المؤلفون: Gruber, Teresa Mira, Ortlieb, Laura, Henrich, Wolfgang, Mechsner, Sylvia

المصدر: Journal of Clinical Medicine; Jan2024, Vol. 13 Issue 2, p414, 11p

مصطلحات موضوعية: PREGNANCY complications, CHILDBIRTH, PLACENTA praevia, PREMATURE labor, MATERNAL age, ENDOMETRIOSIS, PELVIC pain

مستخلص: Women with endometriosis (EM), particularly the manifestations of adenomyosis (AM) and deep infiltrating endometriosis (DIE), suffer from pain and sterility. DIE also appears with several specific obstetric complications. To determine the risk profile, we designed a retrospective case–control study. Primary outcomes were defined as the risk of preterm birth and caesarean delivery (CD). Primiparous singleton pregnancies in women with DIE were compared with controls without EM. We matched for mode of conception and maternal age. A total of 41 women diagnosed with DIE and 164 controls were recruited. A total of 92.7% of the cases were also diagnosed with AM. Preterm birth occurred in 12.2% of cases and in 6.7% of controls. The difference was not statistically significant (OR: 1.932; 95% CI: 0.632–5.907). The rate of CD was similar in both groups. Remarkably, placental implantation disorders in the form of placenta praevia were eight times more frequent in women with DIE (9.8%) than in controls (1.2%, OR: 8.757; 95% CI: 1.545–49.614). Neonatal outcome was similar in both groups. Four out of fourteen cases reported abdominal wall endometriosis after CD. Women with DIE/AM and with placenta praevia are at risk of bleeding complications. After CD, they can develop abdominal wall EM. We therefore suggest evaluating the birth mode in each woman with DIE/AM. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Clinical Medicine is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Yim, Gyeyoon^1,2 (AUTHOR), Roberts, Andrea² (AUTHOR), Wypij, David^3,4,5 (AUTHOR), Kioumourtzoglou, Marianthi-Anna⁶ (AUTHOR), Weisskopf, Marc G^1,2 (AUTHOR) mweissko@hsph.harvard.edu

المصدر: International Journal of Epidemiology. Dec2021, Vol. 50 Issue 6, p1886-1896. 11p.

مصطلحات موضوعية: *LOW birth weight, *PREMATURE labor, *CHILDBIRTH, *PREGNANCY complications, *PREGNANCY

مستخلص: Background: Diethylstilbestrol (DES) is an endocrine-disrupting pharmaceutical prescribed to pregnant women to prevent pregnancy complications between the 1940s and 1970s. Although DES has been shown in animal studies to have multigenerational effects, only two studies have investigated potential multigenerational effects in humans on preterm birth (PTB), and none on low birthweight (LBW)-major determinants of later life health.Methods: Nurses' Health Study (NHS) II participants (G1; born 1946-64) reported their mothers' (G0) use of DES while pregnant with them. We used cluster-weighted generalized estimating equations to estimate odds ratios (OR) and 95% confidence intervals (CI) for risk of LBW and PTB among the grandchildren by grandmother use of DES. G1 birthweight and gestational age were considered to explore confounding by indication.Results: Among 54 334 G0-G1/grandmother-mother pairs, 973 (1.8%) G0 used DES during pregnancy with G1. Of the 128 275 G2 children, 4369 (3.4%) were LBW and 7976 (6.2%) premature. Grandmother (G0) use of DES during pregnancy was associated with an increased risk of G2 LBW [adjusted OR (aOR) = 3.09; 95% CI: 2.57, 3.72], that was reduced when restricted to term births (aOR = 1.59; 95% CI: 1.08, 2.36). The aOR for PTB was 2.88 (95% CI: 2.46, 3.37). Results were essentially unchanged when G1 birthweight and gestational age were included in the model, as well as after adjusting for other potential intermediate variables, such as G2 pregnancy-related factors.Conclusions: Grandmother use of DES during pregnancy is associated with an increased risk of LBW, predominantly through an increased risk of PTB. Results when considering G1 birth outcomes suggest this does not result from confounding by indication. [ABSTRACT FROM AUTHOR]

العنوان البديل: RETROSPEKTIVNO ISTRAŽIVANJE PRIJEVREMENIH POROĐAJA U STAVU ZATKOM U RAZDOBLJU OD 26 GODINA.

