المؤلفون: Raffier B, Hirschi M, Trautinger F, Schmidt P, Stetter M, Hundstorfer M, Reinhart V, Monshi B, Pirkhammer D, Richter L, Hamberger N, Metz S, Feldmann R, Semmelweis K, Lackner K, Tomi N, Kolle H, Hafner F, Brodmann M, Kuen Spiegel M, Minmair G, Heil PM, Broil H, Holzer G, Illmer X, Rintelen B, Sautner J, Takacs M, Thun M, Zemanova I, Soukup T, Smrzova A, Bohmova J, Prochazkova L, Nemec P, Fojtik Z, Suchy D, Becvar R, Olsen AB, Sondergaard KH, Luosu jarvi R, Vidqvist KL, Madaule S, Beneton N, Maillard H, Charlanne H, GranelBrocard F, Hachulla E, Hatron PY, Jourdain N, Lambert M, Launay D, Morell S, Woijtasik G, Skowron F, Zenone T, Dadban A, Lok C, Ferrandiz D, MagyBertrand N, Moiton MP, Taieb A, Balquiere S, Belin E, Droitcourt C, Julien S, Prey S, Boulon C, Constans J, Doutre MS, Kostrzwewa E, Richez C, Greco M, Misery L, Sassolas B, Collet E, Berthier S, Leguy Seguin V, Imbert B, Carpentier P, Blaise S, Couraud A, Doeffel Hantz V, Spars A, Bezanahary H, Boussely N, Dumonteil S, Fauchais AL, Goudran G, Loustaud Ratti V, Manea P, Vidal E, Coppere B, DesmursClavel H, Girard Madoux MH, Hot A, Ninet J, Granel B, Cohen JD, Keynote A, Khau van Kien A, Le Quellec A, Riviere S, Rullier P, Bessis D, Farcas C, Bravetti V, Moline T, Wahl D, Zuily S, Granel Brocard F, Agard C, Durant C, Fuzibet JG, Queyrel V, Berezne A, Guillevin L, Mouthon L, Cabane J, Tiev K, Toledano C, Lazareth I, Michon Pasturel U, Priollet P, Reguiai Z, CazaletsLacoste C, Jego P, Letremy A, Perlat A, Duval Modeste AB, Chatelus E, Chiffot H, Sibillia J, Sordet C, Adoue D, Couret B, Moulis G, Pugnet G, Sailler L, Diot E, Gaches F, Farge D, Keshtmand H, Frances C, von Elling A, Bora D, Ebel J, Ahmadi Simab K, Klein E, Hahn K, Schulze K, Rasche C, Riemekasten G, Lee HH, Deuschle K, Mattat K, Becker M, Worm M, Mensing C, Klings D, Mensing H, Messall J, Zuper R, Eilbacher P, Saar P, Kaufmann P, Hallermann C, Schmidt K, Wahn H, Schildt K, Schuart T, Kaczmarczyk A, Kellner C, von Oelhafen J, Baron von Bildering P, Kunze S, Kleiner HJ, Alsheimer B, Schuetz N, Miirker Hermann E, Gottl KH, Weiss E, Reischel N, Kern S, Goettl KH, GoetheUniversitiitsklinikum JW, Himsel A, Henkemeier U, Schwarting A, Hazenbiller A, Nichelmann V, Rumbaur C, Boesenberg I, Schmeiser T, Mueller Ladner U, Unholzer A, Starz H, Welzel J, Plaumann K, Stoeckl F, Sperling S, Podda M, Wagner N, Rapprich H, Niedermeier A, Messer G, Sardy M, Bekou V, Dill MUller D, Wlodarz M, Belloni B, Huettig B, Ziai M, Hein R, Kneitz C, Federow I, Schneider K, Semmler M, Hapke S, Metzler C, Stein T, Enderlein M, Kayser M, Werthmann M, Guenther CU, Neul S, Hellmich B, Loeffler C, Pflugfelder J, Karaenke P, Mueglich C, Tony HP, Marina P, Popp M, Mittag M, Baumann C, Scheib EG, Brand H, Wilhelm HU, Bohm J, Dyballa J, Boehm J, Taggeselle J, LUthke K, Wuerzburg I, Niefanger K, Mayer L, Drabek J, Harmuth W, Dietl S, Moritz D, Gause A, Gaubitz M, Hallecker A, Krupp E, Rumpel H, Moosig F, Frey P, Kahl S, Linke M, Merk B, Bloching HH, Ochs W, Kurthen R, Eiden E, Guertler I, Aries PM, Kirchberg S, Jahnke K, Mettler S, Toeller S, Zwenger S, Langer HE, Deininger F, Hartmann F, Neeck G, Neek G, Wernitzsch H, Meier L, Herr