المؤلفون: Abuduxike, Gulifeiya, Cali, Sanda, Vaizoğlu, Songül Acar, Aşut, Özen, Çavuş, Mahmut, Olgu, Musa, Çavuş, Simay Naime, Arkut, Meryem, Idehen, Blessing Oluwaseun, Almezghwi, Heyam Abdalla Saleh, Asswayeh, Hana Muftah Ali, Abawu, Janet James, Hossain, Mohammad Jayed, Almawali, Nusaiba AbdulMunaem

المصدر: Maternal & Child Health Journal; Apr2024, Vol. 28 Issue 4, p667-678, 12p

مصطلحات موضوعية: CESAREAN section, RISK assessment, PUBLIC hospitals, DELIVERY (Obstetrics), VAGINA, CYPRIOTS, SCIENTIFIC observation, PREMATURE infants, RETROSPECTIVE studies, DESCRIPTIVE statistics, CHI-squared test, AGE distribution, BIRTH rate, RESEARCH methodology, MEDICAL records, ACQUISITION of data, DATA quality, COMPARATIVE studies, DATA analysis software, TURKISH Cypriots, PREGNANCY complications, CHILDBIRTH, FETAL presentation, PREMATURE labor

مصطلحات جغرافية: ISLANDS of the Mediterranean

مستخلص: Objective: We aimed to understand the utilization of the mode of delivery and related risk factors. Further aimed to apply the Robson classification system to evaluate the data quality and analyze the CS rates in subgroups. Methods: We conducted a retrospective descriptive study by reviewing the medical records of all women who delivered at the State Hospital in 2019. A proforma was developed for extracting data from patient records. All women with six obstetric parameters were categorized into Robson groups to determine the absolute and relative contributions of each group to the overall CS rate. Results: Of 797 deliveries, 401 (50.2%) were CSs. Being older, being Turkish Cypriot, having preterm births, previous CS, multiple fetuses, and having breech or transverse fetal presentations were related to having higher risks of CS. The most common medical indication for CSs (52.3%) was a history of previous CSs. Robson Group 5 contributed the most (50.7%) to the overall CS rate, with the highest absolute contribution of 21.8%. Group 10 and Group 8 were the second and third highest contributors to the overall CS rate, with relative contributions of 25.3% and 9.0%, respectively. Conclusions: Findings revealed the substandard quality of obstetric data and a noticeably high overall CS rate. The top priority should be given to improving the quality of medical records. It underscored the necessity of implementing the Robson classification system as a standard clinical practice to enhance data quality, which helps to effectively evaluate and monitor the CS rates in obstetric populations. Significance: Caesarean section rates are increasing worldwide, and the Robson Classification System is recommended by the WHO to evaluate and monitor the CS rates. This study is the first to use Robson classifications and revealed high CS rates in specific subgroups of the obstetric population. The inadequate, substandard data quality highlighted the areas that urgently needed improvement in clinical practices at the largest state hospital. The study lays the foundation for further nationwide studies and demonstrates the importance of the Robson classification system. Specific recommendations were provided to the hospital management for improving the quality of the obstetric data and monitoring CS rates. [ABSTRACT FROM AUTHOR]

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المؤلفون: Ünal, Canan, Tanaçan, Atakan, Fadiloğlu, Erdem, Çağan, Murat, Yücesoy, Halise Meltem, Beksaç, Mehmet Sinan

المصدر: Journal of the Turkish-German Gynecological Association; Dec2023, Vol. 24 Issue 4, p241-245, 5p

مصطلحات موضوعية: OBSTRUCTIVE lung disease diagnosis, ECHOCARDIOGRAPHY, CHILDBIRTH, STATURE, LENGTH of stay in hospitals, PNEUMONIA, ACADEMIC medical centers, BODY weight, PERICARDIAL effusion, PREGNANT women, RETROSPECTIVE studies, MANN Whitney U Test, GESTATIONAL age, PREGNANCY outcomes, VITAL capacity (Respiration), PREECLAMPSIA, RISK assessment, SCOLIOSIS, SYMPTOMS, PULMONARY function tests, DESCRIPTIVE statistics, CHI-squared test, BIRTH weight, FORCED expiratory volume, HOSPITAL care, PUERPERIUM, DATA analysis software, CESAREAN section, LONGITUDINAL method, PREMATURE labor

