التفاصيل البيبلوغرافية
| العنوان: |
Macronutrient-specific effect of the MTNR1B genotype on lipid levels in response to 2 year weight-loss diets |
| المؤلفون: |
Goñi-Mateos, L. (Leticia), Sun, D. (Dianjianyi), Heianza, Y. (Yoriko), Wang, T. (Tiange), Huang, T. (Tao), Cuervo, M. (Marta), Martinez, J.A. (José Alfredo), Shang, X. (Xiaoyun), Bray, G.A. (George A.), Sacks, F.M. (Frank M.), Qi, L. (Lu) |
| بيانات النشر: |
American Society for Biochemistry and Molecular Biology |
| سنة النشر: |
2018 |
| المجموعة: |
dadun - Depósito Académico Digital Universidad de Navarra |
| مصطلحات موضوعية: |
Cholesterol, Clinical trials, Diet and dietary lipids, Gene-diet interaction, Genetics, High-fat diet, Lipid metabolism, Low density lipoprotein, Melatonin receptor 1B, Weight-loss intervention |
| الوصف: |
Compelling evidence indicates that lipid metabolism is in partial control of the circadian system. In this context, it has been reported that the melatonin receptor 1B (MTNR1B) genetic variant influences the dynamics of melatonin secretion, which is involved in the circadian system as a chronobiotic. The objective was to analyze whether the MTNR1B rs10830963 genetic variant was related to changes in lipid levels in response to dietary interventions with different macronutrient distribution in 722 overweight/obese subjects from the POUNDS Lost trial. We did not find a significant association between the MTNR1B genotype and changes in lipid metabolism. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
https://hdl.handle.net/10171/65620Test |
| الإتاحة: |
https://hdl.handle.net/10171/65620Test |
| حقوق: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.5427C6ED |
| قاعدة البيانات: |
BASE |
