دورية أكاديمية
Evaluation of Ideal Extent of Corpus Callosotomy Based on the Location of Intracallosal Motor Fibers
| العنوان: | Evaluation of Ideal Extent of Corpus Callosotomy Based on the Location of Intracallosal Motor Fibers |
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| المؤلفون: | Küçükyürük, Barış, Uzan, Mustafa, Avyasov, Rashid, Tahmazoğlu, Burak, İşler, Cihan, Sanus, Galip Zihni, Tanrıöver, Necmettin |
| المساهمون: | İÜC, Cerrahpaşa Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü |
| بيانات النشر: | Elsevier Inc. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Corpus callosotomy, Corpus callosum, Epilepsy surgery, Fiber dissection, Microsurgical anatomy, White matter tracts |
| الوصف: | PubMed: 32916363 ; Background: The corpus callosotomy (CCT) has been reported as an effective procedure to alleviate drop attacks. However, the extent of CCT remains debatable. Classical studies suggest that motor fibers traverse mainly through the anterior half of the corpus callosum (CC), although recent diffusion tensor imaging studies described that motor fibers crossed the CC in a more posterior location, emphasizing the posterior midbody and the isthmus. Methods: Cortical and subcortical structures were examined in 30 hemispheres prepared for white matter fiber dissection. Dissections were carried out under surgical magnification to trace fibers originating from the primary motor cortex and their course through the CC. The distance of the most anterior and posterior motor fibers to the tip of the genu were measured, and the extent of CCT enabling disconnection of all motor fibers was calculated. Results: Motor fibers coursed through the posterior half of the CC in the majority of hemispheres, mainly locating in posterior midbody and the isthmus. Callosal fibers should be interrupted to an average of 61% ± 0.07% point of the CC to reach the anterior limit of motor fibers and to an average of 69% ± 0.07% point to include posterior limit of motor fibers. Motor fibers were extending until the posterior one third of the CC in 22 specimens. Conclusions: Anterior-half CCT did not include all motor fibers in any specimen. Anterior two thirds CCT disrupted all motor fibers in one fourth of the cases. Our findings suggest that an ideal CCT should extend to the posterior midbody and isthmus of the CC. © 2020 Elsevier Inc. ; Conflict of interest statement: The authors declare that the article content was composed in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1878-8750 |
| العلاقة: | World Neurosurgery; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.1016/j.wneu.2020.09.006Test; https://hdl.handle.net/20.500.12831/2169Test |
| DOI: | 10.1016/j.wneu.2020.09.006 |
| الإتاحة: | https://doi.org/10.1016/j.wneu.2020.09.006Test https://doi.org/20.500.12831/2169Test https://hdl.handle.net/20.500.12831/2169Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.7D1F46C5 |
| قاعدة البيانات: | BASE |
| تدمد: | 18788750 |
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| DOI: | 10.1016/j.wneu.2020.09.006 |