U, Meier U, Aaig W, Bruckner L, Sheikh N, Wollenhaupt J, Krog B, Wollersdorfer E, Hall R, Diehm C, Tiggers C, Peters J, Kirschke J, Schroeder JO, Zeuner R, Uhlig S, Barth S, Huegel R, Glaeser R, Schaefer C, Monshausen M, Mengden T, Funkert A, Blank N, Lupaschko S, Voss B, Megahed M, Sadeghlar F, Seidel M, Wasmuth JC, Kreuter A, Vosswinkel J, Pfoehler C, Gerber A, Haust M, Hoff NP, Mota R, Akanay Diesel S, Homey B, Katzemich A, Erfurt Berge C, Sticherling M, Beyer C, Distler J, Mitchell A, Freundlieb C, Rushentsova U, Hermanns G, Blaschke S, Fiene M, Wessel C, Norgauer J, Rabe B, Schuster J, Scholz J, Kremer K, Robakidze Torbahn M, Moinzadeh P, Dohse A, Muhlack A, Schultz L, Schult S, Frambach Y, Kruse S, Kettenbach A, Fell I, Schweda K, Steinbrink K, Podobinska M, Fieri beck G, Schanz S, Pfeiffer C, Hassel R, Herrgott I, Sunderkoetter C, Guenzel J, Athanassiou P, Dimitroulas T, Settas L, Kritikos I, Tsifetaki N, Garyfallos A, Vasilopoulos D, Boura P, Kamali S, Aslanidis S, Vlachoyannopoulos P, Galanopoulo V, Sakkas L, Koutroubas A, Elezoglou T, Galanopoulos N, Grier A, Murray M, O'Rourke M, Del Papa N, Maglione W, Zeni S, Foti R, Benenati A, De Vita S, Ferraccioli G, Grassi W, de Angeli R, Pomponio G, Mussi A, Colonna L, Airo P, Zingarelli S, Scorza R, Serverino A, Puppo F, Negrini S, Roma I, Salsano F, Triolo G, Mazzuca S, Carignola R, Gatti S, Lunardi G, Riccieri V, Bajocchi G, Varcasia G, Marasini B, Belloll L, Matucci Cerinic M, de Luca R, Stisi S, Bellissimo S, Fusaro E, Pellerito R, Cozzi F, Rizzo M, Bartoluzzi A, Trotta F, Cantatore F, Corrado A, Malavolta N, Mule R, Galeazzi M, Lapadula G, Mathieu A, Vacca A, Giacomelli R, Cipriani P, Montecucco CM, Codullo V, Bucci R, Battaglia E, Valentini G, Cuomo G, Terlizzi N, Serafino L, Reumatologia UO, Bombardieri S, Della Rossa A, Doveri M, Perricone R, de Mattia M, Pallotta S, Groenendael JH, Seys P, Goekoop RJ, Han KH, Wlarvens M, Bonte Mineur F, de Bois MH, de Beus WM, van Zeben D, Vonk M, Knaapen HK, Smit A, Bootsma H, Ton E, Voskuyl A, Dutmer EA, Stalk JN, Madland TM, Seip M, Hoffmann Vold AM, Bitter H, Stocklund Thomsen R, Resende C, Ponte C, Martinho S, Silva F, Ferreira P, Grilo A, Riso N, Santos C, Camara I, Costa J, Alves J, Oliveira S, Almeida I, Silva I, Cordeiro A, Coelho P, Lukac J, Dolnicar AS, Espinosa G, Mejia JC, Ramos M, Plasin Rodriguez MA, Mera A, Blanco JS, Diaz JJ, Losada L, Perez E, Maneiro JR, Caamano M, Fermindez S, Insua SA, Barbado J, Fonseca EM, Nufio FJ, Castellvi I, Garcia de Ia Pena P, Bellido D, Paulino M, Garcia PV, Salas V, Minguez MD, Sanchez MA, Urrego C, Martin I, Rueda A, Calvo J, Ripoll MM, Torres MC, Corteguera M, Maceiras F, Cruz J, Mosquera JA, Gomez R, Area B, Carrio I, Rubio M, Castellvi Barranco I, Santos P, Simeon CP, Fonollosa V, Egurbide MV, Garcia de Vicuna R, Vicente E, Villaverde V, Fernandez C, Garcia E, Uson J, Miguelez R, Callejas JL, Ortego N, Roman J, Alegre Sancho JJ, Robles A, Rios JJ, Bonilla MG, Sanchez Andrade A, Vazquez TR, Miranda JA, Saez L, Zea A, De la Puente C, Martinez FG, Aguirre MA, Collado P, Cruz A, Crespo M, Sanchez Roman J, Castillo MJ, Garcia AM, Muniz G, Hedin PJ, Stahl C, Bracin T, Nordin