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المؤلفون: Becky A.S. Bibby, Ronnie Rodrigues Pereira, Ananya Choudhury, Kaye J. Williams, Elisabet More, Darragh G. McArt, Robert G. Bristow, Paul G. O’Reilly, N. Thiruthaneeswaran, Catharine M L West, Lingjian Yang
المصدر: Bibby, B A S, Thiruthaneeswaran, N, Yang, L, Pereira, R R, More, E, McArt, D G, O'Reilly, P, Bristow, R G, Williams, K J, Choudhury, A & West, C M L 2021, ' Repurposing FDA approved drugs as radiosensitizers for treating hypoxic prostate cancer ', BMC urology, vol. 21, no. 1, 96 . https://doi.org/10.1186/s12894-021-00856-xTest
BMC Urology
Bibby, B A S, Thiruthaneeswaran, N, Yang, L, Pereira, R R, More, E, McArt, D G, O'Reilly, P, Bristow, R G, Williams, K J, Choudhury, A & West, C M L 2021, ' Repurposing FDA approved drugs as radiosensitizers for treating hypoxic prostate cancer ', BMC Urology, vol. 21, no. 1, pp. 96 . https://doi.org/10.1186/s12894-021-00856-xTest
BMC Urology, Vol 21, Iss 1, Pp 1-11 (2021)مصطلحات موضوعية: 0301 basic medicine, Male, Radiation-Sensitizing Agents, Urology, 03 medical and health sciences, Prostate cancer, chemistry.chemical_compound, 0302 clinical medicine, Menadione, DU145, SDG 3 - Good Health and Well-being, Radioresistance, Cell Line, Tumor, LNCaP, Medicine, Humans, Clonogenic assay, Hypoxia, Manchester Cancer Research Centre, business.industry, United States Food and Drug Administration, ResearchInstitutes_Networks_Beacons/mcrc, Drug Repositioning, Prostatic Neoplasms, General Medicine, Hypoxia (medical), medicine.disease, Gemcitabine, Diseases of the genitourinary system. Urology, United States, 030104 developmental biology, Reproductive Medicine, chemistry, 030220 oncology & carcinogenesis, Cancer research, RC870-923, medicine.symptom, business, medicine.drug, Research Article
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96352efa42d651655e10ac31beee7b74Test
https://pure.manchester.ac.uk/ws/files/196449568/s12894_021_00856_x.pdfTest -
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المؤلفون: Marianne Ashford, Ian J. Stratford, Julio M. Rios de la Rosa, Alice Spadea, Nicola Tirelli, Manal Mehibel, Annalisa Tirella, Kaye J. Williams
المصدر: Molecular Pharmaceutics. 16:2481-2493
مصطلحات موضوعية: Gene isoform, media_common.quotation_subject, Cell, Pharmaceutical Science, 02 engineering and technology, Biology, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, Hyaluronic acid, medicine, Humans, Hyaluronic Acid, Receptor, Internalization, media_common, CD44, Cancer, Flow Cytometry, 021001 nanoscience & nanotechnology, medicine.disease, Immunohistochemistry, 3. Good health, Hyaluronan Receptors, medicine.anatomical_structure, chemistry, Cancer cell, biology.protein, Cancer research, Molecular Medicine, 0210 nano-technology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95e7d6baf0e17192457056c7c67ee96Test
https://doi.org/10.1021/acs.molpharmaceut.9b00083Test -
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المؤلفون: Caroline Kelly, Karin Williams, Stephen T. Durant, Sarah Derby, Kaye J. Williams, Rodrigo Gutierrez-Quintana, Anthony J. Chalmers, Mark R. Jackson, Jon Stobo, David Walker, Lorna Sweeting, Duncan Forster
المصدر: Clinical Cancer Research. 27:IA-006
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Temozolomide, Performance status, business.industry, medicine.medical_treatment, Brain tumor, Phases of clinical research, Cancer, medicine.disease, Olaparib, Radiation therapy, chemistry.chemical_compound, Therapeutic index, chemistry, Internal medicine, medicine, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::54e2112bab2e989e3e09e26abc9ea0b1Test
https://doi.org/10.1158/1557-3265.radsci21-ia-006Test -