المؤلفون: Starčević, Vito¹ vito.starcevic@gmail.com, Ivanišević, Marina¹, Herman, Mislav¹, Starčević, Tea¹, Juras, Josip¹, Tuškan, Ksenija¹, Đelmiš, Josip¹, Sokol-Karadjole, Vesna¹, Magdić, Mihaela¹, Horvatiček, Marina²

المصدر: Gynaecologia et Perinatologia. Jan-Jun2018, Vol. 27 Issue 1/2, p9-13. 5p.

مصطلحات موضوعية: *BREECH delivery, *PREMATURE labor, *CESAREAN section, *CHILDBIRTH, *EARLY death, *INTRAVENTRICULAR hemorrhage, *ASPHYXIA neonatorum

الملخص (بالإنجليزية): Breech presentation is childbirth, during which may be expected higher perinatal mortality and morbidity when compared to cephalic presentation. The breech presentation complicates 20-35 % of preterm delivery. This group of neonates is exposed to hypoxic damages, as well as birth injuries with consequent intracranial hemorrhages. The mortality rate of preterm infants is much higher than the mortality of full-term infants. A higher risk of perinatal asphyxia and birth trauma makes obstetricians decide for operative completion by Cesarean section. Research methods. We conducted a retrospective study and analyzed and compared perinatal categories: perinatal mortality and morbidity, the mode of pregnancy completion, and the incidence of Cesarean section and vaginal delivery in six periods. Patients and research methods. The studied material was collected for the period of the past 26 years from the archives in the Department of Obstetrics and Gynecology. All singleton pregnancies with the breech presentation were analyzed, delivered either vaginally or by Cesarean section. Results. The incidence of Cesarean sections in preterm births with breech presentation gradually grows through the studied period. Obstetricians were increasingly opting for a Cesarean section in the situation of preterm birth and breech presentation, to eliminate traumatic and hypoxic damage, and thus tried to reduce perinatal mortality. The perinatal mortality rate of premature fetuses in a breech presentation who were delivered vaginally, according to numerous authors was statistically significantly higher compared to the perinatal mortality of premature neonates who were delivered by Cesarean section. Conclusion. The research emphasizes the importance of the completion of the premature birth of a child in the breech presentation by Cesarean section if the child is alive and there are no identifiable development defects. [ABSTRACT FROM AUTHOR]

Abstract (Croatian): Stav zatkom predstavlja prezentaciju čeda, kod koje možemo očekivati veći perinatalni mortalitet i morbiditet u odnosu na stav glavicom. Učestalost prijevremenih porođaja u stavu zatkom kreće se od 20-35%. Tako prijevremeno porođena djeca izloženija su hipoksičnim oštećenjima, kao i traumatskim ozljedama s posljedičnim intrakranijalnim hemoragijama. Smrtnost nedonoščadi je višestruko veća od smrtnosti donošene djece. Veći rizik od perinatalne asfiksije i porođajne traume češće rezultira s većom učestalosti operativnog dovršenja porođaja carskim rezom, za koji se češće odlučuju porodničari. Metode istraživanja. Provedena je retrospektivna studija kroz šest velikih razdoblja, gdje je uspoređen perinatalni mortalitet i morbiditet, način dovršenja trudnoće, kao i učestalost carskih rezova i vaginalnih porođaja. Ispitanice i način istraživanja provedenog tijekom 26 godina bile su sve jednoplodne trudnoće s djetetom u stavu zatkom, završene carskim rezom. Rezultati. Učestalost carskih rezova kod prijevremenih porođaja zatkom postupno raste kroz istraživana razdoblja. Porodničari se sve češće odlučuju za carski rez kod prijevremenih porođaja djece u stavu zatkom, kako bi eliminirali traumatsko i hipoksično oštećenje, te tako pokušali smanjiti perinatalni mortalitet. Perinatalni mortalitet vaginalnih porođaja prijevremeno porođene djece u stavu zatkom, prema brojnim autorima je statistički znakovito veći, od perinatalnog mortaliteta prijevremeno porođene djece carskim rezom. Zaključak. Provedeno istraživanje nas upućuje na važnost dovršenja prijevremenog porođaja djeteta u stavu zatkom carskim rezom, ako je dijete živo i nema prepoznatljive mane razvitka. [ABSTRACT FROM AUTHOR]

