التفاصيل البيبلوغرافية
| العنوان: |
Prevalence of hepatopancreatic injury and clinical outcomes in patients with COVID-19 in USA. |
| المؤلفون: |
Rastogi, Vaibhav, Banwait, Ranjit, Singh, Devina, Toklu, Hale, Finer, Lexie, Parajuli, Dipendra, Ganti, Latha |
| المصدر: |
International Journal of Emergency Medicine; 11/6/2021, Vol. 14 Issue 1, p1-7, 7p, 5 Charts |
| مصطلحات موضوعية: |
LIVER injuries, PANCREATIC injuries, LENGTH of stay in hospitals, ALKALINE phosphatase, PROTHROMBIN time, LIPASES, CONFIDENCE intervals, AGE distribution, RACE, CIRRHOSIS of the liver, LIVER diseases, PANCREATIC diseases, SEVERITY of illness index, SERUM albumin, SEX distribution, LACTATE dehydrogenase, DESCRIPTIVE statistics, AMINOTRANSFERASES, ODDS ratio, BILIRUBIN |
| مصطلحات جغرافية: |
UNITED States |
| مستخلص: |
Background: (1) To determine the prevalence of hepatopancreatic injury in coronavirus disease 2019 (COVID-19) patients. (2) To correlate hepatopancreatic injury in COVID-19 with mortality, disease severity, and length of stay in this cohort. Results: Forty-five thousand three hundred sixty patients were included in the analysis, 62.82% of which had either hepatic or pancreatic injury. There was a significant upward trend in transaminases, alkaline phosphatase, prothrombin time, bilirubin, lactate dehydrogenase, and lipase and a downward trend in albumin with an increase in disease severity. COVID-19-positive patients with hepato-pancreatic injury have a significantly higher mortality (OR 3.39, 95%CI 3.15–3.65) after controlling for the differences in age, sex, race/ethnicity, liver cirrhosis, and medication exposures. They also have increased disease severity (OR 2.7, 95%CI 2.5–2.9 critical vs mild/moderate; OR 1.4, 95% CI 1.3–1.5 severe vs mild/moderate) and longer hospital length of stay (2 days). Conclusion: COVID-19 can cause liver injury. Mortality, disease severity, and hospital length of stay are increased in COVID-19 patients with hepatopancreatic injury. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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