المؤلفون: Surace, Laura, Doisne, Jean-Marc, Croft, Carys, A, Thaller, Anna, Escoll, Pedro, Marie, Solenne, Petrosemoli, Natalia, Guillemot, Vincent, Dardalhon, Valerie, Topazio, Davide, Cama, Antonia, Buchrieser, Carmen, Taylor, Naomi, Amit, Ido, Musumeci, Olimpia, Di Santo, James, P

المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), École Doctorale Bio Sorbonne Paris Cité Paris (ED562 - BioSPC), Université Sorbonne Paris Cité (USPC)-Université Paris Cité (UPCité), Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria, Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Otolaryngology, Ospedale “Giuseppe Mazzini” di Teramo, Department of Maxillofacial and Otolaryngology, Hospital "Floraspe Renzetti", Department of Immunology Rehovot, Israël, Weizmann Institute of Science Rehovot, Israël, Department of Clinical and Experimental Medicine Messina, Italy, University of Messina, The Innate Immunity Unit is supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur, the Agence National pour le Recherche (ANR) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (695467, ILC_REACTIVITY). A.T. is supported by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement no. 765104. C.B.’s group was supported by the Fondation pour la Recherche Médicale (FRM) grant no. EQU201903007847 and the grant no. ANR-10-LABX-62-IBEID. L.S. was supported by an SNSF-Early PostDoc. Mobility fellowship and a Marie Curie grant (H2020- MSCA-IF-2017)., We thank all the members of the Innate Immunity Unit for helpful discussions, the Centre de Recherche Translationnelle and the logistic department of Institut Pasteur. We thank the CB-UTechS platform for cytometry support and the Imagopole-CiTech (part of France-BioImaging supported by ANR grant no. ANR-10-INSB-04-01, Conseil de la Region Ile-de-France, FRM) for technical support., The study was conceptualized by L.S. and J.P.D. Experiments were coordinated by L.S. FACS and subsequent analyses were performed by L.S., C.A.C., A.T., J.-M.D. and S.M. Confocal microscopy analysis was performed by P.E., C.B. and L.S. Bioinformatic analyses were performed by N.P. and V.G. RNA-seq experiments were conducted by I.A. O.M., V.D., N.T., D.T. and A.C. provided resources. L.S. and J.P.D. wrote the paper. Funding was acquired by L.S. and J.P.D., and the study was supervised by J.P.D., ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016), European Project: 765104,MATURE-NK, European Project: 796004,BIF-SCV

المصدر: ISSN: 1529-2908.

مصطلحات موضوعية: MESH: Amino Acids, Branched-Chain, MESH: Arginine, MESH: Cytokines, MESH: Energy Metabolism, MESH: Humans, MESH: Immunity, Innate, MESH: Interleukin-33, MESH: Lymphocyte Activation, MESH: Mitochondria, MESH: Mitochondrial Diseases, MESH: Phenotype, MESH: Th2 Cells, MESH: Case-Control Studies, MESH: Cell Proliferation, MESH: Cells, Cultured, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34686862; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; info:eu-repo/grantAgreement//765104/EU/MAnufacturing of TUmour-REactive Natural Killer cells/MATURE-NK; info:eu-repo/grantAgreement//796004/EU/H2020-MSCA-IF-2017 Bifurcations in several complex variables/BIF-SCV; pasteur-03499188; https://pasteur.hal.science/pasteur-03499188Test; https://pasteur.hal.science/pasteur-03499188/documentTest; https://pasteur.hal.science/pasteur-03499188/file/2021_Nat%20Immunol_Surace.pdfTest; PUBMED: 34686862; PUBMEDCENTRAL: PMC8553616

الإتاحة: https://doi.org/10.1038/s41590-021-01043-8Test
https://pasteur.hal.science/pasteur-03499188Test
https://pasteur.hal.science/pasteur-03499188/documentTest
https://pasteur.hal.science/pasteur-03499188/file/2021_Nat%20Immunol_Surace.pdfTest

المؤلفون: Zompi, Simona, Hamerman, Jessica A, Ogasawara, Kouetsu, Schweighoffer, Edina, Tybulewicz, Victor L J, Di Santo, James P, Lanier, Lewis L, Colucci, Francesco

المصدر: Nature immunology. 4(6)

مصطلحات موضوعية: 1-Phosphatidylinositol 3-Kinase, Animals, Cytotoxicity, Immunologic, Enzyme Precursors, Female, Killer Cells, Natural, Male, Membrane Glycoproteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Neoplasms, Experimental, Protein-Tyrosine Kinase, Receptors, Immunologic, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Signal Transduction, Tumor Cells, Cultured, ZAP-70 Protein-Tyrosine Kinase