A, Albertsson K, Rydvald Y, Thorsson C, Hermansson E, Maurer B, Verner D, Schmidt Bosshard R, Hall F, Murphy K, Lamb J, Anderson M, Moots R, Buch M, Bissell L, Madhok R, Hampson R, D'Cruz D, Choong LM, Gordon P, Dobson J, Salerno R, Nisar M, Williams C, Wilcox L, Denton C, Ochiel R, Ngcozana T, Parker L, Vincent R, McHugh N, Cole S, Brown S, James J, Herrick A, Manning J, Moore T, Faizal A, Skyes H, Smythe A, Hamilton A., SALVARANI, CARLO, FERRI, Clodoveo, COLACI, Michele

المساهمون: Raffier, B, Hirschi, M, Trautinger, F, Schmidt, P, Stetter, M, Hundstorfer, M, Reinhart, V, Monshi, B, Pirkhammer, D, Richter, L, Hamberger, N, Metz, S, Feldmann, R, Semmelweis, K, Lackner, K, Tomi, N, Kolle, H, Hafner, F, Brodmann, M, Kuen Spiegel, M, Minmair, G, Heil, Pm, Broil, H, Holzer, G, Illmer, X, Rintelen, B, Sautner, J, Takacs, M, Thun, M, Zemanova, I, Soukup, T, Smrzova, A, Bohmova, J, Prochazkova, L, Nemec, P, Fojtik, Z, Suchy, D, Becvar, R, Olsen, Ab, Sondergaard, Kh, Luosu jarvi, R, Vidqvist, Kl, Madaule, S, Beneton, N, Maillard, H, Charlanne, H, Granelbrocard, F, Hachulla, E, Hatron, Py, Jourdain, N, Lambert, M, Launay, D, Morell, S, Woijtasik, G, Skowron, F, Zenone, T, Dadban, A, Lok, C, Ferrandiz, D, Magybertrand, N, Moiton, Mp, Taieb, A, Balquiere, S, Belin, E, Droitcourt, C, Julien, S, Prey, S, Boulon, C, Constans, J, Doutre, M, Kostrzwewa, E, Richez, C, Greco, M, Misery, L, Sassolas, B, Collet, E, Berthier, S, Leguy Seguin, V, Imbert, B, Carpentier, P, Blaise, S, Couraud, A, Doeffel Hantz, V, Spars, A, Bezanahary, H, Boussely, N, Dumonteil, S, Fauchais, Al, Goudran, G, Loustaud Ratti, V, Manea, P, Vidal, E, Coppere, B, Desmursclavel, H, Girard Madoux, Mh, Hot, A, Ninet, J, Granel, B, Cohen, Jd, Keynote, A

مصطلحات موضوعية: Adult, Disability Evaluation, Employment, Female, Finger, Human, Male, Middle Aged, Registrie, Scleroderma, Systemic, Self Report, Skin Ulcer, Activities of Daily Living, Cost of Illness

الوصف: OBJECTIVES: Digital ulcers (DUs) are frequent manifestations of systemic scleroderma (SSc). This study assessed functional limitations due to DUs among patients enrolled in the Digital Ulcer Outcome (DUO) Registry, an international, multicentre, observational registry of SSc patients with DU disease. METHODS: Patients completed at enrolment a DU-specific functional assessment questionnaire with a 1-month recall period, measuring impairment in work and daily activities, and hours of help needed from others. Physician-reported clinical parameters were used to describe the population. For patients who completed at least part of the questionnaire, descriptive analyses were performed for overall results, and stratified by number of DUs at enrolment. RESULTS: This study included 2327 patients who completed at least part of the questionnaire. For patients with 0, 1-2, and ≥3 DUs at enrolment, mean overall work impairment during the prior month among employed/self-employed patients was 28%, 42%, and 48%, respectively. Across all included patients, ability to perform daily activities was impaired on average by 35%, 54%, and 63%, respectively. Patients required a mean of 2.0, 8.7, and 8.8 hours of paid help and 17.0, 35.9, and 63.7 hours of unpaid help, respectively, due to DUs in the prior month. Patients with DUs had more complications and medication use than patients with no DUs. CONCLUSIONS: With increasing number of DUs, SSc patients reported more impairment in work and daily activities and required more support from others.