دورية أكاديمية
Event rates and incidence of post-COVID-19 condition in hospitalised SARS-CoV-2 positive children and young people and controls across different pandemic waves: exposure-stratified prospective cohort study in Moscow (StopCOVID)
| العنوان: | Event rates and incidence of post-COVID-19 condition in hospitalised SARS-CoV-2 positive children and young people and controls across different pandemic waves: exposure-stratified prospective cohort study in Moscow (StopCOVID) |
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| المؤلفون: | Pazukhina, Ekaterina, Rumyantsev, Mikhail, Baimukhambetova, Dina, Bondarenko, Elena, Markina, Nadezhda, El-Taravi, Yasmin, Petrova, Polina, Ezhova, Anastasia, Andreeva, Margarita, Iakovleva, Ekaterina, Bobkova, Polina, Pikuza, Maria, Trefilova, Anastasia, Abdeeva, Elina, Galiautdinova, Aysylu, Filippova, Yulia, Bairashevskaia, Anastasiia, Zolotarev, Aleksandr, Bulanov, Nikolay, DunnGalvin, Audrey, Chernyavskaya, Anastasia, Kondrikova, Elena, Kolotilina, Anastasia, Gadetskaya, Svetlana, Ivanova, Yulia V, Turina, Irina, Eremeeva, Alina, Fedorova, Ludmila A, Comberiati, Pasquale, Peroni, Diego G, Nekliudov, Nikita, Genuneit, Jon, Reyes, Luis Felipe, Brackel, Caroline L H, Mazankova, Lyudmila, Miroshina, Alexandra, Samitova, Elmira, Borzakova, Svetlana, Carson, Gail, Sigfrid, Louise, Scott, Janet T, McFarland, Sammie, Greenhawt, Matthew, Buonsenso, Danilo, Semple, Malcolm G, Warner, John O, Olliaro, Piero, Osmanov, Ismail M, Korsunskiy, Anatoliy A, Munblit, Daniel |
| المساهمون: | Pazukhina, Ekaterina, Rumyantsev, Mikhail, Baimukhambetova, Dina, Bondarenko, Elena, Markina, Nadezhda, El-Taravi, Yasmin, Petrova, Polina, Ezhova, Anastasia, Andreeva, Margarita, Iakovleva, Ekaterina, Bobkova, Polina, Pikuza, Maria, Trefilova, Anastasia, Abdeeva, Elina, Galiautdinova, Aysylu, Filippova, Yulia, Bairashevskaia, Anastasiia, Zolotarev, Aleksandr, Bulanov, Nikolay, Dunngalvin, Audrey, Chernyavskaya, Anastasia, Kondrikova, Elena, Kolotilina, Anastasia, Gadetskaya, Svetlana, Ivanova, Yulia V, Turina, Irina, Eremeeva, Alina, Fedorova, Ludmila A, Comberiati, Pasquale, Peroni, Diego G, Nekliudov, Nikita, Genuneit, Jon, Reyes, Luis Felipe, Brackel, Caroline L H, Mazankova, Lyudmila, Miroshina, Alexandra, Samitova, Elmira, Borzakova, Svetlana, Carson, Gail, Sigfrid, Louise, Scott, Janet T, Mcfarland, Sammie, Greenhawt, Matthew, Buonsenso, Danilo, Semple, Malcolm G, Warner, John O, Olliaro, Piero, Osmanov, Ismail M, Korsunskiy, Anatoliy A, Munblit, Daniel |
| سنة النشر: | 2024 |
| المجموعة: | ARPI - Archivio della Ricerca dell'Università di Pisa |
| مصطلحات موضوعية: | COVID-19, COVID-19 sequelae, Children, Controlled study, Incidence, Long COVID, PASC, Post COVID-19 condition, Post-acute sequelae of SARS-CoV-2 infection |
| الوصف: | BackgroundLong-term health outcomes in children and young people (CYP) after COVID-19 infection are not well understood and studies with control groups exposed to other infections are lacking. This study aimed to investigate the incidence of post-COVID-19 condition (PCC) and incomplete recovery in CYP after hospital discharge and compare outcomes between different SARS-CoV-2 variants and non-SARS-CoV-2 infections.MethodsA prospective exposure-stratified cohort study of individuals under 18 years old in Moscow, Russia. Exposed cohorts were paediatric patients admitted with laboratory-confirmed COVID-19 infection between April 2 and December 11, 2020 (Wuhan variant cohort) and between January 12 and February 19, 2022 (Omicron variant cohort). CYP admitted with respiratory and intestinal infections, but negative lateral flow rapid diagnostic test and PCR-test results for SARS-CoV-2, between January 12 and February 19, 2022, served as unexposed reference cohort. Comparison between the 'exposed cohorts' and 'reference cohort' was conducted using 1:1 matching by age and sex. Follow-up data were collected via telephone interviews with parents, utilising the long COVID paediatric protocol and survey developed by the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC). The WHO case definition was used to categorise PCC.ResultsOf 2595 CYP with confirmed COVID-19, 1707 (65.7%) participated in follow-up interviews, with 1183/1707 (69%) included in the final 'matched' analysis. The median follow-up time post-discharge was 6.7 months. The incidence of PCC was significantly higher in the Wuhan variant cohort (89.7 cases per 1000 person-months, 95% CI 64.3-120.3) compared to post-infection sequalae in the reference cohort (12.2 cases per 1000 person-months, 95% CI 4.9-21.9), whereas the difference with the Omicron variant cohort and reference cohort was not significant. The Wuhan cohort had higher incidence rates of dermatological, fatigue, gastrointestinal, sensory, and sleep manifestations, as ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/38302974; info:eu-repo/semantics/altIdentifier/wos/WOS:001155075100001; volume:22; issue:1; firstpage:48; journal:BMC MEDICINE; https://hdl.handle.net/11568/1224927Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85183730455 |
| DOI: | 10.1186/s12916-023-03221-x |
| الإتاحة: | https://doi.org/10.1186/s12916-023-03221-xTest https://hdl.handle.net/11568/1224927Test |
| رقم الانضمام: | edsbas.24BF9F1A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s12916-023-03221-x |
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