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المؤلفون: Timothy W. Wallace, John A. Hadfield, Steven B. Rossington, Kaye J. Williams, Steven D. Shnyder
المصدر: Rossington, S, Hadfield, J, Shnyder, S D, Wallace, T & Williams, K 2017, ' Tubulin-binding dibenz[c,e]oxepines : Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents ', Bioorganic and Medicinal Chemistry, vol. 25, no. 5, pp. 1630-1642 . https://doi.org/10.1016Test/j.bmc.2017.01.027
مصطلحات موضوعية: Necrosis, Clinical Biochemistry, Pharmaceutical Science, Tumour vasculature, 01 natural sciences, Biochemistry, Tubulin binding, Structural variation, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tubulin, Cell Line, Tumor, Neoplasms, Biological property, Drug Discovery, Journal Article, medicine, Animals, Humans, Colchicine, Molecular Biology, Biological evaluation, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, direct arylation, Organic Chemistry, palladium catalyst, 0104 chemical sciences, tubulin, chemistry, Cell culture, 030220 oncology & carcinogenesis, biology.protein, Heterografts, Molecular Medicine, medicine.symptom, Dibenzoxepins
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7159b0428917a521e7ecb361504f199Test
https://doi.org/10.1016Test/j .bmc.2017.01.027 -
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المؤلفون: Andrew P. Badrock, Jivko Kamarashev, Irene Barinaga-Rementeria Ramirez, Duncan Forster, Katherine A. Hollywood, Emmanuelle Claude, Adam Hurlstone, B. Ewa Snaar-Jagalska, Michael Green, Herman P. Spaink, Adam McMahon, Christos Evangelou, Hannah R Johnston, Warwick B. Dunn, Michael Fairclough, Shuning He, Fiona Henderson, Kaye J. Williams, Paul Lorigan, Michael P. Smith, Raghavendar Nagaraju, Emrys A. Jones
المصدر: Henderson, F, Johnston, H, Badrock, A, Jones, E, Forster, D, Nagaraju, R, Evangelou, C, Kamarashev, J, Green, M, Fairclough, M, Barinaga-Rementeria, I, He, S, Jagalska, E S, Hollywood, K, Dunn, W, Spaink, H P, Smith, M, Lorigan, P, Claude, E, Williams, K, Mcmahon, A & Hurlstone, A 2019, ' Enhanced fatty acid scavenging and glycerophospholipid metabolism accompanies melanocyte neoplasia progression in zebrafish ', Cancer Research, vol. 79, no. 9, pp. 2136-2151 . https://doi.org/10.1158/0008-5472.can-18-2409Test
Cancer Research, 79(9), 2136-2151
Cancer Researchمصطلحات موضوعية: 0301 basic medicine, Cancer Research, Phospholipid, Glycerophospholipids, Palmitic acid, Transcriptome, Mass Spectrometry Imaging, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Manchester Institute of Biotechnology, Tumor Cells, Cultured, Animals, Humans, Metabolomics, Zebrafish, Melanoma, chemistry.chemical_classification, Lipoprotein lipase, Microphthalmia-Associated Transcription Factor, biology, Fatty Acids, Fatty acid, Lipid metabolism, Zebrafish Proteins, biology.organism_classification, Lipid Metabolism, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Fatty acid synthase, Lipoprotein Lipase, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer research, biology.protein, ras Proteins, Melanocytes, LPL, Fatty Acid Synthases, Energy Metabolism, Transcriptome Analysis, Fatty Acid
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3528b41f2ca92becf293b08a708b55Test
https://pubmed.ncbi.nlm.nih.gov/30862716Test -
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المؤلفون: D. Walker, Kaye J. Williams, R. Gutierrez-Quintana, N. Gomez-Roman, Anthony J. Chalmers, S.T. Durant
المصدر: Radiotherapy and Oncology. 152:S311
مصطلحات موضوعية: chemistry.chemical_compound, Oncology, chemistry, Radiology, Nuclear Medicine and imaging, Hematology, Penetrant (biochemical), Neural stem cell, Cell biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f030d46bb4776123674f7db8f3076280Test
