Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

التفاصيل البيبلوغرافية
العنوان: Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study
المؤلفون: Eyre, DW, Lumley, SF, O'Donnell, D, Campbell, M, Sims, E, Lawson, E, Warren, F, James, T, Cox, S, Howarth, A, Doherty, G, Hatch, SB, Kavanagh, J, Chau, KK, Fowler, PW, Swann, J, Volk, D, Yang-Turner, F, Stoesser, N, Matthews, PC, Dudareva, M, Davies, T, Shaw, RH, Peto, L, Downs, LO, Vogt, A, Amini, A, Young, BC, Drennan, PG, Mentzer, AJ, Skelly, DT, Karpe, F, Neville, MJ, Andersson, M, Brent, AJ, Jones, N, Martins Ferreira, L, Christott, T, Marsden, BD, Hoosdally, S, Cornall, R, Crook, DW, Stuart, DI, Screaton, G, Group, Oxford University Hospitals Staff Testing, Watson, AJ, Taylor, A, Chetwynd, A, Grassam-Rowe, A, Mighiu, AS, Peck, LJ, Ebner, D, Conlon, CP
المصدر: eLife, Vol 9 (2020)
eLife
بيانات النشر: eLife Sciences Publications, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Male, 0301 basic medicine, serology, law.invention, 0302 clinical medicine, law, Surveys and Questionnaires, Health care, Epidemiology, Medicine, risk factors, 030212 general & internal medicine, Young adult, Biology (General), Asymptomatic Infections, Incidence, General Neuroscience, Incidence (epidemiology), Age Factors, General Medicine, Middle Aged, Intensive care unit, Virus, 3. Good health, Intensive Care Units, Female, medicine.symptom, Coronavirus Infections, Covid-19, Research Article, Adult, Risk, medicine.medical_specialty, Infectious Disease Transmission, Patient-to-Professional, Adolescent, QH301-705.5, Health Personnel, Science, Pneumonia, Viral, 030106 microbiology, Asymptomatic, General Biochemistry, Genetics and Molecular Biology, Betacoronavirus, Young Adult, 03 medical and health sciences, Humans, Hospitals, Teaching, Pandemics, Aged, General Immunology and Microbiology, business.industry, SARS-CoV-2, healthcare workers, Odds ratio, United Kingdom, Epidemiology and Global Health, Family medicine, symptoms, Observational study, business
الوصف: We conducted voluntary Covid-19 testing programmes for symptomatic and asymptomatic staff at a UK teaching hospital using naso-/oro-pharyngeal PCR testing and immunoassays for IgG antibodies. 1128/10,034 (11.2%) staff had evidence of Covid-19 at some time. Using questionnaire data provided on potential risk-factors, staff with a confirmed household contact were at greatest risk (adjusted odds ratio [aOR] 4.82 [95%CI 3.45–6.72]). Higher rates of Covid-19 were seen in staff working in Covid-19-facing areas (22.6% vs. 8.6% elsewhere) (aOR 2.47 [1.99–3.08]). Controlling for Covid-19-facing status, risks were heterogenous across the hospital, with higher rates in acute medicine (1.52 [1.07–2.16]) and sporadic outbreaks in areas with few or no Covid-19 patients. Covid-19 intensive care unit staff were relatively protected (0.44 [0.28–0.69]), likely by a bundle of PPE-related measures. Positive results were more likely in Black (1.66 [1.25–2.21]) and Asian (1.51 [1.28–1.77]) staff, independent of role or working location, and in porters and cleaners (2.06 [1.34–3.15]).
اللغة: English
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c76f76de4fc9e67f727b32ee73b4152Test
https://doi.org/10.7554/elife.60675Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....6c76f76de4fc9e67f727b32ee73b4152
قاعدة البيانات: OpenAIRE