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/23910613; info:eu-repo/semantics/altIdentifier/wos/WOS:000330268000012; volume:31 (2 Suppl 76); firstpage:71; lastpage:80; journal:CLINICAL AND EXPERIMENTAL RHEUMATOLOGY; http://hdl.handle.net/11380/982514Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84883760726

الإتاحة: http://hdl.handle.net/11380/982514Test

المؤلفون: Guillevin, L, Hunsche, E, Denton, Cp, Krieg, T, Schwierin, B, Rosenberg, D, Matucci-Cerinic, M, Raffier, B, Hirschi, M, Trautinger, F, Schmidt, P, Stetter, M, Hundstorfer, M, Reinhart, V, Monshi, B, Pirkhammer, D, Richter, L, Hamberger, N, Metz, S, Feldmann, R, Semmelweis, K, Lackner, K, Tomi, N, Kolle, H, Hafner, F, Brodmann, M, Kuen-Spiegel, M, Minmair, G, Heil, Pm, Broil, H, Holzer, G, Illmer, X, Rintelen, B, Sautner, J, Takacs, M, Thun, M, Zemanova, I, Soukup, T, Smrzova, A, Bohmova, J, Prochazkova, L, Nemec, P, Fojtik, Z, Suchy, D, Becvar, R, Olsen, Ab, Sondergaard, Kh, Luosu jarvi, R, Vidqvist, Kl, Madaule, S, Beneton, N, Maillard, H, Charlanne, H, Granelbrocard, F, Hachulla, E, Hatron, Py, Jourdain, N, Lambert, M, Launay, D, Morell, S, Woijtasik, G, Skowron, F, Zenone, T, Dadban, A, Lok, C, Ferrandiz, D, Magybertrand, N, Moiton, Mp, Taieb, A, Balquiere, S, Belin, E, Droitcourt, C, Julien, S, Prey, S, Boulon, C, Constans, J, Doutre, Ms, Kostrzwewa, E, Richez, C, Greco, M, Misery, L, Sassolas, B, Collet, E, Berthier, S, Leguy-Seguin, V, Imbert, B, Carpentier, P, Blaise, S, Couraud, A, Doeffel-Hantz, V, Spars, A, Bezanahary, H, Boussely, N, Dumonteil, S, Fauchais, Al, Goudran, G, Loustaud-Ratti, V, Manea, P, Vidal, E, Coppere, B, Desmursclavel, H, Girard-Madoux, Mh, Hot, A, Ninet, J, Granel, B, Cohen, Jd, Keynote, A, Khau van Kien, A, Le Quellec, A, Riviere, S, Rullier, P, Bessis, D, Farcas, C, Bravetti, V, Moline, T, Wahl, D, Zuily, S, Granel-Brocard, F, Agard, C, Durant, C, Fuzibet, Jg, Queyrel, V, Berezne, A, Mouthon, L, Cabane, J, Tiev, K, Toledano, C, Lazareth, I, Michon-Pasturel, U, Priollet, P, Reguiai, Z, Cazaletslacoste, C, Jego, P, Letremy, A, Perlat, A, Duval-Modeste, Ab, Chatelus, E, Chiffot, H, Sibillia, J, Sordet, C, Adoue, D, Couret, B, Moulis, G, Pugnet, G, Sailler, L, Diot, E, Gaches, F, Farge, D, Keshtmand, H, Frances, C, von Elling, A, Bora, D, Ebel, J, Ahmadi-Simab, K, Klein, E, Hahn, K, Schulze, K, Rasche, C, Riemekasten, G, Lee, Hh, Deuschle, K, Mattat, K, Becker, M, Worm, M, Mensing, C, Klings, D, Mensing, H, Messall, J, Zuper, R, Eilbacher, P, Saar, P, Kaufmann, P, Hallermann, C, Schmidt, K, Wahn, H, Schildt, K, Schuart, T, Kaczmarczyk, A, Kellner, C, von Oelhafen, J, Baron von