مصطلحات جغرافية: TURKEY

مستخلص: Objective: To demonstrate the impact of scoliosis on pregnancy and gestational outcome. Material and Methods: We retrospectively evaluated gestational outcomes of pregnant women with scoliosis at Hacettepe University Hospital between 2008 and 2018. Cases were grouped according to the presence of previous scoliosis surgery and compared in terms of gestational week at birth, birthweight, rate of neonatal intensive care unit admission, hospitalization during pregnancy, route of delivery, type of anesthesia at labor and postpartum intensive care unit admission rate. Ejection fraction (EF), functional vital capacity (FVC), forced expiratory volume (FEV1) and FEV1/FVC ratio values were also recorded. Results: A total of 23 women were included, of whom 12 (52.2%) had a prior scoliosis surgery. One of the 23 (4.3%) cases was terminated due to respiratory problems, while the remaining 22 cases resulted in deliveries. The median gestational week at birth was 38.2 and the median birth weight was 3150 g. Median (range) maternal height was 143 (80-160) cm while median (range) maternal weight was 51 (35-86) kg. Three (13.6%) were diagnosed with restrictive lung disease. No significant difference was found between operated and non-operated groups in terms of respiratory function test results, cardiac EF and other related demographic and clinical features. Overall cesarean delivery rate was 63.6% (14/22) and cesarean section rate was significantly higher in the operated group (83.3% versus 40%) (p=0.04). Conclusion: Cesarean section rate was increased in this cohort of pregnancies in women with scoliosis and who had previous scoliosis surgery. [ABSTRACT FROM AUTHOR]

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المؤلفون: Litwinska, E., Syngelaki, A., Cimpoca, B., Sapantzoglou, I., Nicolaides, K. H.

المصدر: Ultrasound in Obstetrics & Gynecology; Feb2020, Vol. 55 Issue 2, p189-197, 9p

مصطلحات موضوعية: PREGNANCY, LASER endoscopy, CHILDBIRTH, PREGNANCY tests, PREMATURE labor, RESEARCH, PREMATURE infants, RESEARCH methodology, FETAL development, TWINS, RETROSPECTIVE studies, GESTATIONAL age, MEDICAL cooperation, EVALUATION research, PREGNANCY outcomes, RISK assessment, PERINATAL death, COMPARATIVE studies, BIRTH weight, RESEARCH funding, MULTIPLE pregnancy, FETAL ultrasonic imaging, SMALL for gestational age, LONGITUDINAL method

