المؤلفون: Qin, Wei^1,2 (AUTHOR), Shao, Ling^1,3 (AUTHOR), Wang, Jun² (AUTHOR), Zhang, Huan² (AUTHOR), Wang, Yao² (AUTHOR), Zhang, Xiaqing^2,4 (AUTHOR), Xie, Shaoyu² (AUTHOR), Pan, Fan² (AUTHOR), Cheng, Kai² (AUTHOR), Ma, Liguo² (AUTHOR), Chen, Yafei² (AUTHOR), Song, Jian¹ (AUTHOR), Gao, Dawei⁵ (AUTHOR), Chen, Zhichao⁵ (AUTHOR), Yang, Wei⁵ (AUTHOR), Zhu, Rui⁵ (AUTHOR), Su, Hong¹ (AUTHOR) suhong5151@sina.com

المصدر: Journal of Viral Hepatitis. Mar2024, Vol. 31 Issue 3, p143-150. 8p.

مصطلحات موضوعية: *PREMATURE labor, *LOW birth weight, *HEPATITIS B vaccines, *CHILDBIRTH, *PREMATURE infants, *BOOSTER vaccines

مستخلص: Previous studies did not provide substantial evidence for long‐term immune persistence after the hepatitis B vaccine (HepB) in preterm birth (PTB) children. Consequently, there is ongoing controversy surrounding the booster immunization strategy for these children. Therefore, we conducted a retrospective cohort study to evaluate the disparities in immune persistence between PTB children and full‐term children. A total of 1027 participants were enrolled in this study, including 505 PTB children in the exposure group and 522 full‐term children in the control group. The negative rate of hepatitis B surface antibody (HBsAb) in the PTB group was significantly lower than that in the control group (47.9% vs. 41.4%, p =.035). The risk of HBsAb‐negative in the exposure group was 1.5 times higher than that in the control group (adjusted odds ratio [aOR] = 1.5, 95% confidence interval [CI]: 1.1–2.0). The geometric mean concentration (GMC) of HBsAb was much lower for participants in the exposure group compared to participants in the control group (9.3 vs. 12.4 mIU/mL, p =.029). Subgroup analysis showed that the very preterm infants (gestational age <32 weeks) and the preterm low birth weight infants (birth weight <2000 g) had relatively low GMC levels of 3.2 mIU/mL (95% CI: 0.9–11.1) and 7.9 mIU/mL (95% CI: 4.2–14.8), respectively. Our findings demonstrated that PTB had a significant impact on the long‐term persistence of HBsAb after HepB vaccination. The very preterm infants (gestational age <32 weeks) and the preterm low birth weight infants (birth weight <2000 g) may be special populations that should be given priority for HepB booster vaccination. [ABSTRACT FROM AUTHOR]

المؤلفون: Abuduxike, Gulifeiya, Cali, Sanda, Vaizoğlu, Songül Acar, Aşut, Özen, Çavuş, Mahmut, Olgu, Musa, Çavuş, Simay Naime, Arkut, Meryem, Idehen, Blessing Oluwaseun, Almezghwi, Heyam Abdalla Saleh, Asswayeh, Hana Muftah Ali, Abawu, Janet James, Hossain, Mohammad Jayed, Almawali, Nusaiba AbdulMunaem

المصدر: Maternal & Child Health Journal; Apr2024, Vol. 28 Issue 4, p667-678, 12p

مصطلحات موضوعية: CESAREAN section, RISK assessment, PUBLIC hospitals, DELIVERY (Obstetrics), VAGINA, CYPRIOTS, SCIENTIFIC observation, PREMATURE infants, RETROSPECTIVE studies, DESCRIPTIVE statistics, CHI-squared test, AGE distribution, BIRTH rate, RESEARCH methodology, MEDICAL records, ACQUISITION of data, DATA quality, COMPARATIVE studies, DATA analysis software, TURKISH Cypriots, PREGNANCY complications, CHILDBIRTH, FETAL presentation, PREMATURE labor

