التفاصيل البيبلوغرافية
| العنوان: |
Long‐term study of tubeless insulin pump therapy compared to multiple daily injections in youth with type 1 diabetes: Data from the German/Austrian DPV registry. |
| المؤلفون: |
Danne, Thomas, Schwandt, Anke, Biester, Torben, Heidtmann, Bettina, Rami‐Merhar, Birgit, Haberland, Holger, Müther, Silvia, Khodaverdi, Semik, Haak, Thomas, Holl, Reinhard W., for the DPV Initiative |
| المصدر: |
Pediatric Diabetes; Aug2018, Vol. 19 Issue 5, p979-984, 6p, 2 Charts, 1 Graph |
| مصطلحات موضوعية: |
TYPE 1 diabetes, TREATMENT of diabetes, COMPARATIVE studies, REPORTING of diseases, GLYCOSYLATED hemoglobin, INJECTIONS, INSULIN, INSULIN pumps, BODY mass index, TREATMENT effectiveness, RETROSPECTIVE studies, TREATMENT duration, GLYCEMIC control, ADOLESCENCE |
| مصطلحات جغرافية: |
AUSTRIA, GERMANY |
| مستخلص: |
Objective: To examine glycemic control in youth with type 1 diabetes (T1D) who switched from multiple daily injections (MDI) to a tubeless insulin pump (Omnipod Insulin Management System, Insulet Corporation, Billerica, Massachusetts) compared to patients who continued MDI therapy over a 3‐year time period. Research Design and Methods: This retrospective analysis of the German/Austrian Diabetes Patienten Verlaufsdokumentation registry included data from 263 centers and 2529 patients <20 years (n = 660 tubeless insulin pump; n = 1869 MDI) who initiated treatment on a tubeless insulin pump as of January 1, 2013 and had 1 year of data preswitch from MDI and 3 years of data postswitch to a tubeless pump. Outcomes included the change in glycated hemoglobin (HbA1c), insulin dose, and body mass index (BMI) SD score (SDS). Results: Youth with T1D who switched from MDI therapy to a tubeless insulin pump showed better glycemic control at 1 year compared to patients who continued MDI treatment, adjusted mean ± SE: 7.5% ± 0.03% (58 mmol/mol) vs 7.7% ± 0.02% (61 mmol/mol); P < .001, with no between‐group difference at 2 and 3 years. Total daily insulin dose was lower (P < .001) in the tubeless insulin pump group, 0.80 ± 0.01, 0.81 ± 0.01, and 0.85 ± 0.01 U/kg, vs the MDI group, 0.89 ± 0.01, 0.94 ± 0.01, and 0.97 ± 0.01 U/kg, at 1, 2, and 3 years, respectively (all P < .001). BMI SDS increased in both groups and was not different over time. Conclusions: Treatment with a tubeless insulin pump in youth with T1D was associated with improvements in glycemic control compared to MDI after 1 year and appears to be an effective alternative to MDI. [ABSTRACT FROM AUTHOR] |
|
Copyright of Pediatric Diabetes is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