المؤلفون: Castañon, A¹, Landy, R¹, Brocklehurst, P², Evans, H³, Peebles, D², Singh, N⁴, Walker, P³, Patnick, J⁵, Sasieni, P¹

المصدر: BJOG: An International Journal of Obstetrics & Gynaecology. Aug2015, Vol. 122 Issue 9, p1191-1199. 9p. 1 Diagram, 2 Charts, 1 Graph.

مصطلحات موضوعية: *RISK factors in premature labor, *SURGICAL excision, *CERVICAL intraepithelial neoplasia, *CHILDBIRTH, *COLPOSCOPY, *CASE-control method, *SUBSEQUENT pregnancy

مستخلص: Objective To explore whether the increased risk of preterm birth following treatment for cervical disease is limited to the first birth following colposcopy. Design Nested case-control study. Setting Twelve NHS hospitals in England. Population All nonmultiple births from women selected as cases or controls from a cohort of women with both colposcopy and a hospital birth. Cases had a preterm (20-36 weeks of gestation) birth. Controls had a term birth (38-42 weeks) and no preterm. Methods Obstetric, colposcopy and pathology details were obtained. Main outcome measures Adjusted odds ratio of preterm birth in first and second or subsequent births following treatment for cervical disease. Results A total of 2798 births (1021 preterm) from 2001 women were included in the analysis. The risk of preterm birth increased with increasing depth of treatment among first births post treatment [trend per category increase in depth, categories <10 mm, 10-14 mm, 15-19 mm, ≥20 mm: odds ratio ( OR) 1.23, 95% confidence interval (95% CI) 1.12-1.36, P < 0.001] and among second and subsequent births post treatment (trend OR 1.34, 95% CI 1.15-1.56, P < 0.001). No trend was observed among births before colposcopy ( OR 0.98, 95% CI 0.83-1.16, P = 0.855). The absolute risk of a preterm birth following deep treatments (≥15 mm) was 6.5% among births before colposcopy, 18.9% among first births and 17.2% among second and subsequent births post treatment. Risk of preterm birth (once depth was accounted for) did not differ when comparing first births post colposcopy with second and subsequent births post colposcopy (adjusted OR 1.15, 95% CI 0.89-1.49). Conclusions The increased risk of preterm birth following treatment for cervical disease is not restricted to the first birth post colposcopy; it remains for second and subsequent births. These results suggest that once a woman has a deep treatment she remains at higher risk of a preterm birth throughout her reproductive life. Tweetable abstract Risk of preterm birth following large treatments for cervical disease remains for second and subsequent births. [ABSTRACT FROM AUTHOR]

المؤلفون: Papanna, R.¹, Mann, L. K.¹, Baschat, A. A.², Bebbington, M. W.¹, Khalek, N.³, Johnson, A.¹, Snowise, S.¹, Moise, K. J.¹

المصدر: Ultrasound in Obstetrics & Gynecology. Feb2015, Vol. 45 Issue 2, p175-182. 8p.

مصطلحات موضوعية: *PREMATURE labor, *DELIVERY (Obstetrics), *CHILDBIRTH, *OBSTETRICS, *LABOR (Obstetrics), *LASER surgery