مصطلحات جغرافية: ISLANDS of the Mediterranean

مستخلص: Objective: We aimed to understand the utilization of the mode of delivery and related risk factors. Further aimed to apply the Robson classification system to evaluate the data quality and analyze the CS rates in subgroups. Methods: We conducted a retrospective descriptive study by reviewing the medical records of all women who delivered at the State Hospital in 2019. A proforma was developed for extracting data from patient records. All women with six obstetric parameters were categorized into Robson groups to determine the absolute and relative contributions of each group to the overall CS rate. Results: Of 797 deliveries, 401 (50.2%) were CSs. Being older, being Turkish Cypriot, having preterm births, previous CS, multiple fetuses, and having breech or transverse fetal presentations were related to having higher risks of CS. The most common medical indication for CSs (52.3%) was a history of previous CSs. Robson Group 5 contributed the most (50.7%) to the overall CS rate, with the highest absolute contribution of 21.8%. Group 10 and Group 8 were the second and third highest contributors to the overall CS rate, with relative contributions of 25.3% and 9.0%, respectively. Conclusions: Findings revealed the substandard quality of obstetric data and a noticeably high overall CS rate. The top priority should be given to improving the quality of medical records. It underscored the necessity of implementing the Robson classification system as a standard clinical practice to enhance data quality, which helps to effectively evaluate and monitor the CS rates in obstetric populations. Significance: Caesarean section rates are increasing worldwide, and the Robson Classification System is recommended by the WHO to evaluate and monitor the CS rates. This study is the first to use Robson classifications and revealed high CS rates in specific subgroups of the obstetric population. The inadequate, substandard data quality highlighted the areas that urgently needed improvement in clinical practices at the largest state hospital. The study lays the foundation for further nationwide studies and demonstrates the importance of the Robson classification system. Specific recommendations were provided to the hospital management for improving the quality of the obstetric data and monitoring CS rates. [ABSTRACT FROM AUTHOR]

: Copyright of Maternal & Child Health Journal is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Kramer, Boris W., Abman, Steven, Daly, Mandy, Jobe, Alan H., Niklas, Victoria

المصدر: Paediatric Respiratory Reviews; Dec2023, Vol. 48, p24-29, 6p

مصطلحات موضوعية: LUNG development, PREMATURE labor, SOMATOMEDIN C, CHILDBIRTH, PREMATURE infants, MECONIUM aspiration syndrome, CARDIOVASCULAR diseases

مستخلص: The past decades have seen markedly improved survival of increasingly immature preterm infants, yet major health complications persist. This is particularly true for bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity, which has become the most common sequelae of prematurity and a significant predictor of respiratory morbidity throughout childhood as well as adult life, neurodevelopmental disability, cardiovascular disease, and even death. The need for novel approaches to reduce BPD and related complications of prematurity has never been more critical. Thus, despite major advances in the use of antenatal steroids, surfactant therapy, and improvements in respiratory support, there is a persistent need for developing therapeutic strategies that more specifically reflect our growing understanding of BPD in the post-surfactant age, or the "new BPD." In contrast with the severe lung injury leading to marked fibroproliferative disease from the past, the "new BPD" is primarily characterized by an arrest of lung development as related to more extreme prematurity. This distinction and the continued high incidence of BPD and related sequelae suggest the need to identify therapies that target critical mechanisms that support lung growth and maturation in conjunction with treatments to improve respiratory outcomes across the lifespan. As the prevention of BPD and its severity remains a primary goal, we highlight the concept from preclinical and early clinical observations that insulin-like growth factor 1 (IGF-1) can potentially support the natural sequence of lung growth as a replacement therapy after preterm birth. Data supporting this hypothesis are robust and include observations that low IGF-1 levels persist after extremely preterm birth in human infants and strong preclinical data from experimental models of BPD highlight the therapeutic benefit of IGF-1 in reducing disease. Importantly, phase 2a clinical data in extremely premature infants where replacement of IGF-1 with a human recombinant human IGF-1 complexed with its main IGF-1 binding protein 3, significantly reduced the most severe form of BPD, which is strongly associated with multiple morbidities that have lifelong consequences. As physiologic replacement therapy of surfactant heralded the success of reducing acute respiratory distress syndrome in preterm infants, the paradigm has the potential to become the platform for discovering the next generation of therapies like IGF-1, which becomes deficient after extremely premature birth where endogenous production by the infant is not sufficient to maintain the physiologic levels adequate to support normal organ development and maturation. [ABSTRACT FROM AUTHOR]

