المؤلفون: Chiara Zambarda, Karolin Guldevall, Christian Breunig, Damien Toullec, Jacopo Fontana, Sheena Pinto, Jens Pahl, Susanne Wingert, Joachim Koch, Björn Önfelt

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

مصطلحات موضوعية: Pharmacology, Antibody-dependent cell-mediated cytotoxicity, Cancer Research, CD30, biology, Chemistry, medicine.drug_class, Immunology, Cell, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Monoclonal antibody, Immunological synapse, medicine.anatomical_structure, Cell killing, Oncology, medicine, Cancer research, biology.protein, Molecular Medicine, Immunology and Allergy, Cytotoxic T cell, Antibody, RC254-282

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b100f0a38751dbd8cb307946ee8d85Test
https://doaj.org/article/dde28aa9a42d4f86ae8c60c460702adfTest

المؤلفون: Maki Nakayama, Maikel Luis Colli, Yann Verdier, Noemi Brusco, Lut Overbergh, Mark J. Mamula, Aïsha Callebaut, Joëlle Vinh, Guido Sebastiani, Georgia Afonso, Laura Nigi, Matthieu Giraud, Barbara Brandao, Zhicheng Zhou, Sylvaine You, Alexia Carré, Mijke Buitinga, Sheena Pinto, Marie Eliane Azoury, Decio L. Eizirik, Francesco Dotta, Chantal Mathieu, Søren Buus, Roberto Mallone, Fatoumata Samassa, Ana Ines Lalanne, Magali Irla

المساهمون: Spectrométrie de Masse Biologique et Protéomique (USR3149 / FRE2032) (SMBP), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)

المصدر: Diabetes
Diabetes, American Diabetes Association, 2021, pp.db210259. ⟨10.2337/db21-0259⟩

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Endocrinology, Diabetes and Metabolism, Citrullination, 030209 endocrinology & metabolism, Peptide, Biology, Molecular biology, Epitope, 03 medical and health sciences, 0302 clinical medicine, chemistry, PADI2, PADI4, Internal Medicine, Cytotoxic T cell, [SDV.IMM]Life Sciences [q-bio]/Immunology, CD8, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, NOD mice

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a38375b241b82cebe35b607398e6eeaTest
https://doi.org/10.2337/figshare.16654669Test

المؤلفون: Joëlle Vinh, Aurore Pais, Sylvaine You, Etienne Larger, Decio L. Eizirik, Maikel Luis Colli, Laure Alexandre-Heymann, Danièle Dubois-Laforgue, Roberto Mallone, Søren Buus, Georgia Afonso, Graziella Bruno, Mahmoud Tarayrah, Cassandra Lavaud, Gonzalez-Duque Sergio, Jean-Paul Beressi, Sheena Pinto, Marie Eliane Azoury, Claire Maillard, Verdier Yann

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Université libre de Bruxelles (ULB), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Spectrométrie de Masse Biologique et Protéomique (USR3149 / FRE2032) (SMBP), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), University of Copenhagen = Københavns Universitet (UCPH), Centre Hospitalier de Versailles André Mignot (CHV), Università degli studi di Torino = University of Turin (UNITO), YOU, Sylvaine, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université de Paris (UP), University of Copenhagen = Københavns Universitet (KU), University of Turin, Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Center for Diabetes Research and Welbio [Brussels, Belgium] (Medical Faculty), INSERM U1016, Institut Cochin, Paris, France

المصدر: Diabetes
Diabetes, 2020, 69 (12), pp.2678-2690. ⟨10.2337/db20-0013⟩
Diabetes, American Diabetes Association, 2020, 69 (12), pp.2678-2690. ⟨10.2337/db20-0013⟩

مصطلحات موضوعية: 0301 basic medicine, biology, Effector, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], 030209 endocrinology & metabolism, Human leukocyte antigen, Nod, Epitope, Cell biology, [SDV] Life Sciences [q-bio], 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, MHC class I, Internal Medicine, biology.protein, Cytotoxic T cell, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, ComputingMilieux_MISCELLANEOUS, CD8, NOD mice

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1a19452588c10d10f72a2c18829d5eTest
https://www.hal.inserm.fr/inserm-03312401Test

