malmstrom, A, Jancar, B, Newlands, E, Pigott, K, Twijnstra, A, Chinot, O, Reni, M, Boiardi, A, Fabbro, M, Campone, M, Bozzino, J, Frenay, M, Gijtenbeek, J, Delattre, Jy, De Paula, U, Hanzen, C, Pavanato, G, Schraub, S, Pfeffer, R, Soffietti, R, Kortmann, Rd, Taphoorn, M, Torrecilla, Jl, Grisold, W, Huget, P, Forsyth, P, Fulton, D, Kirby, S, Wong, R, Fenton, D, Cairncross, G, Whitlock, P, Burdette-Radoux, S, Gertler, S, Saunders, S, Laing, K, Siddiqui, J, Martin, La, Gulavita, S, Perry, J, Mason, W, Thiessen, B, Pai, H, Alam, Zy, Eisenstat, D, Mingrone, W, Hofer, S, Pesce, G, Dietrich, Py, Thum, P, Baumert, B, Ryan, G, Neurology, Plastic and Reconstructive Surgery and Hand Surgery

المصدر: New England Journal of Medicine, vol. 352, no. 10, pp. 987-96
New England Journal of Medicine, 352(10), 987-996. Massachussetts Medical Society

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Adrenal Cortex Hormones, Adrenal Cortex Hormones/therapeutic use Adult Aged Antineoplastic Agents, Alkylating/adverse effects/*therapeutic use Brain Neoplasms/*drug therapy/mortality/*radiotherapy Chemotherapy, Adjuvant Dacarbazine/adverse effects/*analogs & derivatives/*therapeutic use Disease Progression Female Glioblastoma/*drug therapy/mortality/*radiotherapy Humans Male Middle Aged Proportional Hazards Models Radiotherapy, Computer-Assisted/adverse effects Survival Analysis, medicine, Temozolomide, Humans, Survival rate, Pseudoprogression, Antineoplastic Agents, Alkylating, Aged, Proportional Hazards Models, business.industry, Brain Neoplasms, Hazard ratio, General Medicine, Middle Aged, Debulking, medicine.disease, Survival Analysis, Radiotherapy, Computer-Assisted, Surgery, Radiation therapy, Dacarbazine, Chemotherapy, Adjuvant, Concomitant, Disease Progression, Female, business, Glioblastoma, medicine.drug, Anaplastic astrocytoma

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf112f90a929a68afabcd377cbf792eaTest
https://doi.org/10.1056/NEJMoa043330Test

المؤلفون: Beauchesne, Patrick, Quillien, Véronique, Faure, Gérôme, Bernier, V., Noël, G., Quetin, P., Gorlia, T., Carnin, C., Pedeux, Remy

المساهمون: Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Institut de Génétique et Développement de Rennes (IGDR), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), CRLCC Eugène Marquis (CRLCC), Centre privé de radiothérapie, Centre C. Bernard, Institut de Cancérologie de Lorraine - Alexis Vautrin [Nancy] (UNICANCER/ICL), UNICANCER, Centre Paul Strauss : Centre Régional de Lutte contre le Cancer (CRLCC), Centre hospitalier régional Metz-Thionville (CHR Metz-Thionville), Microenvironnement et cancer (MiCa), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Oncogenesis Stress Signaling (OSS), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CRLCC Eugène Marquis (CRLCC), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes (UR)-CRLCC Eugène Marquis (CRLCC)

المصدر: International Journal of Cancer
International Journal of Cancer, Wiley, 2016, 138 (6), pp.1538-1544. ⟨10.1002/ijc.29898⟩
International Journal of Cancer, 2016, 138 (6), pp.1538-1544. ⟨10.1002/ijc.29898⟩

مصطلحات موضوعية: Ultrafractionated regimen, Adult, Male, Brain Neoplasms, [SDV]Life Sciences [q-bio], Tumor Suppressor Proteins, [SDV.CAN]Life Sciences [q-bio]/Cancer, Chemoradiotherapy, DNA Methylation, Middle Aged, Tumor Burden, Glioblastoma - Inoperable, Dacarbazine, DNA Repair Enzymes, Treatment Outcome, Low doses - Radiation therapy, Temozolomide, Humans, Female, France, Radiotherapy, Intensity-Modulated, Glioblastoma, Antineoplastic Agents, Alkylating, DNA Modification Methylases, Aged

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8b1b6313bad1b882e2705e1c4c3a8d53Test
https://pubmed.ncbi.nlm.nih.gov/26501997Test

المؤلفون: Agnihotri, S, Gajadhar, A, Ternamian, C, Gorlia, T, Diefes, K, Mischel, P, Kelly, Joanna, McGown, Gail, Thorncroft, Mary R, Carlson, B, Sarkaria, J, Margison, Geoffrey P, Aldape, K, Hawkins, C, Hegi, M, Guha, A

المساهمون: Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Ontario, Canada. sameer.agnihotri@utoronto.ca

مصطلحات موضوعية: Animals, Antineoplastic Agents, Alkylating, Cell Line, Tumor, DNA Glycosylases, DNA Modification Methylases, DNA Repair, DNA Repair Enzymes, Dacarbazine, Drug Resistance, Neoplasm, Gene Expression, Gene Knockdown Techniques, Glioblastoma, Humans, Mice, Inbred NOD, SCID, RNA, Small Interfering, Tumor Suppressor Proteins, Xenograft Model Antitumor Assays