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3ks6r7kxTest

المؤلفون: Sepulveda, Fernando E, Maschalidi, Sophia, Vosshenrich, Christian A. J., Garrigue, Alexandrine, Kurowska, Mathieu, Ménasche, Gaël, Fischer, Alain, Di Santo, James P, de Saint Basile, Geneviève

المساهمون: Laboratory of Normal and Pathological Homeostasis of the Immune System, Institut National de la Santé et de la Recherche Médicale (INSERM), Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunité Innée, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'immuno-hématologie pédiatrique CHU Necker, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Collège de France - Chaire Médecine expérimentale (A. Fischer), Collège de France (CdF (institution)), Centre d'étude des Déficits Immunitaires, This work was supported by fellowships from the Association pour la Recherche sur le Cancer and Becas Chile (F.E.S.) and by fellowships from the Association pour la Recherche sur le Cancer and the Imagine Foundation (S.M.). This work was also supported by the French National Institutes of Health and Medical Research (INSERM), the Agence National de la Recherche (HLH-Cytotox/ANR-12-BSV1-0020-01), the ARC Foundation (grant PJA 2013120047), the European Research Council (PIDImmun, advanced grant 249816), and the Imagine Foundation., ANR-12-BSV1-0020,HLH-cytotox,Bases moléculaires et physiopathologie des syndromes hémophagocytaires(2012), European Project: 249816,EC:FP7:ERC,ERC-2009-AdG,PIDIMMUN(2010)

المصدر: ISSN: 0006-4971.

مصطلحات موضوعية: MESH: Animals, MESH: Cell Proliferation, MESH: Killer Cells, Natural/pathology, Natural/virology, MESH: Lymphocytic Choriomeningitis/virology, MESH: Lymphocytic Choriomeningitis/immunology, MESH: Lymphocytic Choriomeningitis/pathology, MESH: Lymphocytic choriomeningitis virus/immunology, MESH: Lymphohistiocytosis, Hemophagocytic/immunology, Hemophagocytic/pathology, Hemophagocytic/virology, MESH: Mice, MESH: Spleen/pathology, Inbred C57BL, MESH: Spleen/immunology, MESH: Spleen/virology, MESH: Cells, Cultured, MESH: T-Lymphocytes, Cytotoxic/immunology, MESH: Viral Load, MESH: Cytotoxicity, Immunologic/immunology, MESH: Interferon-gamma/secretion, Natural/immunology, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25525117; info:eu-repo/grantAgreement/EC/FP7/249816/EU/Primary immunodeficiency diseases as models for the study of the immune system/PIDIMMUN; pasteur-01489214; https://pasteur.hal.science/pasteur-01489214Test; https://pasteur.hal.science/pasteur-01489214/documentTest; https://pasteur.hal.science/pasteur-01489214/file/Pasteur-01489214_Sepulveda.pdfTest; PUBMED: 25525117

الإتاحة: https://doi.org/10.1182/blood-2014-09-602946Test
https://pasteur.hal.science/pasteur-01489214Test
https://pasteur.hal.science/pasteur-01489214/documentTest
https://pasteur.hal.science/pasteur-01489214/file/Pasteur-01489214_Sepulveda.pdfTest

المؤلفون: García-Ojeda, Marcos, E., Klein Wolterink, Roel, G. J., Lemaître, Fabrice, Richard Le Goff, Odile, Hasan, Milena, Hendriks, Rudolf, W., Cumano, Ana, Di Santo, James, P.

المساهمون: Immunité Innée, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Développement des Lymphocytes, Erasmus University Medical Center Rotterdam (Erasmus MC), Cellule Pasteur, Université Paris Diderot - Paris 7 (UPD7)-PRES Sorbonne Paris Cité, Dynamiques des Réponses Immunes, Centre d'Immunologie Humaine (CIH), This work was supported by a fellowship from the Pasteur Foundation (M.E.G.-O.), by grants from the Huygens Scholarship Program and the Royal Netherlands Academy for Arts and Sciences (both the Netherlands) and by the Ligue Nationale Contre le Cancer (France, R.G.J.K.W.). This work was also supported by grants from the Institut Pasteur, the Inserm, and the Ligue Nationale Contre le Cancer (all in France, J.P.D.).

المصدر: ISSN: 0006-4971.

مصطلحات موضوعية: b-lymphocytes, gata3 gene, t-lymphocytes, MESH: Animals, MESH: B-Lymphocytes, MESH: Cell Lineage, MESH: Cells, Cultured, MESH: Female, MESH: Flow Cytometry, MESH: GATA3 Transcription Factor, MESH: Male, MESH: Mice, Knockout, MESH: Receptor, Notch1, MESH: Receptors, Antigen, T-Cell, alpha-beta, MESH: Signal Transduction, MESH: T-Lymphocytes, MESH: Thymus Gland, MESH: Transcription Factors, MESH: Cell Differentiation, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/23287858; pasteur-03431420; https://pasteur.hal.science/pasteur-03431420Test; PUBMED: 23287858

الإتاحة: https://doi.org/10.1182/blood-2012-06-440065Test
https://pasteur.hal.science/pasteur-03431420Test

المؤلفون: Alves, Nuno L., Richard-Le Goff, Odile, Huntington, Nicholas D., Sousa, Ana Patricia, Ribeiro, Vera S. G., Bordack, Allison, Vives, Francina Langa, Peduto, Lucie, Chidgey, Ann, Cumano, Ana, Boyd, Richard, Eberl, Gerard, Di Santo, James P.

