المؤلفون: Spaegele, Nina¹ (AUTHOR), Ditzer, Julia^1,2 (AUTHOR) julia.ditzer@gmail.com, Rodrigues, Mariana¹ (AUTHOR), Talmon, Anat^1,3 (AUTHOR) atalmon@mail.huji.ac.il

المصدر: BMC Pregnancy & Childbirth. 2/5/2024, Vol. 24 Issue 1, p1-10. 10p.

مصطلحات موضوعية: *PREMATURE labor, *SOMATIC sensation, *SELF-presentation, *PREGNANT women, *DOULAS, *INFANT mortality

مستخلص: Background: Preterm birth, which occurs when a baby is born before 37 weeks, has enormous implications for public health. It is the leading cause of infant death and mortality in children under the age of five. Unfortunately, the multifaceted causes of preterm birth are not fully understood. One construct that has received increasing attention in women's transition to motherhood is body boundaries, i.e., the metaphorical barriers that separate the self from the outer, surrounding "not self." This study aims to examine the role of well-defined and disturbed body boundaries in predicting preterm birth. Methods: A sample of 655 Israeli pregnant women reported their sense of body boundaries (BBS, as measured by the Sense of Body Boundaries Survey) pre- and postnatally. We performed a General Linear Model (GLM) testing the effect of the BBS total score on the days women delivered before their due date and controlling for whether it was the women's first child. Results: Our GLMs controlling for whether it was the women's first child showed that the BBS total mean exhibited a significant predictive effect on the number of days delivered before the due date (F(57,313) = 3.65, p <.001). Conclusions: These results demonstrate heterogeneity in women's sense of body boundaries during pregnancy and are the first to disentangle a link between disturbed body boundaries and preterm birth. Mediating mechanisms in this relation, e.g., psychosocial stress, as well as clinical implications are discussed in detail. [ABSTRACT FROM AUTHOR]

المؤلفون: Ribeiro, Reitan¹ (AUTHOR) reitanribeiro@hotmail.com, Anselmi, Maria Cristina² (AUTHOR), Schneider, Gunther Alex³ (AUTHOR), Rodrigues Furtado, José Pio⁴ (AUTHOR), Mohamed Abau Shwareb, Mohamed Gaber³ (AUTHOR), Linhares, José Clemente¹ (AUTHOR)

المصدر: Fertility & Sterility. Jul2023, Vol. 120 Issue 1, p188-193. 6p.

مصطلحات موضوعية: *PREMATURE labor, *CHILDBIRTH, *CESAREAN section, *CANCER hospitals, *APGAR score, *LIPOSARCOMA

الملخص (بالإنجليزية): To our knowledge, to report the first case of live birth of a child after uterine transposition (UT), pelvic radiotherapy, and subsequent uterine repositioning. Case report. Tertiary referral cancer hospital. A 28-year-old nulligravid woman with left iliac and thoracic synchronous myxoid low-grade liposarcoma, which was resected with close margins. The patient underwent UT before undergoing pelvic (60 Gy) and thoracic (60 Gy) radiation on October 25, 2018. After radiotherapy, her uterus was reimplanted in the pelvis on February 20, 2019. The patient became pregnant in June 2021 and experienced an uneventful pregnancy until 36 weeks, when the patient started preterm labor and had a cesarean section delivery on January 26, 2022. A boy was delivered after a gestation period of 36 weeks and 2 days (2686 g and 46.5 cm), with Apgar scores of 5 and 9, respectively; both mother and child were discharged the following day. After 1 year of follow-ups, the infant maintained normal development and the patient showed no signs of recurrence. To our knowledge, this case of the first live birth after UT is a proof-of-concept for the viability of UT as a procedure to prevent infertility in patients requiring pelvic radiotherapy. [ABSTRACT FROM AUTHOR]

Abstract (Spanish): Primer nacido vivo tras transposición uterina Hasta donde sabemos, reportar el primer caso de nacido vivo de un niño tras transposición uterina (UT), radioterapia pélvica y posterior reposicionamiento uterino. Caso de estudio. Hospital oncológico terciario de referencia. Mujer de 28 años nuligesta, con liposarcoma mixoide de bajo grado sincrónico torácico e ilíaco izquierdo, que fue extirpado con márgenes estrechos. La paciente fue sometida a UT antes de recibir radioterapia pélvica (60Gy) y torácica (60Gy) el 25 de octubre de 2018. Tras la radioterapia, su útero fue reimplantado en la pelvis el 20 de febrero de 2019. La paciente resultó embarazada en junio de 2021 y experimentó una gestación sin incidentes hasta las 36 semanas, cuando la paciente inició trabajo de parto prematuro y tuvo un parto por cesárea el 26 de enero de 2022. Un niño nació tras de un período de gestación de 36 semanas y 2 días (2686 g y 46,5 cm), con puntuaciones de Apgar de 5 y 9, respectivamente; tanto la madre como el niño fueron dados de alta al día siguiente. Después de 1 año de seguimiento, el bebé mantuvo un desarrollo normal y la paciente no mostró signos de recurrencia. Para nuestro conocimiento. Este primer caso de recién nacido vivo tras UT es una prueba de concepto para la viabilidad del UTcomo procedimiento para prevenir la infertilidad en pacientes que requieran radioterapia pélvica. [ABSTRACT FROM AUTHOR]

