التفاصيل البيبلوغرافية
| العنوان: |
Therapeutic education as a tool to improve patient‐reported and clinical outcomes after renal transplantation: results of the EPHEGREN multicenter retrospective cohort study. |
| المؤلفون: |
Villeneuve, Claire, Rerolle, Jean‐phillipe, Couzi, Lionel, Westeel, Pierre‐Francois, Etienne, Isabelle, Esposito, Laure, Kamar, Nassim, Büchler, Mathias, Thierry, Antoine, Marquet, Pierre, Monchaud, Caroline |
| المصدر: |
Transplant International; Nov2021, Vol. 34 Issue 11, p2341-2352, 12p |
| مصطلحات موضوعية: |
TRANSPLANTATION of organs, tissues, etc., TREATMENT effectiveness, KIDNEY transplantation, COHORT analysis, CLINICAL trials, SURVIVAL rate, ONE-way analysis of variance |
| مستخلص: |
Summary: Patients are not always aware of the inconveniences associated with renal transplantation, which they compare with a « rebirth », and from which they expect complete recovery. Therapeutic education is proposed to prepare patients for their life after transplantation. This study evaluated the impact of pretransplant therapeutic education on patient‐reported outcomes and rejection‐free survival over the first year. We collected data from 383 renal transplant patients followed‐up in seven centers. Patients who benefited from therapeutic education before transplantation (N = 182) were compared with patients who did not (N = 139) for quality‐of‐life, adherence and adverse events using the Pearson's chi‐square test, one‐way ANOVA or t‐test. The association between therapeutic education and time to acute rejection was investigated using Cox models. The patients who benefited from therapeutic education reported adverse events less frequently (e.g., tremor: 9% vs. 32.4%, P = 0.01) and better quality‐of‐life (MCS‐QOL: 50.7 ± 8.1 vs. 47.7 ± 9.5, P = 0.02; PCS‐QOL: 49.1 ± 7.1 vs. 46.0 ± 9.2, P = 0.013). No difference was found on adherence. Rejection‐free survival was slightly better in the therapeutic education group (HR = 0.44, 95% CI = [0.19–1.01]). This multicenter retrospective cohort study suggests that integrating therapeutic education to care pathways entails clinical benefit, in terms of quality‐of‐life, self‐reported adverse events and rejection‐free survival. Randomized clinical trials are necessary to confirm this. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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