المؤلفون: Ulrich Jaeger, Marek Borsky, Jan Oppelt, Laura Z. Rassenti, Medhat Shehata, Václav Šeda, Thomas J. Kipps, Gabriela Pavlasova, Jennifer R. Brown, Daniel Filip, Kvetoslava Liskova, Šárka Pospíšilová, Eva Vojackova, Lenka Kostalova, Matthew S. Davids, Marek Mráz, Katerina Cerna, Sonali Sharma, Jiri Mayer, Andrea Janíková, Pedro Faria Zeni, Stacey M. Fernandes, Veronika Šandová, Laura Ondrisova, Michael Doubek, Leos Kren

المصدر: Blood

مصطلحات موضوعية: Adult, Male, T cell, Chronic lymphocytic leukemia, Immunology, B-cell receptor, Biology, Biochemistry, Article, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, 0302 clinical medicine, Piperidines, immune system diseases, hemic and lymphatic diseases, microRNA, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Humans, CD40 Antigens, Aged, 030304 developmental biology, 0303 health sciences, TNF Receptor-Associated Factor 4, Adenine, breakpoint cluster region, Cell Biology, Hematology, Middle Aged, Prognosis, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Gene Expression Regulation, Neoplastic, Survival Rate, MicroRNAs, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Proto-Oncogene Proteins c-bcr, Cancer research, Female, Signal transduction, CD5, Idelalisib, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a337b68bb9ac88d669bfb33ed5069dTest
https://doi.org/10.1182/blood.2020005627Test

المؤلفون: Peter Valent, Philipp B. Staber, Medhat Shehata, Dita Demirtas, Farghaly Ali, Martin Hilgarth, Rainer Hubmann, Ulrich Jäger, André F. Rendeiro, Mohammad Araghi, Susanne Schnabl, Christian Schmidl, Christoph C. Zielinski

المصدر: Cells
Volume 9
Issue 6
Cells, Vol 9, Iss 1484, p 1484 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, RO4929097, Chronic lymphocytic leukemia, FCER2 (CD23), Cell, binary cell fate decision, NR4A1, Apoptosis, chemistry.chemical_compound, 0302 clinical medicine, NOTCH2, NOTCH3, hemic and lymphatic diseases, Nuclear Receptor Subfamily 4, Group A, Member 1, Tumor Cells, Cultured, Receptor, Notch2, Regulatory Elements, Transcriptional, CD5+ B-cell homeostasis, lcsh:QH301-705.5, Receptor, Notch3, Aged, 80 and over, Gliotoxin, Chemistry, General Medicine, ATAC-seq, Middle Aged, Chromatin, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Signal Transduction, Adult, endocrine system, gliotoxin, Cell Survival, Notch signaling pathway, Down-Regulation, Antineoplastic Agents, Article, 03 medical and health sciences, γ-secretase inhibitors, Downregulation and upregulation, chronic lymphocytic leukemia (CLL), medicine, Humans, Lectins, C-Type, Viability assay, RNA, Messenger, Aged, Dose-Response Relationship, Drug, Receptors, IgE, positive/negative selection, Benzazepines, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, 030104 developmental biology, lcsh:Biology (General), Cancer research, Amyloid Precursor Protein Secretases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9bd0dcbb71596a8d6e2867de4d8fb4Test
http://europepmc.org/articles/PMC7348714Test

المؤلفون: Harald Herrmann, Thomas W. Grunt, Peter Valent, Karoline V. Gleixner, Christoph C. Zielinski, Gregor Eisenwort, Heidrun Karlic, Ulrich Jäger, Thomas Rülicke, Michael Willmann, Emir Hadzijusufovic, Medhat Shehata, Rainer Hubmann, Gregor Hoermann, Wolfgang R. Sperr, Brigitte Marian, Hubert Pehamberger, Michael Pfeilstöcker, Edgar Selzer, Felix Keil, Axel Schulenburg, Barbara Peter

المصدر: Wiener Klinische Wochenschrift

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Chronic lymphocytic leukemia, medicine.medical_treatment, Context (language use), Review Article, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Cancer stem cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Internal medicine, medicine, Humans, Leukemic stem cells, Hematology, Cancer stem cells, business.industry, Myelodysplastic syndromes, Precision medicine, Myeloid leukemia, General Medicine, medicine.disease, Leukemia, 030104 developmental biology, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Immunotherapy, sense organs, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99c38121639b8ee6fe43bc290e95476Test
https://doi.org/10.1007/s00508-018-1355-7Test

