دورية أكاديمية
Improved perioperative outcomes and reduced inflammatory stress response in malignant robot-assisted colorectal resections:a retrospective cohort study of 298 patients
| العنوان: | Improved perioperative outcomes and reduced inflammatory stress response in malignant robot-assisted colorectal resections:a retrospective cohort study of 298 patients |
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| المؤلفون: | Cuk, Pedja, Simonsen, Randi Maria, Komljen, Mirjana, Nielsen, Michael Festersen, Helligsø, Per, Pedersen, Andreas Kristian, Mogensen, Christian Backer, Ellebæk, Mark Bremholm |
| المصدر: | Cuk , P , Simonsen , R M , Komljen , M , Nielsen , M F , Helligsø , P , Pedersen , A K , Mogensen , C B & Ellebæk , M B 2021 , ' Improved perioperative outcomes and reduced inflammatory stress response in malignant robot-assisted colorectal resections : a retrospective cohort study of 298 patients ' , World Journal of Surgical Oncology , vol. 19 , 155 . https://doi.org/10.1186/s12957-021-02263-wTest |
| سنة النشر: | 2021 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| مصطلحات موضوعية: | Colorectal cancer, Laparoscopic colorectal surgery, Minimally invasive surgery, Postoperative inflammatory stress response, Robot-assisted colorectal surgery, Surgical oncology, Prognosis, Prospective Studies, Humans, Treatment Outcome, Laparoscopy, Robotics, Colorectal Neoplasms/surgery, Retrospective Studies, Postoperative Complications, Robotic Surgical Procedures/adverse effects |
| الوصف: | Background: Robot-assisted surgery is increasingly implemented for the resection of colorectal cancer, although the scientific evidence for adopting this technique is still limited. This study’s main objective was to compare short-term complication rates, oncological outcomes, and the inflammatory stress response after colorectal resection for cancer performed laparoscopic or robot-assisted. Methods: We conducted a retrospective cohort study comparing the robot-assisted approach to laparoscopic surgery for elective malignant colorectal neoplasm. Certified colorectal and da Vinci ® robotic surgeons performed resections at a Danish tertiary colorectal high volume center from May 2017 to March 2019. We analyzed the two surgical groups using uni- and multivariate regression analyses to detect differences in intra- and postoperative clinical outcomes and the inflammatory stress response. Results: Two hundred and ninety-eight patients were enrolled in the study. Significant differences favoring robot-assisted surgery was demonstrated for; length of hospital stay (4 days, interquartile range (4, 5) versus 5 days, interquartile range (4–7), p < 0.001), and intraoperative blood loss (50 mL, interquartile range (20–100) versus 100 mL, interquartile range (50–150), p < 0.001) compared to laparoscopic surgery. The inflammatory stress response was significantly higher after laparoscopic compared to robot-assisted surgery reflected by an increase in C-reactive protein concentration (exponentiated coefficient = 1.23, 95% confidence interval (1.06–1.46), p = 0.008). No differences between the two groups were found concerning mortality, microradical resection rate, conversion to open surgery, and surgical or medical short-term complication rates. Conclusion: Robot-assisted surgery is feasible and can be safely implemented for colorectal resections. The robot-assisted approach, when compared to laparoscopic surgery, was associated with improved intra- and postoperative outcomes. Extensive prospective studies are needed to ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://portal.findresearcher.sdu.dk/da/publications/f967bc03-872e-41ab-bd4b-3697f083ee62Test |
| DOI: | 10.1186/s12957-021-02263-w |
| الإتاحة: | https://doi.org/10.1186/s12957-021-02263-wTest https://portal.findresearcher.sdu.dk/da/publications/f967bc03-872e-41ab-bd4b-3697f083ee62Test https://findresearcher.sdu.dk/ws/files/183278838/Cuk2021_Article_ImprovedPerioperativeOutcomesA.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.C7EBECD5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s12957-021-02263-w |
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