المؤلفون: Qin, Wei^1,2 (AUTHOR), Shao, Ling^1,3 (AUTHOR), Wang, Jun² (AUTHOR), Zhang, Huan² (AUTHOR), Wang, Yao² (AUTHOR), Zhang, Xiaqing^2,4 (AUTHOR), Xie, Shaoyu² (AUTHOR), Pan, Fan² (AUTHOR), Cheng, Kai² (AUTHOR), Ma, Liguo² (AUTHOR), Chen, Yafei² (AUTHOR), Song, Jian¹ (AUTHOR), Gao, Dawei⁵ (AUTHOR), Chen, Zhichao⁵ (AUTHOR), Yang, Wei⁵ (AUTHOR), Zhu, Rui⁵ (AUTHOR), Su, Hong¹ (AUTHOR) suhong5151@sina.com

المصدر: Journal of Viral Hepatitis. Mar2024, Vol. 31 Issue 3, p143-150. 8p.

مصطلحات موضوعية: *PREMATURE labor, *LOW birth weight, *HEPATITIS B vaccines, *CHILDBIRTH, *PREMATURE infants, *BOOSTER vaccines

مستخلص: Previous studies did not provide substantial evidence for long‐term immune persistence after the hepatitis B vaccine (HepB) in preterm birth (PTB) children. Consequently, there is ongoing controversy surrounding the booster immunization strategy for these children. Therefore, we conducted a retrospective cohort study to evaluate the disparities in immune persistence between PTB children and full‐term children. A total of 1027 participants were enrolled in this study, including 505 PTB children in the exposure group and 522 full‐term children in the control group. The negative rate of hepatitis B surface antibody (HBsAb) in the PTB group was significantly lower than that in the control group (47.9% vs. 41.4%, p =.035). The risk of HBsAb‐negative in the exposure group was 1.5 times higher than that in the control group (adjusted odds ratio [aOR] = 1.5, 95% confidence interval [CI]: 1.1–2.0). The geometric mean concentration (GMC) of HBsAb was much lower for participants in the exposure group compared to participants in the control group (9.3 vs. 12.4 mIU/mL, p =.029). Subgroup analysis showed that the very preterm infants (gestational age <32 weeks) and the preterm low birth weight infants (birth weight <2000 g) had relatively low GMC levels of 3.2 mIU/mL (95% CI: 0.9–11.1) and 7.9 mIU/mL (95% CI: 4.2–14.8), respectively. Our findings demonstrated that PTB had a significant impact on the long‐term persistence of HBsAb after HepB vaccination. The very preterm infants (gestational age <32 weeks) and the preterm low birth weight infants (birth weight <2000 g) may be special populations that should be given priority for HepB booster vaccination. [ABSTRACT FROM AUTHOR]

المؤلفون: Gebreslasie, Kahsay Zenebe, Weldemariam, Solomon, Gebre, Gelawdyos, Zenebe, Dawit, Mehari, Mihreteab, Birhane, Aklil, Dewey, Rebecca Susan

المصدر: Scientific Reports; 1/16/2024, Vol. 14 Issue 1, p1-7, 7p

مصطلحات موضوعية: INTIMATE partner violence, LOW birth weight, BIRTH weight, PREGNANCY, PREMATURE labor, CHILDBIRTH, PREGNANT women

مصطلحات جغرافية: TIGRAY Kifle Hager (Ethiopia), ETHIOPIA

مستخلص: Intimate partner Violence (IPV) can affect any woman, irrespective of their economic status, religion, or culture. This is a human-rights issue and due to its prevalence and adverse effects on pregnancy and birth, it must be given greater attention. Further, there is a lack of data in the Tigray region about adverse birth outcomes due to intimate partner violence during pregnancy. The aim of this study was to assess intimate partner violence during pregnancy and its association with low birth weight and preterm birth in Tigray region. Across-sectional study design was used. 647 women were involved in the study. Simple random sampling techniques were employed to select health facilities and systematic sampling was used to select study participants. Data were entered using Epi info version 3.5.1 and was analyzed using SPSSversion 20. Logistic regression analysis was conducted to assess the association between exposure to intimate partner violence during pregnancy and preterm birth and low birth weight while adjusting for possible confounders. The prevalence of intimate partner violence during pregnancy was 7.3% and the prevalence of low birth weight and preterm birth were 18.5% and 10.8% respectively. There was a statistically significant association between exposure to intimate partner violence during pregnancy and low birth weight. After adjustment for socioeconomic status, women's habits and obstetric factors, the pregnant women who were exposed to intimate partner violence during pregnancy were two times more likely to have a child with a low birth weight (2.39 (95% CI: 1.26–4.55)). The prevalence of intimate partner violence during pregnancy, low birth weight, and preterm birth in this study was high. Women who experienced intimate partner violence during pregnancy had an increased risk of low birth weight. These findings justify a call to the federal minster of health to take measures aimed at avoiding intimate partner violence during pregnancy to reduce adverse birth outcomes. [ABSTRACT FROM AUTHOR]

