المؤلفون: Cornelis M. van Tilburg, Ruth Witt, Melanie Heiss, Kristian W. Pajtler, Christoph Plass, Isabel Poschke, Michael Platten, Inga Harting, Oliver Sedlaczek, Angelika Freitag, David Meyrath, Lenka Taylor, Gnana Prakash Balasubramanian, Natalie Jäger, Elke Pfaff, Barbara C. Jones, Till Milde, Stefan M. Pfister, David T. W. Jones, Annette Kopp-Schneider, Olaf Witt

المصدر: BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)

مصطلحات موضوعية: Entinostat, Nivolumab, Child, Bayesian design, Biomarker, Phase I/II, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s12885-020-07008-8Test; https://doaj.org/toc/1471-2407Test

الوصول الحر: https://doaj.org/article/ef3446831b4b419a8809bb6d0c15b3eaTest

المؤلفون: Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P.B. Dubois, Alexander Crane, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, François Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Volker Hovestadt, Claudia L. Kleinman, Henry Long, David T.W. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix

المصدر: Cancer Res

مصطلحات موضوعية: Adult, Male, Transcriptional Activation, Cancer Research, Proto-Oncogene Proteins c-ets, Carcinogenesis, Medizin, Forkhead Transcription Factors, Oncogenes, Article, Epigenesis, Genetic, Cell Transformation, Neoplastic, Oncology, Neoplasms, Humans, Child, Cell Proliferation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b04fde1eafeb27aba2cd478be2c63a8Test
https://europepmc.org/articles/PMC9437574Test/

المؤلفون: Till Milde, Maximilian Y Deng, David E. Reuss, Andrew M. Donson, Martin U. Schuhmann, Felix Sahm, Dominik Sturm, Martin Sill, Andreas von Deimling, Josef Zamecnik, Martin Ebinger, David T.W. Jones, Andrea Wittmann, David Sumerauer, Adam L. Green, Chris Jones, Damian Stichel, Stefan M. Pfister, Barbara C Jones, Andrey Golanov, Cornelis M. van Tilburg, Andrey Korshunov, Gnana Prakash Balasubramanian, Elke Pfaff, Marina Ryzhova, Olaf Witt, Christof M. Kramm, Jonas Ecker, Jens Schittenhelm, Stephan Tippelt

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications

مصطلحات موضوعية: Male, Receptor, Platelet-Derived Growth Factor alpha, Transcription, Genetic, Somatic cell, viruses, Medizin, General Physics and Astronomy, Kaplan-Meier Estimate, CDKN2A, Cancer genomics, Cluster Analysis, Child, Gene Rearrangement, Radiation, Multidisciplinary, biology, virus diseases, Glioma, Middle Aged, Gene Expression Regulation, Neoplastic, Histone, Female, Chromosome Deletion, biological phenomena, cell phenomena, and immunity, Adult, IDH1, Adolescent, Science, chemical and pharmacologic phenomena, Article, General Biochemistry, Genetics and Molecular Biology, Young Adult, medicine, Humans, Epigenetics, Gene, Cyclin-Dependent Kinase Inhibitor p16, Cyclin-Dependent Kinase Inhibitor p15, Medulloblastoma, Genome, Human, business.industry, Gene Amplification, General Chemistry, DNA Methylation, biochemical phenomena, metabolism, and nutrition, medicine.disease, CNS cancer, Gene expression profiling, biology.protein, Cancer research, Neoplasm Recurrence, Local, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208d52317283be4701383edc5340a13aTest
https://doi.org/10.1038/s41467-021-25708-yTest

المؤلفون: Steffen Hirsch, Caroline Hutter, Bianca Goemans, Kristian W. Pajtler, David Reuss, Gabriele Calaminus, Gnana Prakash Balasubramanian, Nicola Dikow, C. Michel Zwaan, Arndt Borkhardt, David T.W. Jones, Birgit Burkhardt, Matthias Schwab, Ingrid Øra, Ines B. Brecht, Uta Dirksen, Christian Sutter, Kathrin Schramm, Roman Tremmel, Bernarda Kazanowska, Peter Lichter, M. Scheer, Gudrun Fleischhack, André O. von Bueren, Mirjam Blattner-Johnson, David Capper, Felix Sahm, Simone Fulda, Natalie Jäger, Nicolas U. Gerber, Olaf Witt, Jan-Henning Klusmann, Irene Schmid, Petra Fiesel, Matthias Fischer, Roland Meisel, Stefan M. Pfister, Michaela Nathrath, Cornelis M. van Tilburg, Angelika Eggert, Sebastian Stark, Christof M. Kramm, Elke Pfaff, Kerstin Grund, Arend von Stackelberg, Andrej Lissat, Peter Vorwerk, Petra Ketteler, Angelika Freitag, Olli Lohi, Michael T. Meister, Ruth Witt, Norbert Graf, Annette Kopp-Schneider, Pascal D. Johann, Dominik T. Schneider, Karin P.S. Langenberg, Simone Hettmer, Dirk Reinhardt, Antonis Kattamis, Andreas E. Kulozik, Andreas von Deimling, Jan J. Molenaar, Wilhelm Wößmann, Maria Filippidou, Stephan Tippelt, Frank Westermann, Stephan Wolf, Michael C. Frühwald, Barbara C. Jones, Ewa Koscielniak, Till Milde, Stefanie Hecker-Nolting, Dietrich von Schweinitz

