نتائج البحث - "Time to peak"

1

Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

المؤلفون: Kenneth K.W. To, Jiang Ma, Stella Chai, Chunyuan Zhang, Chun Yin, Sheng Yao, Xu Wu, Thomas Efferth, Yang Ye, Onat Kadioglu, Ge Lin

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1885-1902 (2021)

مصطلحات موضوعية: ABCC1, ATP binding cassette subfamily C member 1, IC50, half maximal inhibitory concentration, Multidrug resistance, Pharmacology, NADPH, reduced nicotinamide adenine dinucleotide phosphate, F, bioavailability, chemistry.chemical_compound, PCR, polymerase chain reaction, 0302 clinical medicine, MDR, multidrug resistance, ECL, electrochemiluminescence, t1/2, elimination half-life, LC–MS, liquid chromatography coupled with mass spectrometry, N.D., not detected, General Pharmacology, Toxicology and Pharmaceutics, BBB, blood–brain barrier, media_common, ATF3, activating transcription factor 3, 0303 health sciences, Chemistry, ABC, ATP-binding cassette, NMPA, National Medical Products Administration, PXR, pregnane X receptor, SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, HBSS, Hankʹs balanced salt solution, ABCB1, Combination chemotherapy, Prodrug, Marsdenia tenacissima, Cmax, peak concentration, Paclitaxel, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, 030220 oncology & carcinogenesis, BHI, brain heart infusion, Original Article, AUC0–∞, area under plasma concentration vs. time curve, MRT, mean residence time, Drug, media_common.quotation_subject, RM1-950, Vd, volume of distribution, ABCB1, ATP binding cassette subfamily B member 1, UIC-2, mouse monoclonal ABCB1 antibody, ABCG2, ATP binding cassette subfamily G member 2, CYP, cytochrome P450 isozyme, PI, propidium iodide, TEER, transepithelial electrical resistance, 03 medical and health sciences, PBS, phosphate buffer saline, FBS, fetal bovine serum, Dox, doxorubicin, In vivo, POP, polyoxypregnane, medicine, 030304 developmental biology, EVOM, epithelial tissue voltohmmeter, Tmax, time for peak concentration, Cancer, LBE, lowest binding energy, PE, phycoerythrin, medicine.disease, Multiple drug resistance, Polyoxypregnane, Papp, apparent permeability, N.A., not applicable, Cancer cell, H&E, hematoxylin and eosin, MDR1a, multidrug resistance protein 1a, Therapeutics. Pharmacology, qPCR, quantitative PCR, M. tenacissima, Marsdenia tenacissima, CL, clearance, SD, standard derivation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10ca45cdbb87dcf2ef29e5865d5f864Test
https://doi.org/10.1016/j.apsb.2020.12.021Test

2

The effects of sodium bicarbonate supplementation at individual time-to-peak blood bicarbonate on 4-km cycling time trial performance in the heat

المؤلفون: Lewis A. Gough, William H Gurton, Jake J Williams, Josh W. Newbury

المصدر: European journal of sport science. 22(12)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53403470f6ee83d0ffaed234eda0cd08Test
https://pubmed.ncbi.nlm.nih.gov/34704539Test

3

Time to Peak Glucose and Peak C-Peptide During the Progression to Type 1 Diabetes in the Diabetes Prevention Trial and TrialNet Cohorts

المؤلفون: Jay M. Sosenko, Mario M. Cleves, Wayne V. Moore, Jerry P. Palmer, Michael G. Voss, Helena Elding Larsson, Heba M. Ismail, Carmella Evans-Molina, David Cuthbertson, Andrea K. Steck, Ping Xu, Mark A. Atkinson, Maria J. Redondo, Markus Lundgren

المصدر: Diabetes Care

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a6c95eb20c7a0f59b91f8e59054943Test
https://doi.org/10.2337/figshare.14974563.v2Test

4

The Influence of Supplemental Dietary Linoleic Acid on Skeletal Muscle Contractile Function in a Rodent Model of Barth Syndrome

المؤلفون: Madison Farago, Mario Elkes, Paul J. LeBlanc, Daislyn Vidal, Steven M. Claypool, Ryan Modafferi, Martin Andonovski

المصدر: Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4996725fdfe48caf55c0508477b2acTest
https://www.frontiersin.org/articles/10.3389/fphys.2021.731961/fullTest

5

The time to peak blood bicarbonate (HCO3–), pH, and the strong ion difference (SID) following sodium bicarbonate (NaHCO3) ingestion in highly trained adolescent swimmers

المؤلفون: S. Andy Sparks, Richard J Chessor, Lars R. McNaughton, Josh W. Newbury, Matthew Cole, Adam L. Kelly, Lewis A. Gough

المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0248456 (2021)