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المؤلفون: Orimoloye, Helen T., He, Di, Li, Tong, Janzen, Carla, Barjaktarevic, Igor, Wang, Xuexia, Hansen, Johnni, Heck, Julia E.

المصدر: PLoS ONE; 1/2/2024, Vol. 19 Issue 1, p1-14, 14p

مصطلحات موضوعية: PREGNANCY complications, TRYPSIN inhibitors, LOW birth weight, CHILDBIRTH, POISSON regression, DELIVERY (Obstetrics), PREMATURE labor

مصطلحات جغرافية: DENMARK

مستخلص: Background: Alpha-1 antitrypsin deficiency (AATD) is related to developing lung and liver disease, but no large-scale studies examine its association with birth outcomes. Objective: We investigated the risk of pregnancy complications and adverse birth outcomes in mothers and children with AATD. Methods: Using a large cohort data of Danish mothers and children with AATD from 1973 to 2013 (n = 2,027,229), with 559 cases (305 mothers and 254 children). We conducted Poisson regression to examine associations between alpha-1 antitrypsin deficiency, adverse birth outcomes, and pregnancy complications in mothers and children. Results: AATD was related to term low birth weight [<2500g; Risk Ratio(RR) = 2.04, 95% confidence interval (CI): 1.50–2.79], lowest quartile of abdominal circumference at birth in children of non-smoking mothers (RR = 1.55, 95% CI: 1.14–2.11), delivery via Cesarean-section (RR = 1.59, 95% CI: 1.05–2.40), preterm birth (RR = 1.54, 95% CI: 1.19–2.00) and preeclampsia (RR = 2.64, 95% CI: 1.76–3.94). Conclusions: This emphasizes the need for mothers with AATD to be monitored closely during pregnancy to reduce the risk of adverse birth outcomes. Routine screening for alpha-1 antitrypsin in pregnancy may be considered among mothers with a pulmonary and liver disease history. [ABSTRACT FROM AUTHOR]

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العنوان البديل: Impacto dos programas de transferência de renda nos desfechos de nascimento e crescimento infantil: revisão sistemática. (Portuguese)

المؤلفون: Soares Lisboa, Cinthia, Sernizon Guimarães, Nathalia, Fortes Ferreira, Andrêa Jacqueline, Beck da Silva, Karine Brito, Oliveira Alves, Flávia Jôse, dos Santos Rocha, Aline, Ortelan, Naiá, Silva Texeira, Camila Silveira, Rocha Falcão, Ila, de Jesus Silva, Natanael, de Cássia Ribeiro-Silva, Rita, Barbosa dos Santos, Djanilson, Lima Barreto, Mauricio

المصدر: Revista Ciência & Saúde Coletiva; Aug2023, Vol. 28 Issue 8, p2417-2432, 16p

مصطلحات موضوعية: GROWTH of children, CHILDBIRTH, LOW birth weight, BIRTH weight, WEB databases, PREMATURE labor