Bildering, P, Kunze, S, Kleiner, Hj, Alsheimer, B, Schuetz, N, Miirker-Hermann, E, Gottl, Kh, Weiss, E, Reischel, N, Kern, S, Goettl, Kh, Goetheuniversitiitsklinikum, Jw, Himsel, A, Henkemeier, U, Schwarting, A, Hazenbiller, A, Nichelmann, V, Rumbaur, C, Boesenberg, I, Schmeiser, T, Mueller-Ladner, U, Unholzer, A, Starz, H, Welzel, J, Plaumann, K, Stoeckl, F, Sperling, S, Podda, M, Wagner, N, Rapprich, H, Niedermeier, A, Messer, G, Sardy, M, Bekou, V, Dill-MUller, D, Wlodarz, M, Belloni, B, Huettig, B, Ziai, M, Hein, R, Kneitz, C, Federow, I, Schneider, K, Semmler, M, Hapke, S, Metzler, C, Stein, T, Enderlein, M, Kayser, M, Werthmann, M, Guenther, Cu, Neul, S, Hellmich, B, Loeffler, C, Pflugfelder, J, Karaenke, P, Mueglich, C, Tony, Hp, Marina, P, Popp, M, Mittag, M, Baumann, C, Scheib, Eg, Brand, H, Wilhelm, Hu, Bohm, J, Dyballa, J, Boehm, J, Taggeselle, J, Luthke, K, Wuerzburg, I, Niefanger, K, Mayer, L, Drabek, J, Harmuth, W, Dietl, S, Moritz, D, Gause, A, Gaubitz, M, Hallecker, A, Krupp, E, Rumpel, H, Moosig, F, Frey, P, Kahl, S, Linke, M, Merk, B, Bloching, Hh, Ochs, W, Kurthen, R, Eiden, E, Guertler, I, Aries, Pm, Kirchberg, S, Jahnke, K, Mettler, S, Toeller, S, Zwenger, S, Langer, He, Deininger, F, Hartmann, F, Neeck, G, Neek, G, Wernitzsch, H, Meier, L, Herr, U, Meier, U, Aaig, W, Bruckner, L, Sheikh, N, Wollenhaupt, J, Krog, B, Wollersdorfer, E, Hall, R, Diehm, C, Tiggers, C, Peters, J, Kirschke, J, Schroeder, Jo, Zeuner, R, Uhlig, S, Barth, S, Huegel, R, Glaeser, R, Schaefer, C, Monshausen, M, Mengden, T, Funkert, A, Blank, N, Lupaschko, S, Voss, B, Megahed, M, Sadeghlar, F, Seidel, M, Wasmuth, Jc, Kreuter, A, Vosswinkel, J, Pfoehler, C, Gerber, A, Haust, M, Hoff, Np, Mota, R, Akanay-Diesel, S, Homey, B, Katzemich, A, Erfurt-Berge, C, Sticherling, M, Beyer, C, Distler, J, Mitchell, A, Freundlieb, C, Rushentsova, U, Hermanns, G, Blaschke, S, Fiene, M, Wessel, C, Norgauer, J, Rabe, B, Schuster, J, Scholz, J, Kremer, K, Robakidze-Torbahn, M, Moinzadeh, P, Dohse, A, Muhlack, A, Schultz, L, Schult, S, Frambach, Y, Kruse, S, Kettenbach, A, Fell, I, Schweda, K, Steinbrink, K, Podobinska, M, Fieri beck, G, Schanz, S, Pfeiffer, C, Hassel, R, Herrgott, I, Sunderkoetter, C, Guenzel, J, Athanassiou, P, Dimitroulas, T, Settas, L, Kritikos, I, Tsifetaki, N, Garyfallos, A, Vasilopoulos, D, Boura, P, Kamali, S, Aslanidis, S, Vlachoyannopoulos, P, Galanopoulo, V, Sakkas, L, Koutroubas, A, Elezoglou, T, Galanopoulos, N, Grier, A, Murray, M, O'Rourke, M, Del Papa, N, Maglione, W, Zeni, S, Foti, R, Benenati, A, De Vita, S, Ferraccioli, G, Grassi, W, de Angeli, R, Pomponio, G, Mussi, A, Colonna, L, Airo, P, Zingarelli, S, Scorza, R, Serverino, A, Puppo, F, Negrini, S, Roma, I, Salsano, F, Triolo, G, Mazzuca, S, Carignola, R, Gatti, S, Lunardi, G, Riccieri, V, Salvarani, C, Bajocchi, G, Varcasia, G, Marasini, B, Belloll, L, de Luca, R, Stisi, S, Bellissimo, S, Fusaro, E, Pellerito, R, Cozzi, F, Rizzo, M, Bartoluzzi, A, Trotta, F, Cantatore, F, Corrado, A, Ferri, C, Colaci, M, Malavolta, N, Mule, R, Galeazzi, M, Lapadula, G, Mathieu, A, Vacca, A, Giacomelli, R, Cipriani, P, Montecucco, Cm, Codullo, V, Bucci, R, Battaglia, E, Valentini, G, Cuomo, G, Terlizzi, N, Serafino, L, Reumatologia, Uo, Bombardieri, S, Della Rossa, A, Doveri, M, Perricone, R, de Mattia, M, Pallotta, S, Groenendael, Jh, Seys, P, Goekoop, Rj, Han, Kh, Wlarvens, M, Bonte-Mineur, F, de Bois