المؤلفون: Mbayo, Fiston Ilunga^1,2 ilungambayofiston@gmail.com, Nsenga, Yannick Bienge^1,2, Lupitshi, Gloire Kasongo^1,2, Nyemba, Kennedy Twite^1,2, Mpingisha, Cédrick Mwamba^1,2, Kambala, Justin Batambe^1,2, Muzinga, Gaetan Kabongo^1,2

المصدر: Pan African Medical Journal. Sep-Dec2020, Vol. 37, p1-7. 7p.

مصطلحات موضوعية: *PREMATURE labor, *URINARY tract infections, *MATERNAL age, *CHILDBIRTH, *OBSTETRICS

مستخلص: Premature birth remains a major concern for obstetric and pediatric teams. The objective of our work is to determine the causes and frequencies of premature childbirth in our environment, more particularly at the HGR Malemba. This is a descriptive cross-sectional study conducted in the obstetrics and gynecology department of the HGR Malemba. Who included 24 premature deliveries between 1st January and 31st December 2018. The hospital frequency of preterm birth was 4.6%, the average age of childbirth was 28 ± 6.7 years, married births were 75%, housewives were 45.8%, the women born were large multiparous in 41.7%, the pathologies occurring during pregnancy: urinary tract infections (75%); malaria (25%), maternal age <18 years or >35 years and urinary tract infections constitute important risk factors for preterm birth. The study we conducted shows that the rate of premature delivery remains high in the city of Malemba. The early identification of the cause allows their reduction through the improvement of the health care system in our environment. [ABSTRACT FROM AUTHOR]

المؤلفون: Mosbah, Alaa¹ (AUTHOR) alaamosbah@hotmail.com, Barakat, Rafik¹ (AUTHOR), Nabiel, Yasmin² (AUTHOR), Barakat, Ghada² (AUTHOR)

المصدر: Journal of Maternal-Fetal & Neonatal Medicine. Mar2018, Vol. 31 Issue 6, p720-725. 6p.

مصطلحات موضوعية: *PAPILLOMAVIRUSES, *PREMATURE labor, *OBSTETRICS, *MEDICINE, *CHILDBIRTH, *PREMATURE labor prevention, *PAPILLOMAVIRUS disease diagnosis, *GENE expression, *GESTATIONAL age, *PAPILLOMAVIRUS diseases, *POLYMERASE chain reaction, *PROTEOLYTIC enzymes, *SPECIALTY hospitals, *CASE-control method

مصطلحات جغرافية: EGYPT

مستخلص: Introduction: This study aimed to detect the correlation between human papillomavirus (HPV) and spontaneous preterm labor in Egyptian women and its association to the human papilloma viral load and MPP2 gene expression.Material and Methods: We performed an observational comparative case-control study in Department of Obstetric and Gynecology, Mansoura University Hospitals over women presented with spontaneous preterm labor, besides females admitted for giving birth at full term to detect conserved sequence in HPV-L1 gene (GP5/GP6) followed by genotype detection of high- and low-risk HPVs with quantification of the viral load and the MMP2 gene expression using real-time polymerase chain reaction (PCR).Results: The prevalence of HPV was 18.1% in preterm females, but only 4% in full-term women (p value = 0.019*). Twenty percent were PCR positive for HPV 16 and 40% for HPV 18 whereas none of the control was positive for any of the studied high-risk genotypes. Thirty percent were PCR positive for HPV 6 and 10% were positive for HPV 11. MMP2 gene expression was significantly higher in preterm than full term. Human papilloma viral load was found to be positively correlated to the rate of MMP2 expression and the gestational age was significantly related to the viral load and the rate of expression of MMP2 gene.Conclusion: Human pabilloma virus especially high-risk genotypes was correlated to spontaneous preterm labor in Egyptian females through increasing early expression of MMP2 gene. The time of occurrence of preterm labor was affected by the viral load and so the rate of expression of MMP2 gene. [ABSTRACT FROM AUTHOR]

المؤلفون: Mascarenhas, Mariano¹, Sunkara, Sesh Kamal², Antonisamy, Belavendra³, Kamath, Mohan S.⁴ dockamz@gmail.com

المصدر: European Journal of Obstetrics & Gynecology & Reproductive Biology. Nov2017, p60-67. 8p.