الملخص (بالإنجليزية): To investigate the impact of cash transfer (CTs) on birth outcomes, including birth weight, low birth weight and prematurity, as well as child physical growth were included, as assessed by anthropometric indices in children under five years of age. Searching was performed using the PubMed/Medline, Embase, LILACS, Cochrane Library, Scopus and Web of Science databases. Quantitative observational, experimental and quasi-experimental. Eleven studies were included in the review. The majority (81.8%) were carried out in low-and middle-income countries and most involved conditional CTs (63.6%). Four were clinical trials and seven were observational studies. Conditional CTs were found to be associated with a reduction in height-for-age (-0.14; 95%CI -0.27, -0.02); (OR 0.85; 95%CI 0.77-0.94); (OR = 0.44; 95%CI 0.19-0.98), a significantly reduced chance of low weight-for-age (OR = 0.16; 95%CI -0.11-0.43), low weight-forheight (OR = -0.68; 95%CI -1.14, -0.21), and low weight-for-age (OR = 0.27; 95%CI 0.10; 0.71). Unconditional CTs were associated with reduced birth weight (RR = 0.71; 95%CI 0.63-0.81; p < 0.0001) and preterm births (RR = 0.76; 95%CI 0.69-0.84; p < 0.0001). Conditional CTs can positively influence birth outcomes and child growth. [ABSTRACT FROM AUTHOR]

Abstract (Portuguese): Investigar o impacto dos programas de tranferência de renda (CTs) nos desfechos ao nascer, incluindo peso ao nascer, baixo peso ao nascer e prematuridade, e crescimento físico infantil, avaliado pelos índices antropométricos de crianças menores de cinco anos. Revisão sistemática realizada nas bases de dados PubMed/Medline, Embase, LILACS, Cochrane Library, Scopus e Web of Science. Foram incluídos estudos quantitativos observacionais, experimentais e quasi-experimentais, com um total de 11 estudos na revisão. A maioria (81,8%) foi realizada em países de baixa e média rendas. Também na modalidade CT condicionais (63,6%). Quatro eram ensaios clínicos, e sete observacionais. Os CT condicionais estiveram associados a uma redução nos índices de altura-para-idade (-0,14; IC95% -0,27, -0,02); (OR 0,85; IC95% 0,77-0,94); (OR = 0,44; IC95% 0,19-0,98), redução significativa na chance de baixo peso-para-idade (OR = 0,16; IC95% -0,11-0,43), baixo peso-para-altura (OR = -0,68; IC95% -1,14, -0,21), e redução de peso para idade (OR = 0,27; IC95% 0,10; 0,71). CTs não condicionais foram associados à redução do baixo peso as nascer (RR = 0,71; IC95% 0,63-0,81; p < 0,0001), e de prematuros (RR = 0,76; IC95% 0,69-0,84; p < 0,0001). Os CTs condicionais podem influenciar positivamente os desfechos ao nascer e o crescimento infantil. [ABSTRACT FROM AUTHOR]

: Copyright of Revista Ciência & Saúde Coletiva is the property of Associacao Brasileira de Pos-Graduacao em Saude Coletiva and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Yim, Gyeyoon^1,2 (AUTHOR), Roberts, Andrea² (AUTHOR), Wypij, David^3,4,5 (AUTHOR), Kioumourtzoglou, Marianthi-Anna⁶ (AUTHOR), Weisskopf, Marc G^1,2 (AUTHOR) mweissko@hsph.harvard.edu

المصدر: International Journal of Epidemiology. Dec2021, Vol. 50 Issue 6, p1886-1896. 11p.

مصطلحات موضوعية: *LOW birth weight, *PREMATURE labor, *CHILDBIRTH, *PREGNANCY complications, *PREGNANCY

مستخلص: Background: Diethylstilbestrol (DES) is an endocrine-disrupting pharmaceutical prescribed to pregnant women to prevent pregnancy complications between the 1940s and 1970s. Although DES has been shown in animal studies to have multigenerational effects, only two studies have investigated potential multigenerational effects in humans on preterm birth (PTB), and none on low birthweight (LBW)-major determinants of later life health.Methods: Nurses' Health Study (NHS) II participants (G1; born 1946-64) reported their mothers' (G0) use of DES while pregnant with them. We used cluster-weighted generalized estimating equations to estimate odds ratios (OR) and 95% confidence intervals (CI) for risk of LBW and PTB among the grandchildren by grandmother use of DES. G1 birthweight and gestational age were considered to explore confounding by indication.Results: Among 54 334 G0-G1/grandmother-mother pairs, 973 (1.8%) G0 used DES during pregnancy with G1. Of the 128 275 G2 children, 4369 (3.4%) were LBW and 7976 (6.2%) premature. Grandmother (G0) use of DES during pregnancy was associated with an increased risk of G2 LBW [adjusted OR (aOR) = 3.09; 95% CI: 2.57, 3.72], that was reduced when restricted to term births (aOR = 1.59; 95% CI: 1.08, 2.36). The aOR for PTB was 2.88 (95% CI: 2.46, 3.37). Results were essentially unchanged when G1 birthweight and gestational age were included in the model, as well as after adjusting for other potential intermediate variables, such as G2 pregnancy-related factors.Conclusions: Grandmother use of DES during pregnancy is associated with an increased risk of LBW, predominantly through an increased risk of PTB. Results when considering G1 birth outcomes suggest this does not result from confounding by indication. [ABSTRACT FROM AUTHOR]