مستخلص: ABSTRACT Objectives To determine the risk factors for spontaneous preterm delivery ( PTD) or preterm prelabor rupture of membranes ( PPROM) at < 34 weeks' gestation after fetoscopic laser surgery for twin-twin transfusion syndrome and to identify the optimal threshold for preoperative cervical length ( CL) that indicates a high risk for spontaneous PTD. Methods This was a secondary analysis of data prospectively collected from 449 patients at three fetal centers. CL measurements were obtained by preoperative transvaginal ultrasound, at a gestational age of 16-26 weeks. The risk factors associated with spontaneous PTD before 34 weeks' gestation were determined using multivariable logistic regression analysis. We excluded patients with dual fetal demise and those with maternal or fetal indications for delivery without PPROM ( n = 63). The optimal threshold for cervical length to predict spontaneous PTD before 34 weeks was determined using a receiver-operating characteristics ( ROC) curve and Youden index. Additionally, the CL threshold for spontaneous PTD at 2-week intervals between 24 and 34 weeks was determined. Results Spontaneous PTD before 34 weeks occurred in 206 (53.4%) of the included patients. Only the preoperative CL was significantly associated with spontaneous PTD. The preoperative CL was normally distributed with a mean of 37.6 ± 10.3 mm (range, 5-66 mm). Maternal age and parity were positively associated, and gestational age at procedure and anterior placenta were negatively associated, with CL on multivariable linear regression analysis. The area under the ROC curve for predicting spontaneous PTD with CL measurements was 0.61 ( P = 0.02) and the optimal threshold was 28 mm with a Youden index of 0.19 (sensitivity and specificity of 92% and 27%, respectively). A CL measurement of < 28 mm increased the risk of spontaneous PTD for all gestational age thresholds. Conclusions Spontaneous PTD at < 34 weeks' gestation is associated with a preoperative CL of < 28 mm. Preventive strategies should focus on this high-risk group. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd. [ABSTRACT FROM AUTHOR]

المؤلفون: Oluwole, Ayodeji A.¹, Adegbesan-Omilabu, Maymunah A.¹, Okunade, Kehinde S.¹ kehindeokunade@gmail.com

المصدر: Nigerian Medical Journal. Sep/Oct2014, Vol. 55 Issue 5, p406-410. 5p.

مصطلحات موضوعية: *PREMATURE labor, *DELIVERY (Obstetrics), *CHILDBIRTH, *CHOLESTEROL, *ISOPENTENOIDS

مستخلص: Background: The study assessed whether low maternal serum cholesterol during early pregnancy is associated with preterm delivery. Patients and Methods: It was a prospective observational cohort study involving pregnant women at gestational age of 14-20 weeks over a period of 12 months. Blood samples were obtained to measure total serum cholesterol concentrations and the sera were then analysed enzymatically by the cholesterol oxidase: p-aminophenazone (CHOD PAP) method. Results: The study showed an incidence of 5.0% for preterm delivery in the low risk study patients. Preterm birth was 4.83-times more common with low total maternal cholesterol than with midrange total cholesterol (11.8% versus 2.2%, P = 0.024). Conclusion: Low maternal serum cholesterol (hypocholesterolaemia) is associated with preterm delivery. Optimal maternal serum cholesterol during pregnancy may have merit, therefore pregnant women should be encouraged to follow a healthy, balanced diet. [ABSTRACT FROM AUTHOR]

المؤلفون: Barrett, Peter M., McCarthy, Fergus P., Evans, Marie, Kublickas, Marius, Perry, Ivan J., Stenvinkel, Peter, Kublickiene, Karolina, Khashan, Ali S.

المصدر: BMC Medicine; 4/1/2020, Vol. 18 Issue 1, p1-12, 12p, 4 Charts, 2 Graphs

مصطلحات موضوعية: KIDNEY diseases, CHRONIC kidney failure, LABOR complications (Obstetrics), CHILDBIRTH, PREMATURE labor, DISEASE risk factors, WOMEN'S health

