دورية أكاديمية

Chronic Airways Assessment Test : psychometric properties in patients with asthma and/or COPD

التفاصيل البيبلوغرافية
العنوان: Chronic Airways Assessment Test : psychometric properties in patients with asthma and/or COPD
المؤلفون: Tomaszewski, Erin L., Atkinson, Mark J., Janson, Christer, Karlsson, Niklas, Make, Barry, Price, David, Reddel, Helen K., Vogelmeier, Claus F., Müllerová, Hana, Jones, Paul W.
بيانات النشر: Uppsala universitet, Lung- allergi- och sömnforskning
AstraZeneca, BioPharmaceut Med, 1 Medimmune Way, Gaithersburg, MD 20878 USA.
Evidera, Bethesda, MD USA.
AstraZeneca, BioPharmaceut Med, Gothenburg, Sweden.
Natl Jewish Hlth, Denver, CO USA.;Univ Colorado, Denver, CO USA.
Observat & Pragmat Res Inst, Singapore, Singapore.;Univ Aberdeen, Ctr Acad Primary Care, Div Appl Hlth Sci, Aberdeen, Scotland.
Univ Sydney, Woolcock Inst Med Res, Sydney, NSW, Australia.
Univ Marburg, German Ctr Lung Res DZL, Dept Med Pulm & Crit Care Med, Marburg, Germany.
AstraZeneca, BioPharmaceut Med, Cambridge, England.
GlaxoSmithKline, Global Resp Franchise, Brentford, Middx, England.
سنة النشر: 2023
المجموعة: Uppsala University: Publications (DiVA)
مصطلحات موضوعية: Asthma, COPD, Patient-reported, Psychometrics, Chronic Airways Assessment Test, COPD Assessment Test, Respiratory Medicine and Allergy, Lungmedicin och allergi
الوصف: Background: No short patient-reported outcome (PRO) instruments assess overall health status across different obstructive lung diseases. Thus, the wording of the introduction to the Chronic Obstructive Pulmonary Disease (COPD) Assessment Test (CAT) was modified to permit use in asthma and/or COPD. This tool is called the Chronic Airways Assessment Test (CAAT). Methods: The psychometric properties of the CAAT were evaluated using baseline data from the NOVELTY study (NCT02760329) in patients with physician-assigned asthma, asthma + COPD or COPD. Analyses included exploratory/confirmatory factor analyses, differential item functioning and analysis of construct validity. Responses to the CAAT and CAT were compared in patients with asthma + COPD and those with COPD. Results: CAAT items were internally consistent (Cronbach's alpha: > 0.7) within each diagnostic group (n = 510). Models for structural and measurement invariance were strong. Tests of differential item functioning showed small differences between asthma and COPD in individual items, but these were not consistent in direction and had minimal overall impact on the total score. The CAAT and CAT were highly consistent when assessed in all NOVELTY patients who completed both (N = 277, Pearson's correlation coefficient: 0.90). Like the CAT itself, CAAT scores correlated moderately (0.4-0.7) to strongly (> 0.7) with other PRO measures and weakly (< 0.4) with spirometry measures. Conclusions: CAAT scores appear to reflect the same health impairment across asthma and COPD, making the CAAT an appropriate PRO instrument for patients with asthma and/or COPD. Its brevity makes it suitable for use in clinical studies and routine clinical practice.Trial registration: NCT02760329.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
العلاقة: Respiratory Research, 1465-9921, 2023, 24; orcid:0000-0001-5093-6980; orcid:0000-0002-6695-6350; http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-503651Test; PMID 37031164; ISI:000967456300002
DOI: 10.1186/s12931-023-02394-6
الإتاحة: https://doi.org/10.1186/s12931-023-02394-6Test
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-503651Test
حقوق: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.C7BEDBF
قاعدة البيانات: BASE