مستخلص: Objective: To investigate the value of intertwin discordance in fetal crown-rump length (CRL) at the 11-13-week scan in the prediction of adverse outcome in dichorionic (DC), monochorionic diamniotic (MCDA) and monochorionic monoamniotic (MCMA) twin pregnancies.Methods: This was a retrospective analysis of prospectively collected data on twin pregnancies undergoing routine ultrasound examination at 11-13 weeks' gestation between 2002 and 2019. In pregnancies with no major abnormalities, we examined the value of intertwin discordance in fetal CRL in DC, MCDA and MCMA twins in the prediction of fetal loss at < 20 and < 24 weeks' gestation, perinatal death at ≥ 24 weeks, preterm delivery at < 32 and < 37 weeks, birth of at least one small-for-gestational-age (SGA) neonate with birth weight < 5th percentile and intertwin birth-weight discordance of ≥ 20% and ≥ 25%.Results: First, the study population of 6225 twin pregnancies included 4896 (78.7%) DC, 1274 (20.4%) MCDA and 55 (0.9%) MCMA twin pregnancies. Second, median CRL discordance in DC twin pregnancies (3.2%; interquartile range (IQR), 1.4-5.8%) was lower than in MCDA twins (3.6%; IQR, 1.6-6.2%; P = 0.0008), but was not significantly different from that in MCMA twins (2.9%; IQR, 1.2-5.1%; P = 0.269). Third, compared to CRL discordance in DC twin pregnancies with two non-SGA live births at ≥ 37 weeks' gestation, there was significantly larger CRL discordance in both DC and MCDA twin pregnancies complicated by fetal death at < 20 and < 24 weeks' gestation, perinatal death at ≥ 24 weeks, preterm birth at < 32 and < 37 weeks, birth of at least one SGA neonate and birth-weight discordance ≥ 20% and ≥ 25%, and in MCDA twin pregnancies undergoing endoscopic laser surgery. Fourth, the predictive performance of CRL discordance for each adverse pregnancy outcome was poor, with areas under the receiver-operating-characteristics curves ranging from 0.533 to 0.624. However, in both DC and MCDA twin pregnancies with large CRL discordance, there was a high risk of fetal loss. Fifth, in DC twin pregnancies, the overall rate of fetal loss at < 20 weeks' gestation was 1.3% but, in the small subgroup with CRL discordance of ≥ 15%, which constituted 1.9% of the total, the rate increased to 5.3%. Sixth, in MCDA twin pregnancies, the rate of fetal loss or endoscopic laser surgery at < 20 weeks was about 11%, but, in the small subgroups with CRL discordance of ≥ 10%, ≥ 15% and ≥ 20%, which constituted 9%, < 3% and < 1% of the total, the risk was increased to about 32%, 49% and 70%, respectively. Seventh, in MCMA twin pregnancies, there were no significant differences in CRL discordance for any of the adverse outcome measures, but this may be the consequence of the small number of cases in the study population.Conclusions: In both DC and MCDA twin pregnancies, increased CRL discordance is associated with an increased risk of fetal death at < 20 and < 24 weeks' gestation, perinatal death at ≥ 24 weeks, preterm birth at < 37 and < 32 weeks, birth of at least one SGA neonate and birth-weight discordance ≥ 20% and ≥ 25%, but CRL discordance is a poor screening test for adverse pregnancy outcome. However, in DC twins, CRL discordance of ≥ 15% is associated with an increased risk of fetal loss at < 20 and < 24 weeks' gestation and, in MCDA twins, CRL discordance of ≥ 10%, and more so discordance of ≥ 15% and ≥ 20%, is associated with a very high risk of fetal loss or endoscopic laser surgery at < 20 and < 24 weeks and this information is useful in counseling women and defining the timing for subsequent assessment and possible intervention. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd. [ABSTRACT FROM AUTHOR]

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المؤلفون: Noehr, Bugge^1,2, Jensen, Allan^1,2, Frederiksen, Kirsten^1,2, Tabor, Ann^1,2, Kjaer, Susanne K.^1,2 susanne@cancer.dk

المصدر: Obstetrics & Gynecology. Dec2009, Vol. 114 Issue 6, p1232-1238. 7p.

مصطلحات موضوعية: *SURGICAL excision, *RISK factors in premature labor, *CERVIX uteri surgery, *RISK assessment, *CHILDBIRTH

مصطلحات جغرافية: DENMARK

مستخلص: The article presents a study which examines the depth of cervical cone excision procedure and its associated risk to preterm delivery. It states that the study includes all deliveries in Denmark from 1997-2005. It notes that 552, 678 spontaneous deliveries were eligible for analysis, 19, 049 or 3.5 percent of which were preterm. It shows that the increase in cone depth significantly associated with preterm delivery risk with 6 percent increase for every additional tissue excised.

المؤلفون: Sosta, Elena¹, Tomasoni, Lina R.², Frusca, Tiziana³, Triglia, Maria³, Pirali, Francesco⁴, El Hamad, Issa², Castelli, Francesco

المصدر: Journal of Travel Medicine. Jul/Aug2008, Vol. 15 Issue 4, p243-247. 5p. 2 Charts.

مصطلحات موضوعية: *PREMATURE infants, *PREMATURE labor, *CHILDBIRTH, *HEALTH of immigrants, *RISK assessment, *HEALTH outcome assessment

