المؤلفون: Sunkara, Sesh Kamal¹ sesh.sunkara1@nhs.net, LaMarca, Antonio², Polyzos, Nikolaos P.³, Seed, Paul T.⁴, Khalaf, Yakoub⁵

المصدر: Human Reproduction. Oct2016, Vol. 31 Issue 10, p2261-2267. 7p. 1 Diagram, 2 Charts, 2 Graphs.

مصطلحات موضوعية: *CHILDBIRTH, *PREMATURE labor, *PREGNANCY complications, *FERTILIZATION in vitro, *HEALTH outcome assessment, *LOW birth weight, *BIRTH rate, *GESTATIONAL age, *PREMATURE infants, *EVALUATION of medical care, *INDUCED ovulation, *PREGNANCY, PERINATAL care

مستخلص: Study Question: Does ovarian stimulation affect perinatal outcomes of preterm birth (PTB) and low birth weight (LBW) following IVF treatment.Summary Answer: Despite no significant differences in the risks of PTB and LBW between stimulated and unstimulated IVF in the present study, the study cannot exclude the effect of ovarian stimulation on the perinatal outcomes following IVF.What Is Already Known: Pregnancies resulting from assisted reproductive treatments (ART) are associated with a higher risk of pregnancy complications compared to spontaneously conceived pregnancies attributed to the underlying infertility and the in vitro fertilization techniques. It is of interest to determine the effect size of ovarian stimulation use in achieving a live birth and whether ovarian stimulation that is routinely used in IVF, affects perinatal outcomes of birth weight and gestational age at delivery compared to unstimulated IVF.Study Design, Size, Duration: Anonymous data were obtained from the Human Fertilisation and Embryology Authority (HFEA), the statutory regulator of ART in the UK. The HFEA has collected data prospectively on all ART performed in the UK since 1991. Data from 1991 to 2011 comprising a total of 591 003 fresh IVF ± ICSI cycles involving 584 835 stimulated IVF cycles and 6168 unstimulated IVF cycles were analyzed.Participants/materials, Setting, Methods: Data on all women undergoing either stimulated or unstimulated fresh IVF ± ICSI cycles during the period from 1991 to 2011 were analyzed to compare live birth rates, singleton live birth rates, perinatal outcomes of PTB, early PTB (<32 weeks), LBW and very LBW (<1500 grams) among singleton live births. Adjusted logistic regression was performed for each perinatal outcome for confounding factors: female age, period of treatment, cause of infertility, number of previous IVF cycles and previous live birth.Main Results and the Role Of Chance: Analysis of the large nationwide data demonstrated 3.5 times (95% confidence interval (CI): 3.1-3.9) as many unstimulated IVF cycles being required to achieve one live birth compared to stimulated IVF and 2.9 times (95% CI: 2.6-3.2) as many unstimulated IVF cycles being required to achieve one singleton live birth compared to stimulated IVF. There was no significant difference in the unadjusted odds for PTB (odds ratio (OR) 1.27, 95% CI: 0.80-2.00) and LBW (OR 1.48, 95% CI: 0.90-2.42) between stimulated and unstimulated IVF cycles. There was no significant difference in the risk of the adverse perinatal outcomes after adjusting for potential confounders; PTB (adjusted odds ratio (aOR) 1.43, 95% CI: 0.91-2.26) and LBW (aOR 1.58, 95% CI: 0.96-2.58).Limitations, Reasons For Caution: Although the analysis was adjusted for a number of important confounders, the dataset had no information on smoking, body mass index (BMI) and the medical history of women during pregnancy to allow adjustment. Anonymized nature of the dataset did not make it permissible to analyse one cycle per woman. Given the smaller number of perinatal events with unstimulated IVF, a larger study is needed to investigate further.Wider Implications Of the Findings: Analysis of this large dataset demonstrates that ovarian stimulation has a vital role in maximizing efficacy of IVF. Although there were no significant differences for PTB and LBW following stimulated compared to unstimulated IVF, the CIs were wide enough to include possible clinically important effects.Study Funding/competing Interests: No funding was obtained. There are no competing interests to declare. [ABSTRACT FROM AUTHOR]

المؤلفون: Di Tommaso, Mariarosaria¹ (AUTHOR) mariarosaria.ditommaso@unifi.it, Seravalli, Viola¹ (AUTHOR), Arduino, Silvana² (AUTHOR), Bossotti, Carlotta² (AUTHOR), Sisti, Giovanni¹ (AUTHOR), Todros, Tullia² (AUTHOR)

المصدر: Journal of Obstetrics & Gynaecology. Aug2016, Vol. 36 Issue 6, p715-718. 4p.