مصطلحات موضوعية: *PREMATURE labor, *LOW birth weight, *OVUM donation, *CELLS, *CHILDBIRTH, *OBSTETRICS, *REPRODUCTION, *FERTILIZATION in vitro, *PREMATURE infants, *EVALUATION of medical care, *META-analysis, *PREGNANCY, *SYSTEMATIC reviews

مستخلص: Objectives: To perform a systematic review and meta-analysis of the known literature to assess whether the perinatal outcomes are different after oocyte donation (OD) compared to autologous oocyte (AO) in vitro fertilization (IVF) pregnancies.Study Design: A systematic literature search was done for studies published in English from 1980 to 2016. Studies comparing perinatal outcomes of pregnancies following fresh or frozen OD and AO IVF were included. Meta-analysis was performed using the Rev Man 5.3 software (Cochrane Collaboration) for the perinatal outcomes of PTB (<37 weeks), early PTB (<32 weeks), LBW (<2500g), very LBW (<1500g), and SGA (<10th centile). Six studies provided data on PTB, three studies on early PTB, five studies on LBW, four studies on very LBW and three studies on SGA after fresh embryo transfer. Two studies provided data on PTB, early PTB, LBW and very LBW after frozen embryo transfer.Results: There is an increased risk of PTB following fresh embryo transfer in OD pregnancies than in AO IVF pregnancies (OR 1.45, 95% CI 1.20-1.77). If the PTB risk is assumed to be to 9% for pregnancies following AO IVF, then OD pregnancies will have a PTB risk between 10.8% and 15.9%. Similarly, the risk of LBW is higher after fresh embryo transfer in OD pregnancies than AO IVF pregnancies (OR 1.34, 95% CI 1.12-1.60). If the assumed LBW risk is 9% for AO IVF pregnancies, then OD pregnancies have a LBW risk between 10.1% and 14.4%. There is an increased risk of early PTB (OR 2.14, 95% CI 1.40-3.25) and very LBW (OR 1.51, 95% CI 1.17-1.95) in a fresh embryo transfer after OD as compared to AO IVF pregnancies.Conclusions: There appears to be a higher risk of adverse perinatal outcomes following fresh OD compared to AO IVF pregnancies. [ABSTRACT FROM AUTHOR]

المصدر: Women's Health Weekly; 2024, p1179-1179, 1p

مصطلحات موضوعية: PREMATURE infants, PREMATURE labor, RESEARCH personnel, CHILDBIRTH, BLOOD proteins, FETAL physiology, CARRIER proteins

الشركة/الكيان: TECHNISCHE Universiteit Eindhoven

مستخلص: A recent report from researchers at Eindhoven University of Technology discusses the development of an extrauterine environment for extremely premature infants, known as Artificial Placenta and Artificial Womb (APAW) technology. This technology aims to provide an optimal environment for newborn development by allowing further lung maturation and delaying gas exposure to oxygen. The report analyzes relevant fetal physiology literature, provides insights from APAW studies, and identifies considerations for the obstetric procedure of transferring an infant from the native uterus to an APAW system. The researchers also provide suggestions to improve sterility, fetal and maternal well-being, and the prevention of neonatal transition. [Extracted from the article]

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المصدر: Women's Health Weekly; 2024, p965-965, 1p

مصطلحات موضوعية: LOW birth weight, PRENATAL care, RESEARCH personnel, CHILDBIRTH, LIFE sciences, PREMATURE labor

مستخلص: A recent study conducted by researchers from the University of Indonesia examined the association between antenatal care (ANC) utilization and low birth weight (LBW) children among women with high-risk births. The study utilized data from the 2017 Indonesia Demographic and Health Survey and found that adequate ANC utilization was significantly associated with LBW among women with more than two children. Preterm birth was also found to be more likely to result in LBW. The researchers concluded that there is a need for increased monitoring of pregnant women with high-risk births and for improved implementation of qualified ANC standards. [Extracted from the article]

: Copyright of Women's Health Weekly is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Klerman, Lorraine V.¹, Cliver, Suzanne P.², Goldenberg, Robert L.²

المصدر: American Journal of Public Health. Aug1998, Vol. 88 Issue 8, p1182-1185. 4p. 4 Charts.