العلاقة: Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients. 2012, 122 (1):253-66 J Clin Invest; http://hdl.handle.net/10541/230172Test; The Journal of Clinical Investigation

الإتاحة: https://doi.org/10.1172/JCI59334Test
http://hdl.handle.net/10541/230172Test

المؤلفون: Stupp, R., Hegi, M.E., Mason, W.P., van den Bent, M.J., Taphoorn, M.J., Janzer, R.C., Ludwin, S.K., Allgeier, A., Fisher, B., Belanger, K., Hau, P., Brandes, A.A., Gijtenbeek, J., Marosi, C., Vecht, C.J., Mokhtari, K., Wesseling, P., Villa, S., Eisenhauer, E., Gorlia, T., Weller, M., Lacombe, D., Cairncross, J.G., Mirimanoff, R.O.

المصدر: The lancet Oncology, vol. 10, no. 5, pp. 459-466

مصطلحات موضوعية: Antineoplastic Agents, Alkylating, Brain Neoplasms, Combined Modality Therapy, DNA Methylation, DNA Modification Methylases, DNA Repair Enzymes, Dacarbazine, Disease Progression, Female, Follow-Up Studies, Glioblastoma, Humans, Male, Middle Aged, Prognosis, Promoter Regions, Genetic, Survival Analysis, Survival Rate, Tumor Suppressor Proteins

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/19269895; info:eu-repo/semantics/altIdentifier/pissn/1474-5488[electronic]; https://serval.unil.ch/notice/serval:BIB_9F4B47E9A16ETest

الإتاحة: https://doi.org/10.1016/S1470-2045Test(09)70025-7
https://serval.unil.ch/notice/serval:BIB_9F4B47E9A16ETest

المؤلفون: van den Bent, M J, Taphoorn, M J B, Brandes, A A, Menten, Johan, Stupp, R, Frenay, M, Chinot, O, Kros, J M, van der Rijt, C C D, Vecht, Ch J, Allgeier, A, Gorlia, T

مصطلحات موضوعية: Adult, Antineoplastic Agents, Alkylating, Brain Neoplasms, Dacarbazine, Disease Progression, Drug Administration Schedule, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neoplasm Recurrence, Local, Oligodendroglioma, Treatment Outcome

العلاقة: Journal of Clinical Oncology vol:21 issue:13 pages:2525-2528; https://lirias.kuleuven.be/handle/123456789/34867Test; http://www.jco.org/cgi/pmidlookup?view=long&pmid=12829671Test

الإتاحة: https://lirias.kuleuven.be/handle/123456789/34867Test
http://www.jco.org/cgi/pmidlookup?view=long&pmid=12829671Test

المؤلفون: Thierry Gorlia, Denis Lacombe, Alba A. Brandes, Martin J. van den Bent, Michael Weller, Roger Stupp, Monika E. Hegi, René O. Mirimanoff, Karl Belanger, Elizabeth Eisenhauer, J. Gregory Cairncross, Anouk Allgeier

المساهمون: Neurology, University of Zurich, Gorlia, T

المصدر: Lancet Oncology, 9(1), 29-38. Lancet Publishing Group

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Population, 610 Medicine & health, law.invention, Randomized controlled trial, SDG 3 - Good Health and Well-being, law, Internal medicine, medicine, Temozolomide, Humans, education, Antineoplastic Agents, Alkylating, Survival analysis, Proportional Hazards Models, education.field_of_study, Performance status, Proportional hazards model, business.industry, Nomogram, Middle Aged, Prognosis, Combined Modality Therapy, Survival Analysis, 10040 Clinic for Neurology, Surgery, Clinical trial, Dacarbazine, Nomograms, 2730 Oncology, Female, business, Glioblastoma, medicine.drug

وصف الملف: Binder1VoAccMan.pdf - application/pdf; Gorlia_et_al_nomograms_2008-1VoPub.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d2b9b0beba84354866d3fe83752ac8Test
https://hdl.handle.net/1765/30386Test

المؤلفون: Anouk Allgeier, Warren P. Mason, Martin J. van den Bent, Salvador Villà, Thierry Gorlia, Rolf-Dieter Kortmann, Jüergen Curschmann, Roger Stupp, Barbara Fisher, Alba A. Brandes, René O. Mirimanoff, Gregory Cairncross, Denis Lacombe, Michele Reni

المساهمون: Neurology, Mirimanoff, Ro, Gorlia, T, Mason, W, Van den Bent, Mj, Kortman, Rd, Fisher, B, Reni, M, Brandes, Aa, Curschmann, J, Villa, S, Cairncross, G, Allgeier, A, Lacombe, D, Stupp, R

المصدر: Journal of Clinical Oncology, 24(16), 2563-2569. American Society of Clinical Oncology

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Canada, medicine.medical_treatment, Internal medicine, medicine, Clinical endpoint, Temozolomide, Humans, Survival rate, Antineoplastic Agents, Alkylating, Survival analysis, Aged, Performance status, business.industry, Brain Neoplasms, Cancer, Middle Aged, medicine.disease, Survival Analysis, Surgery, Radiation therapy, Dacarbazine, Europe, Treatment Outcome, Chemotherapy, Adjuvant, Concomitant, Female, Radiotherapy, Adjuvant, business, Glioblastoma, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319264beb6a2722ecd80df0db5b2494dTest
https://pubmed.ncbi.nlm.nih.gov/16735709Test