المؤلفون: Matthias Kuhn, Karen Cerosaletti, Anna Lissina, Georgia Afonso, Raphael Scharfmann, Jean-Paul Beressi, Etienne Larger, Francesco Dotta, Bruno Kyewski, Laura Nigi, Howard W. Davidson, Guido Sebastiani, David Price, Manuela Battaglia, Roberto Mallone, Søren Buus, Klaudia Kuranda, Sheena Pinto, Slobodan Culina, Ezio Bonifacio, James E. McLaren, Victor Appay, Ana Inés Lalanne, Thomas Osterbye, Kristin Ladell, Sophie Caillat-Zucman, Anne Eugster, Alicia Maugein

المساهمون: Mallone, Roberto, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Sorbonne Paris Cité (USPC), Université Paris Descartes - Paris 5 (UPD5), Translational Research Program [Seattle, WA, USA], Benaroya Research Institute [Seattle, WA, USA], Division of Developmental Immunology [Heidelberg, Germany], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Department of Medicine, Surgery and Neuroscience [Siena, Italy] (Diabetes Unit), University Hospital of Siena [Italy]-Fondazione Umberto di Mario ONLUS [Siena, Italy]-Toscana Life Sciences [Siena, Italy], CRTD-DFG Research Center for Regenerative Therapies Dresden [Dresden, Germany] (Medical Faculty), Technische Universität Dresden = Dresden University of Technology (TU Dresden), Department of Immunology and Microbiology [Copenhagen], Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Division of Infection and Immunity [Cardiff, UK] (School of Medicine), Cardiff University, Service de diabétologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Diabétologie [CH Versailles André Mignot, Le Chesnay], Centre Hospitalier de Versailles André Mignot (CHV), Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Departement Hospitalo- Universitaire - Fight Ageing and STress [Paris] (DHU - FAST), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Barbara Davis Center for Childhood Diabetes (BDC), University of Colorado Anschutz [Aurora], Vaccine Research Center [Bethesda, MD, USA], National Institutes of Health [Bethesda] (NIH), Institut für Medizinische Informatik und Biometrie [Dresden, Germany] (Medical Faculty), Diabetes Research Institute [Milan, Italy], IRCCS Ospedale San Raffaele [Milan, Italy], Immunologie, génétique et traitement des maladies métaboliques et du diabète (UMR_S 561), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Jean Dausset d'Immunologie et d'Histocompatibilité [AP-HP Hôpital Saint-Louis], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], This work was performed within the Département Hospitalo-Universitaire AutHorS, supported by the Programme Hospitalier de Recherche Clinique ImMaDiab, Lilly France, the INSERM-Transfert Proof-of-Concept program acDC, the Ile-de-France CORDDIM, and grants from the JDRF (1-PNF-2014-155-A-V and 2-SRA-2016-164- Q-R), the Aviesan/Astra Zeneca 'Diabetes and the Vessel Wall Injury' program, the Société Francophone du Diabète, the Agence Nationale de la Recherche (ANR-2015-CE17-0018-01), the Fondation pour la Recherche Médicale (Equipe FRM DEQ20140329520), and the Helmsley Charitable Trust George S. Eisenbarth nPOD Award for Team Science (2015PG-T1D052) (to R.M.), a JDRF Biomarkers grant (17-2012-598) (to K.C.), an NIH R01 grant (DK052068) (to H.W.D.), Lilly and Fondation Bettencourt-Schueller funds (to R.S.), a European Research Council grant (ERC-2012-AdG) (to B.K.), and funds from JDRF, the Wellcome Trust, and the National Institute for Health Research Cambridge Biomedical Research Centre [to the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory (Cambridge Institute for Medical Research, University of Cambridge), which provided PBMC samples from the JDRF D-GAP study]. Samples from at-risk patients were obtained through a TrialNet ancillary study to the TN-01 Pathway to Prevention study funded by NIH grants U01 DK061010, U01 DK061034, U01 DK061042, U01 DK061058, U01 DK085465, U01 DK085453, U01 DK085461, U01 DK085463, U01 DK085466, U01 DK085499, U01 DK085504, U01 DK085505, U01 DK085509, U01 DK103180, U01- DK103153, U01-DK085476, and U01-DK103266 and by JDRF. D.A.P. is a Wellcome Trust Senior Investigator (100326Z/12/Z). This research was performed with the support of the nPOD, a collaborative T1D research project funded by JDRF. Organ procurement organizations partnering with nPOD to provide research resources are listed at www.jdrfnpod.org/ for-partners/npod-partners/. This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (INNODIA, no. 115797). This Joint Undertaking receives support from the Union’s Horizon 2020 research and innovation program and the European Federation of Pharmaceutical Industries and Associations, JDRF, and the Leona M. and Harry B. Helmsley Charitable Trust., Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Centre d'Immunologie et de Maladies Infectieuses (CIMI), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), National Institutes of Health [Bethesda] (NIH)-National Institutes of Health, Bethesda

