المؤلفون: Godefridus J. Peters, Isabella Vittimberga, Editta Baldini, Myriam Chartoire, Luca Boni, Marcello Tiseo, Matteo Brighenti, Fausto Barbieri, Andrea Camerini, Elisa Giovannetti, Francesca Mazzoni, Carmelo Tibaldi, Annalisa Gilli, Richard J. Honeywell

المساهمون: CCA - Imaging and biomarkers, Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system

المصدر: British journal of cancer, 119(11), 1326-1331. Nature Publishing Group
British Journal of Cancer, 119(11), 1326-1331. Nature Publishing Group
Tibaldi, C, Camerini, A, Tiseo, M, Mazzoni, F, Barbieri, F, Vittimberga, I, Brighenti, M, Boni, L, Baldini, E, Gilli, A, Honeywell, R, Chartoire, M, Peters, G J, Giovannetti, E & Italian Oncological Group of Clinical Research (GOIRC) 2018, ' Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer : a prospective validation study ', British Journal of Cancer, vol. 119, no. 11, pp. 1326-1331 . https://doi.org/10.1038/s41416-018-0307-3Test
British Journal of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Predictive markers, Deoxycytidine, Article, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Medical research, Internal medicine, Carcinoma, Non-Small-Cell Lung, Cytidine Deaminase, Antineoplastic Combined Chemotherapy Protocols, medicine, Carcinoma, Biomarkers, Tumor, Humans, Prospective Studies, Prospective cohort study, Lung cancer, Survival rate, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Retrospective cohort study, Cytidine deaminase, Middle Aged, medicine.disease, Prognosis, Gemcitabine, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Cisplatin, business, Non-small-cell lung cancer, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a41cf0b0a4002de132af4198423642Test
https://pure.amc.nl/en/publications/cytidine-deaminase-enzymatic-activity-is-a-prognostic-biomarker-in-gemcitabineplatinumtreated-advanced-nonsmallcell-lung-cancer-a-prospective-validation-studyTest(297ba0b2-d07b-4b73-bc30-89fce3b095d5).html

المؤلفون: Richard J. Honeywell, Joseph Ciccolini, Nienke Losekoot, Cindy Serdjebi, M. Maulandi, M.C. Etienne-Grimaldi, Elisa Giovannetti, G.J. Peters, G. Milano

المساهمون: Medical oncology laboratory, CCA - Innovative therapy

المصدر: Nucleosides, Nucleotides and Nucleic Acids, 33(4-6), 403-412. Taylor and Francis Ltd.
Peters, G J, Honeywell, R J, Maulandi, M, Giovannetti, E, Losekoot, N, Etienne-Grimaldi, M C, Milano, G, Serdjebi, C & Ciccolini, J 2014, ' Selection of the Best Blood Compartment to Measure Cytidine Deaminase Activity to Stratify for Optimal Gemcitabine Or Cytarabine Treatment ', Nucleosides, Nucleotides and Nucleic Acids, vol. 33, no. 4-6, pp. 403-412 . https://doi.org/10.1080/15257770.2014.894196Test

مصطلحات موضوعية: Adult, Male, Cytidine deaminase activity, Cost-Benefit Analysis, Pharmacology, Biochemistry, Deoxycytidine, chemistry.chemical_compound, Young Adult, Cytidine Deaminase, Genetics, medicine, Humans, Dosing, Whole blood, Enzyme Assays, Chemistry, Cytarabine, Reproducibility of Results, Cytidine, General Medicine, Cytidine deaminase, Middle Aged, Gemcitabine, Toxicity, Molecular Medicine, Female, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc886224b3c27ee84817938ec30aa529Test
https://doi.org/10.1080/15257770.2014.894196Test

المؤلفون: Valentina Mey, S. Nannizzi, M. Del Tacca, Enrico Vasile, Alfredo Falcone, Cinzia Orlandini, Andrea Antonuzzo, R. Di Marsico, G.J. Peters, A.C. Laan, Romano Danesi, Carmelo Tibaldi, Elisa Giovannetti, S. Ricciardi