MH, de Beus WM, van Zeben, D, Vonk, M, Knaapen, Hk, Smit, A, Bootsma, H, Ton, E, Voskuyl, A, Dutmer, Ea, Stalk, Jn, Madland, Tm, Seip, M, Hoffmann Vold AM, Bitter, H, Stocklund Thomsen, R, Resende, C, Ponte, C, Martinho, S, Silva, F, Ferreira, P, Grilo, A, Riso, N, Santos, C, Camara, I, Costa, J, Alves, J, Oliveira, S, Almeida, I, Silva, I, Cordeiro, A, Coelho, P, Lukac, J, Dolnicar, As, Espinosa, G, Mejia, Jc, Ramos, M, Plasin Rodriguez MA, Mera, A, Blanco, Js, Diaz, Jj, Losada, L, Perez, E, Maneiro, Jr, Caamano, M, Fermindez, S, Insua, Sa, Barbado, J, Fonseca, Em, Nufio, Fj, Castellvi, I, Garcia de Ia Pena, P, Bellido, D, Paulino, M, Garcia, Pv, Salas, V, Minguez, Md, Sanchez, Ma, Urrego, C, Martin, I, Rueda, A, Calvo, J, Ripoll, Mm, Torres, Mc, Corteguera, M, Maceiras, F, Cruz, J, Mosquera, Ja, Gomez, R, Area, B, Carrio, I, Rubio, M, Castellvi Barranco, I, Santos, P, Simeon, Cp, Fonollosa, V, Egurbide, Mv, Garcia de Vicuna, R, Vicente, E, Villaverde, V, Fernandez, C, Garcia, E, Uson, J, Miguelez, R, Callejas, Jl, Ortego, N, Roman, J, Alegre-Sancho, Jj, Robles, A, Rios, Jj, Bonilla, Mg, Sanchez Andrade, A, Vazquez, Tr, Miranda, Ja, Saez, L, Zea, A, De la Puente, C, Martinez, Fg, Aguirre, Ma, Collado, P, Cruz, A, Crespo, M, Sanchez-Roman, J, Castillo, Mj, Garcia, Am, Muniz, G, Hedin, Pj, Stahl, C, Bracin, T, Nordin, A, Albertsson, K, Rydvald, Y, Thorsson, C, Hermansson, E, Maurer, B, Verner, D, Schmidt Bosshard, R, Hall, F, Murphy, K, Lamb, J, Anderson, M, Moots, R, Buch, M, Bissell, L, Madhok, R, Hampson, R, D'Cruz, D, Choong, Lm, Gordon, P, Dobson, J, Salerno, R, Nisar, M, Williams, C, Wilcox, L, Denton, C, Ochiel, R, Ngcozana, T, Parker, L, Vincent, R, Mchugh, N, Cole, S, Brown, S, James, J, Herrick, A, Manning, J, Moore, T, Faizal, A, Skyes, H, Smythe, A, Hamilton, A.

المساهمون: L., Guillevin, E., Hunsche, C. P., Denton, T., Krieg, B., Schwierin, D., Rosenberg, DUO Registry Group: B Raffier, Matucci-Cerinic M., Hirschi, M, Trautinger, F, Schmidt, P, Stetter, M, Hundstorfer, M, Reinhart, V, Monshi, B, Pirkhammer, D, Richter, L, Hamberger, N, Metz, S, Feldmann, R, Semmelweis, K, Lackner, K, Tomi, N, Kolle, H, Hafner, F, Brodmann, M, Kuen-Spiegel, M, Minmair, G, M Heil, P, Broil, H, Holzer, G, Illmer, X, Rintelen, B, Sautner, J, Takacs, M, Thun, M, Zemanova, I, Soukup, T, Smrzova, A, Bohmova, J, Prochazkova, L, Nemec, P, Fojtik, Z, Suchy, D, Becvar, R, B Olsen, A, H Sondergaard, K, Luosu jarvi, R, Vidqvist, K-L, Madaule, S, Beneton, N, Maillard, H, Charlanne, H, Granelbrocard, F, Hachulla, E, Y Hatron, P, Jourdain, N, Lambert, M, Launay, D, Morell, S, Woijtasik, G, Skowron, F, Zenone, T, Dadban, A, Lok, C, Ferrandiz, D, Magybertrand, N, P Moiton, M, Taieb, A, Balquiere, S, Belin, E, Droitcourt, C, Julien, S, Prey, S, Boulon, C, Constans, J, S Doutre, M, Kostrzwewa, E, Richez, C, Greco, M, Misery, L, Sassolas, B, Collet, E, Berthier, S, Leguy-Seguin, V, Imbert, B, Carpentier, P, Blaise, S, Couraud, A, Doeffel-Hantz, V, Spars, A, Bezanahary, H, Boussely, N, Dumonteil, S, L Fauchais, A, Goudran, G, Loustaud-Ratti, V, Manea, P, Vidal, E, Coppere, B, Desmursclavel, H, H Girard-Madoux, M, Hot, A, Ninet, J, Granel, B, D