مصطلحات موضوعية: PREGNANCY, PREMATURE labor, PRENATAL care, CHILDBIRTH, OBSTETRICS, AFRICAN Americans

مستخلص: Objectives. The objective of this study was to determine whether the length of the interval between pregnancies was associated with either preterm birth or intrauterine growth retardation in a low-income, largely Black population. Methods. The study population consisted of 4400 women who had received prenatal care in county clinics and had two consecutive singleton births between 1980 and 1990. Results. Interpregnancy intervals were positively associated with age and negatively associated with the trimester in which care was initiated in the second pregnancy. Whites had shorter intervals than non-Whites. The percentage of preterm births increased as the length of the interpregnancy interval decreased, but only for women who had not had a previous preterm birth. The association between interval and preterm birth was maintained when other factors associated with preterm birth were controlled. There was no significant relationship between intrauterine growth retardation and interpregnancy interval. Conclusions. Women, particularly those who are poor and young, should be advised of the potential harm to their infants of short interpregnancy intervals. [ABSTRACT FROM AUTHOR]

: Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Papanna, R.¹, Mann, L. K.¹, Baschat, A. A.², Bebbington, M. W.¹, Khalek, N.³, Johnson, A.¹, Snowise, S.¹, Moise, K. J.¹

المصدر: Ultrasound in Obstetrics & Gynecology. Feb2015, Vol. 45 Issue 2, p175-182. 8p.

مصطلحات موضوعية: *PREMATURE labor, *DELIVERY (Obstetrics), *CHILDBIRTH, *OBSTETRICS, *LABOR (Obstetrics), *LASER surgery

مستخلص: ABSTRACT Objectives To determine the risk factors for spontaneous preterm delivery ( PTD) or preterm prelabor rupture of membranes ( PPROM) at < 34 weeks' gestation after fetoscopic laser surgery for twin-twin transfusion syndrome and to identify the optimal threshold for preoperative cervical length ( CL) that indicates a high risk for spontaneous PTD. Methods This was a secondary analysis of data prospectively collected from 449 patients at three fetal centers. CL measurements were obtained by preoperative transvaginal ultrasound, at a gestational age of 16-26 weeks. The risk factors associated with spontaneous PTD before 34 weeks' gestation were determined using multivariable logistic regression analysis. We excluded patients with dual fetal demise and those with maternal or fetal indications for delivery without PPROM ( n = 63). The optimal threshold for cervical length to predict spontaneous PTD before 34 weeks was determined using a receiver-operating characteristics ( ROC) curve and Youden index. Additionally, the CL threshold for spontaneous PTD at 2-week intervals between 24 and 34 weeks was determined. Results Spontaneous PTD before 34 weeks occurred in 206 (53.4%) of the included patients. Only the preoperative CL was significantly associated with spontaneous PTD. The preoperative CL was normally distributed with a mean of 37.6 ± 10.3 mm (range, 5-66 mm). Maternal age and parity were positively associated, and gestational age at procedure and anterior placenta were negatively associated, with CL on multivariable linear regression analysis. The area under the ROC curve for predicting spontaneous PTD with CL measurements was 0.61 ( P = 0.02) and the optimal threshold was 28 mm with a Youden index of 0.19 (sensitivity and specificity of 92% and 27%, respectively). A CL measurement of < 28 mm increased the risk of spontaneous PTD for all gestational age thresholds. Conclusions Spontaneous PTD at < 34 weeks' gestation is associated with a preoperative CL of < 28 mm. Preventive strategies should focus on this high-risk group. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd. [ABSTRACT FROM AUTHOR]

المؤلفون: Mezwa, Kathryn, Adelsheim, Lee, Markenson, Glenn

المصدر: Seminars in Reproductive Medicine; 2019, Vol. 37 Issue 5/6, p215-221, 7p

مصطلحات موضوعية: WOMEN military personnel, MEDICAL needs assessment, PREMATURE labor, CHILDBIRTH, ODDS ratio, DOULAS, PRIMIPARAS

مستخلص: The number of women in the U.S. military is dramatically increasing. Similarly, the roles of active-duty women are greatly expanding, thus exposing them to new occupational risks. Determining the impact of pregnancy outcomes for women while in the military is difficult due to changing exposures over time, difficulty in utilizing appropriate comparison groups, and the lack of prospective investigations. Despite these limitations, it was concerning that the available data suggest that servicewomen delivering within 6 months of their first deployment have an increased preterm birth risk (adjusted odds ratio [aOR]: 2.1), and those with three prior deployments have an even greater risk (aOR: 3.8). Servicewomen also have an increased risk of hypertensive disorders with a rate of 13% compared with 5% in the general obstetric population. Furthermore, depression is higher for women who deploy after childbirth and are exposed to combat when compared with those who have not deployed since the birth of their child (aOR: 2.01). Due to the importance of this issue, prospective research designs are necessary to better understand and address the unique health care needs of this population. [ABSTRACT FROM AUTHOR]

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المؤلفون: Jakobsson, M.¹ maija.jakobsson@fimnet.fi, Gissler, M.², Paavonen, J.¹, Tapper, A.-M.¹

المصدر: BJOG: An International Journal of Obstetrics & Gynaecology. Jan2008, Vol. 115 Issue 1, p38-43. 6p. 3 Charts.

