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A pragmatic approach to estimating average treatment effects from EHR data: the effect of prone positioning on mechanically ventilated COVID-19 patients

التفاصيل البيبلوغرافية
العنوان: A pragmatic approach to estimating average treatment effects from EHR data: the effect of prone positioning on mechanically ventilated COVID-19 patients
المؤلفون: Izdebski, Adam, Thoral, Patrick J., Lalisang, Robbert C. A., McHugh, Dean M., Gommers, Diederik, Cremer, Olaf L., Bosman, Rob J., Rigter, Sander, Wils, Evert-Jan, Frenzel, Tim, Dongelmans, Dave A., de Jong, Remko, Peters, Marco A. A., Kamps, Marlijn J. A, Ramnarain, Dharmanand, Nowitzky, Ralph, Nooteboom, Fleur G. C. A., de Ruijter, Wouter, Urlings-Strop, Louise C., Smit, Ellen G. M., Mehagnoul-Schipper, D. Jannet, Dormans, Tom, de Jager, Cornelis P. C., Hendriks, Stefaan H. A., Achterberg, Sefanja, Oostdijk, Evelien, Reidinga, Auke C., Festen-Spanjer, Barbara, Brunnekreef, Gert B., Cornet, Alexander D., Tempel, Walter van den, Boelens, Age D., Koetsier, Peter, Lens, Judith, Faber, Harald J., Karakus, A., Entjes, Robert, de Jong, Paul, Rettig, Thijs C. D., Arbous, Sesmu, Fleuren, Lucas M., Dam, Tariq A., Tonutti, Michele, de Bruin, Daan P., Elbers, Paul W. G., Cinà, Giovanni
سنة النشر: 2021
المجموعة: Computer Science
مصطلحات موضوعية: Computer Science - Machine Learning, Computer Science - Artificial Intelligence
الوصف: Despite the recent progress in the field of causal inference, to date there is no agreed upon methodology to glean treatment effect estimation from observational data. The consequence on clinical practice is that, when lacking results from a randomized trial, medical personnel is left without guidance on what seems to be effective in a real-world scenario. This article proposes a pragmatic methodology to obtain preliminary but robust estimation of treatment effect from observational studies, to provide front-line clinicians with a degree of confidence in their treatment strategy. Our study design is applied to an open problem, the estimation of treatment effect of the proning maneuver on COVID-19 Intensive Care patients.
نوع الوثيقة: Working Paper
الوصول الحر: http://arxiv.org/abs/2109.06707Test
رقم الانضمام: edsarx.2109.06707
قاعدة البيانات: arXiv
الوصف
الوصف غير متاح.