المساهمون: Pediatrics, Tampere University, Department of Paediatrics, BioMediTech

المصدر: Cancer Discovery, 11(11), 2764-2779. American Association for Cancer Research Inc.
Cancer discovery, Vol. 11, No 11 (2021) pp. 2764-2779

مصطلحات موضوعية: Prioritization, medicine.medical_specialty, Treatment response, 3122 Cancers, Medizin, MEDLINE, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, 3123 Gynaecology and paediatrics, Internal medicine, Neoplasms, medicine, Humans, Prospective Studies, Registries, Medical diagnosis, Precision Medicine, Child, 030304 developmental biology, 0303 health sciences, ddc:618, business.industry, Cancer, medicine.disease, Confidence interval, Progression-Free Survival, ddc, 3. Good health, Oncology, Precision oncology, 030220 oncology & carcinogenesis, Molecular targets, 3111 Biomedicine, business

وصف الملف: application/pdf; fulltext

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3aa2e6219234f552ef0d4f152d58341Test
https://pubmed.ncbi.nlm.nih.gov/34725088Test

المؤلفون: Barbara C. Jones, David T.W. Jones, Oliver Sedlaczek, Isabel Poschke, Till Milde, Melanie Heiss, Olaf Witt, Kristian W. Pajtler, Lenka A. Taylor, Annette Kopp-Schneider, Michael Platten, Inga Harting, Christoph Plass, Stefan M. Pfister, Natalie Jäger, David Meyrath, Gnana Prakash Balasubramanian, Ruth Witt, Cornelis M. van Tilburg, Elke Pfaff, Angelika Freitag

المصدر: BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Pyridines, Group B, chemistry.chemical_compound, Study Protocol, 0302 clinical medicine, Surgical oncology, HDAC, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Checkpoint inhibition, Medicine, Precision Medicine, Child, education.field_of_study, Entinostat, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Phase I/II, Nivolumab, Treatment Outcome, Drug development, 030220 oncology & carcinogenesis, Benzamides, Biomarker (medicine), Female, Drug Monitoring, Medical Futility, medicine.medical_specialty, Adolescent, Population, Bayesian design, lcsh:RC254-282, 03 medical and health sciences, Young Adult, Refractory, Internal medicine, Genetics, Biomarkers, Tumor, Humans, education, Dose-Response Relationship, Drug, business.industry, Bayes Theorem, Biomarker, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Mutation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a221c569d3b984612ec35962d2e3b66fTest
https://pubmed.ncbi.nlm.nih.gov/32503469Test

المؤلفون: Volker Hovestadt, Paul A. Northcott, Kyle Pedro, Sebastian Brabetz, Susanne Gröbner, Gnana Prakash Balasubramanian, Stefan M. Pfister, Huriye Seker-Cin, Sarah Leary, Peter Lichter, Karina Bloom, Madison W. Nakamoto, Jan Koster, Andrey Korshunov, Stacey Hansen, Joyoti Dey, Andrew D. Strand, Marcel Kool, Bonnie Cole, Fiona Pakiam, Emily J. Girard, Norman Mack, David T.W. Jones, Lukas Chavez, Sally Ditzler, Benjamin Schwalm, James M. Olson

المساهمون: Oncogenomics, CCA - Imaging and biomarkers

المصدر: Nature Medicine
Nature medicine, 24(11), 1752-1761. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Male, Genomics, medicine.disease_cause, Pediatrics, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Child, Biological Specimen Banks, Mutation, business.industry, Brain Neoplasms, Cancer, General Medicine, DNA Methylation, medicine.disease, Biobank, Immunohistochemistry, Xenograft Model Antitumor Assays, 3. Good health, 030104 developmental biology, Child, Preschool, DNA methylation, Cancer research, Pediatric Brain Tumor, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3e4bf3088822b533e30bb1e3cf8f76Test
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85055262681&origin=inwardTest