مصطلحات موضوعية: *RISK factors in premature labor, *PREMATURE labor, *CHILDBIRTH, *OBSTETRICS

مصطلحات جغرافية: FINLAND

مستخلص: Objective We examined the trends and risk factors of preterm delivery. Design Register-based retrospective cohort study from Finland. Setting National Medical Birth Register data during 1987–2005. Population The study population consisted of 1 137 515 deliveries, of which 59 025 were preterm (5.2%). Methods We calculated the population attributable risks for using the risk factor prevalence rates in the population. We further calculated odds ratios with 95% CI by multivariate logistic regression to adjust for confounders. Main outcome measures Preterm delivery rate subclassified into moderately preterm (32–36 weeks), very preterm (28–31 weeks) and extremely preterm (less than 28 weeks). Results Preterm delivery rates increased from 5.1% in the late 1980s to 5.4% in the late 1990s but then decreased to 5.2% for 2001–05. The proportion of extremely preterm deliveries decreased substantially by 12% ( P < 0.01). The greatest risk factors were multiplicity (OR 13.72, 95% CI 13.26–14.19), followed by elective delivery (OR 1.86, 95% CI 1.82–1.89), primiparity (OR 1.47, 95% CI 1.45–1.50), in vitro fertilisation treatment (OR 1.39, 95% CI 1.31–1.47), maternal smoking (OR 1.31, 95% CI 1.29–1.34) and advanced maternal age (OR 1.02, 95% CI 1.02–1.03 for each additional year of age). Prematurity rates decreased by 1.8% after adjusting for risk variables. Conclusions The rate of preterm delivery has not increased from 1987 to 2005 in Finland, while the risk for extremely preterm delivery has decreased. This finding is in contrast with recent trends in other countries. [ABSTRACT FROM AUTHOR]

المؤلفون: Hamilton, A. Rebecca L.^1,2 rebecca.hamilton@ki.se, Drzymalski, Dan M.³

المصدر: International Journal of Gynecology & Obstetrics. Apr2022, Vol. 157 Issue 1, p154-158. 5p.

مصطلحات موضوعية: *CESAREAN section, *INNER cities, *PREMATURE labor, *MEDICAL centers, *HELLP syndrome

مستخلص: Objective: To investigate factors associated with unscheduled cesarean delivery at one urban tertiary medical center. Methods: A retrospective chart review was performed on 11 162 deliveries between 2009 and 2019. The dependent variable was unscheduled cesarean delivery. Covariates examined included time of delivery, as well as several maternal and pregnancy-related factors. Results: There were a total of 7037 (63.1%) vaginal, 1133 (10.1%) elective cesarean, and 2992 (26.8%) unscheduled cesarean deliveries. Independent factors associated with increased odds for unscheduled cesarean delivery included daytime delivery (odds ratio [OR] 1.29, 95% confidence interval [CI] 1.18–1.42, P < 0.001); advanced maternal age (OR 1.40, 95% CI 1.26–1.56, P < 0.001); obesity (OR 1.04, 95% CI 1.03– 1.05, P < 0.001); history of previous cesarean delivery (OR 2.77, 95% CI 1.91–4.01, P < 0.001); hypertension (OR 1.72, 95% CI 1.27–2.32, P < 0.001); multiparity (OR 3.99, 95% CI 2.82–5.64, P < 0.001); pre-eclampsia (OR 1.96, 95% CI 1.33–2.89, P = 0.001); and HELLP (hemolysis, elevated liver enzymes and low platelet count) syndrome (OR 5.45, 95% CI 1.13–26.28, P = 0.035). Conclusion: Factors associated with unscheduled cesarean delivery in this study cohort included daytime delivery, advanced maternal age, obesity, hypertension, previous cesarean delivery, multiparity, preterm labor, pre-eclampsia, and HELLP syndrome. [ABSTRACT FROM AUTHOR]