مستخلص: Background: Preterm delivery is an independent risk factor for maternal cardiovascular disease. Little is known about the association between preterm delivery and maternal renal function. This study aimed to examine whether women who experience preterm delivery are at increased risk of subsequent chronic kidney disease (CKD) and end-stage kidney disease (ESKD).Methods: Using data from the Swedish Medical Birth Register, singleton live births from 1973 to 2012 were identified and linked to data from the Swedish Renal Register and National Patient Register (up to 2013). Gestational age at delivery was the main exposure and treated as a time-dependent variable. Primary outcomes were maternal CKD or ESKD. Cox proportional hazard regression models were used for analysis.Results: The dataset included 1,943,716 women who had 3,760,429 singleton live births. The median follow-up was 20.6 (interquartile range 9.9-30.0) years. Overall, 162,918 women (8.4%) delivered at least 1 preterm infant (< 37 weeks). Women who had any preterm delivery (< 37 weeks) were at increased risk of CKD (adjusted hazard ratio (aHR) 1.39, 95% CI 1.32-1.45) and ESKD (aHR 2.22, 95% CI 1.90-2.58) compared with women who only delivered at term (≥ 37 weeks). Women who delivered an extremely preterm infant (< 28 weeks) were at increased risk of CKD (aHR 1.84, 95% CI 1.52-2.22) and ESKD (aHR 3.61, 95% CI 2.03-6.39). The highest risk of CKD and ESKD was in women who experienced preterm delivery + preeclampsia (vs. non-preeclamptic term deliveries, for CKD, aHR 2.81, 95% CI 2.46-3.20; for ESKD, aHR 6.70, 95% CI 4.70-9.56). However, spontaneous preterm delivery was also associated with increased risk of CKD (aHR 1.32, 95% CI 1.25-1.39) and ESKD (aHR 1.99, 95% CI 1.67-2.38) independent of preeclampsia or small for gestational age (SGA).Conclusions: Women with history of preterm delivery are at increased risk of CKD and ESKD. The risk is higher among women who had very preterm or extremely preterm deliveries, or whose preterm delivery was medically indicated. Women who experience spontaneous preterm delivery are at increased risk of long-term renal disease independent of preeclampsia or SGA. Preterm delivery may act as a risk marker for adverse maternal renal outcomes. [ABSTRACT FROM AUTHOR]

: Copyright of BMC Medicine is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Jakobsson, M.¹ maija.jakobsson@fimnet.fi, Gissler, M.², Paavonen, J.¹, Tapper, A.-M.¹

المصدر: BJOG: An International Journal of Obstetrics & Gynaecology. Jan2008, Vol. 115 Issue 1, p38-43. 6p. 3 Charts.

مصطلحات موضوعية: *RISK factors in premature labor, *PREMATURE labor, *CHILDBIRTH, *OBSTETRICS

مصطلحات جغرافية: FINLAND

مستخلص: Objective We examined the trends and risk factors of preterm delivery. Design Register-based retrospective cohort study from Finland. Setting National Medical Birth Register data during 1987–2005. Population The study population consisted of 1 137 515 deliveries, of which 59 025 were preterm (5.2%). Methods We calculated the population attributable risks for using the risk factor prevalence rates in the population. We further calculated odds ratios with 95% CI by multivariate logistic regression to adjust for confounders. Main outcome measures Preterm delivery rate subclassified into moderately preterm (32–36 weeks), very preterm (28–31 weeks) and extremely preterm (less than 28 weeks). Results Preterm delivery rates increased from 5.1% in the late 1980s to 5.4% in the late 1990s but then decreased to 5.2% for 2001–05. The proportion of extremely preterm deliveries decreased substantially by 12% ( P < 0.01). The greatest risk factors were multiplicity (OR 13.72, 95% CI 13.26–14.19), followed by elective delivery (OR 1.86, 95% CI 1.82–1.89), primiparity (OR 1.47, 95% CI 1.45–1.50), in vitro fertilisation treatment (OR 1.39, 95% CI 1.31–1.47), maternal smoking (OR 1.31, 95% CI 1.29–1.34) and advanced maternal age (OR 1.02, 95% CI 1.02–1.03 for each additional year of age). Prematurity rates decreased by 1.8% after adjusting for risk variables. Conclusions The rate of preterm delivery has not increased from 1987 to 2005 in Finland, while the risk for extremely preterm delivery has decreased. This finding is in contrast with recent trends in other countries. [ABSTRACT FROM AUTHOR]

المؤلفون: Rempis, Eva M., Schnack, Alexandra, Decker, Sarah, Braun, Vera, Rubaihayo, John, Tumwesigye, Nazarius Mbona, Busingye, Priscilla, Harms, Gundel, Theuring, Stefanie

المصدر: BMC Pregnancy & Childbirth; 3/7/2017, Vol. 17, p1-12, 12p

مصطلحات موضوعية: PREGNANT women, HIV prevention, CHILDBIRTH, STILLBIRTH, PREMATURE labor, PUBLIC health, HIV infection transmission, VERTICAL transmission (Communicable diseases), ANTI-HIV agents, BIRTH size, COMMUNICABLE diseases, HIV infections, PREMATURE infants, PERINATAL death, PREGNANCY complications, PRENATAL care, CROSS-sectional method, PREVENTION