مصطلحات موضوعية: *PREMATURE labor prevention, *CERVIX uteri, *TWINS, *CHILDBIRTH, *DELIVERY (Obstetrics)

مستخلص: A retrospective study was conducted to evaluate the effect of Arabin cervical pessary in twin pregnancies with cervical length (CL)  <25 mm between 21 and 31 weeks. Forty patients receiving pessary were matched with 40 controls without pessary. They were matched for gestational age (GA) at admission and CL. GA at delivery, delivery before 36, 34 and 32 weeks, latency between detection of short cervix and delivery, and duration of hospital admission were compared between groups. Women with the pessary delivered at higher GA compared to controls (35 vs. 33 weeks, p = 0.02). Cervical pessary significantly reduced the incidence of delivery  <36 and  < 34 weeks (p < 0.05), but not before 32 weeks. Interval between detection of short cervix and delivery was longer in the pessary group and duration of hospital admission was shorter (p = 0.03) compared to women without pessary. [ABSTRACT FROM AUTHOR]

المؤلفون: Zgutka, Kinga, Prasanth, Kaninghat, Pinero-Bernardo, Shirley, Lew, Lily Q., Cervellione, Kelly, Rhythm, Rhythm, Rahman, Lubna, Dolmaian, Gigliola, Cohen, Lourdes

المصدر: Journal of Perinatal Medicine; Jul2021, Vol. 49 Issue 6, p691-696, 6p

مصطلحات موضوعية: HOSPITALS, CHILDBIRTH, LENGTH of stay in hospitals, COVID-19, NEONATAL intensive care, PREGNANT women, CASE-control method, NEONATAL intensive care units, PREGNANCY outcomes, BIRTH weight, VERTICAL transmission (Communicable diseases), PREMATURE labor, PREGNANCY

مصطلحات جغرافية: NEW York (State)

مستخلص: To compare clinical characteristics and outcomes of infants born to COVID-19 to non COVID-19 mothers at delivery in a community hospital in Queens, New York. Case-control study conducted March 15 to June 15, 2020. Cases were infants born to mothers with laboratory-confirmed COVID-19 infection at delivery. The infant of non COVID-19 mother born before and after each case were selected as controls. Of 695 deliveries, 62 (8.9%) infants were born to COVID-19 mothers; 124 controls were selected. Among cases, 18.3% were preterm compared to 8.1% in controls (p=0.04). In preterm cases, birth weight was not significantly different between groups. However, there was a significantly higher proportion of neonatal intensive care unit (NICU) admissions, need for respiratory support, suspected sepsis, hyperbilirubinemia, feeding intolerance and longer length of stay (LOS) in preterm cases. Among term cases, birth weight and adverse outcomes were not significantly different between cases and controls except for more feeding intolerance in cases. All infants born to COVID-19 mothers were COVID-19 negative at 24 and 48 h of life. No infants expired during birth hospitalization. Significantly, more infants of COVID-19 mothers were premature compared to controls. Preterm cases were more likely to have adverse outcomes despite having similar birth weight and gestational age. These differences were not seen among full term infants. Health care providers should anticipate the need for NICU care when a COVID-19 mother presents in labor. [ABSTRACT FROM AUTHOR]

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المؤلفون: Dosar, Raghad Z., Meran, Najmah M.

المصدر: Indian Journal of Forensic Medicine & Toxicology; Jul-Sep2021, Vol. 15 Issue 3, p943-947, 5p

مصطلحات موضوعية: PREGNANT women, PREGNANCY outcomes, BIRTH weight, WOMEN'S hospitals, THIRD trimester of pregnancy, PREMATURE labor, CHILDBIRTH, NUTRITION counseling

مصطلحات جغرافية: BAGHDAD (Iraq)

مستخلص: Objective: To assess the impact of pregnant women’s depression state upon their pregnancy outcome Methodology: A descriptive purposive study was used to assess the impact of pregnant women’s depression state on their pregnancy outcomes. The study was conducted from (22^nd \ September \ 2020 to 15^th \ February \ 2021). A non-probability sample (purposive sample) was selected from 100 women. Data were collected through an interview with the mother in the counseling clinic, during the third trimester of pregnancy, as well as after childbirth in the labour wards to assess the outcome of pregnancy. Data were analyzed through descriptive statistics (frequency and percentages). Results: The most important thing observed in this study was the negative pregnancy outcome for women suffering from depression during pregnancy. Low birth weight (31%), premature labor (22%), stillbirth (2%), intrauterine growth restriction (1%) Recommendations: The study recommends according to the results. We suggest that health care providers pay attention to the mental state of pregnant women. Providing training and scheduling support during pregnancy for mothers in order to identify risk factors and achieve skills and knowledge to support mothers, as well as providing a soothing atmosphere to ensure a peaceful environment for pregnant women. [ABSTRACT FROM AUTHOR]

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المصدر: Pediatrics Week; 3/15/2024, p755-755, 1p

مصطلحات موضوعية: PHEOCHROMOCYTOMA, UNIVERSITY hospitals, CHILDBIRTH, MEDICAL care, PARAGANGLIOMA, PREMATURE labor