مصطلحات موضوعية: Male, Physiology, Adolescents, Strong ion difference, chemistry.chemical_compound, Families, 0302 clinical medicine, Medicine and Health Sciences, Ingestion, Public and Occupational Health, Children, Acid-Base Equilibrium, Multidisciplinary, Stomach, Nausea, Hydrogen-Ion Concentration, Sports Science, Body Fluids, Chemistry, Blood, Physical Sciences, Medicine, Time to peak, Female, Anatomy, Research Article, Adolescent, Science, Bicarbonate, Acid–base homeostasis, Performance-Enhancing Substances, 03 medical and health sciences, Animal science, Eructation, Humans, Sports and Exercise Medicine, Exercise, Personal time, Swimming, Nutrition, Sodium bicarbonate, Biological Locomotion, Chemical Compounds, Biology and Life Sciences, 030229 sport sciences, Physical Activity, Diet, Gastrointestinal Tract, Bicarbonates, Sodium Bicarbonate, chemistry, Blood bicarbonate, Age Groups, Physical Fitness, Athletes, People and Places, Population Groupings, Physiological Processes, Digestive System, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0df6725d129ad4badf5a1e6a7ed398Test
http://europepmc.org/articles/PMC8248647Test

6

Bioavailability of a Capsaicin Lipid Multi-particulate Formulation in Rats

المؤلفون: Aouatef Bellamine, Emre Sahin, Tyler White, Shane Durkee, Kelli Fowler, Kazim Sahin, Cemal Orhan, Osman Küçük

المصدر: European Journal of Drug Metabolism and Pharmacokinetics

مصطلحات موضوعية: Pharmacology, Clinical chemistry, Chemistry, Low dose, Cmax, Serum concentration, Bioavailability, chemistry.chemical_compound, Pharmacokinetics, Capsaicin, Time to peak, Pharmacology (medical), lipids (amino acids, peptides, and proteins), Original Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6734b8e181dc4632178ddeaea8ad6eadTest
https://avesis.erciyes.edu.tr/publication/details/68dd3e2a-84cb-409b-8b19-7f9c6799b64f/oaiTest

7

Investigation of the impact of grapefruit juice, pomegranate juice and tomato juice on pharmacokinetics of brexpiprazole in rats using UHPLC–QTOF–MS

المؤلفون: Amit Kumar Sahu, Pinaki Sengupta, Rajeshwari Rathod, Disha Thakkar, Abhijeet S. Kate

المصدر: Biomedical Chromatography. 35

مصطلحات موضوعية: Male, food.ingredient, Clinical Biochemistry, Herb-Drug Interactions, Thiophenes, Quinolones, 030226 pharmacology & pharmacy, 01 natural sciences, Biochemistry, Mass Spectrometry, Pomegranate, Grapefruit juice, Analytical Chemistry, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, food, Solanum lycopersicum, Pharmacokinetics, Limit of Detection, Drug Discovery, Animals, Food science, Molecular Biology, Chromatography, High Pressure Liquid, Brexpiprazole, Pharmacology, Chromatography, CYP3A4, Uhplc qtof ms, 010401 analytical chemistry, Area under the curve, Reproducibility of Results, General Medicine, Rats, 0104 chemical sciences, Fruit and Vegetable Juices, chemistry, Linear Models, Time to peak, Citrus paradisi

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f529a7777d53e14fb8a8f04b8327136Test
https://doi.org/10.1002/bmc.5201Test

8

The time to peak blood bicarbonate (HCO3−), pH, and strong ion difference (SID) following sodium bicarbonate (NaHCO3) ingestion in highly trained adolescent swimmers

المؤلفون: Lars R. McNaughton, Adam L. Kelly, S. Andy Sparks, Richard J Chessor, Josh W. Newbury, Matthew Cole, Lewis A. Gough

مصطلحات موضوعية: chemistry.chemical_compound, Animal science, Sodium bicarbonate, Pharmacokinetics, chemistry, Blood bicarbonate, Bicarbonate, medicine, Ingestion, Time to peak, medicine.symptom, Strong ion difference, Acidosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7e752f44666a8ba084da0f1889754dcbTest
https://doi.org/10.1101/2021.03.01.433339Test

9

Noninvasive quantitative assessment of microcirculatory disorders of the upper extremities with 2D fluorescence optical imaging

المؤلفون: Dominik Steubl, Sebastian Finsterer, Anne Helfen, Moritz Wildgruber, Ernst J. Rummeny, Reinhard Meier, Jan Neumann, Christoph Schmaderer, Markus T. Berninger, Alexander Zimmermann, Fabian Lohöfer

المصدر: Clinical Hemorheology and Microcirculation. 70:69-81

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc001e7a134a22f678812f8f114018d8Test
https://doi.org/10.3233/ch-170321Test

10

Increased Performance in Elite Runners Following Individualized Timing of Sodium Bicarbonate Supplementation

المؤلفون: Lars Lindstrøm, Tue A.H. Lassen, Klavs Madsen, Simon Lønbro

المصدر: International journal of sport nutrition and exercise metabolism. 31(6)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cd78307e3d0ea0cf241721c59ffc73Test
https://pubmed.ncbi.nlm.nih.gov/34470913Test

تنقيح النتائج