Cohen, J, Keynote, A, Khau van Kien, A, Le Quellec, A, Riviere, S, Rullier, P, Bessis, D, Farcas, C, Bravetti, V, Moline, T, Wahl, D, Zuily, S, Granel-Brocard, F, Agard, C, Durant, C, G Fuzibet, J, Queyrel, V, Berezne, A, Guillevin, L, Mouthon, L, Cabane, J, Tiev, K, Toledano, C, Lazareth, I, Michon-Pasturel, U, Priollet, P, Reguiai, Z, Cazaletslacoste, C, Jego, P, Letremy, A, Perlat, A, B Duval-Modeste, A, Chatelus, E, Chiffot, H, Sibillia, J, Sordet, C, Adoue, D, Couret, B, Moulis, G, Pugnet, G, Sailler, L, Diot, E, Gaches, F, Farge, D, Keshtmand, H, Frances, C, von Elling, A, Bora, D, Ebel, J, Ahmadi-Simab, K, Klein, E, Hahn, K, Schulze, K, Rasche, C, Riemekasten, G, H Lee, H, Deuschle, K, Mattat, K, Becker, M, Worm, M, Mensing, C, Klings, D, Mensing, H, Messall, J, Zuper, R, Eilbacher, P, Saar, P, Kaufmann, P, Hallermann, C, Schmidt, K, Wahn, H, Schildt, K, Schuart, T, Kaczmarczyk, A, Kellner, C, von Oelhafen, J, Baron von Bildering, P, Kunze, S, J Kleiner, H, Alsheimer, B, Schuetz, N, Miirker-Hermann, E, Gottl, K-H, Weiss, E, Reischel, N, Kern, S, H Goettl, K, Goetheuniversitiitsklinikum, J-W, Himsel, A, Henkemeier, U, Schwarting, A, Hazenbiller, A, Nichelmann, V, Rumbaur, C, Boesenberg, I, Schmeiser, T, Mueller-Ladner, U, Unholzer, A, Starz, H, Welzel, J, Plaumann, K, Stoeckl, F, Sperling, S, Podda, M, Wagner, N, Rapprich, H, Niedermeier, A, Messer, G, Sardy, M, Bekou, V, Dill-MUller, D, Wlodarz, M, Belloni, B, Huettig, B, Ziai, M, Hein, R, Kneitz, C, Federow, I, Schneider, K, Semmler, M, Hapke, S, Metzler, C, Stein, T, Enderlein, M, Kayser, M, Werthmann, M, U Guenther, C, Neul, S, Hellmich, B, Loeffler, C, Pflugfelder, J, Karaenke, P, Mueglich, C, P Tony, H, Marina, P, Popp, M, Mittag, M, Baumann, C, G Scheib, E, Brand, H, U Wilhelm, H, Bohm, J, Dyballa, J, Boehm, J, Taggeselle, J, Luthke, K, Wuerzburg, I, Niefanger, K, Mayer, L, Drabek, J, Harmuth, W, Dietl, S, Moritz, D, Gause, A, Gaubitz, M, Hallecker, A, Krupp, E, Rumpel, H, Moosig, F, Frey, P, Kahl, S, Linke, M, Merk, B, H Bloching, H, Ochs, W, Kurthen, R, Eiden, E, Guertler, I, M Aries, P, Kirchberg, S, Jahnke, K, Mettler, S, Toeller, S, Zwenger, S, E Langer, H, Deininger, F, Hartmann, F, Neeck, G, Neek, G, Wernitzsch, H, Meier, L, Herr, U, Meier, U, Aaig, W, Bruckner, L, Sheikh, N, Wollenhaupt, J, Krog, B, Wollersdorfer, E, Hall, R, Diehm, C, Tiggers, C, Peters, J, Kirschke, J, O Schroeder, J, Zeuner, R, Uhlig, S, Barth, S, Huegel, R, Glaeser, R, Schaefer, C, Monshausen, M, Mengden, T, Funkert, A, Blank, N, Lupaschko, S, Voss, B, Megahed, M, Sadeghlar, F, Seidel, M, C Wasmuth, J, Kreuter, A, Vosswinkel, J, Pfoehler, C, Gerber, A, Haust, M, P Hoff, N, Mota, R, Akanay-Diesel, S, Homey, B, Katzemich, A, Erfurt-Berge, C, Sticherling, M, Beyer, C, Distler, J, Mitchell, A, Freundlieb, C, Rushentsova, U, Hermanns, G, Blaschke, S, Fiene, M, Wessel, C, Norgauer, J, Rabe, B, Schuster, J, Scholz, J, Kremer, K, Robakidze-Torbahn, M, Moinzadeh, P, Dohse, A, Muhlack, A, Schultz, L, Schult, S, Frambach, Y, Kruse, S, Kettenbach, A, Fell, I, Schweda, K, Steinbrink, K, Podobinska, M, Fieri