التفاصيل البيبلوغرافية
| العنوان: |
Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19. |
| المؤلفون: |
Satici, Celal1 (AUTHOR) celalsatici@yahoo.com, Demirkol, Mustafa Asim1 (AUTHOR) dr_mad_26@hotmail.com, Sargin Altunok, Elif2 (AUTHOR) ifsargin@hotmail.com, Gursoy, Bengul1 (AUTHOR) bengulsimsek@gmail.com, Alkan, Mustafa2 (AUTHOR) mustafalkan58@gmail.com, Kamat, Sadettin1 (AUTHOR) kamatsadettin@gmail.com, Demirok, Berna2 (AUTHOR) bernagurbuz@hotmail.com, Surmeli, Cemile Dilsah1 (AUTHOR) drdilsah@hotmail.com, Calik, Mustafa3 (AUTHOR) drmustafacalik@yahoo.com, Cavus, Zuhal4 (AUTHOR) zuhalcavus74@gmail.com, Esatoglu, Sinem Nihal5 (AUTHOR) nihalesatoglu@gmail.com |
| المصدر: |
International Journal of Infectious Diseases. Sep2020, Vol. 98, p84-89. 6p. |
| مصطلحات موضوعية: |
*COVID-19, *RECEIVER operating characteristic curves, *ELECTRONIC health records, *COMMUNITY-acquired pneumonia, *LOGISTIC regression analysis |
| مصطلحات جغرافية: |
ISTANBUL (Turkey) |
| مستخلص: |
• The CURB-65 scores and pneumonia severity index (PSI) are widely used to predict mortality in patients with community-acquired pneumonia. • There is no scoring system to predict mortality in patients with COVID-19. • The PSI scores performed significantly better than the CURB-65 scores in predicting 30-day mortality, with a discriminatory ability of 91%. • Adding CRP levels to PSI scores did not improve their performance, as has also been observed in community-acquired pneumonia. The aim of the study was to analyze the usefulness of CURB-65 and the pneumonia severity index (PSI) in predicting 30-day mortality in patients with COVID-19, and to identify other factors associated with higher mortality. A retrospective study was performed in a pandemic hospital in Istanbul, Turkey, which included 681 laboratory-confirmed patients with COVID-19. Data on characteristics, vital signs, and laboratory parameters were recorded from electronic medical records. Receiver operating characteristic analysis was used to quantify the discriminatory abilities of the prognostic scales. Univariate and multivariate logistic regression analyses were performed to identify other predictors of mortality. Higher CRP levels were associated with an increased risk for mortality (OR: 1.015, 95% CI: 1.008–1.021; p < 0.001). The PSI performed significantly better than CURB-65 (AUC: 0.91, 95% CI: 0.88–0.93 vs AUC: 0.88, 95% CI: 0.85–0.90; p = 0.01), and the addition of CRP levels to PSI did not improve the performance of PSI in predicting mortality (AUC: 0.91, 95% CI: 0.88–0.93 vs AUC: 0.92, 95% CI: 0.89–0.94; p = 0.29). In a large group of hospitalized patients with COVID-19, we found that PSI performed better than CURB-65 in predicting mortality. Adding CRP levels to PSI did not improve the 30-day mortality prediction. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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