المؤلفون: Elci, Gulhan Gunes, Hanligil, Erhan, Elci, Erkan

المصدر: Annals of Medical of Research; Jun2023, Vol. 30 Issue 6, p671-677, 7p

مصطلحات موضوعية: CHILDBIRTH, SOCIOECONOMIC status, LOW birth weight, PREMATURE labor, CESAREAN section

مستخلص: Aim: Adolescent pregnancies constitute a very important health issue for maternal and fetal with social and economic consequences. The purpose of this study is to analyze the perinatal outcomes of adolescent pregnancies in a training and research hospital. Materials and Methods: Perinatal outcomes for adolescents between the ages of 10 and 19 years old and adults between the ages of 20 and 30 years old between 2015 and 2019 were evaluated and compared retrospectively, using an obstetric and neonatal database from Van Training and Research Hospital. Results: Cesarean section (CS) rates were 19,4 % vs. 30% in the adolescent and control groups, respectively (p<0.05). The rates of preterm delivery (PD), premature rupture of membranes (PROM), preeclampsia, and eclampsia were significantly higher among adolescents (p<0.05). After adjusting for maternal age, gravida, parity, hemoglobin level, education, socioeconomic status, and pregnancy follow-up, the rates of NVD (aOR 2.004, 95% CI 1.739-2.309), PB (aOR 1.419, 95% CI 1.122-1.794), PROM (aOR 4.401, 95% CI 3.066-6.319) and low birth weight (<2,500 g; aOR 2.480, 95% CI 1.442-4.264) were elevated in the adolescent group. Conclusion: Adolescent pregnancy is associated with increased risk of PD, low birth weight, PROM, fetal mortality, and preeclampsia in our study. In this study, which evaluated adolescent pregnancies, maternal and fetal outcomes, risk of preeclampsia increased among maternal outcomes, and it was found to be associated with preterm birth, low birth weight, premature rupture of the membrane and increased fetal mortality from fetal outcomes. However, there are different results between studies because there are many factors affecting the results. More studies are needed to confirm these results. There is a need for more studies on adolescent pregnancies with important maternal and fetal outcomes not only for our country but also for many countries. [ABSTRACT FROM AUTHOR]

: Copyright of Annals of Medical of Research is the property of Annals of Medical Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Yuan, Xiaosong¹ (AUTHOR), Gao, Yanfang² (AUTHOR) gyfg05@sina.com, Zhang, Ming² (AUTHOR), Long, Wei¹ (AUTHOR), Liu, Jianbing¹ (AUTHOR), Wang, Huiyan³ (AUTHOR), Yu, Bin¹ (AUTHOR) binyu@njmu.edu.cn, Xu, Jun¹ (AUTHOR) yyxujun@qq.com

المصدر: Clinica Chimica Acta. Feb2020, Vol. 501, p258-263. 6p.