https://doi.org/10.1016/s0167-8140Test(21)00580-6 -
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المؤلفون: Gavin Brown, Muhammad Babur, Alison Smigova, Christopher Cawthorne, Kaye J. Williams, Paul Birkket, Manikandan Kadirvel, Emily J. Rowling, Michael Fairclough, Adam McMahon, Sally Freeman
المصدر: Bioorganic & Medicinal Chemistry. 22:341-349
مصطلحات موضوعية: integumentary system, Chemistry, Stereochemistry, organic chemicals, Organic Chemistry, Clinical Biochemistry, Radiosynthesis, Pharmaceutical Science, Halogenation, complex mixtures, Biochemistry, Small molecule, In vitro, chemistry.chemical_compound, Nucleophile, In vivo, Yield (chemistry), Drug Discovery, Molecular Medicine, Molecular Biology, Fluoride, Nuclear chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cb2d029480028deca027fa40e2445bd3Test
https://doi.org/10.1016Test/j .bmc.2013.11.019 -
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المؤلفون: Nicholas P. Lockyer, John S. Fletcher, John C. Vickerman, Alex Henderson, Helen L. Kotze, Kaye J. Williams, Emily G. Armitage
المصدر: Surface and Interface Analysis. 45:277-281
مصطلحات موضوعية: chemistry.chemical_classification, Biomolecule, Metabolite, Surfaces and Interfaces, General Chemistry, Computational biology, Condensed Matter Physics, Surfaces, Coatings and Films, Secondary ion mass spectrometry, chemistry.chemical_compound, Drug treatment, Metabolomics, Nuclear magnetic resonance, chemistry, Potential biomarkers, Principal component analysis, Chemical specificity, Materials Chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4b74bcc2885fc47361cebe4e2e57a05fTest
https://doi.org/10.1002/sia.5055Test -
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المؤلفون: Sophie Ridsdale, Melissa Mejin, Julia Resch, Emily J. Rowling, Kaye J. Williams, Muhammad Babur, Natalie Burrows, Georg Brabant
المصدر: The Journal of Clinical Endocrinology & Metabolism; Vol 96
The Journal of Clinical Endocrinology & Metabolismمصطلحات موضوعية: Vascular Endothelial Growth Factor A, medicine.medical_specialty, Indazoles, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Antineoplastic Agents, Biochemistry, Thyroid carcinoma, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cell Movement, Internal medicine, Tumor Cells, Cultured, medicine, Animals, Humans, PTEN, Tensin, Thyroid Neoplasms, PI3K/AKT/mTOR pathway, Cell Proliferation, 030304 developmental biology, Sulfonamides, 0303 health sciences, biology, Carcinoma, Biochemistry (medical), Thyroid, PTEN Phosphohydrolase, Hypoxia-Inducible Factor 1, alpha Subunit, Cell Hypoxia, 3. Good health, Vascular endothelial growth factor, Vascular endothelial growth factor A, medicine.anatomical_structure, Hypoxia-inducible factors, chemistry, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a2b2277b2b7af2a4a51fd7effb18bdTest
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المؤلفون: Brian A. Telfer, Stephen R. Wedge, Kaye J. Williams, Ian J. Stratford, Aoife M. Shannon, M. Babur
المصدر: The British Journal of Radiology. 81:S21-S27
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Pathology, medicine.medical_specialty, Lung Neoplasms, Endothelium, medicine.medical_treatment, Mice, Nude, Apoptosis, Cediranib, Mice, Necrosis, chemistry.chemical_compound, Radioresistance, Animals, Medicine, Radiology, Nuclear Medicine and imaging, business.industry, Growth factor, Carcinoma, General Medicine, Hypoxia (medical), Combined Modality Therapy, Radiation therapy, Vascular endothelial growth factor, medicine.anatomical_structure, chemistry, Concomitant, Quinazolines, Cancer research, Female, medicine.symptom, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78c39cc253814386e216d3a9f95973aTest
https://doi.org/10.1259/bjr/59853976Test