المصدر: Science Immunology
Science Immunology, 2018, 3 (20), ⟨10.1126/sciimmunol.aao4013⟩
Science Immunology, American Association for the Advancement of Science, 2018, 3 (20), ⟨10.1126/sciimmunol.aao4013⟩

مصطلحات موضوعية: 0301 basic medicine, geography, endocrine system, geography.geographical_feature_category, endocrine system diseases, [SDV.IMM] Life Sciences [q-bio]/Immunology, T cell, Immunology, General Medicine, Biology, Islet, Epitope, 3. Good health, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Antigen, Cell culture, Interferon, medicine, Cytotoxic T cell, [SDV.IMM]Life Sciences [q-bio]/Immunology, CD8, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787a7fec2e9c93b9cae858cfe4689cdaTest
https://www.hal.inserm.fr/inserm-01918833/documentTest

المؤلفون: Thomas Blankenstein, Bruno Kyewski, Sheena Pinto, Dolores J. Schendel, Wolfgang Uckert, Susanne Wilde, Daniel Sommermeyer, Chloé Michel

المصدر: European Journal of Immunology. 44:2811-2821

مصطلحات موضوعية: integumentary system, Immunology, T-cell receptor, Biology, Molecular biology, Epitope, Interleukin 21, Antigen, Transcription (biology), Immunology and Allergy, Cytotoxic T cell, Central tolerance, neoplasms, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3a44a0ba76d9fb411e37f23443bd8ff6Test
https://doi.org/10.1002/eji.201444499Test

المؤلفون: Sheena Pinto, Gisela Eisenhardt, Thomas J. Hoffmann, Larisa Buselic-Wölfel, Christoph Steeneck, Ulrich Deuschle, Claus Kremoser, Manfred Birkel, Michael Albers, Simon Anderhub

المصدر: Cancer Research. 79:1210-1210

مصطلحات موضوعية: Cancer Research, biology, Chemistry, T cell, medicine.medical_treatment, respiratory system, Aryl hydrocarbon receptor, Interleukin 22, Immune system, medicine.anatomical_structure, Oncology, Cancer immunotherapy, Cancer cell, Cancer research, biology.protein, medicine, Cytotoxic T cell, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::49b671b22ab8f90e48cb999731a57b9fTest
https://doi.org/10.1158/1538-7445.am2019-1210Test

المؤلفون: Sheena Pinto, Slobodan Culina, Mathieu Armanet, Marie Eliane Azoury, Guido Sebastiani, Jean Paul Beressi, Maikel Luis Colli, Marco Bugliani, Yann Verdier, Roberto Mallone, Lars M. Steinmetz, Alexia Carré, Francesco Dotta, Gonzalez-Duque Sergio, Piero Marchetti, Noémie Corcos, Jean Valéry Turatsinze, Georgia Afonso, Decio L. Eizirik, Marc Diedisheim, Bruno Kyewski, Laura Nigi, Danièle Dubois-Laforgue, Raphael Scharfmann, Joëlle Vinh, Etienne Larger, Søren Buus, Graziella Bruno, Sylvaine You, Ana Inés Lalanne

