التفاصيل البيبلوغرافية
| العنوان: |
Interhemispheric Pediatric Meningioma, YAP1 Fusion-Positive. |
| المؤلفون: |
Esposito, Silvia, Marucci, Gianluca, Antonelli, Manila, Miele, Evelina, Modena, Piergiorgio, Giagnacovo, Marzia, Massimino, Maura, Biassoni, Veronica, Taddei, Matilde, Schiariti, Marco Paolo, Doniselli, Fabio Martino, Moscatelli, Marco, Chiapparini, Luisa, Pollo, Bianca |
| المصدر: |
Diagnostics (2075-4418); Oct2022, Vol. 12 Issue 10, p2367-N.PAG, 7p |
| مصطلحات موضوعية: |
MENINGIOMA, CHILD patients |
| مستخلص: |
Meningiomas are uncommon in children and usually arise in the context of tumor-predisposing syndromes. Recently, YAP1-fusions have been identified for the first time as potential NF2-independent oncogenic drivers in the development of meningiomas in pediatric patients. We report a case of a YAP1-fusion-positive atypical meningioma in a young child and compare it with the previous ones reported. Extending the clinico-pathological features of YAP1-fused meningiomas, we suggest additional clues for diagnosis and emphasize the urgent need for an integrated multilayered diagnostic approach, combining data from histological and molecular analyses, neuroradiology, and clinical findings. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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