دورية أكاديمية

Heparin binding EGF is necessary for vasospastic response to endothelin.

التفاصيل البيبلوغرافية
العنوان: Heparin binding EGF is necessary for vasospastic response to endothelin.
المؤلفون: Chansel, Dominique1,2,3, Ciroldi, Magali1,2,3, Vandermeersch, Sophie1,2,3, Jackson, Leslie F.4, Gomez, Ana-Maria5,6,7, Henrion, Daniel8,9, Lee, David C.4, Coffman, Thomas M.10, Richard, Sylvain5,6,7, Dussaule, Jean-Claude1,2,3,11, Tharaux, Pierre-Louis1,2,3 pierre-louis.tharaux@tnn.aphp.fr
المصدر: FASEB Journal. Sep2006, Vol. 20 Issue 11, p1936-1938. 3p. 1 Diagram, 2 Graphs.
مصطلحات موضوعية: *HEPARIN, *CORONARY vasospasm, *ENDOTHELINS, *ARTERIES, *CALCIUM, *VASCULAR smooth muscle
مستخلص: This article presents a study on the role of heparin binding (HB) EGF in the vasospastic response to endothelin (ET-1). Changes in the vasocontractile response to endothelin of HB-EGF-deficient arteries are described. The role of PI3K-kinase on the ET-1-induced increase in calcium mobilization in vascular smooth muscle cells is discussed. Conclusions of the study are given.
قاعدة البيانات: Academic Search Index
الوصف
تدمد:08926638
DOI:10.1096/fj.05-5328fje