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Sorbonne Paris Cité (USPC), Spectrométrie de Masse Biologique et Protéomique (USR3149 / FRE2032) (SMBP), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5), Center for Diabetes Research and Welbio [Brussels, Belgium] (Medical Faculty), Université libre de Bruxelles (ULB), Department of Medicine, Surgery and Neuroscience [Siena, Italy] (Diabetes Unit), University Hospital of Siena [Italy]-Fondazione Umberto di Mario ONLUS [Siena, Italy]-Toscana Life Sciences [Siena, Italy], Division of Developmental Immunology [Heidelberg, Germany], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Department of Clinical and Experimental Medicine [Pisa, Italy], University of Pisa [Italy], Cell Therapy Unit [AP-HP Hôpital Saint-Louis], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de diabétologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Hôpital Cochin [AP-HP], Department of Genetics [Stanford], Stanford Medicine, Stanford University-Stanford University, Genome Biology Unit [Heidelberg, Germany], European Molecular Biology Laboratory [Hinxton], Department of Immunology and Microbiology [Copenhagen], Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Service de Diabétologie [CH Versailles André Mignot, Le Chesnay], Centre Hospitalier de Versailles André Mignot (CHV), Department of Medical Sciences [Turin, Italy] (DMS), University of Turin, This work was performed within the Département Hospitalo-Universitaire (DHU) AutHorS and supported by a PhD fellowship of the Ile-de-France CORDDIM and Aide aux Jeunes Diabétiques and by grants from the JDRF (1-PNF-2014-155-A-V, 2-SRA-2016-164-Q-R), the Agence Nationale de la Recherche (ANR-2015-CE17-0018-01), the Fondation pour la Recherche Médicale (DEQ20140329520), the Société Francophone du Diabète, the Association pour la Recherche sur le Diabète, and the Helmsley Charitable Trust Eisenbarth nPOD Award for Team Science (2015PG-T1D052) to R.M., Lilly and Fondation Bettencourt-Schueller to R.S., European Research Council (ERC-2012-AdG) to B.K., FRFSWelbio (CR-2015A-06) and NIH-NIDDK-HIRN Consortium (1UC4DK104166-01) to D.L.E., and Ile-de-France SESAME 2010 (10022268), the City of Paris, and ESPCI Paris to J.V. This project received funding from the Innovative Medicines Initiative 2 Joint Undertaking (INNODIA, 115797), which receives support from the EU Horizon 2020 program, the European Federation of Pharmaceutical Industries and Associations, JDRF, and the Helmsley Charitable Trust. This research was supported by nPOD, a collaborative T1D research project funded by JDRF. Organ Procurement Organizations partnering with nPOD are listed at www.jdrfnpod.org/ourpartners.php., ANR-15-CE17-0018,TIBET,LA PRESSION ENVIRONNEMENTALE SUR UNE IMAGE ALTEREE DU SOI IMMUNITAIRE : VERS LA PREDICTION ET LA PREVENTION DU DIABETE DE TYPE 1(2015), Mallone, Roberto, LA PRESSION ENVIRONNEMENTALE SUR UNE IMAGE ALTEREE DU SOI IMMUNITAIRE : VERS LA PREDICTION ET LA PREVENTION DU DIABETE DE TYPE 1 - - TIBET2015 - ANR-15-CE17-0018 - AAPG2015 - VALID, Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Pisa - Università di Pisa, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Università degli studi di Torino = University of Turin (UNITO)

المصدر: Cell Metabolism
Cell Metabolism, Elsevier, 2018, 28 (6), pp.946-960. ⟨10.1016/j.cmet.2018.07.007⟩
Cell Metabolism, 28 (6
Cell Metabolism, 2018, 28 (6), pp.946-960. ⟨10.1016/j.cmet.2018.07.007⟩

مصطلحات موضوعية: 0301 basic medicine, Proteomics, endocrine system diseases, Corticotropin-Releasing Hormone, Physiology, type 1 diabetes, Epitopes, T-Lymphocyte, urocortin, CD8-Positive T-Lymphocytes, Epitope, Mice, 0302 clinical medicine, HLA Antigens, Physiologie générale, Cytotoxic T cell, Insulin, Urocortins, Antigen Presentation, epitope, Antigen processing, autoimmunity, 3. Good health, Islet Amyloid Polypeptide, human leukocyte antigen (HLA), Proprotein Convertase 2, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, secretogranin, Preproinsulin, endocrine system, [SDV.IMM] Life Sciences [q-bio]/Immunology, antigen, preproinsulin, proconvertase, transpeptidation, Molecular Biology, Cell Biology, 030209 endocrinology & metabolism, Human leukocyte antigen, Biology, Cell Line, 03 medical and health sciences, Neuroendocrine Secretory Protein 7B2, Antigen, Downregulation and upregulation, Animals, Humans, Protein Precursors, Biologie moléculaire, 030104 developmental biology, Diabetes Mellitus, Type 1, Case-Control Studies, Immunology, Biologie cellulaire, Transcriptome, CD8, Biomarkers

وصف الملف: 2 full-text file(s): application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff6e270c5bef0ee6ba99c23259793a6Test