: Copyright of Paediatric Respiratory Reviews is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Jacobsson, Bo^1,2,3 (AUTHOR) bo.jacobsson@obgyn.gu.se, Simpson, Joe Leigh⁴ (AUTHOR), Norman, Jane (AUTHOR), Grobman, William (AUTHOR), Bianchi, Ana (AUTHOR), Munjanja, Stephen (AUTHOR), González, Catalina María Valencia (AUTHOR), Mol, Ben W. (AUTHOR), Shennan, Andrew (AUTHOR), FIGO Working Group for Preterm Birth (CORPORATE AUTHOR)

المصدر: International Journal of Gynecology & Obstetrics. Oct2021, Vol. 155 Issue 1, p1-4. 4p.

مصطلحات موضوعية: *CERVICAL cerclage, *PREMATURE labor, *CHILDBIRTH, *PLACENTA praevia, *INFERTILITY, *MULTIPLE pregnancy, *UMBILICAL cord clamping, *BEST practices, *PREMATURE infants

المؤلفون: Uriko, Kristiina, Bartels, Irena

المصدر: Integrative Psychological & Behavioral Science; Jun2023, Vol. 57 Issue 2, p590-606, 17p, 1 Diagram

مصطلحات موضوعية: MATERNAL love, PRENATAL bonding, PREMATURE infants, PSYCHOLOGICAL adaptation, PREMATURE labor, CHILDBIRTH

مستخلص: The objective of this paper is to explore mothers' psychological adaptation related to separation from their newborn children immediately after birth. Mother and child separation has traditionally received attention from the child's perspective, but given that the bond is dyadic, the mother's wellbeing should also be considered. This qualitative study is based on interview data with mothers of premature infants. From the analysis, three themes emerged: concerns during pregnancy about premature birth; emotional strain caused by separation; and the need to protect and to be close to the newborn. Drawing on the perspectives of dialogical self theory and semiotic regulation model, the paper will focus on intra-psychological dynamics and will analyze the adaptation process in terms of I-positions. Based on the analysis, the maternal bond represents the integration of the I-position I-as-mother and My child, which is integrated during the pregnancy into the core of the self. It can be assumed that rupture of the self-continuity is activated by the birth of the child, which is then compounded if the child leaves. The maternal superordinate viewpoint (meta-I-position) directs a woman's behavior and allows for a sense of coherence under dynamic organization related to the birth of the child. The potential for psychological adaptation is presented as an ability to establish self-continuity. [ABSTRACT FROM AUTHOR]

: Copyright of Integrative Psychological & Behavioral Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Fox, Haylee¹ (AUTHOR), Callander, Emily² (AUTHOR) haylee.fox1@my.jcu.edu.au

المصدر: Journal of Paediatrics & Child Health. May2021, Vol. 57 Issue 5, p618-625. 8p.

مصطلحات موضوعية: *PREMATURE labor, *PREMATURE infants, *MOTHERS, *ECONOMIC aspects of diseases, *CHILDBIRTH

مصطلحات جغرافية: AUSTRALIA

مستخلص: Aim: To examine the differences in return to work time after childbirth; the differences in income; and the differences in out of pocket health-care costs between mothers who had a preterm birth and mothers who delivered a full term baby in Australia.Methods: Using administrative data, the length of time and 'risk' of returning to employment for mothers whose child was born premature relative to those whose child was born full term was reported. Multivariate linear regression models were constructed to assess the difference in maternal income and the differences in mean out-of-pocket costs between mothers who had a preterm birth and mothers who had a full term birth.Results: The mean length of time for mothers of babies born full term to return to work was 1.9 years and for mothers of preterm babies it was 2.8 years. Mothers of preterm babies had a significantly lower median income ah at 0-1, 2-3 and 4-5 years postpartum compared to mothers of full term babies. The adjusted mean out of pocket costs for health care paid by mothers who had a preterm birth was $1298 for those whose child was aged 32-36 weeks; and $2491 for those whose child was aged <32 weeks. This is in comparison to mothers of children born 37 weeks and over, whose mean out of pocket costs were $1059.Conclusion: Mothers who have a preterm birth have longer return to work time, a lower weekly income and also have higher out of pocket costs compared with mothers who have a full term birth. [ABSTRACT FROM AUTHOR]

المؤلفون: Kennedy, Eilis¹ (AUTHOR) ekennedy@tavi-port.nhs.uk, O'Nions, Elizabeth¹ (AUTHOR), Wolke, Dieter² (AUTHOR), Johnson, Samantha³ (AUTHOR)

المصدر: Journal of the American Academy of Child & Adolescent Psychiatry. Sep2021, Vol. 60 Issue 9, p1066-1068. 3p.