مصطلحات جغرافية: ITALY

مستخلص: Background. Various studies have ascertained different birth outcomes between resident and migrant populations in western countries. Considering preterm delivery (<37 complete weeks of gestation) as a perinatal risk condition, we assessed its rate in migrant and native Italian women who delivered in the main public hospital in Brescia (Italy). Methods. All migrant puerperas and a random sample of native puerperas hospitalized during the period February to May 2005 were included in the study after informed consent and filled in a self-administered multilanguage questionnaire enquiring about sociodemographic and obstetric data. Additional information including last menstrual period was obtained from personal obstetric records. Results. As many as 471 puerperas entered the study: 366 Italian and 105 migrant women coming from eastern Europe (41.9%), Asia (20%), South America (10.5%), and Africa (27.6%). Of the migrant population, 67 of 105 (63.8%) were at their first delivery in Italy (median interval from arrival: 3.8 y). Gestational age at delivery was assessed for 456 of 471 women (103 migrants and 353 Italians). A total of 36 (7.9%) preterm deliveries were registered: 22 (6.2%) in Italian and 14 (13.6%) in migrant puerperas ( p value = 0.015). The highest preterm delivery rate was observed in African women (20.7%), while women from eastern Europe had a similar rate to Italians. In univariate analysis, factors associated to preterm delivery were parity and length of permanence in Italy. We could not demonstrate any correlation with smoking or with a delayed access to antenatal care (first obstetric evaluation after 12 complete weeks of gestation). In multivariate analysis, African origin was the only independent risk factor for preterm delivery [odds ratio (OR) = 3.54; p = 0.018]. Conclusions. In our setting, preterm delivery occurred more frequently in migrant women, particularly of African origin, and it is not associated to delayed access to antenatal care. [ABSTRACT FROM AUTHOR]

المؤلفون: Um‐Bergström, Miranda, Papadogiannakis, Nikos, Westgren, Magnus, Vinnars, Marie‐Therese

المصدر: Acta Obstetricia et Gynecologica Scandinavica; Jan2018, Vol. 97 Issue 1, p74-81, 8p

مصطلحات موضوعية: CORTICOSTEROIDS, STEROID receptors, CHILDBIRTH, PREMATURE infants, PREGNANCY complications, PRENATAL care, PREMATURE labor, CHORIONIC villi, GESTATIONAL age, GLUCOCORTICOIDS, PLACENTA, RISK assessment, PLACENTA diseases, STATISTICS, RETROSPECTIVE studies, PREVENTION, DIAGNOSIS

مصطلحات جغرافية: SWEDEN

مستخلص: Introduction: Mothers at risk of preterm birth are treated with antenatal corticosteroids, which have advantageous effects for prematurely born infants. Accelerated villous maturation in the placenta is also associated with improved perinatal outcome. The primary aim of this study was to examine the association between antenatal corticosteroids and accelerated villous maturation. The secondary aim was to study associations with other placental pathologies.Material and Methods: A retrospective cohort study including 105 women who had (n = 75) or had not (n = 30) been treated with antenatal corticosteroids. The women gave birth between 22+0 and 26+6  weeks of gestation in Stockholm County between 1 April 2004 and 31 March 2007. A pathologist blinded to all clinical data except gestational age examined the placental slides to identify pathology parameters. The outcomes were correlated with antenatal corticosteroid treatment, and confounding factors were adjusted using logistic regression.Results: Accelerated villous maturation was significantly higher in the group treated with corticosteroids (odds ratio 16, 95% CI 2.4-690, p = 0.0005). After adjustment for gestational age and preeclampsia, the difference remained significant (odds ratio 8.9, 95% CI 1.2-389, p = 0.021). No significant associations were found regarding the secondary outcome variables, after adjusting for possible confounders.Conclusions: Antenatal corticosteroid treatment before preterm birth is associated with accelerated villous maturation. This could be one of the pathways by which corticosteroids are beneficial for preterm infants. [ABSTRACT FROM AUTHOR]

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المؤلفون: Shachar, BZ, Mayo, JA, Lyell, DJ, Baer, RJ, Jeliffe‐Pawlowski, LL, Stevenson, DK, Shaw, GM

المصدر: BJOG: An International Journal of Obstetrics & Gynaecology; Nov2016, Vol. 123 Issue 12, p2009-2017, 9p

مصطلحات موضوعية: PREGNANCY, PREGNANCY complications, CHILDBIRTH, MOTHER-child relationship, PREMATURE labor, ABORTION, BIRTH intervals, COMPARATIVE studies, GESTATIONAL age, PREMATURE infants, INFANT mortality, LONGITUDINAL method, MATERNAL age, RESEARCH methodology, EVALUATION of medical care, MEDICAL cooperation, OBESITY, PERINATAL death, RESEARCH, EVALUATION research, BODY mass index, DISEASE incidence, RETROSPECTIVE studies