مستخلص: A recent study conducted in Sweden examined the impact of maternal pheochromocytoma (PPGL) on both the mother and child during childbirth. The study found that while preterm delivery was more common in mothers with PPGL, there were no cases of maternal or fetal mortality. Additionally, there were no observed long-term impacts on the children. The study suggests the need for increased awareness of this diagnosis and highlights the importance of timely tumor removal. [Extracted from the article]

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المصدر: Women's Health Weekly; 2024, p1179-1179, 1p

مصطلحات موضوعية: PREMATURE infants, PREMATURE labor, RESEARCH personnel, CHILDBIRTH, BLOOD proteins, FETAL physiology, CARRIER proteins

الشركة/الكيان: TECHNISCHE Universiteit Eindhoven

مستخلص: A recent report from researchers at Eindhoven University of Technology discusses the development of an extrauterine environment for extremely premature infants, known as Artificial Placenta and Artificial Womb (APAW) technology. This technology aims to provide an optimal environment for newborn development by allowing further lung maturation and delaying gas exposure to oxygen. The report analyzes relevant fetal physiology literature, provides insights from APAW studies, and identifies considerations for the obstetric procedure of transferring an infant from the native uterus to an APAW system. The researchers also provide suggestions to improve sterility, fetal and maternal well-being, and the prevention of neonatal transition. [Extracted from the article]

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المصدر: Women's Health Weekly; 2024, p965-965, 1p

مصطلحات موضوعية: LOW birth weight, PRENATAL care, RESEARCH personnel, CHILDBIRTH, LIFE sciences, PREMATURE labor

مستخلص: A recent study conducted by researchers from the University of Indonesia examined the association between antenatal care (ANC) utilization and low birth weight (LBW) children among women with high-risk births. The study utilized data from the 2017 Indonesia Demographic and Health Survey and found that adequate ANC utilization was significantly associated with LBW among women with more than two children. Preterm birth was also found to be more likely to result in LBW. The researchers concluded that there is a need for increased monitoring of pregnant women with high-risk births and for improved implementation of qualified ANC standards. [Extracted from the article]

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المصدر: Pediatrics Week; 2/2/2024, p51-51, 1p

مصطلحات موضوعية: HEPATITIS B vaccines, PREMATURE labor, CHILDBIRTH, LOW birth weight, HEPATITIS

مصطلحات جغرافية: ANHUI Sheng (China)

مستخلص: A study conducted by Anhui Medical University in China found that preterm birth (PTB) children have lower immune persistence after receiving the hepatitis B vaccine compared to full-term children. The study included 1027 participants, with 505 PTB children and 522 full-term children. The PTB group had a significantly lower negative rate of hepatitis B surface antibody (HBsAb) and a lower geometric mean concentration (GMC) of HBsAb compared to the control group. The study suggests that very preterm infants and preterm low birth weight infants may require priority for booster vaccination. [Extracted from the article]

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المؤلفون: Klerman, Lorraine V.¹, Cliver, Suzanne P.², Goldenberg, Robert L.²

المصدر: American Journal of Public Health. Aug1998, Vol. 88 Issue 8, p1182-1185. 4p. 4 Charts.

مصطلحات موضوعية: PREGNANCY, PREMATURE labor, PRENATAL care, CHILDBIRTH, OBSTETRICS, AFRICAN Americans

مستخلص: Objectives. The objective of this study was to determine whether the length of the interval between pregnancies was associated with either preterm birth or intrauterine growth retardation in a low-income, largely Black population. Methods. The study population consisted of 4400 women who had received prenatal care in county clinics and had two consecutive singleton births between 1980 and 1990. Results. Interpregnancy intervals were positively associated with age and negatively associated with the trimester in which care was initiated in the second pregnancy. Whites had shorter intervals than non-Whites. The percentage of preterm births increased as the length of the interpregnancy interval decreased, but only for women who had not had a previous preterm birth. The association between interval and preterm birth was maintained when other factors associated with preterm birth were controlled. There was no significant relationship between intrauterine growth retardation and interpregnancy interval. Conclusions. Women, particularly those who are poor and young, should be advised of the potential harm to their infants of short interpregnancy intervals. [ABSTRACT FROM AUTHOR]

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المؤلفون: Kenyon, S L, Taylor, D J, Tarnow-Mordi, W

المصدر: Lancet. 3/31/2001, Vol. 357 Issue 9261, p989. 6p. 1 Diagram, 7 Charts.

مصطلحات موضوعية: PREMATURE labor, ANTIBIOTICS, LABOR (Obstetrics), CHILDBIRTH, DRUG efficacy

مستخلص: Interpretation: This trial provides evidence that antibiotics should not be routinely prescribed for women in spontaneous preterm labour without evidence of clinical infection. [ABSTRACT FROM AUTHOR]

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