المؤلفون: Ulrich Jaeger, Marek Mráz, Václav Šeda, Matthew S. Davids, Daniel Filip, Marek Borsky, Jiri Mayer, Laura Ondrisova, Laura Z. Rassenti, Michael Doubek, Pedro Faria Zeni, Lenka Kostalova, Šárka Pospíšilová, Medhat Shehata, Eva Vojackova, Gabriela Pavlasova, Thomas J. Kipps, Veronika Šandová, Jennifer R. Brown, Sonali Sharma

المصدر: Cancer Research. 81:2368-2368

مصطلحات موضوعية: Cancer Research, CD40, biology, Chronic lymphocytic leukemia, Follicular lymphoma, breakpoint cluster region, medicine.disease, medicine.anatomical_structure, Oncology, microRNA, medicine, biology.protein, Cancer research, Bone marrow, Lymph, Lymph node

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1f036a62de1e6e4c766abc63b224cc1eTest
https://doi.org/10.1158/1538-7445.am2021-2368Test

المؤلفون: Michaela Gruber, Martin Hilgarth, Stefan Kubicek, Edit Porpaczy, Christian Schmidl, Rainer Hubmann, Nikolaus Krall, Anna Ringler, Philipp B. Staber, Christina Taubert, Mohammad Araghi, Dita Demirtas, Gregory I. Vladimer, Oscar Lopez de la Fuente, Medhat Shehata, Giulio Superti-Furga, Berend Snijder, Gregor Hoermann, Tea Pemovska, Cathrin Skrabs, Thomas Krausgruber, Kathrin Runggatscher, Ulrich Jäger, Susanne Schnabl, André F. Rendeiro, Christoph Bock

المصدر: Nature Chemical Biology, 15 (3)
Nature Chemical Biology

مصطلحات موضوعية: Epigenomics, Drug, Chronic lymphocytic leukemia, media_common.quotation_subject, Cell Cycle Proteins, Protein Serine-Threonine Kinases, PLK1, Article, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Piperidines, Proto-Oncogene Proteins, Agammaglobulinaemia Tyrosine Kinase, medicine, Humans, Bruton's tyrosine kinase, Epigenetics, Protein Kinase Inhibitors, Molecular Biology, 030304 developmental biology, media_common, 0303 health sciences, biology, business.industry, Adenine, TOR Serine-Threonine Kinases, 030302 biochemistry & molecular biology, Cell Biology, Epigenome, Protein-Tyrosine Kinases, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Chromatin, 3. Good health, Drug Combinations, Leukemia, Pyrimidines, chemistry, Drug Resistance, Neoplasm, Ibrutinib, Cancer research, biology.protein, Pyrazoles, Single-Cell Analysis, business, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8ec57ac57f9b814e4af6f250e81781Test
https://hdl.handle.net/20.500.11850/328366Test

المؤلفون: Michaela Gruber, Trang Le, Ulrich Jaeger, Karin Fleiss, Katrina Vanura, Judith Bellemare, Martin Bilban, Andreas Gleiss, Christine Mannhalter, Sonja Zehetmayer, Alexander Gaiger, Edit Porpaczy, Gregor Hoermann, Chantal Guillemette, Cathrin Skrabs, Éric Lévesque, Medhat Shehata

المصدر: Blood. 121:1175-1183

مصطلحات موضوعية: Male, Glucuronosyltransferase, Chronic lymphocytic leukemia, Immunology, Gene Dosage, Antineoplastic Agents, Kaplan-Meier Estimate, Pharmacology, Biochemistry, Gene dosage, Disease-Free Survival, Minor Histocompatibility Antigens, chemistry.chemical_compound, Risk Factors, Cell Line, Tumor, Biomarkers, Tumor, medicine, Humans, RNA, Messenger, RNA, Neoplasm, RNA, Small Interfering, Vorinostat, Aged, Gene knockdown, Base Sequence, biology, Cell Biology, Hematology, Middle Aged, Prognosis, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Uridine, Up-Regulation, Fludarabine, Gene expression profiling, chemistry, Case-Control Studies, Gene Knockdown Techniques, biology.protein, Cancer research, Female, Transcriptome, Vidarabine, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2769223ba0fdfd839a56ee334bf12f0Test
https://doi.org/10.1182/blood-2012-08-447359Test