المؤلفون: Adamczak, Ada Maria, Werblińska, Alicja, Jamka, Małgorzata, Walkowiak, Jarosław

المصدر: Biomedicines; Mar2024, Vol. 12 Issue 3, p490, 19p

مصطلحات موضوعية: GUT microbiome, PREMATURE labor, HUMAN microbiota, CHILDREN'S health

مستخلص: In recent years, the number of scientific publications on the role of intestinal microbiota in shaping human health, as well as the occurrence of intestinal dysbiosis in various disease entities, has increased dynamically. However, there is a gap in comprehensively understanding the factors influencing a child's gut microbiota. This review discusses the establishment of gut microbiota and the immunological mechanisms regulating children's microbiota, emphasising the importance of prioritising the development of appropriate gut microbiota in a child from the planning stages of pregnancy. The databases PubMed, Web of Sciences, Cochrane, Scopus and Google Scholar were searched to identify relevant articles. A child's gut microbiota composition is influenced by numerous factors, such as diet during pregnancy, antibiotic therapy, the mother's vaginal microbiota, delivery method, and, later, feeding method and environmental factors. During pregnancy, the foetus naturally acquires bacterial strains from the mother through the placenta, thereby shaping the newborn's immune system. Inappropriate maternal vaginal microbiota may increase the risk of preterm birth. Formula-fed infants typically exhibit a more diverse microbiota than their breastfed counterparts. These factors, among others, shape the maturation of the child's immune system, impacting the production of IgA antibodies that are central to cellular humoral immune defence. Further research should focus on identifying specific microbiota–immune system interactions influencing a child's immune health and developing personalised treatment strategies for immune-related disorders. [ABSTRACT FROM AUTHOR]

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المؤلفون: Khayargoli, Pranamika, Mayrand, Marie-Hélène, Niyibizi, Joseph, Audibert, François, Laporte, Louise, Lacaille, Julie, Carceller, Ana Maria, Lacroix, Jacques, Comète, Émilie, Coutlée, François, Trottier, Helen

المصدر: Viruses (1999-4915); Feb2024, Vol. 16 Issue 2, p298, 13p

مصطلحات موضوعية: HUMAN papillomavirus, VIRAL load, PREGNANCY, PREMATURE labor, FIRST trimester of pregnancy, THIRD trimester of pregnancy, CHILDBIRTH

مستخلص: Recent evidence shows increased preterm birth risk with human papillomavirus-16 (HPV16) infection during pregnancy. This study aimed to measure the association between HPV16 viral load during pregnancy and preterm birth. We used data from participants in the HERITAGE study. The Linear Array assay was used for HPV DNA testing on vaginal samples collected during the first and third trimesters of pregnancy. The HPV16 viral load was measured with a real-time polymerase chain reaction. We used logistic regression to measure the associations between HPV16 viral load during pregnancy and preterm birth (defined as birth before 37 weeks of gestation). The adjusted odd ratios (aORs) and the 95% confidence intervals [CIs] were estimated with inverse probability treatment weighting of the propensity score. This study included 48 participants who tested positive for HPV16 during the first trimester of pregnancy. The aOR for the association between first-trimester HPV16 viral load (higher viral load categorized with a cutoff of 0.5 copy/cell) was 13.04 [95% CI: 1.58–107.57]). Similar associations were found using different cutoffs for the categorization of viral load during the first and third trimesters. Our findings suggest a strong association between a high HPV16 viral load during pregnancy and preterm birth, demonstrating a biological gradient that reinforces the biological plausibility of a causal association. [ABSTRACT FROM AUTHOR]

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المؤلفون: Gebreslasie, Kahsay Zenebe, Weldemariam, Solomon, Gebre, Gelawdyos, Zenebe, Dawit, Mehari, Mihreteab, Birhane, Aklil, Dewey, Rebecca Susan