مصطلحات موضوعية: *FETAL macrosomia, *PREMATURE labor, *FIBRIN fragment D, *PREGNANCY, *LOW birth weight, *CHILDBIRTH

مستخلص: • Plasma D-dimer levels in late pregnancy were positively associated with fetal growth indicators. • Increase in D-dimer quartiles were associated with an decreased risk for SGA, LBW and PTB infants. • Increase in D-dimer quartiles were associated with an increased risk for large for LGA and macrosomia infants. • D-dimer test in this study had risk evaluation value for obstetric outcomes. To investigate the association of D-dimer level during late pregnancy with birth outcomes in a Chinese population. A retrospective observational cohort study of 11,570 pregnant women who delivered in a single central hospital was conducted. Maternal plasma D-dimer levels at hospital admission and pregnancy outcomes were abstracted and analyzed from laboratory information system and hospital records, respectively. Maternal plasma D-dimer levels were associated with higher fetal growth indicators for the highest vs. lowest quartile (Q) of D-dimer (mean birth weight: 145.79 g, mean birth length: 0.11 cm, mean gestational age: 0.30 week). Increase in D-dimer quartiles were associated with an decreased risk for small for gestational age (SGA), low birth weight (LBW) and preterm birth (PTB) neonates, and with an increased risk for large for gestational age (LGA), and macrosomia infants (SGA: OR = 0.52, 95% CI: 0.43, 0.64; LBW: OR = 0.58, 95% CI: 0.38, 0.86; PTB: OR = 0.44, 95% CI: 0.35, 0.55; LGA: OR = 2.37, 95% CI: 2.01, 2.78; macrosomia: OR = 2.59, 95% CI, 2.06, 3.24; for Q4 vs. Q1). Maternal plasma D-dimer levels during late pregnancy were associated with birth outcomes and had risk evaluation value for these outcomes. [ABSTRACT FROM AUTHOR]

المؤلفون: Seabrook, Jamie A.^1,2,3,4,5,6 (AUTHOR), Smith, Alexandra¹ (AUTHOR), Clark, Andrew F.^4,6,7 (AUTHOR), Gilliland, Jason A.^{1,2,3,4,5,6,7,8} (AUTHOR) jgillila@uwo.ca

المصدر: Environmental Research. May2019, Vol. 172, p18-26. 9p.

مصطلحات موضوعية: *CHILDBIRTH, *PREMATURE labor, *PREGNANT women, *LOW birth weight, *GEOGRAPHIC information systems, *FOOD consumption, *FETAL macrosomia

مصطلحات جغرافية: ONTARIO, CANADA

مستخلص: A growing body of research has examined the association between exposure to environmental factors during pregnancy and adverse birth outcomes; however, many studies do not control for potential covariates and findings vary considerably. To test the relative influence of environmental factors including exposure to air pollution, major roads, highways, industry, parks, greenspaces, and food retailers on low birth weight (LBW) and preterm birth (PTB) in Southwestern Ontario (SWO), Canada, while accounting for medical (e.g., previous preterm birth, gestational diabetes), behavioral (e.g., alcohol, smoking), demographic (e.g., maternal age, body mass index), and neighborhood-level socioeconomic (e.g., household income, education) factors. This retrospective cohort study consisted of a large sample of pregnant women from SWO who gave birth to singleton newborns between February 2009 and February 2014 at London Health Sciences Centre. Data on maternal postal codes were entered into a Geographic Information System to map the distribution of maternal residences and determine selected characteristics of their neighborhood environments (i.e., socioeconomic, built, natural). These variables were developed based on postal codes where the mothers lived prior to giving birth. Logistic regression was used to assess the relative effects of the physical environment, socioeconomic status, clinical history, and behavioral risk factors on mothers having a LBW or PTB infant. Out of 25,263 live births, 5.7% were LBW and 7.5% were PTB. Exposure to sulfur dioxide was a top predictor of both LBW and PTB. For every one-unit increase in sulfur dioxide, the odds of a LBW and PTB were 3.4 (95% CI: 2.2, 5.2) and 2.0 (95% CI: 1.4, 3.0) times higher, after controlling for other variables in the model, respectively (p < 0.001). Previous PTB was also highly associated with both birth outcomes. Health care providers should be informed about the hazards of air pollution to developing fetuses so that recommendations can be made to their pregnant patients about limiting exposure when air quality is poor. • Out of 25,263 live births, 5.7% were low birth weight and 7.5% were preterm birth. • Maternal exposure to sulfur dioxide was a top predictor of adverse birth outcomes. • Previous preterm birth was also highly associated with both birth outcomes. [ABSTRACT FROM AUTHOR]

المؤلفون: Mascarenhas, Mariano¹, Sunkara, Sesh Kamal², Antonisamy, Belavendra³, Kamath, Mohan S.⁴ dockamz@gmail.com

المصدر: European Journal of Obstetrics & Gynecology & Reproductive Biology. Nov2017, p60-67. 8p.