مصطلحات جغرافية: UGANDA

مستخلص: Background: While most Sub-Saharan African countries are now implementing the WHO-recommended Option B+ protocol for prevention of vertical HIV transmission, there is a lack of knowledge regarding the influence of Option B+ exposure on adverse birth outcomes (ABOs). Against this background, we assessed ABOs among delivering women in Western Uganda.Methods: A cross-sectional, observational study was performed within a cohort of 412 mother-newborn-pairs in Virika Hospital, Fort Portal in 2013. The occurrence of stillbirth, pre-term delivery, and small size for gestational age (SGA) was analysed, looking for influencing factors related to HIV-status, antiretroviral drug exposure and duration, and other sociodemographic and clinical parameters.Results: Among 302 HIV-negative and 110 HIV-positive women, ABOs occurred in 40.5%, with stillbirth in 6.3%, pre-term delivery in 28.6%, and SGA in 12.2% of deliveries. For Option B+ intake (n = 59), no significant association was found with stillbirth (OR 0.48, p = 0.55), pre-term delivery (OR 0.97, p = 0.92) and SGA (OR 1.5, p = 0.3) compared to seronegative women. Women enrolled on antiretroviral therapy (ART) before conception (n = 38) had no different risk for ABOs than women on Option B+ or HIV-negative women. Identified risk factors for stillbirth included lack of formal education, poor socio-economic status, long travel distance, hypertension and anaemia. Pre-term delivery risk was increased with poor socio-economic status, primiparity, Malaria and anaemia. The occurrence of SGA was influenced by older age and Malaria.Conclusion: In our study, women on Option B+ showed no difference in ABOs compared to HIV-negative women and to women on ART. We identified several non-HIV/ART-related influencing factors, suggesting an urgent need for improving early risk assessment mechanisms in antenatal care through better screening and triage systems. Our results are encouraging with regard to continued universal scale-up of Option B+ and ART programmes. [ABSTRACT FROM AUTHOR]

: Copyright of BMC Pregnancy & Childbirth is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Aviram, Amir, Hiersch, Liran, Ashwal, Eran, Yogev, Yariv, Hadar, Eran

المصدر: Journal of Maternal-Fetal & Neonatal Medicine; Sep2016, Vol. 29 Issue 18, p2897-2903, 7p

مصطلحات موضوعية: UTERINE contraction, LABOR pain (Obstetrics), ELECTROMYOGRAPHY, DELIVERY (Obstetrics), CHILDBIRTH, CERVIX uteri physiology, GESTATIONAL age, PREMATURE labor, LONGITUDINAL method, PATIENT monitoring, REGRESSION analysis, TIME

مستخلص: Objective: To assess the association between myometrial electrical activity and time-to-delivery in preterm labor using uterine electromyography.Methods: Myometrial electrical activity was measured via the electrical uterine monitor (EUM) device. Data was prospectively collected among women admitted due to suspected preterm labor, prior to 34 weeks of gestation. EUM-Index was defined as the mean electrical activity of the uterine muscle over a period of 10 minutes measured in units of microjoule (μJ, microwatt second). The association between the EUM-Index at admission to time-to-delivery and delivery prior to 34 weeks of gestation was calculated.Results: Overall, 45 women were included in the study. EUM-Index combined with cervical dilatation, demonstrated significant correlation to time-to-delivery (R(2 )= 0.49, p = 0.005), which was strengthened for women presenting prior to 28 weeks of gestation. EUM-Index above the median (>3.05 MJ) was significantly associated with a shorter latency period for delivery (36.0 ± 19.4 vs. 50.2 ± 25.9 days, p = 0.04). For delivery prior to 34 weeks, the EUM-Index showed an AUC = 0.65 (95% CI 0.48-0.82), and a cutoff of 2.5 MJ provided 91.7% sensitivity and 93.3% negative predictive value.Conclusion: EUM-Index at time of admission due to suspected preterm labor is inversely correlated with time-to-delivery and may effectively rule out preterm delivery prior to 34 weeks. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Maternal-Fetal & Neonatal Medicine is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)