المصدر: Scientific Reports; 1/16/2024, Vol. 14 Issue 1, p1-7, 7p

مصطلحات موضوعية: INTIMATE partner violence, LOW birth weight, BIRTH weight, PREGNANCY, PREMATURE labor, CHILDBIRTH, PREGNANT women

مصطلحات جغرافية: TIGRAY Kifle Hager (Ethiopia), ETHIOPIA

مستخلص: Intimate partner Violence (IPV) can affect any woman, irrespective of their economic status, religion, or culture. This is a human-rights issue and due to its prevalence and adverse effects on pregnancy and birth, it must be given greater attention. Further, there is a lack of data in the Tigray region about adverse birth outcomes due to intimate partner violence during pregnancy. The aim of this study was to assess intimate partner violence during pregnancy and its association with low birth weight and preterm birth in Tigray region. Across-sectional study design was used. 647 women were involved in the study. Simple random sampling techniques were employed to select health facilities and systematic sampling was used to select study participants. Data were entered using Epi info version 3.5.1 and was analyzed using SPSSversion 20. Logistic regression analysis was conducted to assess the association between exposure to intimate partner violence during pregnancy and preterm birth and low birth weight while adjusting for possible confounders. The prevalence of intimate partner violence during pregnancy was 7.3% and the prevalence of low birth weight and preterm birth were 18.5% and 10.8% respectively. There was a statistically significant association between exposure to intimate partner violence during pregnancy and low birth weight. After adjustment for socioeconomic status, women's habits and obstetric factors, the pregnant women who were exposed to intimate partner violence during pregnancy were two times more likely to have a child with a low birth weight (2.39 (95% CI: 1.26–4.55)). The prevalence of intimate partner violence during pregnancy, low birth weight, and preterm birth in this study was high. Women who experienced intimate partner violence during pregnancy had an increased risk of low birth weight. These findings justify a call to the federal minster of health to take measures aimed at avoiding intimate partner violence during pregnancy to reduce adverse birth outcomes. [ABSTRACT FROM AUTHOR]

: Copyright of Scientific Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Ünal, Canan, Tanaçan, Atakan, Fadiloğlu, Erdem, Çağan, Murat, Yücesoy, Halise Meltem, Beksaç, Mehmet Sinan

المصدر: Journal of the Turkish-German Gynecological Association; Dec2023, Vol. 24 Issue 4, p241-245, 5p

مصطلحات موضوعية: OBSTRUCTIVE lung disease diagnosis, ECHOCARDIOGRAPHY, CHILDBIRTH, STATURE, LENGTH of stay in hospitals, PNEUMONIA, ACADEMIC medical centers, BODY weight, PERICARDIAL effusion, PREGNANT women, RETROSPECTIVE studies, MANN Whitney U Test, GESTATIONAL age, PREGNANCY outcomes, VITAL capacity (Respiration), PREECLAMPSIA, RISK assessment, SCOLIOSIS, SYMPTOMS, PULMONARY function tests, DESCRIPTIVE statistics, CHI-squared test, BIRTH weight, FORCED expiratory volume, HOSPITAL care, PUERPERIUM, DATA analysis software, CESAREAN section, LONGITUDINAL method, PREMATURE labor

مصطلحات جغرافية: TURKEY

مستخلص: Objective: To demonstrate the impact of scoliosis on pregnancy and gestational outcome. Material and Methods: We retrospectively evaluated gestational outcomes of pregnant women with scoliosis at Hacettepe University Hospital between 2008 and 2018. Cases were grouped according to the presence of previous scoliosis surgery and compared in terms of gestational week at birth, birthweight, rate of neonatal intensive care unit admission, hospitalization during pregnancy, route of delivery, type of anesthesia at labor and postpartum intensive care unit admission rate. Ejection fraction (EF), functional vital capacity (FVC), forced expiratory volume (FEV1) and FEV1/FVC ratio values were also recorded. Results: A total of 23 women were included, of whom 12 (52.2%) had a prior scoliosis surgery. One of the 23 (4.3%) cases was terminated due to respiratory problems, while the remaining 22 cases resulted in deliveries. The median gestational week at birth was 38.2 and the median birth weight was 3150 g. Median (range) maternal height was 143 (80-160) cm while median (range) maternal weight was 51 (35-86) kg. Three (13.6%) were diagnosed with restrictive lung disease. No significant difference was found between operated and non-operated groups in terms of respiratory function test results, cardiac EF and other related demographic and clinical features. Overall cesarean delivery rate was 63.6% (14/22) and cesarean section rate was significantly higher in the operated group (83.3% versus 40%) (p=0.04). Conclusion: Cesarean section rate was increased in this cohort of pregnancies in women with scoliosis and who had previous scoliosis surgery. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of the Turkish-German Gynecological Association is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Baas, Melanie A. M., Stramrood, Claire A. I., Dijksman, Lea M., Vanhommerig, Joost W., de Jongh, Ad, van Pampus, Mariëlle G.