مصطلحات موضوعية: *PREMATURE labor, *LOW birth weight, *OVUM donation, *CELLS, *CHILDBIRTH, *OBSTETRICS, *REPRODUCTION, *FERTILIZATION in vitro, *PREMATURE infants, *EVALUATION of medical care, *META-analysis, *PREGNANCY, *SYSTEMATIC reviews

مستخلص: Objectives: To perform a systematic review and meta-analysis of the known literature to assess whether the perinatal outcomes are different after oocyte donation (OD) compared to autologous oocyte (AO) in vitro fertilization (IVF) pregnancies.Study Design: A systematic literature search was done for studies published in English from 1980 to 2016. Studies comparing perinatal outcomes of pregnancies following fresh or frozen OD and AO IVF were included. Meta-analysis was performed using the Rev Man 5.3 software (Cochrane Collaboration) for the perinatal outcomes of PTB (<37 weeks), early PTB (<32 weeks), LBW (<2500g), very LBW (<1500g), and SGA (<10th centile). Six studies provided data on PTB, three studies on early PTB, five studies on LBW, four studies on very LBW and three studies on SGA after fresh embryo transfer. Two studies provided data on PTB, early PTB, LBW and very LBW after frozen embryo transfer.Results: There is an increased risk of PTB following fresh embryo transfer in OD pregnancies than in AO IVF pregnancies (OR 1.45, 95% CI 1.20-1.77). If the PTB risk is assumed to be to 9% for pregnancies following AO IVF, then OD pregnancies will have a PTB risk between 10.8% and 15.9%. Similarly, the risk of LBW is higher after fresh embryo transfer in OD pregnancies than AO IVF pregnancies (OR 1.34, 95% CI 1.12-1.60). If the assumed LBW risk is 9% for AO IVF pregnancies, then OD pregnancies have a LBW risk between 10.1% and 14.4%. There is an increased risk of early PTB (OR 2.14, 95% CI 1.40-3.25) and very LBW (OR 1.51, 95% CI 1.17-1.95) in a fresh embryo transfer after OD as compared to AO IVF pregnancies.Conclusions: There appears to be a higher risk of adverse perinatal outcomes following fresh OD compared to AO IVF pregnancies. [ABSTRACT FROM AUTHOR]

المؤلفون: Kamath, Mohan Shashikant¹ dockamz@gmail.com, Antonisamy, Belavendra², Mascarenhas, Mariano³, Sunkara, Sesh Kamal⁴

المصدر: Reproductive BioMedicine Online (Elsevier Science). Sep2017, Vol. 35 Issue 3, p318-324. 7p.

مصطلحات موضوعية: *RISK factors in premature labor, *LOW birth weight, *EMBRYO implantation, *FERTILIZATION in vitro, *CHILDBIRTH, RISK factors

مستخلص: A higher risk of pregnancy complications occurs after assisted reproductive techniques compared with spontaneously conceived pregnancies. This is attributed to the underlying infertility and assisted reproduction technique procedures involved during treatment. It is a matter of interest whether use of donor oocytes affects perinatal outcomes compared with pregnancies after autologous IVF. Anonymized data were obtained from the Human Fertilization and Embryology Authority. The analysis included 5929 oocyte donation and 127,856 autologous IVF live births. Data from all women who underwent donor oocyte recipient or autologous IVF cycles, both followed with fresh embryo transfer, were analysed to compare perinatal outcomes of preterm birth (PTB) and low birthweight (LBW) after singleton and multiple live births. The risk of adverse perinatal outcomes after oocyte donation was increased: adjusted OR (aOR) 1.56, 99.5% CI 1.34 to 1.80 for PTB and aOR 1.43, 99.5% CI 1.24 to 1.66 for LBW were significantly higher after oocyte donation compared with autologous IVF singletons. The adjusted odds PTB (aOR 1.21, 99.5% CI 1.02 to 1.43) was significantly higher after oocyte donation compared with autologous IVF multiple births. Analysis of this large dataset suggests significantly higher risk of PTB and LBW after ooctye donation compared with autologous IVF pregnancies. [ABSTRACT FROM AUTHOR]