التفاصيل البيبلوغرافية
العنوان: |
Composite lymphoma with relapse of enteropathy-type T-cell lymphoma. |
المؤلفون: |
Du, Zunguo1 (AUTHOR), Chen, Jieqing2 (AUTHOR), Zhou, Xiaoyan3 (AUTHOR), Zhang, Taiming3 (AUTHOR), Chen, Bobin4 (AUTHOR), Tang, Feng1 (AUTHOR) tangfeng519@sohu.com |
المصدر: |
Leukemia & Lymphoma. May2009, Vol. 50 Issue 5, p749-756. 8p. 5 Color Photographs, 1 Chart. |
مصطلحات موضوعية: |
*LYMPHOMAS, *B cell lymphoma, *DISEASE relapse, *T cells, *DUODENUM, *IMMUNOHISTOCHEMISTRY, *IMMUNOGLOBULIN genes, *EPSTEIN-Barr virus, *TUMORS |
مستخلص: |
We describe an unusual case of with de novo composite diffuse large B-cell lymphoma and enteropathy-type T-cell lymphoma involving the duodenum in a 65-year-old man with celiac disease. A segmental duodenum resection revealed that two neoplastic components had infiltrated the intestinal wall. The coexistence of two malignancies was confirmed by immunohistochemical and molecular biologic analysis, which revealed clonal T-cell receptor γ and immunoglobulin heavy chain gene rearrangements. Epstein-Barr virus was not detected in the B- and T-cell components. After chemotherapy, the patient experienced two relapses of enteropathy-type T-cell lymphoma only. We review the medical literature on composite B- and T-cell lymphomas and discuss their diagnosis, pathogenesis, prognosis and treatment. [ABSTRACT FROM AUTHOR] |
قاعدة البيانات: |
Academic Search Index |