مصطلحات جغرافية: CALIFORNIA

مستخلص: Objectives: We assessed whether interpregnancy interval (IPI) length after live birth and after pregnancy termination was associated with preterm birth (PTB).Design: Multiyear birth cohort.Settings: Fetal death, birth and infant death certificates in California merged with Office of Statewide Health Planning and Development.Population: One million California live births (2007-10) after live birth and after pregnancy termination.Methods: Logistic regression was used to estimate odds ratios (ORs) of PTB of 20-36 weeks of gestation and its subcategories for IPIs after a live birth and after a pregnancy termination. We used conditional logistic regression (two IPIs/mother) to investigate associations within mothers.Main Outcome Measure: PTB relative to gestations of ≥ 37 weeks.Results: Analyses included 971 211 women with IPI after live birth, and 138 405 women with IPI after pregnancy termination with 30.6% and 74.6% having intervals of <18 months, respectively. IPIs of <6 months or 6-11 months after live birth showed increased odds of PTB adjusted ORs for PTB of 1.71 (95% CI 1.65-1.78) and 1.20 (95% CI 1.16-1.24), respectively compared with intervals of 18-23 months. An IPI >36 months (versus 18-23 months) was associated with increased odds for PTB. Short IPI after pregnancy termination showed a decreased OR of 0.87 (95% CI 0.81-0.94). The within-mother analysis showed the association of increased odds of PTB for short IPI, but not for long IPI.Conclusions: Women with IPI <1 or >3 years after a live birth were at increased odds of PTB-an important group for intervention to reduce PTB. Short IPI after pregnancy termination was associated with reduced odds for PTB and needs to be further explored.Tweetable Abstract: Short and long IPI after live birth, but not after pregnancy termination, showed increased odds for PTB. [ABSTRACT FROM AUTHOR]

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المؤلفون: Whitehead, Nedra, Hill, Holly A., Brogan, Donna J., Blackmore-Prince, Cheryl

المصدر: American Journal of Epidemiology; Jan2002, Vol. 155 Issue 2, p117-124, 8p

مصطلحات موضوعية: DURATION of pregnancy, PSYCHOLOGICAL stress, PREMATURE labor, HORMONES, RISK assessment, CHILDBIRTH, LABOR complications (Obstetrics), MENTAL health, U.S. states

مصطلحات جغرافية: UNITED States

مستخلص: Biologic evidence suggests that the hormones activated by stress affect gestational length, but the results of epidemiologic investigations are inconsistent. The authors of this paper know of no threshold models that have been studied; these models assume that stress does not affect preterm delivery until a certain amount of stress has been experienced but that each unit of stress above the threshold adds to the risk of preterm delivery. By using standard logistic regression, the authors compared threshold and nonthreshold models of the relation between number of stressful life events and preterm delivery in 11 US states. They used data on 1990–1995 births from the Pregnancy Risk Assessment Monitoring System. The risk of preterm delivery among multiparas who gave birth in 1990–1993 increased 7% for each event over five they experienced, but no relation was found for 1994–1995 births. Among primiparas who gave birth in 1994–1995, the risk increased 5% for each event over two, but no relation was found for 1990–1993 births. These results suggest that a threshold model may fit the relation between stress and preterm delivery better than one with no threshold. However, the inconsistent results are difficult to reconcile with a biologic threshold in the relation between stress and preterm delivery. [ABSTRACT FROM PUBLISHER]

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المصدر: Journal of Perinatal Medicine. 2009 Supplement 1, Vol. 37, p49-50. 2p.

مصطلحات موضوعية: *PREMATURE labor, *CHILDBIRTH, *LABOR (Obstetrics), *RISK assessment, *POSTER presentations

مستخلص: The article presents poster presentations on preventing premature birth. Roberto Romero proposes that the strategy for risk assessment and prevention of preterm birth should be based on the identification of the mechanisms of obstetrical disorders responsible for preterm birth. Erich Saling discussed a study on measures to prevent premature birth at high risk.

المؤلفون: Kasman, Alex M.¹ (AUTHOR) akasman@stanford.edu, Zhang, Chiyuan A.¹ (AUTHOR), Li, Shufeng¹ (AUTHOR), Stevenson, David K.² (AUTHOR), Shaw, Gary M.² (AUTHOR), Eisenberg, Michael L.^1,3 (AUTHOR)

المصدر: Fertility & Sterility. May2020, Vol. 113 Issue 5, p947-954. 8p.

