دورية أكاديمية

Collateral Scores and Outcomes after Endovascular Treatment for Basilar Artery Occlusion.

التفاصيل البيبلوغرافية
العنوان: Collateral Scores and Outcomes after Endovascular Treatment for Basilar Artery Occlusion.
المؤلفون: Antunes Dias, Francisco1 (AUTHOR) franciscodias.neuro@usp.br, Castro-Afonso, Luis Henrique2 (AUTHOR), Zanon Zotin, Maria Clara2 (AUTHOR), Alessio-Alves, Frederico Fernandes1 (AUTHOR), Martins Filho, Rui Kleber do Vale1 (AUTHOR), Camilo, Millene Rodrigues1 (AUTHOR), Nakiri, Guilherme Seizem2 (AUTHOR), Abud, Daniel Giansante2 (AUTHOR), Pontes-Neto, Octavio Marques1 (AUTHOR)
المصدر: Cerebrovascular Diseases. 2019, Vol. 47 Issue 5/6, p285-290. 6p. 2 Charts, 2 Graphs.
مصطلحات موضوعية: *BASILAR artery, *COLLATERAL circulation, *UNIVARIATE analysis, *COMPUTED tomography, *MULTIVARIATE analysis
مصطلحات جغرافية: BRAZIL
مستخلص: Background: Basilar artery occlusion (BAO) is a rare stroke subtype with high mortality rates. Best BAO reperfusion strategy is still controversial. Objective: We aim to describe outcomes of BAO patients submitted to mechanical thrombectomy (MT) in a comprehensive stroke center in Brazil and analyze which previous published computed tomography angiography (CTA) collateral score better predict functional outcomes. Methods: Retrospective analysis of consecutive BAO patients. CTA was used to evaluate the posterior circulation collateral score (PC-CS), the basilar artery on CTA score, and for the presence of posterior communicating arteries. A favorable outcome was defined as modified Rankin Score ≤3 at 90-days. After univariate analyses, multivariate logistic regression was used to identify if any collateral score independently predicts favorable outcomes. Results: Between January 2011 and April 2017, 27 (85% male) BAO patients with median NIHSS 26 (IQR 15–32) were identified. Twenty-five (93%) patients were treated with MT devices, and only 2 (7%) patients were treated with angioplasty and stenting. Successful recanalization rate was 85%, and only 1 (3.7%) patient had symptomatic hemorrhagic transformation. Favorable outcomes were reached in 10 (37%) patients. In univariate analysis, female sex, NIHSS, Glasgow coma scale, mild-to-moderate symptoms on admission, onset-to-groin time, and PC-CS predicted favorable outcomes. In multivariate analysis, PC-CS (OR 1.69; 95% CI 1.10–2.60; p = 0.016) and NIHSS (OR 0.84; 95% CI 0.77–0.93; p = 0.001) remained the only independent predictors of favorable outcomes. The PC-CS AUC was 0.80 (95% CI 0.62–0.98; p = 0.012). Conclusions: MT is a promising strategy for BAO treatment. Among collateral scores, PC-CS was the only independent predictor of favorable outcomes in the present study. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:10159770
DOI:10.1159/000502083