التفاصيل البيبلوغرافية
| العنوان: |
Post-Pulmonary Embolism Impairment Six Months after Acute Pulmonary Embolism: A Prospective Registry. |
| المؤلفون: |
Alizadehasl, Azin, Farrashi, Melody, Naghsbandi, Mona, Khansari, Nakisa, Moosavi, Jamal, Shafe, Omid, Mohebbi, Bahram, Bakhshandeh, Hooman, Pouraliakbar, Hamid Reza, Rezaei-Kalantari, Kiara, Naghavi, Batoul, Talakoob, Hamed, Mohseni Salehi, Maryam, Kaviani, Raheleh, Amin, Ahmad, Barco, Stefano, Sadeghipour, Parham |
| المصدر: |
Vascular & Endovascular Surgery; Oct2023, Vol. 57 Issue 7, p665-672, 8p |
| مصطلحات موضوعية: |
ECHOCARDIOGRAPHY, REPORTING of diseases, PULMONARY embolism, CONFIDENCE intervals, TRICUSPID valve diseases, FUNCTIONAL status, TREATMENT effectiveness, DIAGNOSTIC imaging, RIGHT ventricular dysfunction, DESCRIPTIVE statistics, THREE-dimensional printing, ACUTE diseases, LONGITUDINAL method, DISEASE complications |
| مستخلص: |
Background: Little evidence is available on post-pulmonary embolism impairment (PPEI), a recently defined complication of pulmonary embolism (PE) encompassing dysfunctional clinical and imaging parameters. In the present study, we sought to evaluate its frequency with a focus on the main components. Methods: In this prospective registry, we included patients with a confirmed diagnosis of acute PE and focused on those with initial right ventricular (RV) dysfunction. Their baseline, pre-discharge, and 6 month follow-up clinical and imaging characteristics were recorded. The main study outcomes were incomplete RV functional recovery, exercise capacity limitations (based on the 6 minute walk test), and their combination, which defines PPEI, within six months of acute PE. Results: Of 170 consecutive patients with a confirmed diagnosis of acute PE, 123 accepted to participate in the follow-up study, of whom 87 had initial RV dysfunction. The 6 month rates of incomplete RV functional recovery, signs of an intermediate-to-high echocardiographic probability of PH, and exercise limitations were observed in 58.6, 32.1, and 45.9%, respectively. A total of 22 (25.2%; 95% CI 15.5-34.4%) patients had PPEI. The RV/LV ratio and the fractional area change on discharge after acute PE were more often impaired among patients with incomplete RV recovery, exercise limitations, and a high probability of PH at 6 months. In contrast, an initial impaired RV diastolic function indices appeared to characterize patients with a limited exercise capacity at 6 months. Discussion: PPEI affects one fourth of patients surviving acute PE with half of them presenting with RV dysfunction or exercise limitations. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
