المؤلفون: Marinella Roberti, Elisa Giacomini, Alfonso Ciotta, Angela Nebbioso, Maurizio Recanatini, Federico Falchi, Rosaria Maria Pipitone, Antonietta Di Cristina, Stefania Grimaudo, Lucia Altucci, Cristina Ianni, Manlio Tolomeo

المساهمون: Giacomini, E, Nebbioso, Angela, Ciotta, A, Ianni, C, Falchi, F, Roberti, M, Tolomeo, M, Grimaudo, S, Cristina, Ad, Pipitone, Rm, Altucci, Lucia, Recanatini, M., Giacomini E, Nebbioso A, Ciotta A, Ianni C, Falchi F, Roberti M, Tolomeo M, Grimaudo S, Cristina AD, Pipitone RM, Altucci L, Recanatini M, Nebbioso, A, Cristina, AD, Pipitone, RM, Altucci, L, Recanatini, M

المصدر: ACS medicinal chemistry letters 5 (2014): 973–978. doi:10.1021/ml5000959
info:cnr-pdr/source/autori:Giacomini E.; Nebbioso A.; Ciotta A.; Ianni C.; Falchi F.; Roberti M.; Tolomeo M.; Grimaudo S.; Cristina A.D.; Pipitone R.M.; Altucci L.; Recanatini M./titolo:Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity/doi:10.1021%2Fml5000959/rivista:ACS medicinal chemistry letters/anno:2014/pagina_da:973/pagina_a:978/intervallo_pagine:973–978/volume:5

مصطلحات موضوعية: Multifunctional ligands, Cell cycle progression, HDAC inhibition, Inhibitory postsynaptic potential, Biochemistry, Settore BIO/13 - Biologia Applicata, HDAC, Drug Discovery, medicine, Cytotoxic T cell, antiproliferative activity, chimeric compound, stilbene, Cancer, biology, Chemistry, ANTIPROLIFERATIVE ACTIVITY, Organic Chemistry, multifunctional ligand, medicine.disease, Combinatorial chemistry, Settore CHIM/08 - Chimica Farmaceutica, Histone, STILBENES, biology.protein, HDAC INHIBITORS, Epigenetics, Histone deacetylase, Chimeric molecules

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8400fb57406fd3b5910977b29cad4c5bTest
http://hdl.handle.net/11591/197955Test

المؤلفون: Stefania Grimaudo, Rosaria Maria Pipitone, Nicola Gebbia, Maurizio Recanatini, Marinella Roberti, Antonietta Di Cristina, Andrea Cavalli, Daniela Pizzirani, Manlio Tolomeo

المساهمون: Pizzirani D., Roberti M., Cavalli A., Grimaudo S., Di Cristina A., Pipitone R.M., Gebbia N., Tolomeo M., Recanatini M., PIZZIRANI D, ROBERTI M, CAVALLI A, GRIMAUDO S, DI CRISTINA A, PIPITONE MR, GEBBIA N, TOLOMEO M, RECANATINI M

مصطلحات موضوعية: Stereochemistry, Cellular differentiation, Antineoplastic Agents, Apoptosis, HL-60 Cells, Biochemistry, S Phase, Small Molecule Libraries, chemistry.chemical_compound, Inhibitory Concentration 50, Biological profile, Cell Line, Tumor, Drug Discovery, Stilbenes, pharmacophores, Humans, General Pharmacology, Toxicology and Pharmaceutics, Phosphorylation, Pharmacology, Chemistry, Organic Chemistry, G1 Phase, Retinoblastoma, G1/S transition, Cell Differentiation, Cell cycle, Flow Cytometry, Combinatorial chemistry, antitumor agent, Antiproliferative Agents, Molecular Medicine, Triol, cell cycle, Pharmacophore, C-C coupling, K562 Cells

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8c1c377d6ce2160ee81b85c6a55305Test
http://hdl.handle.net/11585/60983Test

المؤلفون: Umberto Contaldo, Marinella Roberti, Francesco Musiani, Greta Bagnolini, Michele Cianci, Luca Mazzei, Stefano Ciurli

المساهمون: Mazzei L., Contaldo U., Musiani F., Cianci M., Bagnolini G., Roberti M., Ciurli S., Department of Pharmacy and Biotechnologies (FABIT), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology, University of Bologna, Viale Giuseppe Fanin, 40, 40127 Bologna, Italy, BioEnergie et Environnement (BEE), Laboratoire de Chimie et Biologie des Métaux (LCBM - UMR 5249), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Department of Agricultural, Food and Environmental Sciences, Università Politecnica delle Marche [Ancona] (UNIVPM)

المصدر: Angewandte Chemie / International edition 60(11), 6029-6035 (2020). doi:10.1002/anie.202014706
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, 60 (11), pp.6029-6035. ⟨10.1002/anie.202014706⟩
Angewandte Chemie International Edition, 2021, 60 (11), pp.6029-6035. ⟨10.1002/anie.202014706⟩

