Indications, feasibility, safety, and efficacy of CyberKnife radiotherapy for the treatment of olfactory groove meningiomas: a single institutional retrospective series
| العنوان: | Indications, feasibility, safety, and efficacy of CyberKnife radiotherapy for the treatment of olfactory groove meningiomas: a single institutional retrospective series |
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| المؤلفون: | Ekkehard M. Kasper, Farhan A Mirza, Rafael Rojas, Anand Mahadevan, Fred C. Lam, Jianmin Liu |
| المصدر: | Radiation Oncology (London, England) Radiation Oncology, Vol 15, Iss 1, Pp 1-10 (2020) |
| بيانات النشر: | BioMed Central, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | lcsh:Medical physics. Medical radiology. Nuclear medicine, Male, medicine.medical_specialty, Olfactory groove meningiomas, lcsh:R895-920, medicine.medical_treatment, Radiosurgery, lcsh:RC254-282, Resection, Stereotactic radiotherapy, 03 medical and health sciences, 0302 clinical medicine, Cyberknife, Olfactory Groove Meningioma, medicine, Meningeal Neoplasms, Humans, Radiology, Nuclear Medicine and imaging, Stereotactic radiosurgery, Aged, Retrospective Studies, Aged, 80 and over, Fractionated stereotactic radiotherapy, Hypofractionated stereotactic radiotherapy, business.industry, Research, Rate control, CyberKnife radiotherapy, Radiotherapy Dosage, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Radiation therapy, Survival Rate, Oncology, 030220 oncology & carcinogenesis, Feasibility Studies, Female, Radiation Dose Hypofractionation, Radiology, Radiotherapy, Intensity-Modulated, Post treatment, business, Meningioma, 030217 neurology & neurosurgery |
| الوصف: | Purpose To assess the safety and efficacy of CyberKnife® radiotherapy (CKRT) for the treatment of olfactory groove meningiomas (OGMs). Methods A retrospective review was performed of 13 patients with OGM treated with CKRT from September 2005 to May 2018 at our institution. Nine patients were treated primarily with CKRT, 3 for residual disease following resection, and 1 for disease recurrence. Results Five patients were treated with stereotactic radiosurgery (SRS), 6 with hypofractionated stereotactic radiotherapy (HSRT), and 2 with fractionated stereotactic radiotherapy (FSRT). The median tumor volume was 8.12 cm3. The median prescribed dose was 14.8 Gy for SRS, 27.3 Gy for HSRT, and 50.2 Gy for FSRT. The median maximal dose delivered was 32.27 Gy. Median post treatment follow-up was 48 months. Twelve of 13 patients yielded a 100% regional control rate with a median tumor volume reduction of 31.7%. Six of the 12 patients had reduced tumor volumes while the other 6 had no changes. The thirteenth patient had significant radiation-induced edema requiring surgical decompression. Twelve patients were alive and neurologically stable at the time of the review. One patient died from pneumonia unrelated to his CKRT treatment. Conclusions CKRT appears to be safe and effective for the treatment of OGMs. |
| اللغة: | English |
| تدمد: | 1748-717X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e94d1f7c760e607a5bd4e3def70cd9Test http://europepmc.org/articles/PMC7069021Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....17e94d1f7c760e607a5bd4e3def70cd9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1748717X |
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