المساهمون: Medical oncology laboratory, CCA - Oncogenesis

المصدر: Clinical Cancer Research, 14(6), 1797-1803. American Association for Cancer Research Inc.
Tibaldi, C, Giovannetti, E, Vasile, E, Mey, V, Laan, A C, Nannizzi, S, Di Marsico, R, Antonuzzo, A, Orlandini, C, Ricciardi, S, Del Tacca, M, Peters, G J, Falcone, A & Danesi, R 2008, ' Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients ', Clinical Cancer Research, vol. 14, no. 6, pp. 1797-1803 . https://doi.org/10.1158/1078-0432.CCR-07-1364Test

مصطلحات موضوعية: Adult, Male, Cancer Research, Lung Neoplasms, medicine.drug_class, Biology, Antimetabolite, Deoxycytidine, Polymorphism, Single Nucleotide, Carcinoma, Non-Small-Cell Lung, Cytidine Deaminase, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Lung cancer, Aged, Retrospective Studies, Xeroderma Pigmentosum Group D Protein, Cisplatin, gemcitabine, lung cancer, Predictive marker, Cancer, Cytidine deaminase, Middle Aged, medicine.disease, Endonucleases, Prognosis, Survival Analysis, Gemcitabine, DNA-Binding Proteins, Treatment Outcome, Oncology, Immunology, Cancer research, Disease Progression, Female, ERCC1, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e634fc8624ca39f2f9d9768ca74abd4cTest
https://research.vumc.nl/en/publications/8cc12f1f-7d3e-490c-be6e-77d108ffcbc2Test

المؤلفون: Elisa Giovannetti, Sara Nannizzi, Grazia Savarino, Romano Danesi, Valentina Mey, S. Ricciardi, G. Barsanti, Lucia Loni, Mario Del Tacca

المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, CCA - Cancer Treatment and quality of life, AII - Cancer immunology

المصدر: Giovannetti, E, Mey, V, Loni, L, Nannizzi, S, Barsanti, G, Savarino, G, Ricciardi, S, Del Tacca, M & Danesi, R 2007, ' Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells ', Pharmacological Research, vol. 55, no. 4, pp. 343-349 . https://doi.org/10.1016/j.phrs.2007.01.003Test
Pharmacological Research, 55(4), 343-349. Academic Press Inc.

مصطلحات موضوعية: Male, Apoptosis, Jurkat cells, Deoxycytidine, Jurkat Cells, ARA-C, Tumor Cells, Cultured, Cytotoxic T cell, MESSENGER-RNA EXPRESSION, Cytotoxicity, 5'-Nucleotidase, Reverse Transcriptase Polymerase Chain Reaction, Cell Cycle, PROLONGED-INFUSION GEMCITABINE, CHRONIC LYMPHOCYTIC-LEUKEMIA, DEOXYCYTIDINE KINASE, LYMPHOBLASTIC-LEUKEMIA, Deoxycytidine kinase, Cytidine deaminase, Cell cycle, Middle Aged, Gene Expression Regulation, Neoplastic, Treatment Outcome, Female, medicine.drug, Antimetabolites, Antineoplastic, Ribonucleoside Diphosphate Reductase, Cell Survival, Biology, Gene Expression Regulation, Enzymologic, Immunophenotyping, Equilibrative Nucleoside Transporter 1, Antigens, CD, Predictive Value of Tests, medicine, Humans, RNA, Messenger, Aged, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, Gene Expression Profiling, Patient Selection, Tumor Suppressor Proteins, Reproducibility of Results, Molecular biology, Leukemia, Lymphocytic, Chronic, B-Cell, Gemcitabine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8699c8260ad34361c50621e0e465d9d2Test
http://hdl.handle.net/11568/195392Test

المؤلفون: Mauro Iannopollo, Generoso Bevilacqua, Mario Del Tacca, Elisa Giovannetti, Marco Del Chiaro, Sergio Ricci, Valentina Mey, Cinzia Orlandini, Franco Mosca, Ugo Boggi, Niccola Funel, Sara Nannizzi, Daniela Campani, Romano Danesi

المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, CCA - Cancer Treatment and quality of life, AII - Cancer immunology

المصدر: Cancer Research, 66(7), 3928-3935. American Association for Cancer Research Inc.
Giovannetti, E, Del Tacca, M, Mey, V, Funel, N, Nannizzi, S, Ricci, S, Orlandini, C, Boggi, U, Campani, D, Del Chiaro, M, Iannopollo, M, Bevilacqua, G, Mosca, F & Danesi, R 2006, ' Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine ', Cancer Research, vol. 66, no. 7, pp. 3928-3935 . https://doi.org/10.1158/0008-5472.CAN-05-4203Test