مصطلحات موضوعية: Models, Molecular, Reaction mechanism, Sporosarcina, Urease, Catechols, Crystallography, X-Ray, 010402 general chemistry, 01 natural sciences, Catalysis, Autocatalysis, chemistry.chemical_compound, nickel, Sulfanyl, Reactivity (chemistry), Sulfhydryl Compounds, Enzyme Inhibitors, enzyme inhibition, Density Functional Theory, chemistry.chemical_classification, [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, urease, Catechol, Molecular Structure, biology, 010405 organic chemistry, General Chemistry, [CHIM.CATA]Chemical Sciences/Catalysis, General Medicine, catechol, biology.organism_classification, Combinatorial chemistry, 3. Good health, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Kinetics, chemistry, Canavalia ensiformis, [SDV.TOX]Life Sciences [q-bio]/Toxicology, ddc:540, Thiol, biology.protein, quantum-mechanical calculations, atechols, quantum-mechanical calculation

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06291343a37b72ce31f138c4773ce99cTest
https://bib-pubdb1.desy.de/record/453695Test

المؤلفون: Marinella Roberti, Maurizio Recanatini, Daniela Pizzirani

المساهمون: Pizzirani D., Roberti M., Recanatini M.

المصدر: Tetrahedron Letters. 48:7120-7124

مصطلحات موضوعية: chemistry.chemical_classification, Spiro compound, Organic Chemistry, Chemical biology, Sequence (biology), Biochemistry, Combinatorial chemistry, Domino, chemistry, Suzuki reaction, Drug Discovery, Multi-component reaction, Diels alder, Knoevenagel condensation

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1fc8564e6789215354ab6f501bbb5aTest
https://doi.org/10.1016/j.tetlet.2007.07.214Test

المؤلفون: Marinella Roberti, Rosa Buonfiglio, Yuhong Wang, Gea-Ny Tseng, Matteo Masetti, Elisa Giacomini, Maurizio Recanatini

المساهمون: Giacomini, E., Buonfiglio, R., Masetti, M., Wang, Y., Tseng, G.-N., Roberti, M., Recanatini, M., DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE, Facolta' di FARMACIA, Da definire, AREA MIN. 03 - Scienze chimiche

المصدر: Scopus-Elsevier

مصطلحات موضوعية: ERG1 Potassium Channel, ligand-based virtual screening, hERG, Activators, electrophysiology, hERG potassium channel, ligand-based virtual screening, NS1643, parallel synthesis, hERG potassium channel, Computational biology, parallel synthesis, Ligands, Small Molecule Libraries, Structure-Activity Relationship, Drug Discovery, Potassium Channel Blockers, medicine, Humans, cardiovascular diseases, Activators, Virtual screening, Molecular Structure, biology, Chemistry, Organic Chemistry, NS1643, General Medicine, electrophysiology, Ligand (biochemistry), Small molecule, Combinatorial chemistry, Ether-A-Go-Go Potassium Channels, Potassium channel, High-Throughput Screening Assays, Computer Science Applications, Mechanism of action, biology.protein, medicine.symptom, Function (biology), Communication channel

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5caadeea54ad248f6a5d532111b973Test
http://hdl.handle.net/11585/517284Test

المؤلفون: Marinella Roberti, Giovanni Bottegoni, Laura Garuti

المساهمون: Garuti L, Roberti M, Bottegoni G, DIP. DI SCIENZE FARMACEUTICHE, DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE, Facolta' di FARMACIA, AREA MIN. 03 - Scienze chimiche, Da definire

المصدر: Current medicinal chemistry. 22(6)

مصطلحات موضوعية: Indoles, kinase, Pyridines, irreversible inhibitors, biological activity, Computational biology, SAR, Biology, ATP-competitive, heterocycles, inhibition, multi-target, antitumor, Biochemistry, Multikinase inhibitor, Drug Discovery, Screening method, Animals, Humans, Protein Kinase Inhibitors, Pharmacology, Kinase, irreversible inhibitor, Organic Chemistry, Biological activity, Combinatorial chemistry, Structural homology, Pyrimidines, Molecular Medicine, Pharmacophore, Protein Kinases, heterocycle, Cysteine

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d0c208695a04914b8e9de2bc3be52fTest
https://pubmed.ncbi.nlm.nih.gov/25511779Test

المؤلفون: Andrea Cavalli, Salvatore Bongarzone, Paolo Carloni, Marinella Roberti, Giuseppe Legname, Hoang Ngoc Ai Tran, Maria Laura Bolognesi

المساهمون: Bongarzone S, Tran HN, Cavalli A, Roberti M, Carloni P, Legname G, Bolognesi ML.

المصدر: Journal of medicinal chemistry 53 (2010): 8197–8201.
info:cnr-pdr/source/autori:Bongarzone, Salvatore; Hoang Ngoc Ai Tran; Cavalli, Andrea; Roberti, Marinella; Carloni, Paolo; Legname, Giuseppe; Bolognesi, Maria Laura/titolo:Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound/doi:/rivista:Journal of medicinal chemistry/anno:2010/pagina_da:8197/pagina_a:8201/intervallo_pagine:8197–8201/volume:53

مصطلحات موضوعية: PrPSc Proteins, Cell Survival, Chemistry, Stereochemistry, Rational design, Combinatorial chemistry, Bivalent (genetics), Cell Line, Mice, Oxidative Stress, Structure-Activity Relationship, Fibril formation, medicine.anatomical_structure, Prion infection, Drug Discovery, Benzoquinones, medicine, Acridines, Animals, Molecular Medicine, Structure–activity relationship, Amines, Cytotoxicity, Nucleus

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78a9bc536137a544517dabef6d3b2e5Test
http://hdl.handle.net/11585/93440Test