مصطلحات موضوعية: *PREMATURE labor, *ADOLESCENT psychiatry, *CHILDBIRTH, *CHILD psychiatry, *HIGH-income countries, *RESEARCH, *PREMATURE infants, *RESEARCH methodology, *GESTATIONAL age, *MEDICAL cooperation, *EVALUATION research, *COMPARATIVE studies

مستخلص: Obstetric factors have long been recognized as risk factors for the later development of poor mental health. One of the most consistently reported of these associations is for preterm birth (birth before 37 weeks' gestation), a form of early adversity that impacts health and development across the life course. Preterm birth is not uncommon: in 2014, 10.6% of live births globally (nearly 15 million babies) were preterm.1 Advances in neonatal care since the early 1990s have dramatically increased the numbers of babies who survive extreme preterm birth (birth at <28 weeks' gestation) in high-income countries. This has led to growing interest in how extreme preterm birth impacts longer term outcomes including psychosocial development across the life span. [ABSTRACT FROM AUTHOR]

المؤلفون: Leneuve-Dorilas, Malika¹ (AUTHOR) malika.leneuve@hotmail.fr, Buekens, Pierre² (AUTHOR), Favre, Anne¹ (AUTHOR), Carles, Gabriel³ (AUTHOR), Louis, Alphonse¹ (AUTHOR), Breart, Gerard⁴ (AUTHOR), Nacher, Mathieu¹ (AUTHOR)

المصدر: Journal of Maternal-Fetal & Neonatal Medicine. May2020, Vol. 33 Issue 10, p1709-1716. 8p.

مصطلحات موضوعية: *FIRST trimester of pregnancy, *PREMATURE labor, *CHILDBIRTH, *DEFINITIONS, *PREGNANCY, *PREMATURE infants, *RETROSPECTIVE studies, *ACQUISITION of data, *RECEIVER operating characteristic curves

مصطلحات جغرافية: FRENCH Guiana

مستخلص: Objective: Given the high rate of premature birth in French Guiana (13.5%), and its stability in time, the aim of the present study was to define a predictive score for preterm birth in women with a unique pregnancy in order to help prioritize health resources in the local context.Methods: A retrospective study was conducted on all deliveries of unique pregnancies in French Guiana collected between 1 January 2013 and 31 December 2014 in the Registre d'Issue de Grossesse Informatisé (RIGI), a registry that collects data on live births over 22 weeks of amenorrhea on the territory. Statistically significant predictors (p < .05) of preterm delivery were included in a logistic regression model. The selected variables were chosen to be available during the first trimester. Coefficients were used to establish a score which was categorized and prospectively validated using data from 2015.Results: Seven explanatory variables, all measurable during the first trimester of pregnancy, were significantly associated with preterm birth. The predictive score divided in deciles allowed to establish sensitivity and specificity thresholds. Overall, depending on the chosen threshold the score sensitivity was low and the specificity was high. Lowering the threshold identified half of women as "at risk" for preterm birth.Conclusion: This first trimester score was insufficiently sensitive to identify individual women at risk for preterm delivery. [ABSTRACT FROM AUTHOR]

المؤلفون: Gonçalves, Joana L.¹ joanaglopes@gmail.com, Fuertes, Marina¹, Alves, Maria João¹, Antunes, Sandra², Almeida, Ana Rita³, Casimiro, Rute³, Santos, Margarida^2,4

المصدر: BMC Pregnancy & Childbirth. 5/6/2020, Vol. 20 Issue 1, p1-16. 16p.