beck, G, Schanz, S, Pfeiffer, C, Hassel, R, Herrgott, I, Sunderkoetter, C, Guenzel, J, Athanassiou, P, Dimitroulas, T, Settas, L, Kritikos, I, Tsifetaki, N, Garyfallos, A, Vasilopoulos, D, Boura, P, Kamali, S, Aslanidis, S, Vlachoyannopoulos, P, Galanopoulo, V, Sakkas, L, Koutroubas, A, Elezoglou, T, Galanopoulos, N, Grier, A, Murray, M, O'Rourke, M, Del Papa, N, Maglione, W, Zeni, S, Foti, R, Benenati, A, De Vita, S, Ferraccioli, G, Grassi, W, de Angeli, R, Pomponio, G, Mussi, A, Colonna, L, Airo, P, Zingarelli, S, Scorza, R, Serverino, A, Puppo, F, Negrini, S, Roma, I, Salsano, F, Triolo, G, Mazzuca, S, Carignola, R, Gatti, S, Lunardi, G, Riccieri, V, Salvarani, C, Bajocchi, G, Varcasia, G, Marasini, B, Belloll, L, Matucci-Cerinic, M, de Luca, R, Stisi, S, Bellissimo, S, Fusaro, E, Pellerito, R, Cozzi, F, Rizzo, M, Bartoluzzi, A, Trotta, F, Cantatore, F, Corrado, A, Ferri, C, Colaci, M, Malavolta, N, Mule, R, Galeazzi, M, Lapadula, G, Mathieu, A, Vacca, A, Giacomelli, R, Cipriani, P, M Montecucco, C, Codullo, V, Bucci, R, Battaglia, E, Valentini, G, Cuomo, G, Terlizzi, N, Serafino, L, O Reumatologia, U, Bombardieri, S, Della Rossa, A, Doveri, M, Perricone, R, de Mattia, M, Pallotta, S, M Groenendael, J H L, Seys, P, J Goekoop, R, H Han, K, Wlarvens, M, Bonte-Mineur, F, W de Bois, M H

المصدر: Europe PubMed Central
Web of Science
ResearcherID

مصطلحات موضوعية: Adult, Employment, Male, Registrie, Scleroderma, Systemic, Systemic, Middle Aged, Scleroderma, Fingers, Disability Evaluation, Cost of Illness, Skin Ulcer, Activities of Daily Living, Finger, Humans, Female, Registries, Self Report, Human

الوصف: Digital ulcers (DUs) are frequent manifestations of systemic scleroderma (SSc). This study assessed functional limitations due to DUs among patients enrolled in the Digital Ulcer Outcome (DUO) Registry, an international, multicentre, observational registry of SSc patients with DU disease.Patients completed at enrolment a DU-specific functional assessment questionnaire with a 1-month recall period, measuring impairment in work and daily activities, and hours of help needed from others. Physician-reported clinical parameters were used to describe the population. For patients who completed at least part of the questionnaire, descriptive analyses were performed for overall results, and stratified by number of DUs at enrolment.This study included 2327 patients who completed at least part of the questionnaire. For patients with 0, 1-2, and ≥3 DUs at enrolment, mean overall work impairment during the prior month among employed/self-employed patients was 28%, 42%, and 48%, respectively. Across all included patients, ability to perform daily activities was impaired on average by 35%, 54%, and 63%, respectively. Patients required a mean of 2.0, 8.7, and 8.8 hours of paid help and 17.0, 35.9, and 63.7 hours of unpaid help, respectively, due to DUs in the prior month. Patients with DUs had more complications and medication use than patients with no DUs.With increasing number of DUs, SSc patients reported more impairment in work and daily activities and required more support from others.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::36b38d094db92bf9ef75895b4f85d02eTest
http://europepmc.org/abstract/med/23910613Test