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المصدر: Virology. 562:128-141
مصطلحات موضوعية: Rhinovirus, Picornavirus, Protein Conformation, viruses, Biology, medicine.disease_cause, Antiviral Agents, Substrate Specificity, Viral Proteins, chemistry.chemical_compound, Eukaryotic translation, Virology, Cleave, medicine, Humans, Amino Acid Sequence, Adaptor Proteins, Signal Transducing, Enterovirus, Methionine, EIF4G, Poliovirus, Genetic Variation, biology.organism_classification, Cysteine Endopeptidases, chemistry, Biochemistry, Virion assembly, Eukaryotic Initiation Factor-4G, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383529bffe662fb2773cde3ad54d9453Test
https://doi.org/10.1016/j.virol.2021.07.008Test -
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المؤلفون: Wyatt W. Yue, Sabrina Mackinnon, Melanie Walter, Raina Yamamoto, William Foster, Sylvia Roloff, Anke Schumann, Sarah C. Grünert, Lisa Stübbe, Ali Alasmari, Ute Spiekerkoetter, Osama A. Obaid, Eissa Faqeih, Allan M. Lund, Christina Pontes, Corinne Gemperle-Britschgi, Jörn Oliver Sass, Natalie Weinhold
المصدر: Biochimie. 183:55-62
مصطلحات موضوعية: 0301 basic medicine, Coenzyme A, Mutation, Missense, Ketone Bodies, Crystallography, X-Ray, Bioinformatics, medicine.disease_cause, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, medicine, Humans, Missense mutation, Succinyl-CoA, OXCT1, Mutation, 030102 biochemistry & molecular biology, business.industry, Brain Diseases, Metabolic, Inborn, Metabolic acidosis, General Medicine, medicine.disease, Ketoacidosis, 030104 developmental biology, chemistry, Neurodevelopmental Disorders, Inborn error of metabolism, Coenzyme A-Transferases, Acidosis, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf49788580b3d54a2a07377626afd22fTest
https://doi.org/10.1016/j.biochi.2021.02.003Test -
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المؤلفون: W. Foster, G Arruda Bezerra, T. Krojer, Manshu Tang, Huber Kvm., Kent Lai, L. Diaz-Saez, Sabrina Mackinnon, Wyatt W. Yue, F. von Delft, Paul Brennan
المصدر: ACS Chemical Biology
مصطلحات موضوعية: Galactosemias, 0301 basic medicine, Protein Conformation, Allosteric regulation, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Galactokinase, 03 medical and health sciences, chemistry.chemical_compound, medicine, Humans, Enzyme Inhibitors, Binding site, biology, 010405 organic chemistry, Chemistry, Galactosemia, Rational design, Mevalonate kinase, Active site, Articles, General Medicine, medicine.disease, 0104 chemical sciences, 030104 developmental biology, Galactose, biology.protein, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6526484f4e04cc09ef4d380ce28a82Test
https://doi.org/10.1021/acschembio.0c00498Test -
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المؤلفون: I. M. Ferreira, Wyatt W. Yue, D. S. Froese, L. Shrestha, T. J. McCorvie, M. Tu, Seungil Han, Paula M. Loria, A. P. Berg
مصطلحات موضوعية: Conformational change, chemistry.chemical_compound, Glycogenin, Glucose 6-phosphate, chemistry, Biochemistry, Glycogen, biology, Phosphatase, Allosteric regulation, biology.protein, Phosphorylation, Glycogen synthase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::59da5a15b680c88b18b55d4f27839ec4Test
https://doi.org/10.1101/2021.11.12.468446Test -
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المؤلفون: Alain Martelli, Claire Strain-Damerell, Henry J. Bailey, Christine Bulawa, Xiaodi Yu, Seungil Han, Wyatt W. Yue, Nicholas G. Fox, Joseph F. Nabhan, Xidong Feng
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Nature Communicationsمصطلحات موضوعية: Iron-Sulfur Proteins, Models, Molecular, Scaffold protein, inorganic chemicals, Iron, Science, 010402 general chemistry, 01 natural sciences, Iron-sulfur cluster assembly complex, digestive system, Article, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Iron-Binding Proteins, lcsh:Science, 030304 developmental biology, 0303 health sciences, biology, Cysteine desulfurase, Activator (genetics), Cryoelectron Microscopy, fungi, SAXS, Recombinant Proteins, Mitochondria, 0104 chemical sciences, 3. Good health, Cell biology, Carbon-Sulfur Lyases, Zinc, chemistry, Friedreich Ataxia, Mitochondrial matrix, Enzyme mechanisms, Frataxin, biology.protein, lcsh:Q, ISCU, Sulfur
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ea331aa8af6309e6f2c081bd2451e1Test
https://doaj.org/article/8abcf6459af9457bb7545657bbc6ed8dTest -
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المؤلفون: Wyatt W. Yue, Alain Martelli, Theresa Towle, Christine Bulawa, Joseph F. Nabhan, Renea Gooch, Xidong Feng, Tiffany Ma, Nicholas G. Fox, Jaimeen D. Majmudar
المصدر: MedChemComm. 10:209-220
مصطلحات موضوعية: Pharmacology, biology, 010405 organic chemistry, Organic Chemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, Interactome, Cofactor, 0104 chemical sciences, Serine, Chemistry, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Lipoic acid, Acyl carrier protein, Biosynthesis, chemistry, Drug Discovery, biology.protein, Molecular Medicine, lipids (amino acids, peptides, and proteins), Phosphopantetheine, Biogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a55720aed23cd65b2fdf1a60e5461cfTest
https://doi.org/10.1039/c8md00489gTest -