مصطلحات موضوعية: *PREMATURE labor, *PREMATURE infants, *MOTHER-infant relationship, *MATERNAL health services, *CHILDBIRTH, *POSTPARTUM depression, *PREGNANCY, *NEONATAL intensive care, *PSYCHOLOGY of mothers, *GESTATIONAL age, *NEONATAL intensive care units, *RESEARCH funding, *LABOR (Obstetrics), *MOTHER-child relationship

مستخلص: Background: Mothers' reports about pregnancy, maternity and their experiences during the perinatal period have been associated with infants' later quality of attachment and development. Yet, there has been little research with mothers of very preterm newborns. This study aimed to explore mothers' experiences related to pregnancy, premature birth, relationship with the newborn, and future perspectives, and to compare them in the context of distinct infants' at-birth-risk conditions.Methods: A semi-structured interview was conducted with women after birth, within the first 72 h of the newborn's life. A total of 150 women participated and were divided in three groups: (1) 50 mothers of full-term newborns (Gestational Age (GA) ≥ 37 weeks; FT), (2) 50 mothers of preterm newborns (GA 32-36 weeks; PT) and (3) 50 mothers of very preterm newborns (GA < 32 weeks; VPT).Results: Mothers of full-term infants responded more often that their children were calm and that they did not expect difficulties in taking care of and providing for the baby. Mothers of preterm newborns although having planned and accepted well the pregnancy (with no mixed or ambivalent feelings about it) and while being optimistic about their competence to take care of the baby, mentioned feeling frightened because of the unexpected occurrence of a premature birth and its associated risks. Mothers of very preterm newborns reported more negative and distressful feelings while showing more difficulties in anticipating the experience of caring for their babies.Conclusion: The results indicate that Health Care Systems and Neonatal Care Policy should provide differentiated psychological support and responses to mothers, babies and families, taking into account the newborns' GA and neonatal risk factors. [ABSTRACT FROM AUTHOR]

المؤلفون: Pradhan, Dinesh¹ (AUTHOR) dinesh.bhutan@gmail.com, Nishizawa, Yoriko¹ (AUTHOR), Chhetri, Hari P² (AUTHOR)

المصدر: Journal of Tropical Pediatrics. Apr2020, Vol. 66 Issue 2, p163-170. 8p.

مصطلحات موضوعية: *PREMATURE labor, *PREMATURE infants, *NEONATAL mortality, *CHILDBIRTH, *BIRTH rate, *PUBLIC hospitals, *CESAREAN section, *RESEARCH, *NEONATAL intensive care, *NEONATAL diseases, *RESEARCH methodology, *NEONATAL intensive care units, *FETAL growth retardation, *DISEASES, *EVALUATION research, *MEDICAL cooperation, *COMPARATIVE studies, *PREGNANCY complications, *MEDICAL referrals, *DISEASE prevalence, *INFANT mortality, *SMALL for gestational age

مصطلحات جغرافية: BHUTAN

مستخلص: Introduction: Preterm birth-related complications are the leading cause of under-5 mortality globally. Bhutan does not have a reliable preterm birth rate or data regarding outcome of preterm babies.Aim: To determine the preterm birth rate at the Jigme Dorji Wangchuck National Referral Hospital (JDWNRH) in Thimphu, Bhutan, and assess their outcomes.Methods: All live preterm births at JDWNRH from 1 January 2017 to 31 December 2017 were followed from birth till hospital discharge. Maternal demographic data, pregnancy details and delivery details were collected. Morbidity and mortality information as well as discharge outcome were collected on babies admitted to neonatal intensive care unit (NICU).Results: Preterm birth rate among live births was 6.4%. Most mothers were younger than 30 years, housewives and had secondary education. Pregnancy registration rate and adequacy of antenatal visits were high. Most preterm births were singleton and the predominant mode of delivery was cesarean section. More than half of the births were initiated spontaneously, and the male:female ratio was 1.2:1. Most babies were late preterm and low birth weight. Half of them required NICU admission. Overall mortality rate was 11% and 21.6% for admitted preterm neonates. Preterm small-for-gestational-age neonates, and those born after provider-initiated preterm birth had significantly increased risk of mortality. Most preterm neonates were discharged without complications. The rate of extrauterine growth restriction was high.Conclusion: This is the first study on the prevalence of preterm births and their outcomes in the largest tertiary-care hospital in Bhutan. [ABSTRACT FROM AUTHOR]