مصطلحات موضوعية: Oncology, Male, Cancer Research, Gene Expression, biosynthesis/genetics, Equilibrative nucleoside transporter 1, Deoxycytidine, chemistry.chemical_compound, analogs /&/ derivatives/therapeutic use, drug therapy/genetics/metabolism, Gene expression, 80 and over, 5'-Nucleotidase, Aged, 80 and over, Tumor, biology, Reverse Transcriptase Polymerase Chain Reaction, Cytidine deaminase, Deoxycytidine kinase, Middle Aged, Prognosis, Treatment Outcome, Female, medicine.drug, Adult, Transcriptional Activation, medicine.medical_specialty, Ribonucleoside Diphosphate Reductase, medicine.drug_class, Antimetabolite, Cell Line, Equilibrative Nucleoside Transporter 1, Predictive Value of Tests, Cell Line, Tumor, Internal medicine, Cytidine Deaminase, Deoxycytidine Kinase, medicine, Humans, Aged, Tumor Suppressor Proteins, Cancer, biosynthesis/genetics, Adult, Aged, Aged, 80 and over, Cell Line, Tumor, Cytidine Deaminase, biosynthesis/genetics, Deoxycytidine Kinase, biosynthesis/genetics, Deoxycytidine, analogs /&/ derivatives/therapeutic use, Equilibrative Nucleoside Transporter 1, biosynthesis/genetics, Female, Gene Expression, Humans, Male, Middle Aged, Pancreatic Neoplasms, drug therapy/genetics/metabolism, Predictive Value of Tests, Prognosis, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleoside Diphosphate Reductase, biosynthesis/genetics, Transcriptional Activation, Treatment Outcome, Tumor Suppressor Proteins, medicine.disease, Gemcitabine, Pancreatic Neoplasms, Endocrinology, chemistry, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6d2d3df983d8be442b23b709742771Test
http://hdl.handle.net/11568/237302Test

المؤلفون: M. Del Tacca, Valentina Guarneri, Ugo Boggi, Elisa Giovannetti, A Fontana, E. Fontana, Franco Mosca, Monica Lencioni, Pierfranco Conte, Romano Danesi, Carmelo Bengala, Valentina Mey, M Del Chiaro, Sergio Ricci

المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, CCA - Cancer Treatment and quality of life, AII - Cancer immunology

المصدر: Bengala, C, Guarneri, V, Giovannetti, E, Lencioni, M, Fontana, E, Mey, V, Fontana, A, Boggi, U, Del Chiaro, M, Danesi, R, Ricci, S, Mosca, F, Del Tacca, M & Conte, P F 2005, ' Prolonged fixed dose rate infusion of gemcitabine with autologous haemopoietic support in advanced pancreatic adenocarcinoma ', British Journal of Cancer, vol. 93, no. 1, pp. 35-40 . https://doi.org/10.1038/sj.bjc.6602673Test
British Journal of Cancer, 93(1), 35-40. Nature Publishing Group
British Journal of Cancer

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Pancreatic disease, drug therapy/therapy, Maximum Tolerated Dose, medicine.drug_class, pancreatic cancer, Adenocarcinoma, Antimetabolite, Drug Administration Schedule, fixed dose rate infusion, Pharmacokinetics, drug therapy/therapy, Adult, Aged, Base Sequence, Combined Modality Therapy, DNA Primers, Drug Administration Schedule, Female, Hematopoietic Stem Cell Transplantation, Humans, Male, Maximum Tolerated Dose, Middle Aged, Pancreatic Neoplasms, drug therapy/therapy, Pharmacogenetics, Treatment Outcome, Pancreatic cancer, Internal medicine, Clinical Studies, medicine, Humans, Aged, DNA Primers, cytidine deaminase, Base Sequence, business.industry, Hematopoietic Stem Cell Transplantation, Middle Aged, medicine.disease, Combined Modality Therapy, Gemcitabine, Pancreatic Neoplasms, Endocrinology, Treatment Outcome, Pharmacogenetics, Toxicity, Female, gemcitabine pharmacokinetic, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445f27a6b8e83ff3835a13d3b2cfdac8Test
https://hdl.handle.net/11380/305754Test