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المؤلفون: Alexander Holenstein, W. Foster, Arindam Talukdar, D. Sean Froese, Bing Xie, Wyatt W. Yue, Gustavo Arruda Bezerra, Céline Bürer, Debomita Bhattacharya, Lei Shi, Seraina Lutz, Ayan Mukherjee, Kevin G. Hicks, Jared Rutter, Peter Brown, Minkui Luo, Dipika Sarkar
المساهمون: University of Zurich, Froese, D Sean, Yue, Wyatt W
المصدر: Biochimie
مصطلحات موضوعية: 0301 basic medicine, S-Adenosylmethionine, 1303 Biochemistry, Methylenetetrahydrofolate reductase deficiency, 5,10-Methylenetetrahydrofolate reductase, Drug-development, Allosteric regulation, 610 Medicine & health, Reductase, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, Sinefungin, Allosteric Regulation, Protein Domains, Enzymatic inhibition, medicine, Humans, Enzyme Inhibitors, Methylenetetrahydrofolate Reductase (NADPH2), Methionine, 030102 biochemistry & molecular biology, biology, Small molecules, General Medicine, medicine.disease, Small molecule, digestive system diseases, One-carbon metabolism, 030104 developmental biology, chemistry, 10036 Medical Clinic, Docking (molecular), Methylenetetrahydrofolate reductase, biology.protein
وصف الملف: 1_s2.0_S0300908421000092_main.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef61fcca8498f1f66e36e94dcc833f49Test
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المؤلفون: Gopalakrishnan Bulusu, Robert J. Desnick, David F. Bishop, W. Foster, Siladitya Padhi, Arijit Roy, Wyatt W. Yue, Elzbieta Rembeza, Harry A. Dailey, Jason R. Marcero, Gustavo Arruda Bezerra, Henry J. Bailey
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Protoporphyria, Erythropoietic, Protein Conformation, Science, Protein domain, General Physics and Astronomy, Heme, Plasma protein binding, Molecular Dynamics Simulation, Crystallography, X-Ray, Isozyme, Catalysis, Gene Expression Regulation, Enzymologic, Article, General Biochemistry, Genetics and Molecular Biology, Substrate Specificity, Frameshift mutation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Protein structure, Protein Domains, Transferases, Catalytic Domain, Humans, lcsh:Science, X-ray crystallography, Multidisciplinary, biology, Chemistry, Active site, Genetic Diseases, X-Linked, General Chemistry, ALAS2, Kinetics, 030104 developmental biology, Enzyme mechanisms, biology.protein, Biophysics, lcsh:Q, Acyl Coenzyme A, 030217 neurology & neurosurgery, 5-Aminolevulinate Synthetase, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285537360df796d460f3e2ba3ac1a931Test
https://doi.org/10.1038/s41467-020-16586-xTest -
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المؤلفون: Michiko E. Taga, Sabrina Mackinnon, D. Sean Froese, Olga M. Sokolovskaya, Henry J. Bailey, Wyatt W. Yue, Tanja Plessl, Matthias R. Baumgartner
المساهمون: University of Zurich, Taga, Michiko E
مصطلحات موضوعية: 0301 basic medicine, Biochemistry & Molecular Biology, 1303 Biochemistry, Vitamin B-12, 1.1 Normal biological development and functioning, Coenzymes, 610 Medicine & health, Context (language use), Cobamide, Biochemistry, Cobalamin, Cofactor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Mutase, Underpinning research, polycyclic compounds, Humans, Vitamin B12, Vitamin B(12), 030304 developmental biology, Nutrition, chemistry.chemical_classification, 0303 health sciences, Methylmalonic aciduria, 030102 biochemistry & molecular biology, biology, Chemistry, Methylmalonyl-CoA mutase, nutritional and metabolic diseases, Methylmalonyl-CoA Mutase, General Medicine, 3. Good health, Vitamin B 12, Kinetics, 030104 developmental biology, Enzyme, 10036 Medical Clinic, biology.protein, Biochemistry and Cell Biology, 030217 neurology & neurosurgery, Function (biology), MMUT
وصف الملف: application/pdf; nihms_1618799.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f2d8b2c6a727b4a2f45830438cf4a5Test
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المؤلفون: Elzbieta Rembeza, D. Sean Froese, Terttu Suormala, Anselm Erich Oberholzer, Oktawia Borkowska, Wyatt W. Yue, Jolanta Kopec, Gustavo Arruda Bezerra, Rod Chalk, Seraina Lutz, Matthias R. Baumgartner
المساهمون: University of Zurich, Froese, D Sean
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Folding, S-Adenosylmethionine, General Physics and Astronomy, Reductase, Crystallography, X-Ray, Mass Spectrometry, chemistry.chemical_compound, 0302 clinical medicine, Protein structure, X-Ray Diffraction, Catalytic Domain, Phosphorylation, lcsh:Science, Multidisciplinary, biology, Chemistry, 3100 General Physics and Astronomy, Recombinant Proteins, Biochemistry, Science, Protein domain, Allosteric regulation, 610 Medicine & health, 1600 General Chemistry, Molecular Dynamics Simulation, General Biochemistry, Genetics and Molecular Biology, Article, Evolution, Molecular, 03 medical and health sciences, Biosynthesis, Protein Domains, 1300 General Biochemistry, Genetics and Molecular Biology, Scattering, Small Angle, Humans, Amino Acid Sequence, Protein Structure, Quaternary, Methylenetetrahydrofolate Reductase (NADPH2), Methionine, General Chemistry, digestive system diseases, Kinetics, 030104 developmental biology, 10036 Medical Clinic, Methylenetetrahydrofolate reductase, biology.protein, lcsh:Q, 030217 neurology & neurosurgery, NADP
وصف الملف: 41467_2018_Article_4735.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c668c6b07c00337b17f534542d0bceTest
http://link.springer.com/article/10.1038/s41467-018-04735-2Test