المؤلفون: Ulrich Jäger, Katrina Vanura, Susanne Schnabl, Georg Hopfinger, E. Porpaczy, Martin Bilban, Stephan Stilgenbauer, Michael Hallek, Rainer Hubmann, Karin Eigenberger, Dita Demirtas, Martin Hilgarth, Josef D. Schwarzmeier, Medhat Shehata, Ilse Schwarzinger, Alexander Gaiger, Christa Fonatsch, Alexander W. Hauswirth, Daniel Heintel

المصدر: Leukemia. 24:2122-2127

مصطلحات موضوعية: Male, Cancer Research, business.industry, Gene Expression Profiling, Integrin alpha4, Chronic lymphocytic leukemia, Hematology, Middle Aged, Antigens, CD20, medicine.disease, Bioinformatics, Leukemia, Lymphocytic, Chronic, B-Cell, Gene expression profiling, Phosphatidylinositol 3-Kinases, Hyaluronan Receptors, Oncology, Cancer research, Humans, Medicine, Female, Identification (biology), business, Biomarkers, Aged, Oligonucleotide Array Sequence Analysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b291531d8dd22ce42a98c14981aaa9Test
https://doi.org/10.1038/leu.2010.220Test

المؤلفون: Christoph C. Zielinski, Josef D. Schwarzmeier, Andrea Hoelbl, Ulrich Jaeger, Elena Ponath, Susanne Schnabl, Medhat Shehata, Alexander Gaiger, Sigrun Badrnya, Claudia Lehner, Rainer Hubmann, Markus Duechler, Dita Demirtas, Martin Hilgarth

المصدر: Blood. 116:2513-2521

مصطلحات موضوعية: Stromal cell, Chronic lymphocytic leukemia, Immunology, Apoptosis, Bone Marrow Cells, Biochemistry, medicine, Humans, PTEN, Tensin, Casein Kinase II, Protein kinase B, Cells, Cultured, PI3K/AKT/mTOR pathway, Tumor microenvironment, biology, PTEN Phosphohydrolase, Cell Biology, Hematology, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, biology.protein, Cancer research, Phosphatidylinositol 3-Kinase, Stromal Cells, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8f79118ce7cbe2adaf06597679060aTest
https://doi.org/10.1182/blood-2009-10-248054Test

المؤلفون: Ulrich Jaeger, Susanne Schnabl, Thomas Krausgruber, Philipp B. Staber, Gregory I. Vladimer, Christian Schmidl, Edit Porpaczy, Medhat Shehata, Dita Demirtas, Berend Snijder, Michaela Gruber, Tea Pemovska, Stefan Kubicek, Andre Renderio, Giulio Superti-Furga, Oscar Lopez de la Fuente, Rainer Hubmann, Gregor Hoermann, Martin Hilgrath, Christoph Bock, Anna Ringler, Cathrin Skrabs, Mohammad Araghi, Nikolaus Krall

المصدر: Blood. 130:800-800

مصطلحات موضوعية: Oncology, medicine.medical_specialty, biology, business.industry, Bortezomib, Venetoclax, Chronic lymphocytic leukemia, Immunology, Volasertib, Cell Biology, Hematology, medicine.disease, Biochemistry, Carfilzomib, chemistry.chemical_compound, chemistry, Ibrutinib, Internal medicine, Proteasome inhibitor, medicine, biology.protein, Bruton's tyrosine kinase, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::64c610d77ba1721632dfc75928c42c8aTest
https://doi.org/10.1182/blood.v130.suppl_1.800.800Test

المؤلفون: Medhat Shehata, Zeev Estrov, William Plunkett, Rong Chen, Susanne Schnabl, Antonina V. Kurtova, Maite P. Quiroga, Kumudha Balakrishnan, William G. Wierda, Mariela Sivina, Neil E. Kay, Varsha Gandhi, Wei Ding, Michael J. Keating, Jan A. Burger, Ulrich Jäger

المصدر: Blood. 114:4441-4450

مصطلحات موضوعية: Programmed cell death, Stromal cell, Chronic lymphocytic leukemia, Blotting, Western, Immunology, Antineoplastic Agents, Apoptosis, Bone Marrow Cells, Cell Communication, Biology, Biochemistry, Mice, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, Cell Adhesion, medicine, Animals, Humans, Cell adhesion, neoplasms, Cells, Cultured, Lymphoid Neoplasia, Mesenchymal stem cell, Cell Biology, Hematology, Flow Cytometry, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Coculture Techniques, Leukemia, medicine.anatomical_structure, Drug Resistance, Neoplasm, Cell culture, Cancer research, Bone marrow, Stromal Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf806017d8c813fa343a6f464ca6682eTest
https://doi.org/10.1182/blood-2009-07-233718Test