المساهمون: Cytokines et Développement Lymphoïde, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Développement des Lymphocytes, Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Institut Pasteur Paris (IP), Développement des Tissus Lymphoïdes, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Monash Immunology and Stem Cell Laboratories (MISCL), Monash University Clayton

المصدر: ISSN: 0027-8424.

مصطلحات موضوعية: MESH: Animals, MESH: Cells, Cultured, MESH: RNA, Messenger, MESH: Thymus Gland, MESH: Chromosomes, Artificial, Bacterial, MESH: Epithelial Cells, MESH: Genes, Reporter, MESH: Interleukin-7, MESH: Luminescent Proteins, MESH: Mice, Transgenic, MESH: Polymerase Chain Reaction, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/19164539; pasteur-00428982; https://hal-pasteur.archives-ouvertes.fr/pasteur-00428982Test; PUBMED: 19164539; PUBMEDCENTRAL: PMC2635771

الإتاحة: https://doi.org/10.1073/pnas.0809559106Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-00428982Test

المؤلفون: Blachère, Nathalie E, Morris, Heather K, Braun, Deborah, Saklani, Hélène, Di Santo, James P, Darnell, Robert B, Albert, Matthew L

المساهمون: Rockefeller University New York, Immunobiologie des Cellules Dendritiques, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cytokines et Développement Lymphoïde, Laboratory of Molecular Neuro-oncology, Howard Hughes Medical Institute (HHMI)-Rockefeller University New York, This work was supported by Pasteur Foundation (to N.E.B.), Howard Hughes Medical Institute (to N.E.B. and R.B.D.), La Fondation pour la Recherche Médicale (to D.B.), The Ligue Nationale Contre le Cancer, and European Young Investigator Awards scheme, European Science Foundation (to M.L.A.).

المصدر: ISSN: 0022-1767.

مصطلحات موضوعية: MESH: 3T3 Cells, MESH: Animals, MESH: Receptors, Interleukin, Interleukin-12, MESH: Antigens, CD40, MESH: Signal Transduction, MESH: T-Lymphocytes, Helper-Inducer, Viral, MESH: CD8-Positive T-Lymphocytes, MESH: Cell Differentiation, MESH: Cells, Cultured, MESH: Cross-Priming, MESH: Influenza A virus, MESH: Dendritic Cells, MESH: Immunologic Memory, MESH: Interferon-gamma, MESH: Interleukin-2, MESH: Lymphocyte Activation, MESH: Mice, Inbred BALB C, Inbred C57BL, Knockout, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/16751372; pasteur-01402330; https://hal-pasteur.archives-ouvertes.fr/pasteur-01402330Test; PUBMED: 16751372

الإتاحة: https://doi.org/10.4049/jimmunol.176.12.7288Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402330Test

المؤلفون: Samson, Sandrine, I., Mémet, Sylvie, Vosshenrich, Christian A. J., Colucci, Francesco, Richard, Odile, Ndiaye, Delphine, Israël, Alain, Di Santo, James, P.

المساهمون: Cytokines et Développement Lymphoïde, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Supported by grants from the Institut Pasteur, Institut National de la Santé et la Recherche Medicale (Inserm), the Ligue National Contre le Cancer (LNCC), and the Association pour le Recherche contre le Cancer (ARC). S.I.S. was supported by fellowships from the MENRT, the LNCC, and the ARC. C.A.J.V. was supported by a Poste Vert fellowship from Inserm.

المصدر: ISSN: 0006-4971.

مصطلحات موضوعية: natural killer cells, mice, chimera organism, MESH: Animals, MESH: Cell Differentiation, MESH: NF-KappaB Inhibitor alpha, MESH: NF-kappa B, MESH: Proto-Oncogene Proteins, MESH: Spleen, MESH: Cells, Cultured, MESH: Chimera, MESH: Cytokines, MESH: I-kappa B Proteins, MESH: Killer Cells, Natural, MESH: Liver, MESH: Mice, Inbred C57BL, Inbred Strains, Knockout, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/14764534; pasteur-03109750; https://pasteur.hal.science/pasteur-03109750Test; PUBMED: 14764534

الإتاحة: https://doi.org/10.1182/blood-2003-08-2975Test
https://pasteur.hal.science/pasteur-03109750Test