المصدر: Acta Obstetricia et Gynecologica Scandinavica; Nov2023, Vol. 102 Issue 11, p1575-1585, 11p

مصطلحات موضوعية: EMDR (Eye-movement desensitization & reprocessing), FEAR of childbirth, PREGNANT women, INDUCED labor (Obstetrics), RANDOMIZED controlled trials, PREMATURE labor

مصطلحات جغرافية: NETHERLANDS

مستخلص: Introduction: Pregnant women with fear of childbirth display an elevated risk of a negative delivery experience, birth‐related post‐traumatic stress disorder, and adverse perinatal outcomes such as preterm birth, low birthweight, and postpartum depression. One of the therapies used to treat fear of childbirth is eye movement desensitization and reprocessing (EMDR) therapy. The purpose of the present study was to determine the obstetric safety and effectiveness of EMDR therapy applied to pregnant women with fear of childbirth. Material and methods: A randomized controlled trial (the OptiMUM‐study) was conducted in two teaching hospitals and five community midwifery practices in the Netherlands (www.trialregister.nl, NTR5122). Pregnant women (n = 141) with a gestational age between 8 and 20 weeks and suffering from fear of childbirth (i.e. sum score on the Wijma Delivery Expectations Questionnaire ≥85) were randomly allocated to either EMDR therapy (n = 70) or care‐as‐usual (CAU) (n = 71). Outcomes were maternal and neonatal outcomes and patient satisfaction with pregnancy and childbirth. Results: A high percentage of cesarean sections (37.2%) were performed, which did not differ between groups. However, women in the EMDR therapy group proved seven times less likely to request an induction of labor without medical indication than women in the CAU group. There were no other significant differences between the groups in maternal or neonatal outcomes, satisfaction, or childbirth experience. Conclusions: EMDR therapy during pregnancy does not adversely affect pregnancy or the fetus. Therefore, therapists should not be reluctant to treat pregnant women with fear of childbirth using EMDR therapy. [ABSTRACT FROM AUTHOR]

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المؤلفون: Lišková, Kateřina, Jarska, Natalia, Gagyiova, Annina, Aguilar López-Barajas, José Luis, Rábová, Šárka Caitlín

المصدر: Medical History; Oct2023, Vol. 67 Issue 4, p285-306, 22p

مصطلحات موضوعية: PREMATURE labor, MARRIAGE, PREGNANCY, PSYCHOLOGICAL factors, REPRODUCTIVE health

مصطلحات جغرافية: CZECHOSLOVAKIA, GERMANY (East)

مستخلص: Reproductive health in state socialism is usually viewed as an area in which the broader contexts of women's lives were disregarded. Focusing on expert efforts to reduce premature births, we show that the social aspects of women's lives received the most attention. In contrast to typical descriptions emphasising technological medicalisation and pharmaceuticalisation, we show that expertise in early socialism was concerned with socio-medical causes of prematurity, particularly work and marriage. The interest in physical work in the 1950s evolved towards a focus on psychological factors in the 1960s and on broader socio-economic conditions in the 1970s. Experts highlighted marital happiness as conducive to healthy birth and considered unwed women more prone to prematurity. By the 1980s, social factors had faded from interest in favour of a bio-medicalised view. Our findings are based on a rigorous comparative analysis of medical journals from Hungary, Poland, Czechoslovakia and East Germany. [ABSTRACT FROM AUTHOR]

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المؤلفون: Yim, Gyeyoon^1,2 (AUTHOR), Roberts, Andrea² (AUTHOR), Wypij, David^3,4,5 (AUTHOR), Kioumourtzoglou, Marianthi-Anna⁶ (AUTHOR), Weisskopf, Marc G^1,2 (AUTHOR) mweissko@hsph.harvard.edu

المصدر: International Journal of Epidemiology. Dec2021, Vol. 50 Issue 6, p1886-1896. 11p.