مصطلحات موضوعية: *ECLAMPSIA, *PERIPARTUM cardiomyopathy, *PREMATURE labor, *CHILDBIRTH, *GESTATIONAL diabetes, *LOW birth weight, *INTENSIVE care units, *LENGTH of stay in hospitals, *DATABASES, *PREMATURE infants, *NEONATAL intensive care, *TIME, *HEALTH status indicators, *FATHERS, *GESTATIONAL age, *DISEASE incidence, *RETROSPECTIVE studies, *NEONATAL intensive care units, *RISK assessment, *PREGNANCY complications, *BIRTH weight, *COMORBIDITY

مصطلحات جغرافية: UNITED States

الشركة/الكيان: INTERNATIONAL Business Machines Corp. 001368083 IBM

الملخص (بالإنجليزية): Objective: To assess whether paternal health is associated with maternal peripartum and neonatal outcomes.Design: Retrospective cohort study.Setting: University research departments.Patient(s): Analytic sample of children born to paired fathers and mothers covering live births within the United States between 2009-2016.Intervention(s): Paternal health status (e.g., metabolic syndrome diagnoses, individual chronic disease diagnoses).Main Outcome Measure(s): Primary outcome of preterm birth (i.e., live birth before 37 weeks), and secondary outcomes of low birth weight, neonatal intensive care unit (NICU) stay, gestational diabetes, preeclampsia, eclampsia, and length of maternal stay.Result(s): The IBM Marketscan Research database covers reimbursed health care claims data on inpatient and outpatient encounters who are privately insured through employment-sponsored health insurance. We assessed 785,809 singleton live births, with 6.6% born preterm. The presence of paternal comorbidities was associated with higher odds of preterm birth, low birth weight (LBW), and NICU stay. After adjusting for maternal factors, fathers with most or all components of the metabolic syndrome had 19% higher odds of having a child born preterm (95% CI 1.11-1.28), 23% higher odds of LBW (95% CI 1.01-1.51), and 28% higher odds of NICU stay (95% CI 1.08-1.52). Maternal morbidity (e.g., gestational diabetes or preeclampsia) was also positively associated with preconception paternal health.Conclusion(s): Increased preconception paternal comorbidity may be associated with negative infant and maternal outcomes. Although the paternal effect remains modest, these findings highlight the importance of the health of both parents, particularly the mother, on healthy pregnancy. [ABSTRACT FROM AUTHOR]

Abstract (Spanish): Asociación entre la salud preconcepcional del varón sobre los resultados perinatales: estudio de datos de solicitudes de reembolso en EE.UU Evaluar si la salud del varón está asociada con los resultados maternos periparto y neonatales. Estudio de cohorte retrospectiva. Departamentos de investigación universitarios. Muestra analítica de hijos nacidos de padres y madres emparejados que cubre los nacimientos en Estados Unidos entre 2009 y 2016. Estado de salud de los progenitores (e.g. diagnóstico de síndrome metabólico, diagnósticos de enfermedades crónicas individuales). Resultado primario: nacimiento pretérmino (i.e. nacido vivo antes de la semana 37) y resultados secundarios: bajo peso, estancia en unidad de cuidados intensivos neonatales (NICU), diabetes gestacional, preeclampsia, eclampsia y duración de la estancia materna. La base de datos IBM Marketscan Research abarca los datos de las solicitudes de reembolso de actos médicos en pacientes ingresados y ambulatorios con seguro médico privado pagado por el empleador. Evaluamos 785.809 partos únicos con recién nacido vivo, con 6,6% nacidos pretérmino. La presencia de comorbilidades paternas se asoció con una mayor probabilidad de parto pretérmino, bajo peso al nacer (LBW) y estancia en NICU. Tras ajustar por factores maternos, los padres con la mayoría o todos los componentes del síndrome metabólico tuvieron un riesgo un 19% mayor de tener un hijo pretérmino (IC 95% 1.11—1.28), un riesgo un 23% mayor de LBW (IC 95% 1.01—1.51) y un riesgo un 28% mayor de estancia en NICU (IC 95% 1.08—1.52). La morbilidad materna (e.g., diabetes gestacional o preeclampsia) también estuvo asociada positivamente con la salud paterna preconcepcional. El aumento de comorbilidades preconcepcionales en el varón puede estar asociado con resultados negativos maternos y en neonatos. Aunque el efecto paterno es modesto, estos resultados resaltan la importancia de la salud de ambos progenitores, sobre todo la madre, para un embarazo saludable. [ABSTRACT FROM AUTHOR]