المؤلفون: Stephanie Knirsch, Till Milde, Michael C. Frühwald, Martin Jakobs, Martin U. Schuhmann, Peter Lichter, Michael Karremann, Angelika Eggert, Cornelis M. van Tilburg, Christof M. Kramm, Hendrik Witt, Karl L. Kiening, David T.W. Jones, Ruth Witt, Konrad Bochennek, Mirjam Blattner-Johnson, Sebastian Stark, Martin Ebinger, Heidi Bächli, Pablo Hernáiz Driever, Markus Metzler, André O. von Bueren, Christel Herold-Mende, Elke Pfaff, Ulrich W. Thomale, Torsten Pietsch, Olaf Witt, Kristian W. Pajtler, Stefan M. Pfister, David E. Reuss, Petra Fiesel, Barbara C. Worst, Matthias Dürken, Thorsten Simon, Ahmed El Damaty, Gnana Prakash Balasubramanian

المصدر: European journal of cancer, Vol. 114 (2019) pp. 27-35

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, medicine.medical_specialty, Fatal outcome, Adolescent, Registry study, medicine.medical_treatment, Biopsy, Newly diagnosed, Targeted therapy, 03 medical and health sciences, Molecular profiling, 0302 clinical medicine, RNA analysis, Pediatric diffuse intrinsic pons glioma, medicine, Brain Stem Neoplasms, Humans, Prospective Studies, Precision Medicine, Brainstem biopsy, Child, ddc:618, medicine.diagnostic_test, business.industry, Glioma, Brain Stem Neoplasms / surgery, Precision medicine, 3. Good health, Glioma / surgery, 030104 developmental biology, Oncology, Biopsy / methods, 030220 oncology & carcinogenesis, Child, Preschool, Female, Radiology, Brainstem, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb73582a1675504f194b2a7b38b7d418Test
https://pubmed.ncbi.nlm.nih.gov/31022591Test

المؤلفون: Benedikt Brors, Sasithorn Chotewutmontri, Stephan Wolf, Johannes H. Schulte, Michael C. Frühwald, Ewa Koscielniak, Andreas von Deimling, Stefan M. Pfister, Claus R. Bartram, David T.W. Jones, Matthias Schlesner, Birgit Burkhardt, Miream Boudalil, Lenka A. Taylor, Barbara C. Worst, Stefan S. Bielack, Dirk Reinhardt, David Capper, Thomas Klingebiel, Andreas E. Kulozik, Peter Lichter, André O. von Bueren, Olaf Witt, Matthias Schwab, Matthias Fischer, Heribert Jürgens, Till Milde, Frank Westermann, Barbara Hutter, Arend von Stackelberg, Tobias Borst, Petra Fiesel, Arndt Borkhardt, Melanie Bewerunge-Hudler, Wilhelm Wößmann, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz Driever, Simone Fulda, Christian Sutter, Michaela Nathrath, Christof M. Kramm, Matthias Schick, Uta Dirksen, Cornelis M. van Tilburg, Roman Tremmel, Roland Meisel, Ruth Witt, Sabine Schmidt, Elke Pfaff, Angelika Freitag, Gnana Prakash Balasubramanian, Christopher Previti, Jan-Henning Klusmann, Angelika Eggert

المصدر: European Journal of Cancer, Vol. 65 (2016) pp. 91-101

مصطلحات موضوعية: 0301 basic medicine, Oncology, Pilot phase, Adult, Male, Cancer Research, medicine.medical_specialty, Microarray, Adolescent, medicine.medical_treatment, Druggability, Medizin, Pilot Projects, Bioinformatics, Deep sequencing, Targeted therapy, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Paediatric cancer, Internal medicine, Neoplasms, medicine, Humans, Molecular Targeted Therapy, ddc:610, Precision Medicine, Child, ddc:618, business.industry, Gene Expression Profiling, Neoplasms/drug therapy/genetics, High-Throughput Nucleotide Sequencing, Infant, Precision Medicine/methods, Precision medicine, medicine.disease, 3. Good health, 030104 developmental biology, Molecular Diagnostic Techniques, 030220 oncology & carcinogenesis, Child, Preschool, Female, Sarcoma, business, Molecular Targeted Therapy/methods

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00abab1747f1e16993a9c4bc42452a65Test
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/72900Test