التفاصيل البيبلوغرافية
| العنوان: |
Influence of a 100-km Ultra-Marathon on Hepatitis B Carrier Runners. |
| المؤلفون: |
Y.-H. Chiu, S.-K. Hou, C.-K. How, L.-H. Li, W.-F. Kao, C.-C. Yang, S.-L. Chou, Y.-T. S. Shiau, C. Lam, R.-J. Chen |
| المصدر: |
International Journal of Sports Medicine; Sep2013, Vol. 34 Issue 9, p841-845, 5p, 4 Charts |
| مصطلحات موضوعية: |
ASPARTATE aminotransferase, C-reactive protein, CARRIER state (Communicable diseases), STATISTICAL correlation, CREATINE kinase, FISHER exact test, HEPATITIS B, INTERLEUKINS, LACTATE dehydrogenase, RESEARCH funding, STATISTICS, TUMOR necrosis factors, U-statistics, DATA analysis, ALANINE aminotransferase, LONG-distance running, CASE-control method, DATA analysis software, DESCRIPTIVE statistics |
| مصطلحات جغرافية: |
TAIWAN |
| مستخلص: |
This study compares the serological markers between runners who are hepatitis B virus carries (HBVc) and runners who are non-HBVc in a 100-km ultra-marathon race. Blood samples of 8 HBVc and 18 non-HBVc runners were drawn 1 week before, immediately following, and 24 h after the race. Samples were analyzed and compared between the 2 groups for liver function tests, muscle damage markers and oxidative stress cytokines. For HBVc runners, HBV-DNA (hepatitis B virus-deoxyribonucleic acid) levels were also evaluated for virus reactivation. The results demonstrate a statistically signifi cant increase in both immediate and 24-h post-race values for alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), creatine kinase (CK), high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), compared with pre-race values. No statistically signifi cant diff erence was observed between the 2 groups for the values of AST, LDH, CK, hs-CRP, IL-6 and TNF-α either before or after the race. There was also no statistically signifi cant change in the levels of HBV-DNA in HBVc runners. These findings suggest that HBVc runners do not have higher risks of liver function impairment, muscle breakdown and inflammatory response compared to non-HBVc runners in such endurance races. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