مصطلحات موضوعية: *LOW birth weight, *PREMATURE labor, *CHILDBIRTH, *PREGNANCY complications, *PREGNANCY

مستخلص: Background: Diethylstilbestrol (DES) is an endocrine-disrupting pharmaceutical prescribed to pregnant women to prevent pregnancy complications between the 1940s and 1970s. Although DES has been shown in animal studies to have multigenerational effects, only two studies have investigated potential multigenerational effects in humans on preterm birth (PTB), and none on low birthweight (LBW)-major determinants of later life health.Methods: Nurses' Health Study (NHS) II participants (G1; born 1946-64) reported their mothers' (G0) use of DES while pregnant with them. We used cluster-weighted generalized estimating equations to estimate odds ratios (OR) and 95% confidence intervals (CI) for risk of LBW and PTB among the grandchildren by grandmother use of DES. G1 birthweight and gestational age were considered to explore confounding by indication.Results: Among 54 334 G0-G1/grandmother-mother pairs, 973 (1.8%) G0 used DES during pregnancy with G1. Of the 128 275 G2 children, 4369 (3.4%) were LBW and 7976 (6.2%) premature. Grandmother (G0) use of DES during pregnancy was associated with an increased risk of G2 LBW [adjusted OR (aOR) = 3.09; 95% CI: 2.57, 3.72], that was reduced when restricted to term births (aOR = 1.59; 95% CI: 1.08, 2.36). The aOR for PTB was 2.88 (95% CI: 2.46, 3.37). Results were essentially unchanged when G1 birthweight and gestational age were included in the model, as well as after adjusting for other potential intermediate variables, such as G2 pregnancy-related factors.Conclusions: Grandmother use of DES during pregnancy is associated with an increased risk of LBW, predominantly through an increased risk of PTB. Results when considering G1 birth outcomes suggest this does not result from confounding by indication. [ABSTRACT FROM AUTHOR]

المؤلفون: Martinez-Perez, Oscar¹ Oscarmartinezgine@gmail.com, Prats Rodriguez, Pilar², Muner Hernandez, Marta³, Encinas Pardilla, Maria Begoña¹, Perez Perez, Noelia⁴, Vila Hernandez, Maria Rosa⁵, Villalba Yarza, Ana⁶, Nieto Velasco, Olga⁷, Del Barrio Fernandez, Pablo Guillermo⁸, Forcen Acebal, Laura⁹, Orizales Lago, Carmen Maria¹⁰, Martinez Varea, Alicia¹¹, Muñoz Abellana, Begoña¹², Suarez Arana, Maria¹³, Fuentes Ricoy, Laura¹⁴, Martinez Diago, Clara¹⁵, Janeiro Freire, Maria Jesus¹⁶, Alférez Alvarez-Mallo, Macarena¹⁷, Casanova Pedraz, Cristina¹⁸, Alomar Mateu, Onofre¹⁹

المصدر: BMC Pregnancy & Childbirth. 4/1/2021, Vol. 21 Issue 1, p1-11. 11p.

مصطلحات موضوعية: *COVID-19 pandemic, *PREMATURE labor, *DELIVERY (Obstetrics), *CHILDBIRTH, *PREGNANCY complications

مستخلص: Background: To determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, the cause of COVID-19 disease) exposure in pregnancy, compared to non-exposure, is associated with infection-related obstetric morbidity.Methods: We conducted a multicentre prospective study in pregnancy based on a universal antenatal screening program for SARS-CoV-2 infection. Throughout Spain 45 hospitals tested all women at admission on delivery ward using polymerase-chain-reaction (PCR) for COVID-19 since late March 2020. The cohort of positive mothers and the concurrent sample of negative mothers was followed up until 6-weeks post-partum. Multivariable logistic regression analysis, adjusting for known confounding variables, determined the adjusted odds ratio (aOR) with 95% confidence intervals (95% CI) of the association of SARS-CoV-2 infection and obstetric outcomes.Main Outcome Measures: Preterm delivery (primary), premature rupture of membranes and neonatal intensive care unit admissions.Results: Among 1009 screened pregnancies, 246 were SARS-CoV-2 positive. Compared to negative mothers (763 cases), SARS-CoV-2 infection increased the odds of preterm birth (34 vs 51, 13.8% vs 6.7%, aOR 2.12, 95% CI 1.32-3.36, p = 0.002); iatrogenic preterm delivery was more frequent in infected women (4.9% vs 1.3%, p = 0.001), while the occurrence of spontaneous preterm deliveries was statistically similar (6.1% vs 4.7%). An increased risk of premature rupture of membranes at term (39 vs 75, 15.8% vs 9.8%, aOR 1.70, 95% CI 1.11-2.57, p = 0.013) and neonatal intensive care unit admissions (23 vs 18, 9.3% vs 2.4%, aOR 4.62, 95% CI 2.43-8.94, p <  0.001) was also observed in positive mothers.Conclusion: This prospective multicentre study demonstrated that pregnant women infected with SARS-CoV-2 have more infection-related obstetric morbidity. This hypothesis merits evaluation of a causal association in further research. [ABSTRACT FROM AUTHOR]