التفاصيل البيبلوغرافية
| العنوان: |
Portal vein thrombosis in a patient with severe hemophilia B: A challenging balanced management. |
| المؤلفون: |
Benitez‐Hidalgo, Olga, Suito Alcántara, Milagros, Martinez Garcia, Maria Fernanda, Campoy, Desiree, Olivera, Pavel, Gironella Mesa, Mercedes, Juarez‐Gimenez, Juan Carlos |
| المصدر: |
Clinical Case Reports; Feb2024, Vol. 12 Issue 2, p1-4, 4p |
| مصطلحات موضوعية: |
HEMOPHILIACS, PORTAL vein, LOW-molecular-weight heparin, BLOOD coagulation factor IX, CENTRAL venous catheters |
| مستخلص: |
Key Clinical Message: The increased life expectancy in patients with hemophilia (PwH) over the last years has raised the incidence of comorbidities, including thromboembolic events. Thromboembolic events are rare in PwH and most of them occur in the presence of exogenous risk factors. There is still scarce scientific evidence on the optimal antithrombotic treatment and management approach in this population. In the hemophilic population thromboembolic events are rare. Most of them are often multifactorial and occur in the presence of both exogenous (orthopedic surgery, intensive replacement therapy, use of central venous catheters...) and endogenous (cardiovascular diseases) risk factors. We describe the case of a 43‐year‐old patient with severe hemophilia B (sHB) receiving prophylaxis with eftrenonacog alfa (rFIXFc) and antithrombotic treatment due to portal vein thrombosis. The patient was treated with extended half‐ life factor IX (EHL‐FIX) prophylaxis maintaining higher trough levels to avoid new bleeding episodes associated to the underlying disease and the use of antithrombotic therapy with low molecular weight heparin. EHL‐FIX concentrates allow prolonged intervals between intravenous infusions and higher hemostatic protection thanks to increased factor trough levels. This current case report provides clinical evidence in antithrombotic management in a patient with severe hemophilia B. [ABSTRACT FROM AUTHOR] |
|
Copyright of Clinical Case Reports is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder