التفاصيل البيبلوغرافية
| العنوان: |
A View on the Chemical and Biological Attributes of Five Edible Fruits after Finishing Their Shelf Life: Studies on Caco-2 Cells. |
| المؤلفون: |
Pirvu, Lucia Camelia, Rusu, Nicoleta, Bazdoaca, Cristina, Androne, Elena, Neagu, Georgeta, Albulescu, Adrian |
| المصدر: |
International Journal of Molecular Sciences; May2024, Vol. 25 Issue 9, p4848, 28p |
| مصطلحات موضوعية: |
TABLE grapes, FRUIT, STRAWBERRIES, FRUIT juices, CYTOTOXINS, FRUIT extracts, APRICOT |
| مستخلص: |
We studied five common perishable fruits in terms of their polyphenols dynamic, minerals distribution, scavenger activity and the effects of 50% ethanolic extracts on the viability of Caco-2 cells in vitro, over a period of time between T = 0 and T = 5/7 days, typically the end of their shelf life. Altogether, there were few changes found, consisting of either an increase or a decrease in their chemical and biological attributes. A slow decrease was found in the antioxidant activity in apricot (−11%), plum (−6%) and strawberry (−4%) extracts, while cherry and green seedless table grape extracts gained 7% and 2% antioxidant potency, respectively; IC50 values ranged from 1.67 to 5.93 μg GAE/μL test extract. The cytotoxicity MTS assay at 24 h revealed the ability of all 50% ethanol fruit extracts to inhibit the Caco-2 cell viability; the inhibitory effects ranged from 49% to 83% and were measured at 28 µg GAE for strawberry extracts/EES, from 22 µg to 45 µg GAE for cherry extracts/EEC, from 7.58 to 15.16 µg GAE for apricot extracts/EEA, from 12.50 to 25.70 µg GAE for plum extracts/EEP and from 21.51 to 28.68 µg GAE for green table grape extracts/EEG. The MTS anti-proliferative assay (72 h) also revealed a stimulatory potency upon the Caco-2 viability, from 34% (EEA, EEG) and 48% (EEC) to 350% (EES) and 690% (EEP); therefore fruit juices can influence intestinal tumorigenesis in humans. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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